scholarly article | Q13442814 |
P50 | author | Amelie Lupp | Q88477487 |
P2093 | author name string | Matthias Kohl | |
Sebastian N Stehr | |||
Markus H Gräler | |||
Ralf A Claus | |||
Andrea Schrepper | |||
Ha-Yeun Chung | |||
Anna S Kollmey | |||
Markus F Bläss | |||
P2860 | cites work | Acid sphingomyelinase deficient mice: a model of types A and B Niemann–Pick disease | Q24337312 |
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Tissue sulfhydryl groups | Q26778486 | ||
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Liver dysfunction and phosphatidylinositol-3-kinase signalling in early sepsis: experimental studies in rodent models of peritonitis | Q27307089 | ||
Exogenous and endogenous ceramides elicit volume-sensitive chloride current in ventricular myocytes | Q30493572 | ||
Hyperresponsiveness of mice deficient in plasma-secreted sphingomyelinase reveals its pivotal role in early phase of host response | Q30531999 | ||
Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice | Q30881683 | ||
Natural ceramide reverses Fas resistance of acid sphingomyelinase(-/-) hepatocytes. | Q31629166 | ||
Involvement of caspase 3- and 8-like proteases in ceramide-induced apoptosis of cardiomyocytes | Q33181090 | ||
Role of increased sphingomyelinase activity in apoptosis and organ failure of patients with severe sepsis | Q33341419 | ||
Efficacy of transthoracic echocardiography for diagnosing heart failure in septic shock | Q33654283 | ||
Calcium and mitochondrial metabolism in ceramide-induced cardiomyocyte death. | Q33986280 | ||
Ceramide as a second messenger: sticky solutions to sticky problems | Q34040269 | ||
Acidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesis | Q34086900 | ||
Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications | Q34117398 | ||
Acid sphingomyelinase serum activity predicts mortality in intensive care unit patients after systemic inflammation: a prospective cohort study | Q34482934 | ||
Ceramide: second messenger or modulator of membrane structure and dynamics? | Q34984863 | ||
Acid sphingomyelinase inhibitors normalize pulmonary ceramide and inflammation in cystic fibrosis | Q34994393 | ||
Ceramide in apoptosis: an overview and current perspectives | Q35047136 | ||
Alternative splicing of SMPD1 in human sepsis | Q35515785 | ||
Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis | Q35607603 | ||
Raft Domain Reorganization Driven by Short- and Long-Chain Ceramide: A Combined AFM and FCS Study | Q57366647 | ||
A fluorometric method for determination of oxidized and reduced glutathione in tissues | Q67805316 | ||
Central sympathoinhibition and peripheral neuronal uptake blockade after desipramine in rabbits | Q68295456 | ||
Cardiac troponins I and T are biological markers of left ventricular dysfunction in septic shock | Q73742930 | ||
Alterations by norepinephrine of cardiac sympathetic nerve terminal function and myocardial beta-adrenergic receptor sensitivity in the ferret: normalization by antioxidant vitamins | Q73954439 | ||
Quantification of sphingosine-1-phosphate and related sphingolipids by liquid chromatography coupled to tandem mass spectrometry | Q83974262 | ||
Characteristics of clinical sepsis reflected in a reliable and reproducible rodent sepsis model | Q84518230 | ||
Ceramide-mediated depression in cardiomyocyte contractility through PKC activation and modulation of myofilament protein phosphorylation | Q35634087 | ||
Diastolic dysfunction and mortality in severe sepsis and septic shock | Q35937776 | ||
Ceramide-enriched membrane domains | Q36286893 | ||
Mechanisms of sepsis-induced cardiac dysfunction | Q36799073 | ||
Ceramide is a cardiotoxin in lipotoxic cardiomyopathy | Q36870574 | ||
The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases | Q36879383 | ||
Erythropoietin attenuates cardiac dysfunction in experimental sepsis in mice via activation of the β-common receptor | Q36981847 | ||
Incidence, organ dysfunction and mortality in severe sepsis: a Spanish multicentre study. | Q37106056 | ||
Inhibition of sphingomyelin hydrolysis: targeting the lipid mediator ceramide as a key regulator of cellular fate | Q37515719 | ||
Cardiac dysfunction in severe sepsis and septic shock | Q37562775 | ||
Sepsis in old age: review of human and animal studies | Q37665355 | ||
Ceramide in Pseudomonas aeruginosa infections and cystic fibrosis | Q37760688 | ||
