| scholarly article | Q13442814 |
| P50 | author | Alan Fairlamb | Q4706598 |
| Jon Clardy | Q16106217 | ||
| Deuan C Jones | Q117274721 | ||
| P2093 | author name string | Derek C Martyn | |
| P2860 | cites work | Substrate interactions between trypanothione reductase and N1-glutathionylspermidine disulphide at 0.28-nm resolution | Q27732141 |
| Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress | Q28144631 | ||
| Metabolism and functions of trypanothione in the Kinetoplastida | Q33972467 | ||
| Trypanothione Reductase from Leishmania donovani. Purification, Characterisation and Inhibition by Trivalent Antimonials | Q34058179 | ||
| Site-directed mutagenesis of the redox-active cysteines of Trypanosoma cruzi trypanothione reductase. | Q38915055 | ||
| The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro | Q39416311 | ||
| Ellman's-reagent-mediated regeneration of trypanothione in situ: substrate-economical microplate and time-dependent inhibition assays for trypanothione reductase | Q41790538 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | high-throughput screening | Q626251 |
| P304 | page(s) | 1280-1283 | |
| P577 | publication date | 2006-12-09 | |
| P1433 | published in | Bioorganic & Medicinal Chemistry Letters | Q2709483 |
| P1476 | title | High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity | |
| P478 | volume | 17 |
| Q30883740 | A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427. |
| Q45213048 | A new approach for potential drug target discovery through in silico metabolic pathway analysis using Trypanosoma cruzi genome information |
| Q28473648 | A target-based high throughput screen yields Trypanosoma brucei hexokinase small molecule inhibitors with antiparasitic activity |
| Q37333136 | Antiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives |
| Q27657406 | Comparative structural, kinetic and inhibitor studies of Trypanosoma brucei trypanothione reductase with T. cruzi |
| Q42163449 | Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery. |
| Q42058134 | High throughput screening against the peroxidase cascade of African trypanosomes identifies antiparasitic compounds that inactivate tryparedoxin |
| Q60312595 | Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening |
| Q33474992 | Improved tricyclic inhibitors of trypanothione reductase by screening and chemical synthesis |
| Q33393885 | Inhibitors of tubulin assembly identified through screening a compound library |
| Q30897674 | Investigation of trypanothione reductase as a drug target in Trypanosoma brucei |
| Q28474272 | Leishmanicidal metabolites from Cochliobolus sp., an endophytic fungus isolated from Piptadenia adiantoides (Fabaceae) |
| Q33309109 | Lessons learnt from assembling screening libraries for drug discovery for neglected diseases |
| Q45927357 | Novel aryl β-aminocarbonyl derivatives as inhibitors of Trypanosoma cruzi trypanothione reductase: binding mode revised by docking and GRIND2-based 3D-QSAR procedures. |
| Q39769260 | Observations on screening-based research and some concerning trends in the literature |
| Q27011766 | Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis |
| Q58865487 | Relevance of Trypanothione Reductase Inhibitors on Trypanosoma cruzi Infection: A Systematic Review, Meta-Analysis, and In Silico Integrated Approach |
| Q34088830 | Synthesis and evaluation of 1-(1-(Benzo[b]thiophen-2-yl)cyclohexyl)piperidine (BTCP) analogues as inhibitors of trypanothione reductase |
| Q38974228 | Synthetic Medicinal Chemistry in Chagas' Disease: Compounds at The Final Stage of "Hit-To-Lead" Phase |
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