scholarly article | Q13442814 |
review article | Q7318358 |
P6179 | Dimensions Publication ID | 1024280805 |
P356 | DOI | 10.1038/NRG2188 |
P698 | PubMed publication ID | 17909538 |
P5875 | ResearchGate publication ID | 5934610 |
P50 | author | Leonard P. Guarente | Q6525606 |
P2093 | author name string | Nicholas A Bishop | |
P2860 | cites work | Sir2-independent life span extension by calorie restriction in yeast | Q21146406 |
Increased life span due to calorie restriction in respiratory-deficient yeast | Q21563472 | ||
Positional cloning of the mouse obese gene and its human homologue | Q22251285 | ||
Extension of chronological life span in yeast by decreased TOR pathway signaling | Q24539948 | ||
Sir2 mediates longevity in the fly through a pathway related to calorie restriction | Q24560016 | ||
Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway | Q24643816 | ||
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake | Q24674863 | ||
A C. elegans mutant that lives twice as long as wild type | Q27861054 | ||
Sir2 blocks extreme life-span extension. | Q27931453 | ||
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae | Q27931494 | ||
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae | Q27933365 | ||
HST2 mediates SIR2-independent life-span extension by calorie restriction | Q27934847 | ||
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans | Q28131824 | ||
Genetic pathways that regulate ageing in model organisms | Q28138437 | ||
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein | Q28211215 | ||
Hypothalamic mTOR signaling regulates food intake | Q28239714 | ||
Obesity wars: molecular progress confronts an expanding epidemic | Q28240764 | ||
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus | Q28254114 | ||
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients | Q28282424 | ||
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production | Q28511652 | ||
Intracellular signalling. Key enzyme in leptin-induced anorexia | Q28573472 | ||
Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake | Q28576714 | ||
Central nervous system control of food intake | Q29547439 | ||
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans | Q29616003 | ||
The plasticity of aging: insights from long-lived mutants | Q29616584 | ||
Genetics: influence of TOR kinase on lifespan in C. elegans | Q29616619 | ||
Two neurons mediate diet-restriction-induced longevity in C. elegans | Q29617239 | ||
The genetics of caloric restriction in Caenorhabditis elegans | Q29617240 | ||
Oxidative stress, caloric restriction, and aging | Q29618229 | ||
Extrachromosomal rDNA circles--a cause of aging in yeast | Q29618308 | ||
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration | Q29618751 | ||
Role of brain insulin receptor in control of body weight and reproduction | Q47229086 | ||
Regulation of Drosophila life span by olfaction and food-derived odors | Q47813082 | ||
Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y. | Q48216333 | ||
Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast. | Q48422925 | ||
Lifespan extension in Caenorhabditis elegans by complete removal of food. | Q48425642 | ||
Life extension via dietary restriction is independent of the Ins/IGF-1 signalling pathway in Caenorhabditis elegans. | Q48581848 | ||
Axenic growth up-regulates mass-specific metabolic rate, stress resistance, and extends life span in Caenorhabditis elegans. | Q48606988 | ||
No reduction of metabolic rate in food restricted Caenorhabditis elegans. | Q48606997 | ||
Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity. | Q48691942 | ||
Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways. | Q52020196 | ||
SIR2 and aging--the exception that proves the rule. | Q52133625 | ||
Dietary restriction in long-lived dwarf flies. | Q52595511 | ||
Dwarf mice and the ageing process. | Q55066759 | ||
Molecular Biology of Aging | Q57175231 | ||
Increased life span due to calorie restriction in respiratory-deficient yeast | Q60550800 | ||
Control of larval development by chemosensory neurons in Caenorhabditis elegans | Q70121859 | ||
Role of NADH shuttle system in glucose-induced activation of mitochondrial metabolism and insulin secretion | Q78111807 | ||
Increase in activity during calorie restriction requires Sirt1 | Q81598148 | ||
Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction" | Q83896183 | ||
