| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2003PNAS..100.3410W |
| P356 | DOI | 10.1073/PNAS.0530278100 |
| P932 | PMC publication ID | 152306 |
| P698 | PubMed publication ID | 12624183 |
| P5875 | ResearchGate publication ID | 8050904 |
| P50 | author | Pamela Russell | Q18166584 |
| Robyn Ward | Q30503543 | ||
| David I Quinn | Q38327794 | ||
| Nicholas J. Hawkins | Q43280190 | ||
| Christopher Moskaluk | Q57441216 | ||
| Tao Liu | Q62749725 | ||
| P2093 | author name string | Robert L Sutherland | |
| Garret M Hampton | |||
| David A Brown | |||
| Asne R Bauskin | |||
| Samuel N Breit | |||
| Henry F Frierson | |||
| John B Welsh | |||
| Lisa M Sapinoso | |||
| Suzanne G Kern | |||
| P2860 | cites work | The Hallmarks of Cancer | Q221226 |
| Gene ontology: tool for the unification of biology | Q23781406 | ||
| MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily | Q24317134 | ||
| Cluster analysis and display of genome-wide expression patterns | Q24644463 | ||
| A new method for predicting signal sequence cleavage sites | Q27861117 | ||
| Relaxin: a pleiotropic hormone | Q28235662 | ||
| Maspin. A tumor suppressing serpin | Q28259247 | ||
| Maspin | Q29039847 | ||
| RefSeq and LocusLink: NCBI gene-centered resources | Q29547259 | ||
| Large-scale analysis of the human and mouse transcriptomes | Q29547360 | ||
| Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses | Q29616071 | ||
| Large-scale identification of secreted and membrane-associated gene products using DNA microarrays | Q31704628 | ||
| Mammaglobin, a breast-specific gene, and its utility as a marker for breast cancer | Q33934229 | ||
| The role of serum alpha-fetoprotein estimation in the diagnosis and management of hepatocellular carcinoma | Q34162174 | ||
| Autocrine and paracrine signaling through neuropeptide receptors in human cancer | Q34225976 | ||
| CA 15-3: a prognostic marker in breast cancer. | Q34646993 | ||
| Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer | Q34652960 | ||
| Bioinformatic identification of potential autocrine signaling loops in cancers from gene expression profiles | Q38295259 | ||
| Osteopontin as a potential diagnostic biomarker for ovarian cancer | Q38457189 | ||
| Linking gene expression patterns to therapeutic groups in breast cancer | Q38465258 | ||
| Autocrine growth factors and cancer | Q39815279 | ||
| The transforming growth factor-ss superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women. | Q40835101 | ||
| Bombesin receptor antagonists | Q41186661 | ||
| Human kallikrein 10: a novel tumor marker for ovarian carcinoma? | Q43562015 | ||
| Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer | Q43708520 | ||
| Prostasin, a potential serum marker for ovarian cancer: identification through microarray technology | Q43754824 | ||
| Antibody-based approach to high-volume genotyping for MIC-1 polymorphism | Q44077970 | ||
| Molecular classification of human carcinomas by use of gene expression signatures. | Q45967210 | ||
| Elevation of cerebrospinal fluid soluble CD27 levels in patients with meningeal localization of lymphoid malignancies | Q49101199 | ||
| Prediction of membrane protein topology utilizing multiple sequence alignments. | Q52260817 | ||
| TMAP: a new email and WWW service for membrane-protein structural predictions. | Q52343546 | ||
| Human kallikrein 6 (zyme/protease M/neurosin): a new serum biomarker of ovarian carcinoma | Q57942914 | ||
| Gastrin-releasing peptide gene expression in small cell and large cell undifferentiated lung carcinomas | Q61758559 | ||
| Identifying markers for pancreatic cancer by gene expression analysis | Q74263354 | ||
| Secreted and cell surface genes expressed in benign and malignant colorectal tumors | Q74590931 | ||
| Evaluation of soluble CD44 in patients with breast and colorectal carcinomas and non-Hodgkin's lymphoma | Q78056533 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | biomarker | Q864574 |
| overexpression | Q61643320 | ||
| P304 | page(s) | 3410-3415 | |
| P577 | publication date | 2003-03-06 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum | |
| P478 | volume | 100 |
| Q33830172 | A Boolean-based systems biology approach to predict novel genes associated with cancer: Application to colorectal cancer. |
