GDF-15 as a Target and Biomarker for Diabetes and Cardiovascular Diseases: A Translational Prospective

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GDF-15 as a Target and Biomarker for Diabetes and Cardiovascular Diseases: A Translational Prospective is …
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P356DOI10.1155/2015/490842
P3181OpenCitations bibliographic resource ID396942
P932PMC publication ID4530250
P698PubMed publication ID26273671
P5875ResearchGate publication ID275954335

P2093author name stringSanjay K Banerjee
Ramu Adela
P2860cites workA comprehensive review on metabolic syndromeQ21284500
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MIC-1 is a novel TGF-beta superfamily cytokine associated with macrophage activationQ77787092
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Growth-differentiation factor-15: a novel biomarker in patients with diastolic dysfunction?Q84126763
Multimarker approach for the prediction of cardiovascular events in patients with mild to moderate coronary artery lesions. A 3-year follow-up studyQ84355521
Circulating growth differentiation factor-15 correlates with myocardial fibrosis in patients with non-ischaemic dilated cardiomyopathy and decreases rapidly after left ventricular assist device supportQ84658437
The story of growth differentiation factor 15: another piece of the puzzleQ85199125
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Growth-differentiation factor-15 and major cardiac eventsQ87280167
Usefulness of growth differentiation factor-15 levels to predict diabetic cardiomyopathy in asymptomatic patients with type 2 diabetes mellitusQ87466369
Increased serum levels of GDF-15 associated with mortality and subclinical atherosclerosis in patients on maintenance hemodialysisQ87560591
[Value of plasma growth differentiation factor-15 in diagnosis and evaluation of type 2 diabetic nephropathy]Q95571566
Plasma growth differentiation factor-15 independently predicts all-cause and cardiovascular mortality as well as deterioration of kidney function in type 1 diabetic patients with nephropathyQ33932770
Olmesartan prevents cardiac rupture in mice with myocardial infarction by modulating growth differentiation factor 15 and p53Q34025188
NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolismQ34054078
Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortalityQ34072831
Growth differentiation factor-15 (GDF-15) levels are associated with cardiac and renal injury in patients undergoing coronary artery bypass grafting with cardiopulmonary bypassQ34110286
Circulating and placental growth-differentiation factor 15 in preeclampsia and in pregnancy complicated by diabetes mellitusQ34206335
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The novel biomarker growth differentiation factor 15 in heart failure with normal ejection fractionQ34343385
The Association of Growth Differentiation Factor-15 with Left Ventricular Hypertrophy in Hypertensive PatientsQ34447208
Unilateral nodular diabetic glomerulosclerosis (Kimmelstiel-Wilson): report of a caseQ34699836
Cause-specific excess deaths associated with underweight, overweight, and obesityQ34711194
Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell deathQ34986193
The renal transcriptome of db/db mice identifies putative urinary biomarker proteins in patients with type 2 diabetes: a pilot studyQ35924547
An immune origin of type 2 diabetes?Q36112058
Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancerQ36481328
Modified low density lipoprotein delivers substrate for ceramide formation and stimulates the sphingomyelin-ceramide pathway in human macrophagesQ36852827
GDF15 triggers homeostatic proliferation of acid-secreting collecting duct cellsQ36906059
Potential biomarkers of ageing.Q37061417
PTGF-beta, a type beta transforming growth factor (TGF-beta) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-beta signaling pathwayQ37143062
Association of Growth Differentiation Factor-15 with Coronary Atherosclerosis and Mortality in a Young, Multiethnic Population: Observations from the Dallas Heart StudyQ37588805
Biomarkers of cardiovascular stress and incident chronic kidney diseaseQ37678391
Growth differentiation factor (GDF)-15 blocks norepinephrine-induced myocardial hypertrophy via a novel pathway involving inhibition of epidermal growth factor receptor transactivationQ37683299
Prevalence of left-ventricular hypertrophy in hypertension: an updated review of echocardiographic studiesQ37960351
Growth Differentiation Factor 15 in Heart Failure: An UpdateQ38041973
Growth differentiation factor 15 and cardiovascular events in patients with stable ischemic heart disease (The Heart and Soul Study).Q38179689
Growth differentiation factor 15 acts anti-apoptotic and pro-hypertrophic in adult cardiomyocytesQ38345677
Growth differentiation factor 15, a marker of oxidative stress and inflammation, for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARIQ38422565
Growth differentiation factor 15 predicts future insulin resistance and impaired glucose control in obese nondiabetic individuals: results from the XENDOS trialQ39564409
Serial measurement of growth-differentiation factor-15 in heart failure: relation to disease severity and prognosis in the Valsartan Heart Failure Trial.Q39835614
