review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Arlan G. Richardson | Q21062344 |
P2093 | author name string | Adam B Salmon | |
Viviana I Pérez | |||
P2860 | cites work | Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans | Q21145012 |
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice | Q22242267 | ||
No increase in lifespan in Caenorhabditis elegans upon treatment with the superoxide dismutase mimetic EUK-8 | Q78772821 | ||
Does overexpression of Cu,Zn-SOD extend life span in Drosophila melanogaster? | Q78968772 | ||
High oxidative damage levels in the longest-living rodent, the naked mole-rat | Q79282502 | ||
Oxidation-resistant membrane phospholipids can explain longevity differences among the longest-living rodents and similarly-sized mice | Q79319551 | ||
Protein oxidation and aging | Q79336883 | ||
Disparate patterns of age-related changes in lipid peroxidation in long-lived naked mole-rats and shorter-lived mice | Q79385277 | ||
Overexpression of redox-active protein thioredoxin-1 prevents development of chronic pancreatitis in mice | Q80302426 | ||
Essential role of extracellular SOD in reparative neovascularization induced by hindlimb ischemia | Q80547915 | ||
Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice | Q80649565 | ||
Acceleration of diabetic renal injury in the superoxide dismutase knockout mouse: effects of tempol | Q80794376 | ||
Cultured renal epithelial cells from birds and mice: enhanced resistance of avian cells to oxidative stress and DNA damage | Q80806946 | ||
Skeletal muscle reperfusion injury is enhanced in extracellular superoxide dismutase knockout mouse | Q81546367 | ||
Reduction of age-associated pathology in old mice by overexpression of catalase in mitochondria | Q81932010 | ||
Characterization of transgenic mice that overexpress both copper zinc superoxide dismutase and catalase | Q83292772 | ||
Selecting the "right" mouse model for metabolic syndrome and type 2 diabetes research | Q84018470 | ||
Effects of dietary restriction and exercise on the age-related pathology of the rat | Q86630295 | ||
Articular aging and osteoarthrosis in dwarf mice | Q93733512 | ||
Cellular glutathione peroxidase protects mice against lethal oxidative stress induced by various doses of diquat | Q73189569 | ||
Partial deficiency of manganese superoxide dismutase exacerbates a transgenic mouse model of amyotrophic lateral sclerosis | Q73669583 | ||
Mice that overexpress Cu/Zn superoxide dismutase are resistant to allergen-induced changes in airway control | Q74113046 | ||
Properties and biological activities of thioredoxins | Q74150080 | ||
Transgenic models for the study of lung antioxidant defense: enhanced manganese-containing superoxide dismutase activity gives partial protection to B6C3 hybrid mice exposed to hyperoxia | Q74419927 | ||
Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice | Q77419196 | ||
High-quality life extension by the enzyme peptide methionine sulfoxide reductase | Q24530884 | ||
Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster | Q24542578 | ||
Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice | Q24544265 | ||
Extracellular superoxide dismutase in human tissues and human cell lines | Q24563402 | ||
Is the oxidative stress theory of aging dead? | Q24645213 | ||
Insulin resistance is a cellular antioxidant defense mechanism | Q24650976 | ||
The in vivo gene expression signature of oxidative stress | Q24653033 | ||
Methionine residues as endogenous antioxidants in proteins | Q24658367 | ||
Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase. | Q24671735 | ||
Aging: a theory based on free radical and radiation chemistry | Q27860549 | ||
Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo | Q27932583 | ||
Methionine sulfoxide reductase regulation of yeast lifespan reveals reactive oxygen species-dependent and -independent components of aging | Q27935539 | ||
Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae | Q27936862 | ||
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging | Q28191739 | ||
Trends in oxidative aging theories | Q28237122 | ||
The biologic clock: the mitochondria? | Q28249363 | ||
'Accelerated aging': a primrose path to insight? | Q28252271 | ||
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase | Q28284593 | ||
MnSOD deficiency has a differential effect on disease progression in two different ALS mutant mouse models | Q28291510 | ||
Age-related cochlear hair cell loss is enhanced in mice lacking copper/zinc superoxide dismutase | Q28504993 | ||
MnSOD deficiency increases endothelial dysfunction in ApoE-deficient mice | Q28506178 | ||
Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death | Q28506873 | ||
Increased sensitivity of homozygous Sod2 mutant mice to oxygen toxicity | Q28508044 | ||
