| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Michel C. Nussenzweig | Q24804686 |
| P2093 | author name string | André Nussenzweig | |
| P2860 | cites work | Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair | Q21145054 |
| Interchromosomal associations between alternatively expressed loci | Q22122480 | ||
| Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2) | Q24290325 | ||
| The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks | Q24311761 | ||
| Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching | Q24569801 | ||
| Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers | Q24625794 | ||
| How the fanconi anemia pathway guards the genome | Q24634556 | ||
| Human CtIP promotes DNA end resection | Q24646062 | ||
| Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes | Q24649590 | ||
| CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle. | Q39862482 | ||
| Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV-deficient B cells | Q39918892 | ||
| Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair. | Q40028909 | ||
| Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer | Q40099013 | ||
| Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells | Q40191456 | ||
| A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex | Q40582495 | ||
| The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts | Q41710133 | ||
| Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation | Q41874223 | ||
| Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction | Q41908763 | ||
| 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility | Q41919899 | ||
| Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity | Q42260473 | ||
| Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells. | Q42271523 | ||
| DNA helicases Sgs1 and BLM promote DNA double-strand break resection | Q42750184 | ||
| Constitutive expression of AID leads to tumorigenesis | Q42944928 | ||
| Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice | Q44194766 | ||
| Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination | Q44575368 | ||
| AID is required for c-myc/IgH chromosome translocations in vivo | Q45021537 | ||
| Two levels of protection for the B cell genome during somatic hypermutation. | Q46755254 | ||
| H2AX prevents DNA breaks from progressing to chromosome breaks and translocations | Q46904251 | ||
| Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair | Q46942139 | ||
| Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes | Q47982616 | ||
| V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors. | Q52200236 | ||
| Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations. | Q53965557 | ||
| Mre11: roles in DNA repair beyond homologous recombination. | Q55052114 | ||
| Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing | Q59086518 | ||
| Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors | Q64387467 | ||
| The RAG1/RAG2 complex constitutes a 3' flap endonuclease: implications for junctional diversity in V(D)J and transpositional recombination | Q73353796 | ||
| Chromosomal rearrangements and microRNAs: a new cancer link with clinical implications | Q24683729 | ||
| The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations | Q24685574 | ||
| DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 | Q28131715 | ||
| Comprehensive mapping of long-range interactions reveals folding principles of the human genome | Q28131819 | ||
| Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX | Q28139663 | ||
| DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation | Q28141630 | ||
| Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas | Q28207345 | ||
| Cancer susceptibility and the functions of BRCA1 and BRCA2 | Q28217784 | ||
| Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks | Q28235091 | ||
| IgH class switching and translocations use a robust non-classical end-joining pathway | Q28241679 | ||
| A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency | Q28256846 | ||
| The taming of a transposon: V(D)J recombination and the immune system | Q28270945 | ||
| Genetic steps of mammalian homologous repair with distinct mutagenic consequences | Q28287955 | ||
| AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching | Q28366125 | ||
| DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse | Q28511262 | ||
| Genomic instability in mice lacking histone H2AX | Q28589826 | ||
| The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination | Q28592784 | ||
| Focusing on foci: H2AX and the recruitment of DNA-damage response factors | Q28611373 | ||
| Role of mammalian Mre11 in classical and alternative nonhomologous end joining | Q28751872 | ||
| 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks | Q29465538 | ||
| Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme | Q29547201 | ||
| ATM and related protein kinases: safeguarding genome integrity | Q29547735 | ||
| MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings | Q29614424 | ||
| Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death | Q29614845 | ||
| How shelterin protects mammalian telomeres | Q29615744 | ||
| PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways | Q29616041 | ||
| Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks | Q30480374 | ||
| ATM prevents the persistence and propagation of chromosome breaks in lymphocytes | Q33289263 | ||
| Myc dynamically and preferentially relocates to a transcription factory occupied by Igh | Q33290425 | ||
| Modeling oncogenic translocations: distinct roles for double-strand break repair pathways in translocation formation in mammalian cells | Q36525084 | ||
| H2AX haploinsufficiency modifies genomic stability and tumor susceptibility | Q36533572 | ||
| Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG. | Q36654350 | ||
| 53BP1 facilitates long-range DNA end-joining during V(D)J recombination | Q36682376 | ||
| Positional stability of single double-strand breaks in mammalian cells | Q36742792 | ||
| Molecular mechanisms of antibody somatic hypermutation. | Q36747477 | ||
| The impact of translocations and gene fusions on cancer causation | Q36760027 | ||
| Evolution of the immunoglobulin heavy chain class switch recombination mechanism | Q36845675 | ||
| AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development | Q36853393 | ||
| Antigen receptor diversification and chromosome translocations | Q36887122 | ||
| Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction | Q36901365 | ||
| Ctp1/CtIP and the MRN complex collaborate in the initial steps of homologous recombination | Q36998366 | ||
| The biochemistry of somatic hypermutation | Q37096080 | ||
| Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation | Q37104813 | ||
| Recurrent gene fusions in prostate cancer | Q37194503 | ||
| MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks | Q37234327 | ||
| Roles for NBS1 in alternative nonhomologous end-joining of V(D)J recombination intermediates. | Q37246230 | ||
| AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations | Q37269390 | ||
| Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination | Q37273095 | ||
| Multiple functions of MRN in end-joining pathways during isotype class switching | Q37291987 | ||
| Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin. | Q37347174 | ||
| Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney | Q38291974 | ||
| Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer | Q39766844 | ||
| Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells | Q39820516 | ||
| Chromosome fusions following telomere loss are mediated by single-strand annealing | Q33362700 | ||
| Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region. | Q33573534 | ||
| AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations | Q33588393 | ||
| Role of the translocation partner in protection against AID-dependent chromosomal translocations | Q33591714 | ||
| Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4. | Q33656097 | ||
| Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70 | Q33733981 | ||
| 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination | Q33794964 | ||
| Mechanisms promoting translocations in editing and switching peripheral B cells | Q34008189 | ||
| Antibody regulation of B cell development | Q34076152 | ||
| Activation of MYC in a masked t(8;17) translocation results in an aggressive B-cell leukemia | Q34319410 | ||
| Negative regulation of activation-induced cytidine deaminase in B cells | Q34479651 | ||
| ATM stabilizes DNA double-strand-break complexes during V(D)J recombination. | Q34541828 | ||
| Cellular senescence in cancer and aging | Q34581486 | ||
| Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70. | Q34728634 | ||
| An oncogene-induced DNA damage model for cancer development | Q34759268 | ||
| Mechanism and regulation of class switch recombination | Q34764888 | ||
| Somatic hypermutation of the B cell receptor genes B29 (Igbeta, CD79b) and mb1 (Igalpha, CD79a). | Q34922043 | ||
| V(D)J recombination deficiencies | Q35001266 | ||
| Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis | Q35208288 | ||
| INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53. | Q35208402 | ||
| H2AX may function as an anchor to hold broken chromosomal DNA ends in close proximity | Q35623763 | ||
| RAGs and regulation of autoantibodies | Q35698505 | ||
| Mechanisms of B-cell lymphoma pathogenesis | Q36085626 | ||
| Role of genomic instability and p53 in AID-induced c-myc-Igh translocations. | Q36146840 | ||
| Chromosomal reinsertion of broken RSS ends during T cell development | Q36229012 | ||
| Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination. | Q36229482 | ||
| Lymphocyte antigen receptor gene assembly: multiple layers of regulation | Q36232738 | ||
| Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma | Q36267192 | ||
| BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci | Q36322298 | ||
| Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification | Q36376595 | ||
| Alternative endings. | Q36392830 | ||
| Biochemistry of V(D)J recombination. | Q36397181 | ||
| DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination | Q36509842 | ||
| Common fragile sites as targets for chromosome rearrangements | Q36522587 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 27-38 | |
| P577 | publication date | 2010-04-01 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | Origin of chromosomal translocations in lymphoid cancer | |
| P478 | volume | 141 |
| Q36856274 | 53BP1 alters the landscape of DNA rearrangements and suppresses AID-induced B cell lymphoma |
| Q39245050 | A Chemoattractant-Guided Walk Through Lymphopoiesis: From Hematopoietic Stem Cells to Mature B Lymphocytes |
| Q92083681 | A Functional Assay to Assess Toxicity During Murine B Cell Development In Vitro |
| Q42146685 | A hypomorphic Artemis human disease allele causes aberrant chromosomal rearrangements and tumorigenesis |
| Q36245176 | A recurrent fusion gene in high-grade endometrial stromal sarcoma: a new tool for diagnosis and therapy? |
| Q34133261 | A source of the single-stranded DNA substrate for activation-induced deaminase during somatic hypermutation |
| Q37164471 | AID hits the jackpot when missing the target |
| Q33839428 | AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants |
| Q28265992 | AID targeting: old mysteries and new challenges |
| Q34550504 | AID-initiated DNA lesions are differentially processed in distinct B cell populations |
| Q37683558 | AIDing Chromatin and Transcription-Coupled Orchestration of Immunoglobulin Class-Switch Recombination. |
| Q41578158 | ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma |
| Q42742811 | ATMIN: a new tumor suppressor in developing B cells |
| Q90301202 | Activation-Induced Cytidine Deaminase Regulates Fibroblast Growth Factor/Extracellular Signal-Regulated Kinases Signaling to Achieve the Naïve Pluripotent State During Reprogramming |
| Q37994933 | Activation-induced cytidine deaminase in antibody diversification and chromosome translocation |
| Q34357060 | Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5 |
| Q50717173 | Adaptive B cell responses in rituximab-treated diffuse large B cell lymphoma patients during complete remission |
| Q42582794 | Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation |
| Q35682245 | An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway |
| Q35589706 | Androgen receptor-driven chromatin looping in prostate cancer |
| Q30275229 | Antibody-siRNA conjugates: drugging the undruggable for anti-leukemic therapy |
| Q47649609 | Ataxia telangiectasia syndrome: moonlighting ATM. |
| Q26863728 | Ataxia-telangiectasia: future prospects |
| Q34748194 | B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity |
| Q35923364 | BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair |
| Q36216511 | Biochemical analysis of hypermutation by the deoxycytidine deaminase APOBEC3A. |
| Q38115457 | Biological implications and regulatory mechanisms of long-range chromosomal interactions. |
| Q38000577 | Burkitt lymphoma: the role of Epstein-Barr virus revisited |
| Q64043732 | Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice |
| Q36056628 | Cell cycle- and DNA repair pathway-specific effects of apoptosis on tumor suppression |
| Q35127960 | Centrosome-kinase fusions promote oncogenic signaling and disrupt centrosome function in myeloproliferative neoplasms |
| Q38040618 | Chromosomal translocations among the healthy human population: implications in oncogenesis |
| Q35243380 | Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining. |
| Q37100081 | Clinical and Biologic Significance of MYC Genetic Mutations in De Novo Diffuse Large B-cell Lymphoma |
| Q36608103 | Close proximity to Igh is a contributing factor to AID-mediated translocations. |
| Q36439752 | Combined deletion of Xrcc4 and Trp53 in mouse germinal center B cells leads to novel B cell lymphomas with clonal heterogeneity |
| Q48250994 | Cutting Edge: The Transcription Factor Sox2 Regulates AID Expression in Class-Switched B Cells. |
| Q36282872 | DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes |
| Q38118223 | DNA damage response: three levels of DNA repair regulation |
| Q50133428 | DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions. |
| Q36443382 | DNA double-strand breaks with 5' adducts are efficiently channeled to the DNA2-mediated resection pathway |
| Q37505517 | DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment |
| Q84617107 | Dangerous Liaisons: Fanconi Anemia and Toxic Nonhomologous End Joining in DNA Crosslink Repair |
| Q33757410 | Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes |
| Q37065189 | Defining chromosomal translocation risks in cancer. |
| Q35849249 | Dendritic cell-mediated activation-induced cytidine deaminase (AID)-dependent induction of genomic instability in human myeloma. |