p53 controls prostate-derived factor/macrophage inhibitory cytokine/NSAID-activated gene expression in response to cell density, DNA damage and hypoxia through diverse mechanismsQ39902879
Growth differentiation factor-15: a new biomarker in cardiovascular diseaseQ39917432
Growth-differentiation factor-15 is an independent marker of cardiovascular dysfunction and disease in the elderly: results from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) StudyQ39967372
Measurement of serum levels of macrophage inhibitory cytokine 1 combined with prostate-specific antigen improves prostate cancer diagnosisQ40359911
The transforming growth factor-beta family members bone morphogenetic protein-2 and macrophage inhibitory cytokine-1 as mediators of the antiangiogenic activity of N-(4-hydroxyphenyl)retinamideQ40408743
The propeptide mediates formation of stromal stores of PROMIC-1: role in determining prostate cancer outcomeQ40436424
Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancersQ40568605
Acute systemic inflammation impairs endothelium-dependent dilatation in humansQ40616085
Growth Differentiation Factor‐15 Deficiency Inhibits Atherosclerosis Progression by Regulating Interleukin‐6–Dependent Inflammatory Response to Vascular InjuryQ41831221
Signaling of Reactive Oxygen and Nitrogen Species in Diabetes MellitusQ41870434
Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxisQ42288906
Apoptosis caused by oxidized LDL is manganese superoxide dismutase and p53 dependentQ42543771
Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytesQ42805165
Macrophage inhibitory cytokine-1 is increased in individuals before type 2 diabetes diagnosis but is not an independent predictor of type 2 diabetes: the Whitehall II studyQ43157318
Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancerQ43708520
Prevalence and relevant factors on echocardiographic left ventricular hypertrophy among community-based hypertensive patients in ShanghaiQ44201376
Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells.Q44564112
Growth differentiation factor 15 can distinguish between hypertrophic cardiomyopathy and hypertensive heartsQ44871151
Involvement of growth differentiation factor-15/macrophage inhibitory cytokine-1 (GDF-15/MIC-1) in oxLDL-induced apoptosis of human macrophages in vitro and in arteriosclerotic lesionsQ45086910
Myocardial infarction enhances progressive renal damage in an experimental model for cardio-renal interactionQ45173402
Genetic deletion of growth differentiation factor 15 augments renal damage in both type 1 and type 2 models of diabetesQ45177029
Multiple marker approach to risk stratification in patients with stable coronary artery diseaseQ45573743
Increased serum concentrations of macrophage inhibitory cytokine-1 in patients with obesity and type 2 diabetes mellitus: the influence of very low calorie diet.Q45974276
Influence of postprandial triglyceride-rich lipoproteins on lipid-mediated gene expression in smooth muscle cells of the human coronary arteryQ46527093
High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathwayQ46560274
Gene expression pattern in biomechanically stretched cardiomyocytes: evidence for a stretch-specific gene programQ46833890
Caspase-3 and tissue factor expression in lipid-rich plaque macrophages: evidence for apoptosis as link between inflammation and atherothrombosisQ47780850
Growth differentiation factor-15 in the early diagnosis and risk stratification of patients with acute chest painQ48742918
Growth differentiation factor-15 as a prognostic marker in patients with acute myocardial infarctionQ48788412
Association between cardiac biomarkers and the development of ESRD in patients with type 2 diabetes mellitus, anemia, and CKD.Q48960842
Increased number of islet-associated macrophages in type 2 diabetes.Q53545508
Growth differentiation factor 15, ischemia modified albumin and pregnancy-associated plasma protein A in patients with coronary artery disease.Q54338426
GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation.Q54623768
Growth Differentiation Factor 15 for Risk Stratification and Selection of an Invasive Treatment Strategy in Non ST-Elevation Acute Coronary SyndromeQ56593478
Growth/differentiation factor-15/macrophage inhibitory cytokine-1 is a novel trophic factor for midbrain dopaminergic neurons in vivoQ57248441
Polarised secretion of cytokines in primary human microvascular endothelial cells is not dependent on N-linked glycosylationQ57359961
Prognostic Utility of Growth Differentiation Factor-15 in Patients With Chronic Heart FailureQ57422717
Colocalization of CPP-32 With Apoptotic Cells in Human Atherosclerotic PlaquesQ58150467
The Relationship between Insulin Resistance and the Cardiovascular Biomarker Growth Differentiation Factor-15 in Obese PatientsQ58788278
GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in miceQ58807888
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectbiomarkerQ864574
diabetesQ12206
peptideQ172847
cardiovascular diseaseQ389735
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)490842
P577publication date2015-07-27
P13046publication type of scholarly workreview articleQ7318358
P1433published inJournal of Diabetes ResearchQ26841822
P1476titleGDF-15 as a Target and Biomarker for Diabetes and Cardiovascular Diseases: A Translational Prospective
P478volume2015

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