| Q42745683 | A New Transgenic Mouse Model of Heart Failure and Cardiac Cachexia Raised by Sustained Activation of Met Tyrosine Kinase in the Heart. |
| Q64061660 | A Systematic Investigation of the Malignant Functions and Diagnostic Potential of the Cancer Secretome |
| Q57167377 | A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup |
| Q35083829 | A hot new twist to hair biology: involvement of vanilloid receptor-1 (VR1/TRPV1) signaling in human hair growth control |
| Q40596797 | A novel time-course cDNA microarray analysis method identifies genes associated with the development of cisplatin resistance |
| Q33877005 | Activation of NAG-1 via JNK signaling revealed an isochaihulactone-triggered cell death in human LNCaP prostate cancer cells |
| Q37790673 | Advances in pancreatic cancer detection |
| Q38344964 | Altered gene expression in acute systemic inflammation detected by complete coverage of the human liver transcriptome |
| Q33648678 | An autocrine/paracrine circuit of growth differentiation factor (GDF) 15 has a role for maintenance of breast cancer stem-like cells |
| Q38653870 | Anorexia-cachexia and obesity treatment may be two sides of the same coin: role of the TGF-b superfamily cytokine MIC-1/GDF15. |
| Q33813605 | Anorexia-cachexia syndrome in hepatoma tumour-bearing rats requires the area postrema but not vagal afferents and is paralleled by increased MIC-1/GDF15. |
| Q36421073 | Anorexia/cachexia of chronic diseases: a role for the TGF-β family cytokine MIC-1/GDF15. |
| Q35728009 | Anti-inflammatory agent indomethacin reduces invasion and alters metabolism in a human breast cancer cell line |
| Q33200797 | Applications of a rat multiple tissue gene expression data set. |
| Q33630913 | BRCA1 represses amphiregulin gene expression |
| Q34239193 | Bioinformatic identification of proteins with tissue-specific expression for biomarker discovery |
| Q38089821 | Biomarkers in the diagnosis and early detection of pancreatic cancer |
| Q40079230 | Border length minimization problem on a square array |
| Q36635956 | COX inhibitors directly alter gene expression: role in cancer prevention? |
| Q47236468 | Calsyntenin-1, clusterin and neutrophil gelatinase-associated lipocalin are candidate serological biomarkers for lung adenocarcinoma. |
| Q36351359 | Catalytic deoxyribozyme-modified nanoparticles for RNAi-independent gene regulation |
| Q35106132 | Change of body weight and macrophage inhibitory cytokine-1 during chemotherapy in advanced gastric cancer: what is their clinical significance? |
| Q40097264 | Characterization of arecoline-induced effects on cytotoxicity in normal human gingival fibroblasts by global gene expression profiling. |
| Q64974281 | Circulating growth/differentiation factor 15 is associated with human CD56bright natural killer cell dysfunction and nosocomial infection in severe systemic inflammation. |
| Q39173145 | Circulating levels of GDF15, MMP7 and miR-200c as a poor prognostic signature in gastric cancer |
| Q39012529 | Combined therapeutic effects of vinblastine and Astragalus saponins in human colon cancer cells and tumor xenograft via inhibition of tumor growth and proangiogenic factors. |
| Q39604837 | Comparison of alternative extraction methods for secretome profiling in human hepatocellular carcinoma cells |
| Q36924060 | Computational prediction of human proteins that can be secreted into the bloodstream |
| Q52562759 | Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer. |
| Q41963820 | Cryptophane xenon-129 nuclear magnetic resonance biosensors targeting human carbonic anhydrase |
| Q38089767 | Cytokines as potential tumour markers. |
| Q35098017 | DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines |
| Q36672816 | Databases of free expression |
| Q35812532 | Development and use of biomarkers in oncology drug development |
| Q35110096 | Diagnostic performance of serum macrophage inhibitory cytokine-1 in pancreatic cancer: a meta-analysis and meta-regression analysis |
| Q37441231 | Differential secreted proteome approach in murine model for candidate biomarker discovery in colon cancer |
| Q36094396 | Differentiated embryo-chondrocyte expressed gene 1 regulates p53-dependent cell survival versus cell death through macrophage inhibitory cytokine-1. |
| Q34099900 | Divergent molecular mechanisms underlying the pleiotropic functions of macrophage inhibitory cytokine-1 in cancer |
