Sequence-specific interactions of Rep proteins with ssDNA in the AT-rich region of the plasmid replication origin

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Sequence-specific interactions of Rep proteins with ssDNA in the AT-rich region of the plasmid replication origin is …
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scholarly articleQ13442814

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P356DOI10.1093/NAR/GKU453
P932PMC publication ID4081077
P698PubMed publication ID24838560
P5875ResearchGate publication ID265825519

P50authorKatarzyna WegrzynQ57021955
Katarzyna BuryQ64187186
Fernando Moreno-HerreroQ39997618
P2093author name stringIgor Konieczny
Magdalena Rajewska
Maria Eugenia Fuentes-Perez
P2860cites workThe DNA binding domain of the initiator protein DnaAQ24568280
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A common mechanism for the ATP-DnaA-dependent formation of open complexes at the replication originQ27649681
DNA stretching by bacterial initiators promotes replication origin openingQ27674672
DNA replication in eukaryotic cellsQ28131747
The DNA unwinding element: a novel, cis-acting component that facilitates opening of the Escherichia coli replication originQ28254988
The replication of plasmid pSC101Q28280481
Mechanism of origin unwinding: sequential binding of DnaA to double- and single-stranded DNAQ28360242
Primase, the dnaG protein of Escherichia coli. An enzyme which starts DNA chainsQ34049833
DNA polymerase III holoenzyme: structure and function of a chromosomal replicating machineQ34058015
Origin remodeling and opening in bacteria rely on distinct assembly states of the DnaA initiatorQ34107456
AT-rich region and repeated sequences - the essential elements of replication origins of bacterial replicons.Q34233413
E. coli SeqA protein binds oriC in two different methyl-modulated reactions appropriate to its roles in DNA replication initiation and origin sequestrationQ34294934
Differentiation of the DnaA-oriC subcomplex for DNA unwinding in a replication initiation complex.Q34297167
Initiator protein pi can bind independently to two domains of the gamma origin core of plasmid R6K: the direct repeats and the A+T-rich segmentQ34596064
Mechanism of recruitment of DnaB helicase to the replication origin of the plasmid pSC101.Q34791013
DNA or RNA priming of bacteriophage G4 DNA synthesis by Escherichia coli dnaG proteinQ35035406
Strategies for helicase recruitment and loading in bacteriaQ35043857
Common domains in the initiators of DNA replication in Bacteria, Archaea and Eukarya: combined structural, functional and phylogenetic perspectives.Q35066207
Replication initiator protein RepE of mini-F plasmid: functional differentiation between monomers (initiator) and dimers (autogenous repressor).Q35200597
Multicopy plasmids are clustered and localized in Escherichia coliQ35264445
Preponderance of Fis-binding sites in the R6K gamma origin and the curious effect of the penicillin resistance marker on replication of this origin in the absence of FisQ35611146
Host participation in plasmid maintenance: dependence upon dnaA of replicons derived from P1 and FQ35611641
The integration host factor of Escherichia coli binds to multiple sites at plasmid R6K gamma origin and is essential for replicationQ36002426
Analysis of the DNA-binding domain of Escherichia coli DnaA protein.Q52971588
WSXM: a software for scanning probe microscopy and a tool for nanotechnology.Q53481540
The arc two-component signal transduction system inhibits in vitro Escherichia coli chromosomal initiation.Q53898983
Opposed actions of regulatory proteins, DnaA and IciA, in opening the replication origin of Escherichia coliQ54057494
Initiation protein induced helix destabilization at the lambda origin: a prepriming step in DNA replicationQ69820081
The Escherichia coli dnaB replication protein is a DNA helicaseQ70134303
DNA height in scanning force microscopyQ73208392
The central region of RepE initiator protein of mini-F plasmid plays a crucial role in dimerization required for negative replication controlQ73940856
Positioning and the specific sequence of each 13-mer motif are critical for activity of the plasmid RK2 replication originQ81064499
Bacterial partitioning proteins affect the subcellular location of broad-host-range plasmid RK2Q81896511