Role of leptin in the neuroendocrine response to fasting | Q29618866 | ||
Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease | Q30846057 | ||
Chemosensory neurons with overlapping functions direct chemotaxis to multiple chemicals in C. elegans | Q33239290 | ||
Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands | Q33863373 | ||
Regulation of C. elegans life-span by insulinlike signaling in the nervous system | Q33920458 | ||
Extending the lifespan of long-lived mice | Q34102936 | ||
How does calorie restriction work? | Q34175282 | ||
Calorie restriction extends yeast life span by lowering the level of NADH. | Q34289946 | ||
Mice lacking melanin-concentrating hormone are hypophagic and lean | Q34485506 | ||
Beneficial effects of intermittent fasting and caloric restriction on the cardiovascular and cerebrovascular systems | Q34555561 | ||
Transgenic mice with a reduced core body temperature have an increased life span | Q34578942 | ||
Involvement of Drosophila uncoupling protein 5 in metabolism and aging | Q34587977 | ||
Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction | Q34595363 | ||
Central insulin action in energy and glucose homeostasis | Q34698802 | ||
Neuroendocrine and pharmacological manipulations to assess how caloric restriction increases life span | Q34712080 | ||
Interpreting interactions between treatments that slow aging | Q35185565 | ||
Neuronal glucosensing: what do we know after 50 years? | Q35901650 | ||
Hypothalamic sensing of fatty acids | Q36108719 | ||
Dietary restriction in Drosophila. | Q36151293 | ||
Effects of food restriction on aging: separation of food intake and adiposity | Q36256019 | ||
Sirtuins in aging and age-related disease. | Q36549075 | ||
Genome-wide identification of conserved longevity genes in yeast and worms | Q36663334 | ||
The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extension | Q36737714 | ||
Dietary deprivation extends lifespan in Caenorhabditis elegans | Q36897755 | ||
Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess | Q37054514 | ||
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans | Q41711470 | ||
Regulation of lifespan by sensory perception in Caenorhabditis elegans | Q41711479 | ||
A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2. | Q41773950 | ||
Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span | Q44042875 | ||
Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia | Q44286336 | ||
Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels | Q44363939 | ||
Metabolic pathways that mediate inhibition of hypothalamic neurons by glucose. | Q44704973 | ||
PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans | Q44731575 | ||
Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease | Q45223637 | ||
Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan | Q46366442 | ||
Regulation of C. elegans longevity by specific gustatory and olfactory neurons | Q46621417 | ||
Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly. | Q46626387 | ||
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. | Q46752037 | ||
A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span | Q46780211 | ||
Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO. | Q47069302 | ||
P433 | issue | 11 | |
P921 | main subject | lifetime | Q22675021 |
P304 | page(s) | 835-844 | |
P577 | publication date | 2007-11-01 | |
P1433 | published in | Nature Reviews Genetics | Q1071824 |
P1476 | title | Genetic links between diet and lifespan: shared mechanisms from yeast to humans | |
P478 | volume | 8 |
Q34482634 | 2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging process |
Q37178403 | A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration |
Q37856372 | A longer and healthier life with TOR down-regulation: genetics and drugs |
Q38327781 | A meta-analysis of caloric restriction gene expression profiles to infer common signatures and regulatory mechanisms. |
Q37069115 | A network biology approach to aging in yeast |
Q41845415 | A new Schizosaccharomyces pombe chronological lifespan assay reveals that caloric restriction promotes efficient cell cycle exit and extends longevity. |
Q35080652 | A novel kinase regulates dietary restriction-mediated longevity in Caenorhabditis elegans |
Q28586675 | A nutrient-sensitive interaction between Sirt1 and HNF-1α regulates Crp expression |
Q37089841 | Adipose-immune interactions during obesity and caloric restriction: reciprocal mechanisms regulating immunity and health span |
