Genetic links between diet and lifespan: shared mechanisms from yeast to humans

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Genetic links between diet and lifespan: shared mechanisms from yeast to humans is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1024280805
P356DOI10.1038/NRG2188
P698PubMed publication ID17909538
P5875ResearchGate publication ID5934610

P50authorLeonard P. GuarenteQ6525606
P2093author name stringNicholas A Bishop
P2860cites workSir2-independent life span extension by calorie restriction in yeastQ21146406
Increased life span due to calorie restriction in respiratory-deficient yeastQ21563472
Positional cloning of the mouse obese gene and its human homologueQ22251285
Extension of chronological life span in yeast by decreased TOR pathway signalingQ24539948
Sir2 mediates longevity in the fly through a pathway related to calorie restrictionQ24560016
Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathwayQ24643816
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intakeQ24674863
A C. elegans mutant that lives twice as long as wild typeQ27861054
Sir2 blocks extreme life-span extension.Q27931453
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiaeQ27931494
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiaeQ27933365
HST2 mediates SIR2-independent life-span extension by calorie restrictionQ27934847
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegansQ28131824
Genetic pathways that regulate ageing in model organismsQ28138437
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate proteinQ28211215
Hypothalamic mTOR signaling regulates food intakeQ28239714
Obesity wars: molecular progress confronts an expanding epidemicQ28240764
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamusQ28254114
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrientsQ28282424
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone productionQ28511652
Intracellular signalling. Key enzyme in leptin-induced anorexiaQ28573472
Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intakeQ28576714
Central nervous system control of food intakeQ29547439
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegansQ29616003
The plasticity of aging: insights from long-lived mutantsQ29616584
Genetics: influence of TOR kinase on lifespan in C. elegansQ29616619
Two neurons mediate diet-restriction-induced longevity in C. elegansQ29617239
The genetics of caloric restriction in Caenorhabditis elegansQ29617240
Oxidative stress, caloric restriction, and agingQ29618229
Extrachromosomal rDNA circles--a cause of aging in yeastQ29618308
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respirationQ29618751
Role of brain insulin receptor in control of body weight and reproductionQ47229086
Regulation of Drosophila life span by olfaction and food-derived odorsQ47813082
Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y.Q48216333
Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast.Q48422925
Lifespan extension in Caenorhabditis elegans by complete removal of food.Q48425642
Life extension via dietary restriction is independent of the Ins/IGF-1 signalling pathway in Caenorhabditis elegans.Q48581848
Axenic growth up-regulates mass-specific metabolic rate, stress resistance, and extends life span in Caenorhabditis elegans.Q48606988
No reduction of metabolic rate in food restricted Caenorhabditis elegans.Q48606997
Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.Q48691942
Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways.Q52020196
SIR2 and aging--the exception that proves the rule.Q52133625
Dietary restriction in long-lived dwarf flies.Q52595511
Dwarf mice and the ageing process.Q55066759
Molecular Biology of AgingQ57175231
Increased life span due to calorie restriction in respiratory-deficient yeastQ60550800
Control of larval development by chemosensory neurons in Caenorhabditis elegansQ70121859
Role of NADH shuttle system in glucose-induced activation of mitochondrial metabolism and insulin secretionQ78111807
Increase in activity during calorie restriction requires Sirt1Q81598148
Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction"Q83896183
Role of leptin in the neuroendocrine response to fastingQ29618866
Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's diseaseQ30846057
Chemosensory neurons with overlapping functions direct chemotaxis to multiple chemicals in C. elegansQ33239290
Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligandsQ33863373
Regulation of C. elegans life-span by insulinlike signaling in the nervous systemQ33920458
Extending the lifespan of long-lived miceQ34102936
How does calorie restriction work?Q34175282
Calorie restriction extends yeast life span by lowering the level of NADH.Q34289946
Mice lacking melanin-concentrating hormone are hypophagic and leanQ34485506
Beneficial effects of intermittent fasting and caloric restriction on the cardiovascular and cerebrovascular systemsQ34555561
Transgenic mice with a reduced core body temperature have an increased life spanQ34578942
Involvement of Drosophila uncoupling protein 5 in metabolism and agingQ34587977
Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restrictionQ34595363
Central insulin action in energy and glucose homeostasisQ34698802
Neuroendocrine and pharmacological manipulations to assess how caloric restriction increases life spanQ34712080
Interpreting interactions between treatments that slow agingQ35185565
Neuronal glucosensing: what do we know after 50 years?Q35901650
Hypothalamic sensing of fatty acidsQ36108719
Dietary restriction in Drosophila.Q36151293
Effects of food restriction on aging: separation of food intake and adiposityQ36256019
Sirtuins in aging and age-related disease.Q36549075
Genome-wide identification of conserved longevity genes in yeast and wormsQ36663334
The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extensionQ36737714
Dietary deprivation extends lifespan in Caenorhabditis elegansQ36897755
Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excessQ37054514
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegansQ41711470
Regulation of lifespan by sensory perception in Caenorhabditis elegansQ41711479
A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2.Q41773950
Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life spanQ44042875
Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexiaQ44286336
Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channelsQ44363939
Metabolic pathways that mediate inhibition of hypothalamic neurons by glucose.Q44704973
PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegansQ44731575
Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's diseaseQ45223637
Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespanQ46366442
Regulation of C. elegans longevity by specific gustatory and olfactory neuronsQ46621417
Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly.Q46626387
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS.Q46752037
A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life spanQ46780211
Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO.Q47069302
P433issue11
P921main subjectlifetimeQ22675021
P304page(s)835-844
P577publication date2007-11-01
P1433published inNature Reviews GeneticsQ1071824
P1476titleGenetic links between diet and lifespan: shared mechanisms from yeast to humans
P478volume8

Reverse relations

cites work (P2860)
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