Characterization of Polyketide Synthase Machinery from the pks Island Facilitates Isolation of a Candidate Precolibactin.

scientific article

Characterization of Polyketide Synthase Machinery from the pks Island Facilitates Isolation of a Candidate Precolibactin. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/ACSCHEMBIO.6B00014
P698PubMed publication ID26890481

P50authorLi ZhaQ87785303
Matthew R. WilsonQ91595149
P2093author name stringEmily P Balskus
Carolyn A Brotherton
P2860cites workCritical Intermediates Reveal New Biosynthetic Events in the Enigmatic Colibactin PathwayQ30967654
Bithiazole metabolites from the myxobacterium Myxococcus fulvusQ40165181
P433issue5
P304page(s)1287-1295
P577publication date2016-03-01
P1433published inACS Chemical BiologyQ165583
P1476titleCharacterization of Polyketide Synthase Machinery from the pks Island Facilitates Isolation of a Candidate Precolibactin.
P478volume11

Reverse relations

cites work (P2860)
Q46773646A Mechanistic Model for Colibactin-Induced Genotoxicity.
Q92624751An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters
Q97568133ClbR Is the Key Transcriptional Activator of Colibactin Gene Expression in Escherichia coli
Q48349705ClbS Is a Cyclopropane Hydrolase That Confers Colibactin Resistance.
Q96127688Colibactin DNA-damage signature indicates mutational impact in colorectal cancer
Q47263315Colibactin assembly line enzymes use S-adenosylmethionine to build a cyclopropane ring.
Q52593550Colibactin: More Than a New Bacterial Toxin.
Q37309140Convergent and Modular Synthesis of Candidate Precolibactins. Structural Revision of Precolibactin A.
Q36108894Divergent biosynthesis yields a cytotoxic aminomalonate-containing precolibactin
Q48190463Domain-Targeted Metabolomics Delineates the Heterocycle Assembly Steps of Colibactin Biosynthesis
Q93363943Extender Unit Promiscuity and Orthogonal Protein Interactions of an Aminomalonyl-ACP Utilizing Trans-Acyltransferase from Zwittermicin Biosynthesis
Q92559319Genotoxic Escherichia coli Strains Encoding Colibactin, Cytolethal Distending Toxin, and Cytotoxic Necrotizing Factor in Laboratory Rats
Q92420554Intestinal colonization of genotoxic Escherichia coli strains encoding colibactin and cytotoxic necrotizing factor in small mammal pets
Q90135219Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage
Q58591398Model colibactins exhibit human cell genotoxicity in the absence of host bacteria
Q48286824Molecular Basis of Gut Microbiome-Associated Colorectal Cancer: A Synthetic Perspective.
Q36340566Natural product discovery from the human microbiome.
Q36200942Natural products as mediators of disease.
Q90739257Signaling Natural Products from Human Pathogenic Bacteria
Q38605864Structure and Functional Analysis of ClbQ, an Unusual Intermediate-Releasing Thioesterase from the Colibactin Biosynthetic Pathway
Q47579285Structure and function of polyketide biosynthetic enzymes: various strategies for production of structurally diverse polyketides
Q66499217Structure elucidation of colibactin and its DNA cross-links
Q90242856Synthesis and reactivity of precolibactin 886
Q90440303The Polyamine Spermidine Modulates the Production of the Bacterial Genotoxin Colibactin
Q86596654The human gut bacterial genotoxin colibactin alkylates DNA

Search more.