Q37730140 | Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation |
Q24625804 | Age-related cognitive decline: can neural stem cells help us? |
Q42171700 | Aging well with a little wine and a good clock |
Q26829192 | Amino acid homeostasis and chronological longevity in Saccharomyces cerevisiae |
Q41970961 | An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast |
Q34408010 | Antagonistic functions of LMNA isoforms in energy expenditure and lifespan |
Q90293338 | At the Interface of Lifestyle, Behavior, and Circadian Rhythms: Metabolic Implications |
Q33841058 | Autophagic activity in thymus and liver during aging |
Q37349831 | Autophagy genes and ageing |
Q37669237 | BAF-1 mobility is regulated by environmental stresses |
Q34383703 | Bacterial quorum sensing and metabolic slowing in a cooperative population |
Q37322071 | Barriers to the Preclinical Development of Therapeutics that Target Aging Mechanisms |
Q34556553 | Between destiny and disease: genetics and molecular pathways of human central nervous system aging |
Q41447146 | Biology, physiology and gene expression of grasshopper Oedaleus asiaticus exposed to diet stress from plant secondary compounds. |
Q38183940 | Budding yeast as a model organism to study the effects of age. |
Q21145855 | Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator |
Q50603723 | Caenorhabditis elegans OSM-11 signaling regulates SKN-1/Nrf during embryonic development and adult longevity and stress response. |
Q37675476 | Caloric Restriction Is More Efficient than Physical Exercise to Protect from Cisplatin Nephrotoxicity via PPAR-Alpha Activation |
Q34554528 | Caloric restriction experience reprograms stress and orexigenic pathways and promotes binge eating |
Q36752287 | Caloric restriction favorably impacts metabolic and immune/inflammatory profiles in obese mice but curcumin/piperine consumption adds no further benefit |
Q60932865 | Caloric restriction is associated with preservation of muscle strength in experimental cancer cachexia |
Q30437337 | Calorie restriction reduces rDNA recombination independently of rDNA silencing |
Q27324606 | Carbon dioxide sensing modulates lifespan and physiology in Drosophila |
Q27303840 | Cardioprotective Signature of Short-Term Caloric Restriction |
Q28384232 | Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders |
Q35852652 | Circadian rhythms and memory formation: regulation by chromatin remodeling |
Q37699510 | Clock-Enhancing Small Molecules and Potential Applications in Chronic Diseases and Aging |
Q36977423 | Coenzyme Q10 supplementation rescues renal disease in Pdss2kd/kd mice with mutations in prenyl diphosphate synthase subunit 2 |
Q37419745 | Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf. |
Q33617224 | Could Sirt1-mediated epigenetic effects contribute to the longevity response to dietary restriction and be mimicked by other dietary interventions? |
Q30540268 | Counterbalance between BAG and URX neurons via guanylate cyclases controls lifespan homeostasis in C. elegans |
Q51828022 | Coupled with uncouplers: the curious case of lifespan. |
Q45375660 | Cricket body size is altered by systemic RNAi against insulin signaling components and epidermal growth factor receptor |
Q26765684 | Cross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and Disease |
Q35741345 | DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition |
Q24300074 | DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1 |
Q34575823 | Deacetylation of the DNA-binding domain regulates p53-mediated apoptosis |
Q37358580 | Decoding the epigenetic language of neuronal plasticity |
Q35377033 | Deteriorated stress response in stationary-phase yeast: Sir2 and Yap1 are essential for Hsf1 activation by heat shock and oxidative stress, respectively |
Q37164094 | Detoxification reactions: relevance to aging |
Q42375846 | Diet alters performance and transcription patterns in Oedaleus asiaticus (Orthoptera: Acrididae) grasshoppers |
Q38197486 | Diet and our genetic legacy in the recent anthropocene: a Darwinian perspective to nutritional health. |
Q64068206 | Dietary Stress From Plant Secondary Metabolites Contributes to Grasshopper (Oedaleus asiaticus) Migration or Plague by Regulating Insect Insulin-Like Signaling Pathway |
Q36608681 | Dietary composition regulates Drosophila mobility and cardiac physiology. |