Effects of variation in superoxide dismutases (SOD) on oxidative stress and apoptosis in lens epithelium | Q28508690 | ||
Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy | Q28508937 | ||
Phenotypes of mice lacking extracellular superoxide dismutase and copper- and zinc-containing superoxide dismutase | Q28509343 | ||
Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress | Q28509555 | ||
Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine | Q28510205 | ||
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury | Q28511628 | ||
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production | Q28511652 | ||
Cellular glutathione peroxidase deficiency and endothelial dysfunction | Q28513107 | ||
Mitochondrial disease in superoxide dismutase 2 mutant mice | Q28513450 | ||
Reduced fertility in female mice lacking copper-zinc superoxide dismutase | Q28584957 | ||
Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage | Q36459878 | ||
Age-related cardiac muscle sarcopenia: Combining experimental and mathematical modeling to identify mechanisms | Q36571044 | ||
Phenotypic rescue by a bovine transgene in a Cu/Zn superoxide dismutase-null mutant of Drosophila melanogaster | Q36646590 | ||
Mammals reduce methionine-S-sulfoxide with MsrA and are unable to reduce methionine-R-sulfoxide, and this function can be restored with a yeast reductase. | Q36940416 | ||
Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans | Q37010759 | ||
Genetics of atherosclerosis in murine models | Q37017734 | ||
Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat. | Q37117504 | ||
The overexpression of major antioxidant enzymes does not extend the lifespan of mice | Q37155784 | ||
Molecular inflammation: underpinnings of aging and age-related diseases | Q37197324 | ||
Retinal ion regulation in a mouse model of diabetic retinopathy: natural history and the effect of Cu/Zn superoxide dismutase overexpression. | Q37206608 | ||
Lipid peroxidation up-regulates BACE1 expression in vivo: a possible early event of amyloidogenesis in Alzheimer's disease | Q37275995 | ||
Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span | Q37355376 | ||
Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat. | Q37380117 | ||
Overexpression of Mn superoxide dismutase does not increase life span in mice | Q37381527 | ||
Skin-derived fibroblasts from long-lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone | Q37398644 | ||
Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity | Q37432488 | ||
Lifespan extension in genetically modified mice | Q37503535 | ||
The role of selenium peroxidases in the protection against oxidative damage of membranes | Q39673091 | ||
Enhanced diabetes-induced cataract in copper-zinc superoxide dismutase-null mice | Q39879189 | ||
Correlated resistance to glucose deprivation and cytotoxic agents in fibroblast cell lines from long-lived pituitary dwarf mice | Q40231160 | ||
Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress. | Q40460380 | ||
Extracellular superoxide dismutase attenuates lipopolysaccharide-induced neutrophilic inflammation | Q40534991 | ||
Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice | Q41725180 | ||
Suppression of atherogenesis by overexpression of glutathione peroxidase-4 in apolipoprotein E-deficient mice | Q41913870 | ||
Expression of bovine superoxide dismutase in Drosophila melanogaster augments resistance of oxidative stress | Q41951033 | ||
Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans | Q42247172 | ||
Fowl play and the price of petrel: long-living Procellariiformes have peroxidation-resistant membrane composition compared with short-living Galliformes | Q42276949 | ||
Low mitochondrial free radical production per unit O2 consumption can explain the simultaneous presence of high longevity and high aerobic metabolic rate in birds. | Q42488705 | ||
A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis. | Q42521789 | ||
The long lifespan of two bat species is correlated with resistance to protein oxidation and enhanced protein homeostasis | Q43102762 | ||
Changes in expression of antioxidant enzymes affect cell-mediated LDL oxidation and oxidized LDL-induced apoptosis in mouse aortic cells | Q43672896 | ||
Overexpression of copper/zinc-superoxide dismutase protects from kanamycin-induced hearing loss | Q43688650 | ||
Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu,Zn-SOD in mitochondria | Q43708597 | ||
Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis | Q43713944 | ||
Extracellular superoxide dismutase deficiency and atherosclerosis in mice | Q43738083 | ||
Strain-dependent high-level expression of a transgene for manganese superoxide dismutase is associated with growth retardation and decreased fertility | Q43762650 | ||