Transformation of freshwater and marine caulobacters by electroporationQ36126015
Requirement of the Escherichia coli dnaA gene product for plasmid F maintenanceQ36259197
Specific mutations within the AT-rich region of a plasmid replication origin affect either origin opening or helicase loadingQ36837514
Iteron inhibition of plasmid RK2 replication in vitro: evidence for intermolecular coupling of replication origins as a mechanism for RK2 replication controlQ37404043
iciA, an Escherichia coli gene encoding a specific inhibitor of chromosomal initiation of replication in vitroQ37508279
A protein that binds to the P1 origin core and the oriC 13mer region in a methylation-specific fashion is the product of the host seqA geneQ37621716
Copy-up mutants of the plasmid RK2 replication initiation protein are defective in coupling RK2 replication originsQ37661651
Building the bacterial orisome: high-affinity DnaA recognition plays a role in setting the conformation of oriC DNAQ37712455
Strand-specific loading of DnaB helicase by DnaA to a substrate mimicking unwound oriC.Q38361264
Binding of Escherichia coli primary replicative helicase DnaB protein to single-stranded DNA. Long-range allosteric conformational changes within the protein hexamerQ38361481
A model for initiation at origins of DNA replicationQ39256067
Interaction of the IciA protein with AT-rich regions in plasmid replication originsQ39716316
Where does bacterial replication start? Rules for predicting the oriC regionQ39752100
Parental strand recognition of the DNA replication origin by the outer membrane in Escherichia coli.Q40793427
Highly organized DnaA-oriC complexes recruit the single-stranded DNA for replication initiationQ41577510
Structural basis for ATP-dependent DnaA assembly and replication-origin remodelingQ41791841
Topological characterization of the DnaA-oriC complex using single-molecule nanomanipuation.Q41960283
Open complex formation by DnaA initiation protein at the Escherichia coli chromosomal origin requires the 13-mers precisely spaced relative to the 9-mersQ42597743
Role of TrfA and DnaA proteins in origin opening during initiation of DNA replication of the broad host range plasmid RK2.Q42661197
The localized melting of mini-F origin by the combined action of the mini-F initiator protein (RepE) and HU and DnaA of Escherichia coliQ44029616
Duplex opening by dnaA protein at novel sequences in initiation of replication at the origin of the E. coli chromosomeQ44347022
Replication origin of the broad host range plasmid RK2. Positioning of various motifs is critical for initiation of replication.Q45999258
Helicase delivery and activation by DnaA and TrfA proteins during the initiation of replication of the broad host range plasmid RK2.Q46088788
Plasmid host-range: restrictions to F replication in PseudomonasQ46567220
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)7807-7818
P577publication date2014-05-16
P1433published inNucleic Acids ResearchQ135122
P1476titleSequence-specific interactions of Rep proteins with ssDNA in the AT-rich region of the plasmid replication origin
P478volume42

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cites work (P2860)
Q26781545Choosing a suitable method for the identification of replication origins in microbial genomes
Q90288983Crystal Structure of an Unusual Single-Stranded DNA-Binding Protein Encoded by Staphylococcal Cassette Chromosome Elements
Q50959628Defining the crucial domain and amino acid residues in bacterial Lon protease for DNA binding and processing of DNA-interacting substrates.
Q49243600Expression and replication of virus-like circular DNA in human cells
Q33580338Handcuffing reversal is facilitated by proteases and replication initiator monomers
Q64255680Novel classes of replication-associated transcripts discovered in viruses
Q28067371Opening the Strands of Replication Origins-Still an Open Question
Q35946244Plasmid replication initiator interactions with origin 13-mers and polymerase subunits contribute to strand-specific replisome assembly
Q46282732Regulatory dynamics in the ternary DnaA complex for initiation of chromosomal replication in Escherichia coli.
Q26738704Replisome Assembly at Bacterial Chromosomes and Iteron Plasmids

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