Q90396206 | Dietary habits, lifestyle factors and neurodegenerative diseases |
Q35223605 | Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease |
Q21133517 | Dietary restriction depends on nutrient composition to extend chronological lifespan in budding yeast Saccharomyces cerevisiae |
Q42012328 | Direct and trans-generational responses to food deprivation during development in the Glanville fritillary butterfly |
Q33411289 | Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity |
Q34388488 | Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes |
Q33747656 | Distinct signature of altered homeostasis in aging rod photoreceptors: implications for retinal diseases |
Q34966735 | Does hypothalamic SIRT1 regulate aging? |
Q41218560 | Early telomerase inactivation accelerates aging independently of telomere length |
Q90469680 | Effects of Lycium barbarum Polysaccharides on Health and Aging of C. elegans Depend on daf-12/daf-16 |
Q64275727 | Effects of short-term fasting on cancer treatment |
Q28727464 | Energetics of life on the deep seafloor |
Q24336770 | Evidence that the gene encoding insulin degrading enzyme influences human lifespan |
Q37602354 | Expression of cellular protective proteins SIRT1, HSP70 and SOD2 correlates with age and is significantly higher in NK cells of the oldest seniors. |
Q39853669 | Extended longevity and survivorship during amino-acid starvation in a Drosophila Sir2 mutant heterozygote |
Q36048743 | Extending healthy ageing: nutrient sensitive pathway and centenarian population. |
Q47129995 | FOXO Transcriptional Factors and Long-Term Living |
Q24647408 | FOXO3A genotype is strongly associated with human longevity |
Q92068160 | Fibroblast growth factor 21 prolongs lifespan and improves stress tolerance in the silkworm, Bombyx mori |
Q38755577 | Fibroblast growth factor 21: a regulator of metabolic disease and health span |
Q28243647 | Fighting neurodegeneration with rapamycin: mechanistic insights |
Q34371090 | Fission yeast does not age under favorable conditions, but does so after stress. |
Q94672680 | Flavonoid-rich foods (FRF): A promising nutraceutical approach against lifespan-shortening diseases |
Q51358136 | Food cues do not modulate the neuroendocrine response to a prolonged fast in healthy men. |
Q37346388 | From heterochromatin islands to the NAD World: a hierarchical view of aging through the functions of mammalian Sirt1 and systemic NAD biosynthesis |
Q37231454 | Functional implications of Drosophila insulin-like peptides in metabolism, aging, and dietary restriction |
Q24615803 | Genome-environment interactions that modulate aging: powerful targets for drug discovery |
Q46870075 | Growth phase-dependent roles of Sir2 in oxidative stress resistance and chronological lifespan in yeast |
Q60928052 | Gut-A Nexus Between Dietary Restriction and Lifespan |
Q36217330 | Heat shock and caloric restriction have a synergistic effect on the heat shock response in a sir2.1-dependent manner in Caenorhabditis elegans |
Q36109403 | Heat shock factors: integrators of cell stress, development and lifespan. |
Q35826675 | Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1α/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice. |
Q37157342 | Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. |
Q35105750 | High-resolution profiling of stationary-phase survival reveals yeast longevity factors and their genetic interactions. |
Q27003901 | Hormesis in aging and neurodegeneration-a prodigy awaiting dissection |
Q34890607 | Hungry for life: How the arcuate nucleus and neuropeptide Y may play a critical role in mediating the benefits of calorie restriction |
Q37614501 | Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice. |
Q33635978 | Hypothalamic and dietary control of temperature-mediated longevity |
Q55374784 | Importance of Nutrients and Nutrient Metabolism on Human Health. |
Q37485742 | Increasing longevity through caloric restriction or rapamycin feeding in mammals: common mechanisms for common outcomes? |
Q27937541 | Independent and additive effects of glutamic acid and methionine on yeast longevity |
Q34978376 | Inferring the effective TOR-dependent network: a computational study in yeast |
Q35947382 | Inflammaging: disturbed interplay between autophagy and inflammasomes |
Q37317349 | Inhibition of thymic adipogenesis by caloric restriction is coupled with reduction in age-related thymic involution |