Genetic modification of prenatal lethality and dilated cardiomyopathy in Mn superoxide dismutase mutant mice | Q43777195 | ||
Glutathione peroxidase-1 deficiency leads to increased nuclear light scattering, membrane damage, and cataract formation in gene-knockout mice | Q43811182 | ||
Manganese superoxide dismutase deficiency exacerbates cerebral infarction after focal cerebral ischemia/reperfusion in mice: implications for the production and role of superoxide radicals | Q43901756 | ||
Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the Bad cell death signaling pathway. | Q44357321 | ||
Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism | Q44505357 | ||
Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span | Q44559269 | ||
Embryonic fibroblasts from Gpx4+/- mice: a novel model for studying the role of membrane peroxidation in biological processes | Q44627926 | ||
Catalase transgenic mice: characterization and sensitivity to oxidative stress | Q44753791 | ||
Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse | Q28585450 | ||
The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults | Q28587364 | ||
Glutathione-peroxidase-1 null muscle progenitor cells are globally defective | Q28587484 | ||
Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals | Q28587714 | ||
Cu/Zn SOD deficiency potentiates hearing loss and cochlear pathology in aged 129,CD-1 mice | Q28588882 | ||
Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: a model of age-related macular degeneration | Q28590177 | ||
Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene | Q28593572 | ||
Fibroblasts from naked mole-rats are resistant to multiple forms of cell injury, but sensitive to peroxide, ultraviolet light, and endoplasmic reticulum stress | Q28752254 | ||
Increased oxidative stress in obesity and its impact on metabolic syndrome | Q29012150 | ||
Extension of murine life span by overexpression of catalase targeted to mitochondria | Q29614546 | ||
The p66shc adaptor protein controls oxidative stress response and life span in mammals | Q29614553 | ||
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice | Q29616382 | ||
The free radical theory of aging matures | Q29618019 | ||
Oxidative stress, caloric restriction, and aging | Q29618229 | ||
Reactive oxygen species have a causal role in multiple forms of insulin resistance | Q29619831 | ||
A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation | Q29620430 | ||
Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease | Q30483386 | ||
Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease | Q30489145 | ||
Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis. | Q30491795 | ||
Long-lived ames dwarf mice are resistant to chemical stressors | Q30497373 | ||
A strategy for the ubiquitous overexpression of human catalase and CuZn superoxide dismutase genes in transgenic mice | Q30768763 | ||
Reduced free-radical production and extreme longevity in the little brown bat (Myotis lucifugus) versus two non-flying mammals | Q30827243 | ||
MsrB1 (methionine-R-sulfoxide reductase 1) knock-out mice: roles of MsrB1 in redox regulation and identification of a novel selenoprotein form | Q30850851 | ||
Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis | Q33208094 | ||
Mitochondrial oxidative stress causes hyperphosphorylation of tau. | Q33288260 | ||
Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life-span | Q33614307 | ||
Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging. | Q33806916 | ||
Fundamental aspects of reactive oxygen species, or what's the matter with oxygen? | Q33836182 | ||
Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity | Q33850583 | ||
Principles of animal use for gerontological research | Q33906163 | ||
Reactive oxygen species enhance insulin sensitivity | Q33941647 | ||
FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies | Q33957068 | ||
Methionine oxidation and aging | Q33984659 | ||
Effects of calorie restriction on polymicrobial peritonitis induced by cecum ligation and puncture in young C57BL/6 mice | Q33999522 | ||
The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake | Q34051250 | ||
Stress resistance and aging: influence of genes and nutrition. | Q34072427 | ||
Hormone-treated snell dwarf mice regain fertility but remain long lived and disease resistant | Q34076174 | ||
Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia | Q34111409 | ||
Prolonged longevity of hypopituitary dwarf mice | Q34132612 | ||
A Sod2 null mutation confers severely reduced adult life span in Drosophila | Q34287545 | ||
CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life | Q34366017 | ||
RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress | Q34415722 | ||
Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia | Q34430043 | ||