| Q35975147 | Detecting DNA double-stranded breaks in mammalian genomes by linear amplification-mediated high-throughput genome-wide translocation sequencing |
| Q52861943 | Development of Mouse Model Systems of Germinal Center Lymphomas. |
| Q33925876 | Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes |
| Q54518451 | Differential positioning and close spatial proximity of translocation-prone genes in nonmalignant B-cells from multiple myeloma patients. |
| Q34904095 | Differential programming of B cells in AID deficient mice |
| Q36002464 | EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele |
| Q27930266 | Effect of nuclear architecture on the efficiency of double-strand break repair |
| Q37683027 | Emerging roles of Jab1/CSN5 in DNA damage response, DNA repair, and cancer. |
| Q92409432 | Epigenetic Priming in Childhood Acute Lymphoblastic Leukemia |
| Q34831630 | Epigenetic targeting of activation-induced cytidine deaminase. |
| Q37844463 | Fanconi anemia: a disorder defective in the DNA damage response |
| Q90731225 | Functional deficiency of DNA repair gene EXO5 results in androgen-induced genomic instability and prostate tumorigenesis |
| Q55092495 | Generating and repairing genetically programmed DNA breaks during immunoglobulin class switch recombination. |
| Q33690522 | Generation and repair of AID-initiated DNA lesions in B lymphocytes |
| Q38626707 | Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells |
| Q37417907 | Genomic Architecture may Influence Recurrent Chromosomal Translocation Frequency in the Igh Locus |
| Q38364884 | Germinal centres and B cell lymphomagenesis |
| Q91660568 | Glyphosate induces benign monoclonal gammopathy and promotes multiple myeloma progression in mice |
| Q37505538 | Histone H2AX suppresses translocations in lymphomas of Eμ-c-Myc transgenic mice that contain a germline amplicon of tumor-promoting genes |
| Q38595978 | Histone deacetylase inhibitors and epigenetic regulation in lymphoid malignancies |
| Q28259208 | Homology and enzymatic requirements of microhomology-dependent alternative end joining |
| Q37865973 | How does DNA break during chromosomal translocations? |
| Q34136920 | Identification of chromosomal translocation hotspots via scan statistics |
| Q36875409 | Identification of core DNA elements that target somatic hypermutation. |
| Q36249443 | Identification of human germinal center light and dark zone cells and their relationship to human B-cell lymphomas |
| Q27337186 | Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks |
| Q45652459 | In vivo tungsten exposure alters B-cell development and increases DNA damage in murine bone marrow |
| Q41692410 | Incidence of cancers in patients with atherosclerotic cardiovascular diseases |
| Q28118339 | Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity |
| Q36547669 | Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching |
| Q38504989 | Mechanisms and clinical applications of chromosomal instability in lymphoid malignancy |
| Q38843257 | Mechanisms of human lymphoid chromosomal translocations |
| Q38078491 | Mechanisms of programmed DNA lesions and genomic instability in the immune system. |
| Q34143276 | Mechanisms that can promote peripheral B-cell lymphoma in ATM-deficient mice. |
| Q38225013 | Mechanisms underlying mutational signatures in human cancers |
| Q38645574 | Melanomacrophage Centers As a Histological Indicator of Immune Function in Fish and Other Poikilotherms |
| Q34053726 | Mobile elements and viral integrations prompt considerations for bacterial DNA integration as a novel carcinogen |
| Q36061440 | Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity |
| Q64104799 | Molecular mechanisms and pathobiology of oncogenic fusion transcripts in epithelial tumors |
| Q36079387 | Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation |
| Q24620915 | Mutational processes molding the genomes of 21 breast cancers |
| Q24595213 | Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma |
| Q33836777 | New Insights in the Cytogenetic Practice: Karyotypic Chaos, Non-Clonal Chromosomal Alterations and Chromosomal Instability in Human Cancer and Therapy Response |
| Q64106669 | New insights emerge as antibody repertoire diversification meets chromosome conformation |
| Q35589869 | Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNA |
| Q38194755 | Non-homologous end joining often uses microhomology: implications for alternative end joining |
| Q34412094 | Novel levamisole derivative induces extrinsic pathway of apoptosis in cancer cells and inhibits tumor progression in mice |
| Q38505169 | Novel molecular mechanism for generating NK-cell fitness and memory |
| Q36187330 | Oncogenic Myc translocations are independent of chromosomal location and orientation of the immunoglobulin heavy chain locus |
| Q36116985 | Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching. |