| Q46195126 | Does the 3-gene diagnostic assay accurately distinguish benign from malignant thyroid neoplasms? |
| Q38501336 | Dual blockade of PKA and NF-κB inhibits H2 relaxin-mediated castrate-resistant growth of prostate cancer sublines and induces apoptosis |
| Q47893482 | Dysregulated expression of MIC-1/PDF in human prostate tumor cells |
| Q38412532 | Early Epithelial Restitution by Nonsteroidal Anti-Inflammatory Drug-Activated Gene 1 Counteracts Intestinal Ulcerative Injuries |
| Q57066655 | Effects of non-steroidal anti-inflammatory drug-activated gene-1 on Ganoderma lucidum polysaccharides-induced apoptosis of human prostate cancer PC-3 cells |
| Q47985560 | Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure. |
| Q41093240 | Elevated serum growth differentiation factor 15 levels are associated with thyroid nodules in type 2 diabetes aged over 60 years |
| Q38452303 | Enteropathogenic Escherichia coli-induced macrophage inhibitory cytokine 1 mediates cancer cell survival: an in vitro implication of infection-linked tumor dissemination |
| Q45883725 | Erythropoiesis-driven regulation of hepcidin in human red cell disorders is better reflected through concentrations of soluble transferrin receptor rather than growth differentiation factor 15. |
| Q26827810 | Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds. |
| Q40233446 | Expression of cyclooxygenase-2 mRNA in peripheral blood of head and neck cancer patients and in healthy controls. A pilot study. |
| Q34600781 | Expression profiling of PC-3 cell line variants and comparison of MIC-1 transcript levels in benign and malignant prostate |
| Q36728674 | GDF 15--A Novel Biomarker in the Offing for Heart Failure |
| Q26798142 | GDF-15 as a Target and Biomarker for Diabetes and Cardiovascular Diseases: A Translational Prospective |
| Q28535575 | GDF-15 for prognostication of cardiovascular and cancer morbidity and mortality in men |
| Q92973308 | GDF-15 in solid vs non-solid treatment-naïve malignancies |
| Q36982817 | GDF-15 protects from macrophage accumulation in a mousemodel of advanced atherosclerosis |
| Q34007029 | GDF-15: a novel serum marker for metastases in uveal melanoma patients. |
| Q64061570 | GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans |
| Q59807334 | GDF15 and Growth Control |
| Q52326010 | GDF15 promotes the proliferation of cervical cancer cells by phosphorylating AKT1 and Erk1/2 through the receptor ErbB2. |
| Q33860352 | Gene expression changes during HPV-mediated carcinogenesis: a comparison between an in vitro cell model and cervical cancer |
| Q36812689 | Genetic variability in inflammation pathways and prostate cancer risk |
| Q38453453 | Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15 |
| Q36718611 | Genomic signatures in non-small-cell lung cancer: targeting the targeted therapies |
| Q90460790 | Growth Differentiation Factor-15 (GDF-15) is a Biomarker of Muscle Wasting and Renal Dysfunction in Preoperative Cardiovascular Surgery Patients |
| Q35316842 | Growth differentiation factor 15 (GDF15)-mediated HER2 phosphorylation reduces trastuzumab sensitivity of HER2-overexpressing breast cancer cells |
| Q88537974 | Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice |
| Q38886357 | Growth differentiation factor 15 as a radiation-induced marker in oral carcinoma increasing radiation resistance |
| Q33908936 | Growth differentiation factor 15 in erythroid health and disease |
| Q37117179 | Growth differentiation factor 15 is a promising diagnostic and prognostic biomarker in colorectal cancer |
| Q47121253 | Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling |
| Q35087191 | Growth differentiation factor 15 stimulates rapamycin-sensitive ovarian cancer cell growth and invasion |
| Q35006757 | Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer |
| Q84472567 | Growth differentiation factor-15 as a prognostic biomarker in ovarian cancer |
| Q90369225 | Growth differentiation factor-15 combined with N-terminal prohormone of brain natriuretic peptide increase 1-year prognosis prediction value for patients with acute heart failure: a prospective cohort study |
| Q36893044 | Growth differentiation factor-15 is associated with muscle mass in chronic obstructive pulmonary disease and promotes muscle wasting in vivo. |