The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice | Q34463545 | ||
The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach | Q34468457 | ||
Molecular biology of glutathione peroxidase 4: from genomic structure to developmental expression and neural function. | Q34655209 | ||
Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis | Q34693231 | ||
Life and death: metabolic rate, membrane composition, and life span of animals. | Q34700154 | ||
Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide. | Q34751217 | ||
Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet. | Q34763602 | ||
Rate of generation of oxidative stress-related damage and animal longevity | Q34979739 | ||
Diabetes, oxidative stress, and antioxidants: a review | Q35077717 | ||
Behavioral and physiologic responses to caloric restriction in mice | Q35826663 | ||
The role of insulin and insulin-like growth factor-I in mammalian ageing | Q35840262 | ||
The role of oxidative damage and stress in aging. | Q35947926 | ||
Manganese superoxide dismutase protects mouse cortical neurons from chronic intermittent hypoxia-mediated oxidative damage | Q36178648 | ||
Long-lived Ames dwarf mice: Oxidative damage to mitochondrial DNA in heart and brain. | Q36269656 | ||
Studies of aging in ames dwarf mice: Effects of caloric restriction | Q36270099 | ||
Mitochondrial oxidant generation and oxidative damage in Ames dwarf and GH transgenic mice | Q36270598 | ||
A Measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegans | Q36416267 | ||
Altered oxidative stress response of the long-lived Snell dwarf mouse | Q44899540 | ||
Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans | Q44941245 | ||
Retardation of atherosclerosis by overexpression of catalase or both Cu/Zn-superoxide dismutase and catalase in mice lacking apolipoprotein E. | Q45140733 | ||
Superoxide dismutase 1 protects retinal cells from oxidative damage | Q45858830 | ||
Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity | Q46070812 | ||
SOD isoforms play no role in lifespan in ad lib or dietary restricted conditions, but mutational inactivation of SOD-1 reduces life extension by cold | Q46212369 | ||
Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms | Q46426971 | ||
Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat + maneb-induced Parkinson disease phenotype | Q46432912 | ||
Effects of simultaneous over-expression of Cu/ZnSOD and MnSOD on Drosophila melanogaster life span | Q46499340 | ||
Antioxidants do not explain the disparate longevity between mice and the longest-living rodent, the naked mole-rat | Q46640434 | ||
Age-related cataract progression in five mouse models for anti-oxidant protection or hormonal influence | Q46675293 | ||
Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice. | Q46706796 | ||
Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress | Q46829413 | ||
MsrA protects cardiac myocytes against hypoxia/reoxygenation induced cell death | Q46847971 | ||
Membrane phospholipid composition may contribute to exceptional longevity of the naked mole-rat (Heterocephalus glaber): a comparative study using shotgun lipidomics. | Q46889077 | ||
Attenuation of interstitial fibrosis and tubular apoptosis in db/db transgenic mice overexpressing catalase in renal proximal tubular cells | Q46918399 | ||
Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy | Q46966545 | ||
Calorie restriction inhibits the age-related dysregulation of the cytokines TNF-alpha and IL-6 in C3B10RF1 mice | Q46967933 | ||
Lack of the antioxidant glutathione peroxidase-1 does not increase atherosclerosis in C57BL/J6 mice fed a high-fat diet. | Q46968906 | ||
Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice. | Q47593587 | ||
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons | Q47991847 | ||
Elevated levels of brain-pathologies associated with neurodegenerative diseases in the methionine sulfoxide reductase A knockout mouse | Q48255624 | ||
Kleemeier award lecture: are there genes for aging? | Q48376887 | ||
Overexpression of human thioredoxin in transgenic mice controls oxidative stress and life span. | Q48486981 | ||
Hypertrophy of cerebral arterioles in mice deficient in expression of the gene for CuZn superoxide dismutase. | Q48504517 | ||
Glutathione peroxidase 4 protects cortical neurons from oxidative injury and amyloid toxicity. | Q48555925 | ||
Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats. | Q48685833 | ||
Response of lens epithelial cells to hydrogen peroxide stress and the protective effect of caloric restriction. | Q48726624 | ||
Effect of food restriction on life span and immune functions in long-lived Fischer-344 x Brown Norway F1 rats. | Q48772745 | ||
Differential MRI patterns of brain atrophy in double or single transgenic mice for APP and/or SOD. | Q49051051 | ||
Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mut | Q49157605 | ||
Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice. | Q50707608 | ||
Mnsod overexpression extends the yeast chronological (G(0)) life span but acts independently of Sir2p histone deacetylase to shorten the replicative life span of dividing cells. | Q51670074 | ||
Evidence that Ames dwarf mice age differently from their normal siblings in behavioral and learning and memory parameters. | Q51966561 | ||
Glutathione peroxidase protects mice from viral-induced myocarditis. | Q52531835 | ||
Simultaneous overexpression of copper- and zinc-containing superoxide dismutase and catalase retards age-related oxidative damage and increases metabolic potential in Drosophila melanogaster. | Q52539677 | ||
Assessment of growth parameters and life span of GHR/BP gene-disrupted mice. | Q52539802 | ||
Endogenous and exogenous thioredoxin 1 prevents goblet cell hyperplasia in a chronic antigen exposure asthma model. | Q53388199 | ||
Multiplex stress resistance in cells from long-lived dwarf mice. | Q53925947 | ||
Positive correlation between mammalian life span and cellular resistance to stress. | Q54098417 | ||
Thioredoxin protects against joint destruction in a murine arthritis model. | Q54603342 | ||
Dwarf mice and the ageing process. | Q55066759 | ||
Statistical methods for testing effects on “maximum lifespan” | Q57314349 | ||
Antioxidant defenses, longevity and ecophysiology of South American bats | Q58837421 | ||
Inactivation of Extracellular Superoxide Dismutase Contributes to the Development of High-Volume Hypertension | Q60722964 | ||
Extension of Life-Span with Superoxide Dismutase/Catalase Mimetics | Q62472542 | ||
Phospholipid hydroperoxide glutathione peroxidase is the 18-kDa selenoprotein expressed in human tumor cell lines | Q70141675 | ||
Evidence for extracellular superoxide dismutase as a mediator of hemorrhage-induced lung injury | Q73082035 | ||
Deficiency in superoxide dismutases shortens life span of yeast cells | Q73145979 | ||
Delayed occurrence of fatal neoplastic diseases in ames dwarf mice: correlation to extended longevity | Q73188869 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | oxidative stress | Q898814 |
P304 | page(s) | 642-655 | |
P577 | publication date | 2009-12-28 | |
P1433 | published in | Free Radical Biology and Medicine | Q5500023 |
P1476 | title | Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging? | |
P478 | volume | 48 |
Q36993446 | A botanical containing freeze dried açai pulp promotes healthy aging and reduces oxidative damage in sod1 knockdown flies |
Q34355548 | A comparative 'bottom up' proteomics strategy for the site-specific identification and quantification of protein modifications by electrophilic lipids. |
Q34254949 | A mitochondrial ATP synthase subunit interacts with TOR signaling to modulate protein homeostasis and lifespan in Drosophila |
Q38154565 | A review of oxidative stress in acute kidney injury: protective role of medicinal plants-derived antioxidants. |
Q35234482 | About the dangers, costs and benefits of living an aerobic lifestyle. |
Q60759379 | Accelerated sarcopenia in Cu/Zn superoxide dismutase knockout mice. |
Q37841938 | Age-related changes in skeletal muscle reactive oxygen species generation and adaptive responses to reactive oxygen species |
Q51456636 | Age-related changes in xanthine oxidase activity and lipid peroxidation, as well as in the correlation between both parameters, in plasma and several organs from female mice. |
Q44117096 | Ageing-induced decrease in cardiac mitochondrial function in healthy rats |
Q36644107 | Aging Increases Susceptibility to High Fat Diet-Induced Metabolic Syndrome in C57BL/6 Mice: Improvement in Glycemic and Lipid Profile after Antioxidant Therapy |
Q34341924 | Aging and energetics' 'Top 40' future research opportunities 2010-2013. |
Q36331234 | Aging studies in Drosophila melanogaster |
Q53335819 | Aging-associated changes in oxidative stress, cell proliferation, and apoptosis are prevented in the prostate of transgenic rats overexpressing regucalcin. |
Q35156879 | Amelioration of reproduction-associated oxidative stress in a viviparous insect is critical to prevent reproductive senescence |
Q92509993 | An Overview of Neuromuscular Junction Aging Findings in Human and Animal Studies |
Q60922943 | Anti-senescence effect and molecular mechanism of the major royal jelly proteins on human embryonic lung fibroblast (HFL-I) cell line |
Q36388008 | Apocynin suppression of NADPH oxidase reverses the aging process in mesenchymal stem cells to promote osteogenesis and increase bone mass |
Q38612112 | Aromatic Regions Govern the Recognition of NADPH Oxidase Inhibitors as Diapocynin and its Analogues |
