Excitability constraints on voltage-gated sodium channels

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Excitability constraints on voltage-gated sodium channels is …
instance of (P31):
scholarly articleQ13442814

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P8978DBLP publication IDjournals/ploscb/AngelinoB07
P356DOI10.1371/JOURNAL.PCBI.0030177
P8608Fatcat IDrelease_t4csv6ccizfvfn5pj242uc23p4
P932PMC publication ID1988852
P698PubMed publication ID17892320
P5875ResearchGate publication ID5952737

P50authorMichael P. BrennerQ57599255
P2093author name stringElaine Angelino
P2860cites workbeta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kineticsQ22253235
A quantitative description of membrane current and its application to conduction and excitation in nerveQ22337072
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Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytesQ24319636
Evolution of vertebrate voltage-gated ion channel alpha chains by sequential gene duplicationQ46707557
Role of auxiliary beta1-, beta2-, and beta3-subunits and their interaction with Na(v)1.8 voltage-gated sodium channelQ47392752
Gating and modulation of presumptive NaV1.9 channels in enteric and spinal sensory neuronsQ47664856
Na+ channels must deactivate to recover from inactivationQ48143852
Hyperpolarized shifts in the voltage dependence of fast inactivation of Nav1.4 and Nav1.5 in a rat model of critical illness myopathyQ48869141
The extracellular domain of the beta1 subunit is both necessary and sufficient for beta1-like modulation of sodium channel gatingQ48906398
Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulinQ51819137
Noninactivating voltage-gated sodium channels in severe myoclonic epilepsy of infancyQ24563329
Evolution and diversity of mammalian sodium channel genesQ28141226
Nomenclature of voltage-gated sodium channelsQ28141860
Functional effects of two voltage-gated sodium channel mutations that cause generalized epilepsy with febrile seizures plus type 2Q28188391
A sodium-channel mutation causes isolated cardiac conduction diseaseQ28203120
Molecular basis of an inherited epilepsyQ28207595
Evolution and tinkeringQ28276084
International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channelsQ28289125
The VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic HomeostasisQ29032115
Sodium channel genes and the evolution of diversity in communication signals of electric fishes: convergent molecular evolutionQ30498750
Cloning, distribution and functional analysis of the type III sodium channel from human brainQ31720612
Electrophysiological and pharmacological properties of the human brain type IIA Na+ channel expressed in a stable mammalian cell lineQ32045201
Binding specificity of sea anemone toxins to Nav 1.1-1.6 sodium channels: unexpected contributions from differences in the IV/S3-S4 outer loop.Q34323654
Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy.Q34350866
Distribution and functional characterization of human Nav1.3 splice variantsQ34435132
Optimality and evolutionary tuning of the expression level of a proteinQ34437723
Evolution of voltage-gated Na(+) channelsQ34572944
Differential modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by the local anesthetic lidocaineQ35047167
Voltage-sensor sodium channel mutations cause hypokalemic periodic paralysis type 2 by enhanced inactivation and reduced currentQ35208537
Sodium channel inactivation: molecular determinants and modulationQ36267779
Evolution and divergence of sodium channel genes in vertebrates.Q36317103
Resting potential-dependent regulation of the voltage sensitivity of sodium channel gating in rat skeletal muscle in vivoQ36493507
Short hairpin RNA-mediated selective knockdown of NaV1.8 tetrodotoxin-resistant voltage-gated sodium channel in dorsal root ganglion neuronsQ40367562
A novel mutation L619F in the cardiac Na+ channel SCN5A associated with long-QT syndrome (LQT3): a role for the I-II linker in inactivation gatingQ40658677
Veratridine block of rat skeletal muscle Nav1.4 sodium channels in the inner vestibuleQ40665411
Molecular cloning, distribution and functional analysis of the NA(V)1.6. Voltage-gated sodium channel from human brainQ40719915
Nav1.3 sodium channels: rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons.Q40788199
Coexpression with beta(1)-subunit modifies the kinetics and fatty acid block of hH1(alpha) Na(+) channelsQ40868070
Modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by protein kinase A and protein kinase C.Q41914888
Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neuronsQ42169958
Functional analysis of the mouse Scn8a sodium channel.Q42540512
Functional analysis of the rat I sodium channel in xenopus oocytes.Q42545515
Beta1-subunit modulates the Nav1.4 sodium channel by changing the surface chargeQ42678686
A phenylalanine residue at segment D3-S6 in Nav1.4 voltage-gated Na(+) channels is critical for pyrethroid action.Q43705784
Modifications of human cardiac sodium channel gating by UVA lightQ44139098
GTP-induced tetrodotoxin-resistant Na+ current regulates excitability in mouse and rat small diameter sensory neuronesQ44372230
Altered gating and local anesthetic block mediated by residues in the I-S6 and II-S6 transmembrane segments of voltage-dependent Na+ channelsQ44550653
Closing and inactivation potentiate the cocaethylene inhibition of cardiac sodium channels by distinct mechanismsQ44674258
Mechanism of spontaneous excitability in human embryonic stem cell derived cardiomyocytesQ44970476
PGE2 increases the tetrodotoxin-resistant Nav1.9 sodium current in mouse DRG neurons via G-proteinsQ45063836
State-dependent mibefradil block of Na+ channelsQ45161630
The adult rat brain beta 1 subunit modifies activation and inactivation gating of multiple sodium channel alpha subunits.Q45955131
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P921main subjectvoltageQ25428
P304page(s)1751-1760
P577publication date2007-09-01
P1433published inPLOS Computational BiologyQ2635829
P1476titleExcitability constraints on voltage-gated sodium channels
P478volume3

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cites work (P2860)
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Q40768702More gating charges are needed to open a Shaker K+ channel than are needed to open an rBIIA Na+ channel
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Q57159551Spike-Conducting Integrate-and-Fire Model
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Q35598390What is the most realistic single-compartment model of spike initiation?

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