| Q35021094 | Growth-differentiation factor-15 is a robust, independent predictor of 11-year mortality risk in community-dwelling older adults: the Rancho Bernardo Study |
| Q37988746 | Growth/differentiation factor-15: prostate cancer suppressor or promoter? |
| Q56490134 | High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin |
| Q35641788 | How industry is approaching the search for new diagnostic markers and biomarkers |
| Q43016165 | IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis with its expression associated with DNA hypomethylation of exon 1. |
| Q31005059 | Identification of biomarkers for ovarian cancer using strong anion-exchange ProteinChips: potential use in diagnosis and prognosis |
| Q34981475 | Identification of diagnostic serum protein profiles of glioblastoma patients |
| Q35000491 | Identification of patients with nasopharyngeal carcinoma by serum protein profiling using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry |
| Q37185019 | Identification of potential lung cancer biomarkers using an in vitro carcinogenesis model |
| Q31039610 | Identification of serum biomarkers for lung cancer using magnetic bead-based SELDI-TOF-MS. |
| Q34159066 | Identifying FGA peptides as nasopharyngeal carcinoma-associated biomarkers by magnetic beads |
| Q39188239 | In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion. |
| Q35497551 | Integrated proteomic profiling of cell line conditioned media and pancreatic juice for the identification of pancreatic cancer biomarkers |
| Q37728847 | Integrating high-throughput technologies in the quest for effective biomarkers for ovarian cancer |
| Q33382997 | Integrative genomic data mining for discovery of potential blood-borne biomarkers for early diagnosis of cancer |
| Q36563056 | Kallikreins - The melting pot of activity and function |
| Q35475302 | MIC-1/GDF15 in Barrett's oesophagus and oesophageal adenocarcinoma |
| Q34045939 | Macrophage inhibitory cytokine 1 (MIC-1/GDF15) as a novel diagnostic serum biomarker in pancreatic ductal adenocarcinoma |
| Q35325174 | Macrophage inhibitory cytokine 1 biomarker serum immunoassay in combination with PSA is a more specific diagnostic tool for detection of prostate cancer |
| Q36570789 | Macrophage inhibitory cytokine 1: a new prognostic marker in prostate cancer |
| Q35563909 | Macrophage inhibitory cytokine-1 (MIC-1/GDF15) gene deletion promotes cancer growth in TRAMP prostate cancer prone mice |
| Q34405669 | Macrophage inhibitory cytokine-1 (MIC-1/GDF15) slows cancer development but increases metastases in TRAMP prostate cancer prone mice |
| Q34072831 | Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality |
| Q40015389 | Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells. |
| Q39946272 | Macrophage inhibitory cytokine-1 is overexpressed in malignant melanoma and is associated with tumorigenicity |
| Q33882542 | Macrophage inhibitory cytokine-1 regulates melanoma vascular development |
| Q54944542 | Macrophage inhibitory cytokine-1 versus carbohydrate antigen 19-9 as a biomarker for diagnosis of pancreatic cancer: A PRISMA-compliant meta-analysis of diagnostic accuracy studies. |
| Q38751466 | Macrophage inhibitory cytokine-1/growth differentiation factor-15 as a predictor of colonic neoplasia. |
| Q93197174 | Macrophage inhibitory cytokine-1/growth differentiation factor-15 in premalignant and neoplastic tumours in a high-risk pancreatic cancer cohort |
| Q37369895 | Macrophage inhibitory cytokine-1: a new player in melanoma development |
| Q35051499 | Macrophage inhibitory factor 1 acts as a potential biomarker in patients with esophageal squamous cell carcinoma and is a target for antibody-based therapy |
| Q36746688 | Marked improvement of cytotoxic effects induced by docetaxel on highly metastatic and androgen-independent prostate cancer cells by downregulating macrophage inhibitory cytokine-1. |
| Q30751781 | Mass spectrometry as a diagnostic and a cancer biomarker discovery tool: opportunities and potential limitations |
| Q36680064 | Mass spectrometry: uncovering the cancer proteome for diagnostics |
| Q35116080 | Microarray technologies 2003 -- an overview. |
| Q36440214 | Molecular Mechanisms of Trastuzumab-Based Treatment in HER2-Overexpressing Breast Cancer |
