scholarly article | Q13442814 |
P356 | DOI | 10.1002/CBIC.201500239 |
P698 | PubMed publication ID | 26052818 |
P50 | author | Pei-Yuan Qian | Q52372051 |
P2093 | author name string | Ying Xu | |
Bin Wang | |||
Yongxin Li | |||
Guoqiang Zhu | |||
Liang Lu | |||
Jennifer Y H Lai | |||
Zhong-Rui Li | |||
Jianqiang Tang | |||
Xiyang Wu | |||
P2860 | cites work | Directed natural product biosynthesis gene cluster capture and expression in the model bacterium Bacillus subtilis | Q28552699 |
PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin | Q30764407 | ||
Two more pieces of the colibactin genotoxin puzzle from Escherichia coli show incorporation of an unusual 1-aminocyclopropanecarboxylic acid moiety | Q33365728 | ||
Thiazole and oxazole peptides: biosynthesis and molecular machinery | Q33636923 | ||
Comparative metabolomics and structural characterizations illuminate colibactin pathway-dependent small molecules. | Q33879227 | ||
Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells | Q33953217 | ||
The microbiome and cancer | Q35019302 | ||
Gut symbionts from distinct hosts exhibit genotoxic activity via divergent colibactin biosynthesis pathways. | Q35024032 | ||
The colibactin warhead crosslinks DNA. | Q35844576 | ||
Bleomycins: towards better therapeutics | Q36026763 | ||
Pyridin-2(1H)-ones: a promising class of HIV-1 non-nucleoside reverse transcriptase inhibitors | Q36810076 | ||
Intestinal inflammation targets cancer-inducing activity of the microbiota. | Q36819342 | ||
Genetic structure and distribution of the colibactin genomic island among members of the family Enterobacteriaceae. | Q37410263 | ||
Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A. | Q37571513 | ||
A natural prodrug activation mechanism in the biosynthesis of nonribosomal peptides. | Q38172793 | ||
Practical and efficient synthesis of pyrano[3,2-c]pyridone, pyrano[4,3-b]pyran and their hybrids with nucleoside as potential antiviral and antileishmanial agents | Q39753559 | ||
Escherichia coli induces DNA double-strand breaks in eukaryotic cells. | Q40244785 | ||
The genus Pseudovibrio contains metabolically versatile bacteria adapted for symbiosis | Q41890619 | ||
Heterologous production of albicidin: a promising approach to overproducing and characterizing this potent inhibitor of DNA gyrase. | Q41905085 | ||
Synthesis of 6-(2-thienyl)purine nucleoside derivatives that form unnatural base pairs with pyridin-2-one nucleosides | Q43713833 | ||
In vivo evidence for a prodrug activation mechanism during colibactin maturation. | Q44140961 | ||
A prodrug resistance mechanism is involved in colibactin biosynthesis and cytotoxicity | Q45678137 | ||
The gyrase inhibitor albicidin consists of p-aminobenzoic acids and cyanoalanine. | Q48234455 | ||
The genotoxin colibactin exacerbates lymphopenia and decreases survival rate in mice infected with septicemic Escherichia coli. | Q53068393 | ||
A natural prodrug activation mechanism in nonribosomal peptide synthesis. | Q53218701 | ||
Isolation of a metabolite from the pks island provides insights into colibactin biosynthesis and activity. | Q54272417 | ||
Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype. | Q54292519 | ||
P433 | issue | 12 | |
P921 | main subject | Escherichia coli | Q25419 |
colibactin | Q66363675 | ||
Precolibactin C | Q77376283 | ||
Precolibactin B | Q77483129 | ||
(R)-N1-((S)-7-((1-acetylcyclopropyl)amino)-5,7-dioxoheptan-2-yl)-2-tetradecanamidosuccinamide | Q105224209 | ||
P304 | page(s) | 1715-1719 | |
P577 | publication date | 2015-06-26 | |
P1433 | published in | ChemBioChem | Q634395 |
P1476 | title | Critical Intermediates Reveal New Biosynthetic Events in the Enigmatic Colibactin Pathway | |
P478 | volume | 16 |