Q38943225 | Associations of metabolic, inflammatory and oxidative stress markers with total morbidity and multi-morbidity in a large cohort of older German adults |
Q40231476 | Associations of self-reported smoking, cotinine levels and epigenetic smoking indicators with oxidative stress among older adults: a population-based study |
Q91790858 | Astaxanthin: A Potential Mitochondrial-Targeted Antioxidant Treatment in Diseases and with Aging |
Q38129325 | Atypical aging in Down syndrome |
Q37801925 | Autophagy, reactive oxygen species and the fate of mammalian cells |
Q39188257 | BZLF1 Attenuates Transmission of Inflammatory Paracrine Senescence in Epstein-Barr Virus-Infected Cells by Downregulating Tumor Necrosis Factor Alpha |
Q42514352 | Bacopa monnieri and L-deprenyl differentially enhance the activities of antioxidant enzymes and the expression of tyrosine hydroxylase and nerve growth factor via ERK 1/2 and NF-κB pathways in the spleen of female wistar rats |
Q26738696 | Beyond Diabetes: Does Obesity-Induced Oxidative Stress Drive the Aging Process? |
Q35870421 | Biological effects of pyrroloquinoline quinone on liver damage in Bmi-1 knockout mice |
Q48476281 | Boron attenuates malathion-induced oxidative stress and acetylcholinesterase inhibition in rats. |
Q37109486 | C-phycocyanin protects against low fertility by inhibiting reactive oxygen species in aging mice |
Q30503246 | Calcific aortic valve stenosis: methods, models, and mechanisms |
Q39437518 | Callogenesis and cell suspension establishment of tropical highland blackberry (Rubus adenotrichos Schltdl.) and its microscopic analysis. |
Q33954183 | Caloric restriction and the aging process: a critique |
Q38221517 | Causes and Consequences of Age-Related Changes in DNA Methylation: A Role for ROS? |
Q42810724 | Cellular stress responses, mitostress and carnitine insufficiencies as critical determinants in aging and neurodegenerative disorders: role of hormesis and vitagenes |
Q36369055 | Changes in Oxidative Stress and Inflammatory Biomarkers in Fragile Adults over Fifty Years of Age and in Elderly People Exclusively Fed Enteral Nutrition |
Q64230369 | Changes in Redox Signaling in the Skeletal Muscle with Aging |
Q46128862 | Cigarette smoking is associated with amplified age-related volume loss in subcortical brain regions |
Q34943665 | Comparative effect of Piper betle, Chlorella vulgaris and tocotrienol-rich fraction on antioxidant enzymes activity in cellular ageing of human diploid fibroblasts |
Q34402730 | Computational biology for ageing |
Q44583610 | Delay in oocyte aging in mice by the antioxidant N-acetyl-L-cysteine (NAC). |
Q41309055 | Different effects of accelerated development and enhanced growth on oxidative stress and telomere shortening in amphibian larvae. |
Q41587640 | Discovery of a novel epigenetic cancer marker related to the oxidative status of human blood |
Q22252371 | Down syndrome as a model of DNA polymerase beta haploinsufficiency and accelerated aging |
Q37539332 | Early life hormetic treatments decrease irradiation-induced oxidative damage, increase longevity, and enhance sexual performance during old age in the Caribbean fruit fly. |
Q36006987 | Effects of Flight on Gene Expression and Aging in the Honey Bee Brain and Flight Muscle |
Q37039462 | Effects of aluminum on the reduction of neural stem cells, proliferating cells, and differentiating neuroblasts in the dentate gyrus of D-galactose-treated mice via increasing oxidative stress |
Q49104040 | Effects of root and stem extracts of Asparagus cochinchinensis on biochemical indicators related to aging in the brain and liver of mice. |
Q38283435 | Environmental chemical exposure may contribute to uterine cancer development: studies with tetrabromobisphenol A. |
Q47362434 | Epigenetic factors Polycomb (Pc) and Suppressor of zeste (Su(z)2) negatively regulate longevity in Drosophila melanogaster. |
Q28604259 | Evidence for the free radical/oxidative stress theory of ageing from the CHANCES consortium: a meta-analysis of individual participant data |
Q36795194 | Exceptionally old mice are highly resistant to lipoxidation-derived molecular damage. |
Q38299330 | Exercise improves mitochondrial and redox-regulated stress responses in the elderly: better late than never! |
Q34577195 | Expansions of NK-like αβT cells with chronologic aging: novel lymphocyte effectors that compensate for functional deficits of conventional NK cells and T cells |
Q35785172 | Extension of Drosophila lifespan by Rosa damascena associated with an increased sensitivity to heat |
Q36889384 | FOXO3 gene variants and human aging: coding variants may not be key players |
Q35793084 | Fluorescent coumarin thiols measure biological redox couples |