Ceramide: a simple sphingolipid with unique biophysical properties | Q38186915 | ||
Correlation of left ventricular systolic dysfunction determined by low ejection fraction and 30-day mortality in patients with severe sepsis and septic shock: a systematic review and meta-analysis | Q38205576 | ||
Myocardial depression in sepsis: from pathogenesis to clinical manifestations and treatment | Q38209176 | ||
The prognostic significance of troponin elevation in patients with sepsis: a meta-analysis | Q38277127 | ||
Presynaptic Alpha-Receptor Subsensitivity After Long-Term Antidepressant Treatment | Q40174097 | ||
New insights on the use of desipramine as an inhibitor for acid ceramidase | Q40244998 | ||
Acid sphingomyelinase promotes endothelial stress response in systemic inflammation and sepsis | Q40637739 | ||
Functions of ceramide in coordinating cellular responses to stress | Q41243489 | ||
Secretory sphingomyelinase is upregulated in chronic heart failure: a second messenger system of immune activation relates to body composition, muscular functional capacity, and peripheral blood flow | Q42165275 | ||
The challenge to verify ceramide's role of apoptosis induction in human cardiomyocytes--a pilot study | Q42213402 | ||
Sterol affinity for bilayer membranes is affected by their ceramide content and the ceramide chain length | Q43203609 | ||
Decreased rates of substrate oxidation ex vivo predict the onset of heart failure and contractile dysfunction in rats with pressure overload | Q43207763 | ||
Brain natriuretic peptide: A marker of myocardial dysfunction and prognosis during severe sepsis | Q43707142 | ||
Identification of a novel role for sphingolipid signaling in TNF alpha and ischemic preconditioning mediated cardioprotection | Q44022447 | ||
Differential pre- and postsynaptic effects of desipramine on cardiac sympathetic nerve terminals in RHF. | Q44182994 | ||
Profound but reversible myocardial depression in patients with septic shock | Q44250178 | ||
Desipramine attenuates loss of cardiac sympathetic neurotransmitters produced by congestive heart failure and NE infusion. | Q44288602 | ||
Plasma brain natriuretic peptide and troponin levels in severe sepsis and septic shock: relationships with systolic myocardial dysfunction and intensive care unit mortality | Q44691609 | ||
Role of ceramide in ischemic preconditioning | Q44864169 | ||
Cardiac troponin I predicts myocardial dysfunction and adverse outcome in septic shock | Q44907506 | ||
Volume-sensitive chloride channels (ICl,vol) mediate doxorubicin-induced apoptosis through apoptotic volume decrease in cardiomyocytes | Q45105221 | ||
Inhibition of ceramide de novo synthesis as a postischemic strategy to reduce myocardial reperfusion injury. | Q46608425 | ||
Ceramide-induced preconditioning involves reactive oxygen species | Q46722860 | ||
Cardiac sympathetic neuroprotective effect of desipramine in tachycardia-induced cardiomyopathy. | Q46743951 | ||
Role of lipid rafts in ceramide and nitric oxide signaling in the ischemic and preconditioned hearts | Q46842891 | ||
Inhibition of Acid Sphingomyelinase by Antidepressants Counteracts Stress-Induced Activation of P38-Kinase in Major Depression | Q47587515 | ||
Analysis of the lung pathology and alveolar macrophage function in the acid sphingomyelinase--deficient mouse model of Niemann-Pick disease | Q49240068 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | sepsis | Q183134 |
ceramides | Q424213 | ||
murine model | Q122890741 | ||
P577 | publication date | 2017-04-15 | |
P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
P1476 | title | Adjustment of Dysregulated Ceramide Metabolism in a Murine Model of Sepsis-Induced Cardiac Dysfunction | |
P478 | volume | 18 |
Q41993606 | Acid Sphingomyelinase Inhibition Prevents Development of Sepsis Sequelae in the Murine Liver |
Q57463140 | Acid Sphingomyelinase Inhibition Stabilizes Hepatic Ceramide Content and Improves Hepatic Biotransformation Capacity in a Murine Model of Polymicrobial Sepsis |
Q92889801 | Effect of sepsis on the action potential and cardiac serotonin response in rats |
Q89304884 | MiR-146b protect against sepsis induced mice myocardial injury through inhibition of Notch1 |
Q57491817 | γ-glutamylcysteine exhibits anti-inflammatory effects by increasing cellular glutathione level |
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