| Q35175438 | Molecular prognostication in bladder cancer--a current perspective. |
| Q47619196 | Multiclass cancer classification and biomarker discovery using GA-based algorithms |
| Q37687793 | NSAID-activated gene 1 mediates pro-inflammatory signaling activation and paclitaxel chemoresistance in type I human epithelial ovarian cancer stem-like cells |
| Q36625481 | Neutrophil gelatinase-associated lipocalin, macrophage inhibitory cytokine 1, and carbohydrate antigen 19-9 in pancreatic juice: pathobiologic implications in diagnosing benign and malignant disease of the pancreas |
| Q24620497 | Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK-RhoA signaling pathway |
| Q34328127 | Overexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic origin |
| Q34675545 | P38 MAPK contributes to resistance and invasiveness of HER2- overexpressing breast cancer |
| Q64262554 | Peptidase inhibitor 15 as a novel blood diagnostic marker for cholangiocarcinoma |
| Q33723662 | Plasma MIC-1 correlates with systemic inflammation but is not an independent determinant of nutritional status or survival in oesophago-gastric cancer |
| Q28476378 | Prediction of body fluids where proteins are secreted into based on protein interaction network |
| Q35648859 | Promising directions for the diagnosis and management of gynecological cancers |
| Q91521072 | Prostate cancer promotes a vicious cycle of bone metastasis progression through inducing osteocytes to secrete GDF15 that stimulates prostate cancer growth and invasion |
| Q41790919 | Protective Effects of Liposomal N-Acetylcysteine against Paraquat-Induced Cytotoxicity and Gene Expression |
| Q45948712 | Protein biomarker druggability profiling. |
| Q40448446 | Protein kinase C-dependent regulation of NAG-1/placental bone morphogenic protein/MIC-1 expression in LNCaP prostate carcinoma cells. |
| Q36520462 | Proteomic Profiling of Serum-Derived Exosomes from Ethnically Diverse Prostate Cancer Patients |
| Q36026306 | Proteomic profiling of pancreatic cancer for biomarker discovery |
| Q39128591 | RNPC1, an RNA-binding protein and a p53 target, regulates macrophage inhibitory cytokine-1 (MIC-1) expression through mRNA stability |
| Q35810123 | Recent progress in predictive biomarkers for metastatic recurrence of human hepatocellular carcinoma: a review of the literature |
| Q47129121 | Relevance of MIC-1 in the Era of PSA as a Serum Based Predictor of Prostate Cancer: A Critical Evaluation |
| Q89601774 | Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury |
| Q36682379 | Sample preparation for serum/plasma profiling and biomarker identification by mass spectrometry |
| Q92467866 | Senescence-associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15 |
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| Q35711126 | Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI. |
| Q84749791 | Serum cytokine levels in patients with advanced non-small cell lung cancer: correlation with treatment response and survival |
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| Q44397438 | Serum hepcidin and growth differentiation factor-15 (GDF-15) levels in polycythemia vera and essential thrombocythemia |
| Q43690125 | Serum macrophage inhibitory cytokine-1 (MIC-1/GDF15): a potential screening tool for the prevention of colon cancer? |
| Q60620984 | Solid Stress Facilitates Fibroblasts Activation to Promote Pancreatic Cancer Cell Migration |
| Q37132800 | State of the art in tumor antigen and biomarker discovery. |
| Q24813666 | Storing, linking, and mining microarray databases using SRS |
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| Q36647686 | TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator |
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| Q40325392 | The R273H p53 mutation can facilitate the androgen-independent growth of LNCaP by a mechanism that involves H2 relaxin and its cognate receptor LGR7. |
| Q39492314 | The TGF-β superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism. |
| Q33817236 | The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract |
| Q36926612 | The cancer secretome: a reservoir of biomarkers |
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| Q40056643 | Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1. |
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