Q36576374 | Gene expression changes in response to aging compared to heat stress, oxidative stress and ionizing radiation in Drosophila melanogaster |
Q35895826 | Healthy aging - insights from Drosophila |
Q34808934 | Hypothalamic microinflammation: a common basis of metabolic syndrome and aging |
Q35527157 | In vitro caloric restriction induces protective genes and functional rejuvenation in senescent SAMP8 astrocytes. |
Q37644832 | Increased oxidative stress response in granulocytes from older patients with a hip fracture may account for slow regeneration |
Q35289227 | Increased transsulfuration mediates longevity and dietary restriction in Drosophila |
Q33611049 | Insights into the biochemical defence and methylation of the solitary bee Osmia rufa L: A foundation for examining eusociality development. |
Q38840303 | Integrated High-Content Quantification of Intracellular ROS Levels and Mitochondrial Morphofunction |
Q39582010 | Intraperoxisomal redox balance in mammalian cells: oxidative stress and interorganellar cross-talk |
Q36053603 | Large-brained birds suffer less oxidative damage |
Q39680203 | Life-extending Dietary Restriction Reduces Oxidative Damage of Proteins in Grasshoppers but Does Not Alter Allocation of Ingested Nitrogen to Somatic Tissues |
Q37127776 | Life-extending ovariectomy in grasshoppers increases somatic storage, but dietary restriction with an equivalent feeding rate does not |
Q33689091 | Lifespan effects of simple and complex nutraceutical combinations fed isocalorically to mice |
Q39413014 | Lifestyle predictors of oxidant and antioxidant enzyme activities and total antioxidant capacity in healthy women: a cross-sectional study |
Q33696613 | Litter size manipulation in laboratory mice: an example of how proteomic analysis can uncover new mechanisms underlying the cost of reproduction. |
Q92969282 | Longitudinal Associations of Body Mass Index, Waist Circumference, and Waist-to-Hip Ratio with Biomarkers of Oxidative Stress in Older Adults: Results of a Large Cohort Study |
Q34072831 | Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality |
Q37369413 | Manipulating reproductive effort leads to changes in female reproductive scheduling but not oxidative stress |
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Q26783337 | Mechanisms of Muscle Denervation in Aging: Insights from a Mouse Model of Amyotrophic Lateral Sclerosis |
Q38405132 | Mechanisms of oxidative stress resistance in the brain: Lessons learned from hypoxia tolerant extremophilic vertebrates |
Q34385833 | Medicinal plants for renal injury prevention |
Q36068166 | Metallothionein and the biology of aging |
Q48002812 | Mice with heterozygous deficiency of manganese superoxide dismutase (SOD2) have a skin immune system with features of "inflamm-aging". |
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Q34665297 | Mitochondrial DNA damage and animal longevity: insights from comparative studies |
Q26799985 | Mitochondrial Oxidative Stress, Mitochondrial DNA Damage and Their Role in Age-Related Vascular Dysfunction |
Q33911069 | Mitochondrial changes in ageing Caenorhabditis elegans--what do we learn from superoxide dismutase knockouts? |
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Q28383638 | Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration |
Q37903182 | Molecular and structural antioxidant defenses against oxidative stress in animals |
Q26749241 | NPGPx (GPx7): a novel oxidative stress sensor/transmitter with multiple roles in redox homeostasis |
Q37154162 | Naturally high plasma glucose levels in mourning doves (Zenaida macroura) do not lead to high levels of reactive oxygen species in the vasculature |
Q34624910 | Neuronal calcium homeostasis and dysregulation |
Q36243410 | Nordihydroguaiaretic Acid Extends the Lifespan of Drosophila and Mice, Increases Mortality-Related Tumors and Hemorrhagic Diathesis, and Alters Energy Homeostasis in Mice. |
Q36238968 | Nutraceutical interventions for promoting healthy aging in invertebrate models |
Q35807099 | Nutraceuticals for geriatrics |
Q36240788 | Nutrient-dependent requirement for SOD1 in lifespan extension by protein restriction in Drosophila melanogaster |
Q38936629 | Nutrigenomics at the Interface of Aging, Lifespan, and Cancer Prevention |
Q47635239 | Obsolete ideas and logical confusions can be obstacles for biogerontology research |
Q37622395 | Ovarian aging-like phenotype in the hyperandrogenism-induced murine model of polycystic ovary |
Q60949465 | Oxidative Stress as Cause, Consequence, or Biomarker of Altered Female Reproduction and Development in the Space Environment |
Q37195821 | Oxidative damage and cellular defense mechanisms in sea urchin models of aging |
Q45419859 | Oxidative damage and plasma antioxidant capacity in relation to body size, age, male sexual traits and female reproductive performance in the collared flycatcher (Ficedula albicollis). |