| Q28585503 | PTIP promotes chromatin changes critical for immunoglobulin class switch recombination |
| Q34245261 | Pathogenesis of human B cell lymphomas |
| Q36190407 | Perspectives on common variable immune deficiency |
| Q38716411 | Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells |
| Q34262604 | Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1. |
| Q36453190 | Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression |
| Q84279386 | Potential G-quadruplex formation at breakpoint regions of chromosomal translocations in cancer may explain their fragility |
| Q42317970 | RAG1/2 induces genomic insertions by mobilizing DNA into RAG1/2-independent breaks |
| Q28087424 | RNA Exosome Regulates AID DNA Mutator Activity in the B Cell Genome |
| Q37730047 | Regulating infidelity: RNA-mediated recruitment of AID to DNA during class switch recombination |
| Q35125130 | Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1. |
| Q34115234 | Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair |
| Q27000758 | Related Mechanisms of Antibody Somatic Hypermutation and Class Switch Recombination |
| Q33694621 | Repair of DNA double-strand breaks by templated nucleotide sequence insertions derived from distant regions of the genome |
| Q51180033 | Robust immunoglobulin class switch recombination and end joining in Parp9-deficient mice |
| Q59791887 | Role and Regulation of Pro-survival BCL-2 Proteins in Multiple Myeloma |
| Q28266265 | Role of non-homologous end joining in V(D)J recombination |
| Q34308191 | Roles for histone H3K4 methyltransferase activities during immunoglobulin class-switch recombination |
| Q27670829 | Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding |
| Q38048886 | Sequence and structural basis for chromosomal fragility during translocations in cancer |
| Q92875107 | TRAF6 mediates human DNA2 polyubiquitination and nuclear localization to maintain nuclear genome integrity |
| Q38005211 | Targeted gene therapies: tools, applications, optimization |
| Q38085501 | Targeting pathological B cell receptor signalling in lymphoid malignancies |
| Q34715036 | The AID-induced DNA damage response in chromatin |
| Q36712849 | The ATM signaling network in development and disease |
| Q27861055 | The DNA Damage Response: Making It Safe to Play with Knives |
| Q34161115 | The FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers. |
| Q37478615 | The FEN1 L209P mutation interferes with long-patch base excision repair and induces cellular transformation |
| Q41725101 | The RAG recombinase dictates functional heterogeneity and cellular fitness in natural killer cells |
| Q37549732 | The aryl hydrocarbon receptor controls cell-fate decisions in B cells. |
| Q28083266 | The biology behind PI3K inhibition in chronic lymphocytic leukaemia |
| Q34044132 | The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers |
| Q26995532 | The consequences of chromosomal aneuploidy on the transcriptome of cancer cells |
| Q38495121 | The molecular pathogenesis of B-cell non-Hodgkin lymphoma |
| Q36951546 | The origin of recurrent translocations in recombining lymphocytes: a balance between break frequency and nuclear proximity. |
| Q43091743 | The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry |
| Q28256889 | The response to and repair of RAG-mediated DNA double-strand breaks |
| Q37076293 | The structure of ends determines the pathway choice and Mre11 nuclease dependency of DNA double-strand break repair |
| Q92087400 | Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation |
| Q36646380 | Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells. |
| Q35773181 | Translocation capture sequencing: a method for high throughput mapping of chromosomal rearrangements |
| Q35304991 | Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes |
| Q24621737 | Unbalanced replication as a major source of genetic instability in cancer cells |
| Q36171109 | Unexpected effects of different genetic backgrounds on identification of genomic rearrangements via whole-genome next generation sequencing |
| Q39322967 | V(D)J Recombination Exploits DNA Damage Responses to Promote Immunity |
| Q40166335 | What Are the Primary Limitations in B-Cell Affinity Maturation, and How Much Affinity Maturation Can We Drive with Vaccination? Breaking through Immunity's Glass Ceiling |
| Q91644110 | Wwox Deletion in Mouse B Cells Leads to Genomic Instability, Neoplastic Transformation, and Monoclonal Gammopathies |
| Q41918614 | XLF/Cernunnos: An important but puzzling participant in the nonhomologous end joining DNA repair pathway. |
| Q98293338 | XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells |
| Q34846094 | Yeast pol4 promotes tel1-regulated chromosomal translocations |
| Q35163512 | miR-182 is largely dispensable for adaptive immunity: lack of correlation between expression and function |
| Q37474987 | β-Catenin induces T-cell transformation by promoting genomic instability |
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