Q35582500 | Insulin and JNK: optimizing metabolic homeostasis and lifespan |
Q35907071 | Integrating physiological regulation with stem cell and tissue homeostasis |
Q36450391 | Interactions between oxygen homeostasis, food availability, and hydrogen sulfide signaling |
Q37306689 | JNK signaling in insulin-producing cells is required for adaptive responses to stress in Drosophila |
Q36032226 | Joining the dots: from chromatin remodeling to neuronal plasticity |
Q36196765 | Ketogenic diets, mitochondria, and neurological diseases |
Q40389669 | Life is short, if sweet |
Q39577594 | Lifespan extension by calorie restriction relies on the Sty1 MAP kinase stress pathway |
Q38196808 | Linking Peroxiredoxin and Vacuolar-ATPase Functions in Calorie Restriction-Mediated Life Span Extension. |
Q37746601 | Living on the edge: stress and activation of stress responses promote lifespan extension |
Q26773901 | Long live FOXO: unraveling the role of FOXO proteins in aging and longevity |
Q52311275 | Long-term Dietary Macronutrients and Hepatic Gene Expression in Aging Mice. |
Q35005409 | Mammalian sirtuins and energy metabolism |
Q28077338 | Mechanisms of aging-related proteinopathies in Caenorhabditis elegans |
Q35687287 | Mechanisms of brain aging regulation by insulin: implications for neurodegeneration in late-onset Alzheimer's disease |
Q33665807 | Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster |
Q34358832 | Melatonin regulates aging and neurodegeneration through energy metabolism, epigenetics, autophagy and circadian rhythm pathways |
Q35854516 | Metabolic actions of hypothalamic SIRT1 |
Q48491781 | Metabolic programming of sirtuin 1 (SIRT1) expression by moderate energy restriction during gestation in rats may be related to obesity susceptibility in later life. |
Q37069557 | Metabolic reconfiguration is a regulated response to oxidative stress. |
Q49060165 | Methionine and homocysteine modulate the rate of ROS generation of isolated mitochondria in vitro. |
Q34400878 | MicroRNAs mediate dietary-restriction-induced longevity through PHA-4/FOXA and SKN-1/Nrf transcription factors |
Q33572241 | Mitochondrial function as a determinant of life span |
Q38252544 | Molecular pathways of arterial aging |
Q30575087 | Molecular phenotyping of aging in single yeast cells using a novel microfluidic device |
Q34629085 | N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans |
Q27671007 | NMR Structure of Hsp12, a Protein Induced by and Required for Dietary Restriction-Induced Lifespan Extension in Yeast |
Q27932205 | NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast. |
Q37815214 | New insights from rodent models of fatty liver disease |
Q39303280 | Nicotinic acid-mediated activation of both membrane and nuclear receptors towards therapeutic glucocorticoid mimetics for treating multiple sclerosis |
Q37137596 | Optimal window of caloric restriction onset limits its beneficial impact on T-cell senescence in primates |
Q33410837 | Optimizing dietary restriction for genetic epistasis analysis and gene discovery in C. elegans |
Q36470021 | Peripheral Circadian Clocks Mediate Dietary Restriction-Dependent Changes in Lifespan and Fat Metabolism in Drosophila. |
Q64266760 | Plasma proteomic and autoantibody profiles reveal the proteomic characteristics involved in longevity families in Bama, China |
Q33921101 | Polyhydroxy fullerenes (fullerols or fullerenols): beneficial effects on growth and lifespan in diverse biological models |
Q47930345 | Positive selection has driven the evolution of the Drosophila insulin-like receptor (InR) at different timescales |
Q35844163 | Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes |
Q30975227 | Ppargamma2 is a key driver of longevity in the mouse |
Q51392997 | Pre-operative dietary restriction is feasible in live-kidney donors. |
Q37785711 | Protein homeostasis and aging in neurodegeneration |
Q34314089 | Reduced expression of alpha-1,2-mannosidase I extends lifespan in Drosophila melanogaster and Caenorhabditis elegans |
Q38922191 | Regulation of autophagy by mitochondrial phospholipids in health and diseases. |
Q33603933 | Regulation of autophagy by the p300 acetyltransferase |
Q33919955 | Resveratrol and food effects on lifespan and reproduction in the model crustacean Daphnia |
Q28478644 | Resveratrol inhibits protein translation in hepatic cells |