Q37005075 | Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging. |
Q26853196 | Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models? |
Q63681998 | Oxidative stress and epigenetic mortality risk score: associations with all-cause mortality among elderly people |
Q35904697 | Oxidative stress and life histories: unresolved issues and current needs. |
Q34745222 | Oxidative stress and longevity in okinawa: an investigation of blood lipid peroxidation and tocopherol in okinawan centenarians |
Q38084435 | Oxidative stress and the ageing endocrine system |
Q38230280 | Oxidative stress in pregnancy and fertility pathologies |
Q38207007 | Oxidative stress in the etiology of age-associated decline in glucose metabolism |
Q39152460 | Oxidative stress markers and all-cause mortality at older age: a population-based cohort study |
Q26782125 | Oxidative stress, thyroid dysfunction & Down syndrome |
Q64935973 | Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview. |
Q35234072 | Pathways to aging: the mitochondrion at the intersection of biological and psychosocial sciences. |
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Q36927688 | Peroxisome degradation in mammals: mechanisms of action, recent advances, and perspectives |
Q41438914 | Phenotypes, antioxidant responses, and gene expression changes accompanying a sugar-only diet in Bactrocera dorsalis (Hendel) (Diptera: Tephritidae). |
Q50510778 | Polyphenols decreased liver NADPH oxidase activity, increased muscle mitochondrial biogenesis and decreased gastrocnemius age-dependent autophagy in aged rats. |
Q37944053 | Potential role of antioxidant food supplements, preservatives and colorants in the pathogenesis of allergy and asthma |
Q35086834 | Premature aging with impaired oxidative stress defense in mice lacking TR4. |
Q34343191 | Prolonged lifespan with enhanced exploratory behavior in mice overexpressing the oxidized nucleoside triphosphatase hMTH1. |
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Q37939948 | Redox balance in the aging microcirculation: new friends, new foes, and new clinical directions. |
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Q35673711 | Resistance to the Beneficial Metabolic Effects and Hepatic Antioxidant Defense Actions of Fibroblast Growth Factor 21 Treatment in Growth Hormone-Overexpressing Transgenic Mice. |
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Q96641760 | Rodent Model of Muscular Atrophy for Sarcopenia Study |
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Q38730906 | Role of reactive oxygen species in age-related neuromuscular deficits |
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Q34464696 | Stress activated protein kinase pathway modulates homologous recombination in fission yeast |
Q37267831 | Stress and stem cells |
Q38082744 | Study of antioxidative effects and anti-inflammatory effects in mice due to low-dose X-irradiation or radon inhalation |
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Q33760075 | The Protective Effect of N-Acetylcysteine on Ionizing Radiation Induced Ovarian Failure and Loss of Ovarian Reserve in Female Mouse |
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Q36528271 | The effect of resveratrol on lifespan depends on both gender and dietary nutrient composition in Drosophila melanogaster |
Q28392215 | The effects of oxidative stress on female reproduction: a review |
Q36298718 | The evolution of sex: A new hypothesis based on mitochondrial mutational erosion: Mitochondrial mutational erosion in ancestral eukaryotes would favor the evolution of sex, harnessing nuclear recombination to optimize compensatory nuclear coadaptati |
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Q57921401 | The peroxisome: an update on mysteries 2.0 |
Q41298557 | The role of oxidative stress in nervous system aging. |
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Q48887911 | Theanine intake improves the shortened lifespan, cognitive dysfunction and behavioural depression that are induced by chronic psychosocial stress in mice. |
Q36587651 | Time line of redox events in aging postmitotic cells |
Q61066509 | Transcripts encoding free radical scavengers in human granulosa cells from primordial and primary ovarian follicles |
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Q36161869 | Vitellogenin-RNAi and ovariectomy each increase lifespan, increase protein storage, and decrease feeding, but are not additive in grasshoppers. |
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Q55176338 | Young and Especially Senescent Endothelial Microvesicles Produce NADPH: The Fuel for Their Antioxidant Machinery. |
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