Enhanced GABA Transmission Drives Bradykinesia Following Loss of Dopamine D2 Receptor Signaling.

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Enhanced GABA Transmission Drives Bradykinesia Following Loss of Dopamine D2 Receptor Signaling. is …
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scholarly articleQ13442814

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P356DOI10.1016/J.NEURON.2016.04.040
P932PMC publication ID4882167
P698PubMed publication ID27196975

P50authorAlexxai V KravitzQ56867122
Veronica A AlvarezQ56939277
Danielle M FriendQ61312639
Alanna R KaplanQ61943873
P2093author name stringJung Hoon Shin
Marcelo Rubinstein
Julia C Lemos
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Mesolimbicocortical dopamine terminal fields are necessary for normal locomotor and investigatory exploration in ratsQ71327307
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Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviorsQ34093012
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Loss of Striatonigral GABAergic Presynaptic Inhibition Enables Motor Sensitization in Parkinsonian Mice.Q34492283
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Cortical stimulation evokes abnormal responses in the dopamine-depleted rat basal gangliaQ35110658
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A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior.Q35637848
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Dopamine Regulation of Lateral Inhibition between Striatal Neurons Gates the Stimulant Actions of CocaineQ36963501
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Glutamate and dopamine transmission from midbrain dopamine neurons share similar release properties but are differentially affected by cocaine.Q37603762
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Dopaminergic modulation of striatal networks in health and Parkinson's diseaseQ38233462
Rapid target-specific remodeling of fast-spiking inhibitory circuits after loss of dopamine.Q38366676
Depletion of dopamine in the striatum as an experimental model of Parkinsonism: direct effects and adaptive mechanismsQ40266245
D1 and D2 dopamine receptor modulation of sodium and potassium currents in rat neostriatal neuronsQ40621117
Differential regulation of motor control and response to dopaminergic drugs by D1R and D2R neurons in distinct dorsal striatum subregions.Q40885118
Upregulation of dopamine D2 receptors in the nucleus accumbens indirect pathway increases locomotion but does not reduce alcohol consumption.Q41595563
Adaptive mechanisms of striatal D1 and D2 dopamine receptors in response to a prolonged reserpine treatment in miceQ42064744
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Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease modelsQ42508054
Cortical slow oscillatory activity is reflected in the membrane potential and spike trains of striatal neurons in rats with chronic nigrostriatal lesions.Q42508172
Dopamine depletion causes fragmented clustering of neurons in the sensorimotor striatum: evidence of lasting reorganization of corticostriatal input.Q42525431
D2 dopamine receptors in striatal medium spiny neurons reduce L-type Ca2+ currents and excitability via a novel PLC[beta]1-IP3-calcineurin-signaling cascade.Q43513203
Motor behavioural changes after intracerebroventricular injection of 6-hydroxydopamine in the rat: an animal model of Parkinson's diseaseQ43564955
Short-term increase and long-term reversion of striatal cell activity after degeneration of the nigrostriatal dopamine systemQ43627070
In vivo extracellular recording of striatal neurons in the awake rat following unilateral 6-hydroxydopamine lesionsQ43718092
Heterosynaptic dopamine neurotransmission selects sets of corticostriatal terminalsQ44905912
D2 dopamine receptor-mediated modulation of voltage-dependent Na+ channels reduces autonomous activity in striatal cholinergic interneurons.Q45153496
Quantitative in situ hybridization evidence for differential regulation of proenkephalin and dopamine D2 receptor mRNA levels in the rat striatum: effects of unilateral intrastriatal injections of 6-hydroxydopamineQ45918593
D2R striatopallidal neurons inhibit both locomotor and drug reward processesQ46095429
P4510describes a project that usesImageJQ1659584
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectdopamineQ170304
P304page(s)824-838
P577publication date2016-05-01
P1433published inNeuronQ3338676
P1476titleEnhanced GABA Transmission Drives Bradykinesia Following Loss of Dopamine D2 Receptor Signaling
P478volume90

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