Q36289947 | Role of microRNA processing in adipose tissue in stress defense and longevity |
Q24630974 | SIRT1 Promotes the Central Adaptive Response to Diet Restriction through Activation of the Dorsomedial and Lateral Nuclei of the Hypothalamus |
Q26864929 | SIRT1 and SIRT2: emerging targets in neurodegeneration |
Q36479802 | SIRT1 and energy metabolism |
Q37246556 | SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer. |
Q33588790 | SIRT1 performs a balancing act on the tight-rope toward longevity |
Q34413384 | SKN-1/Nrf2 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of methylmercury toxicity |
Q64082008 | Serotonin receptor HTR6-mediated mTORC1 signaling regulates dietary restriction-induced memory enhancement |
Q21091205 | Short-term calorie restriction in male mice feminizes gene expression and alters key regulators of conserved aging regulatory pathways |
Q36141448 | Short-term dietary restriction and fasting precondition against ischemia reperfusion injury in mice |
Q28590330 | Similar environments but diverse fates: Responses of budding yeast to nutrient deprivation |
Q36809695 | Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. |
Q33915481 | Sirtuin chemical mechanisms |
Q35923139 | Sirtuins and their relevance to the kidney. |
Q36844727 | Sirtuins, Cell Senescence, and Vascular Aging |
Q33417863 | Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo |
Q37150530 | Stress Inducibility of SIRT1 and Its Role in Cytoprotection and Cancer |
Q35621941 | TOR in the immune system |
Q43460839 | Telomere length as a potential biomarker of coronary artery disease |
Q41630273 | The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan |
Q28611444 | The Mass-Longevity Triangle: Pareto Optimality and the Geometry of Life-History Trait Space |
Q34917651 | The NAD World: a new systemic regulatory network for metabolism and aging--Sirt1, systemic NAD biosynthesis, and their importance |
Q24597971 | The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control |
Q29616026 | The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance |
Q35103174 | The Regulation of Aging and Longevity: A New and Complex Role of p53. |
Q33602912 | The Synergistic Role of Light-Feeding Phase Relations on Entraining Robust Circadian Rhythms in the Periphery |
Q27318396 | The circadian clock coordinates ribosome biogenesis |
Q37720893 | The contribution of dietary restriction to extended longevity in the malaria vector Anopheles coluzzii |
Q51608796 | The effect of sex peptide and calorie intake on fecundity in female Drosophila melanogaster. |
Q35799993 | The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study |
Q35111862 | The epigenetic landscape of alcoholism |
Q34966717 | The implication of Sir2 in replicative aging and senescence in Saccharomyces cerevisiae |
Q37218280 | The insulin paradox: aging, proteotoxicity and neurodegeneration |
Q37371440 | The regulation of aging: does autophagy underlie longevity? |
Q37779889 | The role of genetic variants in human longevity |
Q33604034 | The role of mitochondrial uncoupling proteins in lifespan |
Q34974831 | The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation |
Q34306190 | The starvation hormone, fibroblast growth factor-21, extends lifespan in mice. |
Q37587829 | The ubiquitin proteasome system in Caenorhabditis elegans and its regulation |
Q37283454 | Therapeutic application of histone deacetylase inhibitors for central nervous system disorders |
Q38534988 | Thermosensation and longevity |
Q55034292 | Transcriptome Analysis of the Thymus in Short-Term Calorie-Restricted Mice Using RNA-seq. |
Q37203938 | Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation |
Q38950512 | UPS Activation in the Battle Against Aging and Aggregation-Related Diseases: An Extended Review |
Q92962709 | celsr1a is essential for tissue homeostasis and onset of aging phenotypes in the zebrafish |
Q42661962 | dSir2 and fly mobility |
Q35947394 | dSir2 deficiency in the fatbody, but not muscles, affects systemic insulin signaling, fat mobilization and starvation survival in flies |
Q33588749 | dSir2 mediates the increased spontaneous physical activity in flies on calorie restriction |
Q34217628 | hNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signaling |
Q33620956 | skn-1 is required for interneuron sensory integration and foraging behavior in Caenorhabditis elegans |
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