RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice

scientific article

RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/MT.2009.271
P932PMC publication ID2839291
P698PubMed publication ID19997090
P5875ResearchGate publication ID40483905

P50authorDan PeerQ43193344
P2093author name stringN Manjunath
Katsuyoshi Habiro
Premlata Shankar
Priti Kumar
Sang-Soo Kim
Yong-Guang Yang
Motomu Shimaoka
Sandesh Subramanya
Deshratan Asthana
Huaquan Wu
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Both memory and CD45RA+/CD62L+ naive CD4(+) T cells are infected in human immunodeficiency virus type 1-infected individualsQ33816825
Human immunodeficiency virus type 1 strains R5 and X4 induce different pathogenic effects in hu-PBL-SCID mice, depending on the state of activation/differentiation of human target cells at the time of primary infection.Q33816889
HIV entry inhibitors and their potential in HIV therapyQ34595921
Transvascular delivery of small interfering RNA to the central nervous system.Q34638044
Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophagesQ35149275
Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1.Q35676793
Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice.Q35784905
Lentiviral delivery of short hairpin RNAs protects CD4 T cells from multiple clades and primary isolates of HIVQ35847908
Stable reduction of CCR5 by RNAi through hematopoietic stem cell transplant in non-human primatesQ35928777
Activation of the mammalian immune system by siRNAs.Q36307323
RNAi as a treatment for HIV-1 infection.Q36455689
Interfering antiviral immunity: application, subversion, hope?Q36497229
HIV-1 infection and CD4 T cell depletion in the humanized Rag2-/-gamma c-/- (RAG-hu) mouse modelQ38905274
LFA-1 expression on target cells promotes human immunodeficiency virus type 1 infection and transmissionQ39601711
Statin compounds reduce human immunodeficiency virus type 1 replication by preventing the interaction between virion-associated host intercellular adhesion molecule 1 and its natural cell surface ligand LFA-1.Q40214644
The binding sites for competitive antagonistic, allosteric antagonistic, and agonistic antibodies to the I domain of integrin LFA-1.Q40517700
siRNA-directed inhibition of HIV-1 infectionQ40727988
Chemokine (C-C motif) receptor 5 entry inhibitors: new class of drugs for acquired immune deficiency syndromeQ43806067
Hyaluronan is a key component in cryoprotection and formulation of targeted unilamellar liposomesQ44428946
Loading mitomycin C inside long circulating hyaluronan targeted nano-liposomes increases its antitumor activity in three mice tumor modelsQ44706686
Physicochemical evaluation of a stability-driven approach to drug entrapment in regular and in surface-modified liposomesQ47619451
Asymmetric RNA duplexes mediate RNA interference in mammalian cells.Q53436494
Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNAQ81547115
Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptorsQ81772313
Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantationQ82252349
P433issue2
P921main subjectnanoparticleQ61231
P304page(s)370-376
P577publication date2009-12-08
P1433published inMolecular TherapyQ15762400
P1476titleRNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice
P478volume18

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