Higher-order interactions bridge the nitric oxide receptor and catalytic domains of soluble guanylate cyclase.

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Higher-order interactions bridge the nitric oxide receptor and catalytic domains of soluble guanylate cyclase. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PNAS..110.6777U
P356DOI10.1073/PNAS.1301934110
P932PMC publication ID3637750
P698PubMed publication ID23572573
P5875ResearchGate publication ID236189153

P50authorEric UnderbakkeQ77461679
P2093author name stringMichael A Marletta
Anthony T Iavarone
P2860cites workNO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potentialQ24656131
Two-metal-Ion catalysis in adenylyl cyclaseQ27619224
NO and CO differentially activate soluble guanylyl cyclase via a heme pivot-bend mechanismQ27641107
PAS-mediated Dimerization of Soluble Guanylyl Cyclase Revealed by Signal Transduction Histidine Kinase Domain Crystal StructureQ27649070
Structural basis of GC-1 selectivity for thyroid hormone receptor isoformsQ27649744
The crystal structure of the catalytic domain of a eukaryotic guanylate cyclaseQ27652454
A structural basis for H-NOX signaling in Shewanella oneidensis by trapping a histidine kinase inhibitory conformationQ27658207
Crystal structure of the signaling helix coiled-coil domain of the β1 subunit of the soluble guanylyl cyclaseQ27659219
Structure of cinaciguat (BAY 58-2667) bound to Nostoc H-NOX domain reveals insights into heme-mimetic activation of the soluble guanylyl cyclaseQ27661554
Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaSQ27748762
Hydrogen exchange mass spectrometry for the analysis of protein dynamicsQ28275804
Identification of residues in the heme domain of soluble guanylyl cyclase that are important for basal and stimulated catalytic activityQ28477878
Dissociation of nitric oxide from soluble guanylate cyclase and heme-nitric oxide/oxygen binding domain constructsQ28580525
Semi-automated data processing of hydrogen exchange mass spectra using HX-ExpressQ31056778
Structure, mechanism, and regulation of mammalian adenylyl cyclaseQ33540896
Fluorescent fusion proteins of soluble guanylyl cyclase indicate proximity of the heme nitric oxide domain and catalytic domainQ33640041
Endogenous nitric oxide synthesis: biological functions and pathophysiologyQ33814359
Guanylyl cyclases and signaling by cyclic GMP.Q33917038
HDX workbench: software for the analysis of H/D exchange MS dataQ34301944
Achieving reliability and high accuracy in automated protein docking: ClusPro, PIPER, SDU, and stability analysis in CAPRI rounds 13-19Q34522304
Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary diseaseQ35010064
Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactionsQ35040616
ClusPro: a fully automated algorithm for protein-protein dockingQ35554797
Fatal gastrointestinal obstruction and hypertension in mice lacking nitric oxide-sensitive guanylyl cyclaseQ35778348
Aspartate 102 in the heme domain of soluble guanylyl cyclase has a key role in NO activationQ35855521
Nitric oxide-sensitive guanylyl cyclase: structure and regulationQ35863606
Hydrogen exchange and mass spectrometry: A historical perspectiveQ36550545
Characterization of functional heme domains from soluble guanylate cyclaseQ36947015
Concepts of neural nitric oxide-mediated transmissionQ37029494
Versatility of signal transduction encoded in dimeric adenylyl cyclasesQ37340766
Structure and regulation of soluble guanylate cyclaseQ37992160
Expression and characterization of the catalytic domains of soluble guanylate cyclase: interaction with the heme domainQ39369792
Dimerization region of soluble guanylate cyclase characterized by bimolecular fluorescence complementation in vivo.Q51795151
Localization of the heme binding region in soluble guanylate cyclaseQ73940521
P433issue17
P407language of work or nameEnglishQ1860
P1104number of pages6
P304page(s)6777-6782
P577publication date2013-04-09
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleHigher-order interactions bridge the nitric oxide receptor and catalytic domains of soluble guanylate cyclase
P478volume110

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cites work (P2860)
Q38733562A structural basis for the regulation of an H-NOX-associated cyclic-di-GMP synthase/phosphodiesterase enzyme by nitric oxide-bound H-NOX.
Q83227485Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy
Q34870033Applications of hydrogen/deuterium exchange MS from 2012 to 2014.
Q46834683Conformational changes involved in sGC activation
Q45060738Cytochrome b5 Reductase 3 Modulates Soluble Guanylate Cyclase Redox State and cGMP Signaling
Q64274764Dynamic Characterization of the Human Heme Nitric Oxide/Oxygen (HNOX) Domain under the Influence of Diatomic Gaseous Ligands
Q42511668Guanylyl cyclase sensitivity to nitric oxide is protected by a thiol oxidation-driven interaction with thioredoxin-1.
Q36065122Heat Shock Protein 90 Associates with the Per-Arnt-Sim Domain of Heme-free Soluble Guanylate Cyclase: IMplications for Enzyme Maturation
Q40993195Hydrogen-Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling
Q27682500Interfacial residues promote an optimal alignment of the catalytic center in human soluble guanylate cyclase: heterodimerization is required but not sufficient for activity
Q93122173Loss of smooth muscle CYB5R3 amplifies angiotensin II-induced hypertension by increasing sGC heme oxidation
Q35855381Mapping Soluble Guanylyl Cyclase and Protein Disulfide Isomerase Regions of Interaction
Q27021422New insights into the role of soluble guanylate cyclase in blood pressure regulation
Q38914823Nitric Oxide Regulation of H-NOX Signaling Pathways in Bacteria
Q41848414Nitric oxide activation of guanylate cyclase pushes the α1 signaling helix and the β1 heme-binding domain closer to the substrate-binding site.
Q34075870Nitric oxide and heat shock protein 90 activate soluble guanylate cyclase by driving rapid change in its subunit interactions and heme content.
Q37191780Nitric oxide synthase domain interfaces regulate electron transfer and calmodulin activation
Q37727207Nitric oxide-induced conformational changes in soluble guanylate cyclase
Q38151386Nitric oxide-sensing H-NOX proteins govern bacterial communal behavior
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Q96302505Probing the Structural Dynamics of the Catalytic Domain of Human Soluble Guanylate Cyclase
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Q38777323Regulation of sGC via hsp90, Cellular Heme, sGC Agonists, and NO: New Pathways and Clinical Perspectives
Q37697630Regulation of soluble guanylate cyclase by matricellular thrombospondins: implications for blood flow.
Q37612777Single-particle EM reveals the higher-order domain architecture of soluble guanylate cyclase
Q34407649Structural insights into the role of iron-histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins
Q38894826Structure and Activation of Soluble Guanylyl Cyclase, the Nitric Oxide Sensor
Q55436230Structure/function of the soluble guanylyl cyclase catalytic domain.
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Q37557818YC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit.
Q38220091cGMP: transition from bench to bedside: a report of the 6th International Conference on cGMP Generators, Effectors and Therapeutic Implications

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