Q46773646 | A Mechanistic Model for Colibactin-Induced Genotoxicity. |
Q54250718 | Characterization of Polyketide Synthase Machinery from the pks Island Facilitates Isolation of a Candidate Precolibactin. |
Q36219549 | ClbM is a versatile, cation-promiscuous MATE transporter found in the colibactin biosynthetic gene cluster. |
Q48349705 | ClbS Is a Cyclopropane Hydrolase That Confers Colibactin Resistance. |
Q57812436 | Clone of Plipastatin Biosynthesis Gene Cluster by Transformation-associated Recombination Technique and High Efficient Expression in Model Organism Bacillus subtilis |
Q47263315 | Colibactin assembly line enzymes use S-adenosylmethionine to build a cyclopropane ring. |
Q85631345 | Colibactin biosynthesis and biological activity depend on the rare aminomalonyl polyketide precursor |
Q52593550 | Colibactin: More Than a New Bacterial Toxin. |
Q34495096 | Colibactin: understanding an elusive gut bacterial genotoxin |
Q37309140 | Convergent and Modular Synthesis of Candidate Precolibactins. Structural Revision of Precolibactin A. |
Q38604510 | Direct Capture Technologies for Genomics-Guided Discovery of Natural Products |
Q36108894 | Divergent biosynthesis yields a cytotoxic aminomalonate-containing precolibactin |
Q48190463 | Domain-Targeted Metabolomics Delineates the Heterocycle Assembly Steps of Colibactin Biosynthesis |
Q101566484 | Employing chemical synthesis to study the structure and function of colibactin, a "dark matter" metabolite |
Q90939885 | Heterologous expression of bacterial natural product biosynthetic pathways |
Q41463199 | Identification of Secondary Metabolite Gene Clusters in the Pseudovibrio Genus Reveals Encouraging Biosynthetic Potential toward the Production of Novel Bioactive Compounds |
Q115733418 | Isolation of New Colibactin Metabolites from Wild-Type Escherichia coli and In Situ Trapping of a Mature Colibactin Derivative |
Q35803008 | Linking Biosynthetic Gene Clusters to their Metabolites via Pathway- Targeted Molecular Networking |
Q39443565 | MATE transport of the E. coli-derived genotoxin colibactin. |
Q90135219 | Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage |
Q58591398 | Model colibactins exhibit human cell genotoxicity in the absence of host bacteria |
Q48286824 | Molecular Basis of Gut Microbiome-Associated Colorectal Cancer: A Synthetic Perspective. |
Q36340566 | Natural product discovery from the human microbiome. |
Q36200942 | Natural products as mediators of disease. |
Q38727321 | On-line enzymatic tailoring of polyketides and peptides in thiotemplate systems |
Q95359278 | Photoactivated Colibactin Probes Induce Cellular DNA Damage |
Q93099442 | Reactivity of an Unusual Amidase May Explain Colibactin's DNA Cross-Linking Activity |
Q91182894 | Refining and expanding nonribosomal peptide synthetase function and mechanism |
Q90739257 | Signaling Natural Products from Human Pathogenic Bacteria |
Q38605864 | Structure and Functional Analysis of ClbQ, an Unusual Intermediate-Releasing Thioesterase from the Colibactin Biosynthetic Pathway |
Q96298063 | Structure and bioactivity of colibactin |
Q66499217 | Structure elucidation of colibactin and its DNA cross-links |
Q90242856 | Synthesis and reactivity of precolibactin 886 |
Q98569359 | Synthesis of Colibactin Pyrrolidono[3,4-d]pyridones via Regioselective C(sp3)-H Activation |
Q38897671 | The Enterobacterial Genotoxins: Cytolethal Distending Toxin and Colibactin |
Q35694112 | The Microbes inside Us and the Race for Colibactin |
Q86596654 | The human gut bacterial genotoxin colibactin alkylates DNA |
Q38817999 | Transformation-associated recombination (TAR) cloning for genomics studies and synthetic biology |
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