XBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis.

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XBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.0900953
P932PMC publication ID4053221
P698PubMed publication ID19710472
P5875ResearchGate publication ID26770450

P50authorHidde PloeghQ1617296
You-Me KimQ30503780
Annette M McGeheeQ55714855
Markus R. WenkQ90987707
P2093author name stringGuanghou Shui
Boyoun Park
Nicki Watson
Stephanie K Dougan
Chih-Chi Andrew Hu
Elizabeth J Klemm
P2860cites workMammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stressQ22010800
Plasma cell differentiation requires the transcription factor XBP-1Q24291453
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans developmentQ24292104
XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cellsQ24658399
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeastQ27937464
Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeastQ28140422
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNAQ28214814
Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stressQ28506667
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glandsQ28510479
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networksQ28591575
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein responseQ28611502
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein responseQ29547299
Phase separation of integral membrane proteins in Triton X-114 solutionQ29547600
A common mechanism of PLP/DM20 misfolding causes cysteine-mediated endoplasmic reticulum retention in oligodendrocytes and Pelizaeus-Merzbacher diseaseQ30480632
On the mechanism of sensing unfolded protein in the endoplasmic reticulumQ34230593
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiationQ34345459
The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein responseQ35170906
Regulation of plasma-cell developmentQ36058417
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.Q36322684
Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis.Q36393034
XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cellsQ36402768
Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides.Q36949766
The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cellsQ37181198
Signal peptide cleavage of a type I membrane protein, HCMV US11, is dependent on its membrane anchorQ39714879
B lymphocyte-specific, Cre-mediated mutagenesis in miceQ39719513
Misfolded BRICHOS SP-C mutant proteins induce apoptosis via caspase-4- and cytochrome c-related mechanismsQ40116328
Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretionQ40669445
Murine CD1d-restricted T cell recognition of cellular lipidsQ40894441
Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.Q41423746
Inhibition of N-linked oligosaccharide trimming mannosidases blocks human B cell developmentQ42571853
Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis.Q42832143
Activation of an unfolded protein response during differentiation of antibody-secreting B cells.Q52113898
Immunoglobulin heavy chain mRNA in mitogen-stimulated B cellsQ67527318
Transcriptional control of mu- and kappa-gene expression in resting and bacterial lipopolysaccharide-activated normal B cellsQ70344938
Degradation of proteins from the ER of S. cerevisiae requires an intact unfolded protein response pathwayQ73958524
Enhanced B-1 cell development, but impaired IgG antibody responses in mice deficient in secreted IgMQ74557530
TLR agonists selectively promote terminal plasma cell differentiation of B cell subsets specialized in thymus-independent responsesQ80427941
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectprotein foldingQ847556
glycosylationQ898365
P304page(s)3690-3699
P577publication date2009-08-26
P1433published inJournal of ImmunologyQ3521441
P1476titleXBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis
P478volume183

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