ppGpp conjures bacterial virulence

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ppGpp conjures bacterial virulence is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1128/MMBR.00046-09
P932PMC publication ID2884408
P698PubMed publication ID20508246
P5875ResearchGate publication ID44635837

P50authorMichele S. SwansonQ58371379
Sarah L SvenssonQ59684641
P2093author name stringErin C Gaynor
Zachary D Dalebroux
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The LetA-RsmYZ-CsrA regulatory cascade, together with RpoS and PmrA, post-transcriptionally regulates stationary phase activation of Legionella pneumophila Icm/Dot effectorsQ28243105
Induction of cystic forms by different stress conditions in Borrelia burgdorferiQ28245041
Acyl carrier protein/SpoT interaction, the switch linking SpoT-dependent stress response to fatty acid metabolismQ28271588
Control of bacterial transcription, translation and replication by (p)ppGppQ28273687
(p)ppGpp: still magical?Q28278758
TraR, a homolog of a RNAP secondary channel interactor, modulates transcriptionQ28474472
The stringent response of Mycobacterium tuberculosis is required for long-term survivalQ28486427
The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in miceQ28486838
CodY of Streptococcus pneumoniae: link between nutritional gene regulation and colonizationQ36422216
Does Pseudomonas aeruginosa use intercellular signalling to build biofilm communities?Q36616551
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The Francisella pathogenicity island protein PdpD is required for full virulence and associates with homologues of the type VI secretion systemQ36747345
Role of the DksA-like protein in the pathogenesis and diverse metabolic activity of Campylobacter jejuniQ36747360
Molecular and genetic basis of pathogenesis in Francisella tularensisQ36775022
Global regulation by (p)ppGpp and CodY in Streptococcus mutansQ36804362
Enteropathogenic and enterohemorrhagic Escherichia coli virulence gene regulation.Q36852367
Campylobacter jejuni: molecular biology and pathogenesisQ36912126
Salmonella enterica serovar gallinarum requires ppGpp for internalization and survival in animal cellsQ36933192
Passage through Tetrahymena tropicalis triggers a rapid morphological differentiation in Legionella pneumophilaQ36974544
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Using every trick in the book: the Pla surface protease of Yersinia pestisQ36984047
Regulation of cell growth during serum starvation and bacterial survival in macrophages by the bifunctional enzyme SpoT in Helicobacter pylori.Q36994425
The Escherichia coli GTPase CgtAE cofractionates with the 50S ribosomal subunit and interacts with SpoT, a ppGpp synthetase/hydrolaseQ37007216
Salmonellae interplay with host cellsQ37008201
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SigmaS controls multiple pathways associated with intracellular multiplication of Legionella pneumophilaQ37157034
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Transcriptional regulation of Vibrio cholerae hemagglutinin/protease by the cyclic AMP receptor protein and RpoSQ37513677
RpoS is not central to the general stress response in Borrelia burgdorferi but does control expression of one or more essential virulence determinantsQ37582867
An alternative strategy for bacterial ribosome synthesis: Bacillus subtilis rRNA transcription regulationQ37605095
Regulatory roles of the bacterial nitrogen-related phosphotransferase systemQ37702617
Regulation of the fimB promoter: a case of differential regulation by ppGpp and DksA in vivo.Q38293420
Nutritional control of elongation of DNA replication by (p)ppGppQ38303861
Life in protein-rich environments: the relA-independent response of Streptococcus pyogenes to amino acid starvationQ38305669
SpoT governs Legionella pneumophila differentiation in host macrophagesQ46223959
Metabolic diversity in Campylobacter jejuni enhances specific tissue colonizationQ46256669
Roles of Brucella abortus SpoT in morphological differentiation and intramacrophagic replicationQ46471498
Microarray analysis of the transcriptional responses of Clostridium difficile to environmental and antibiotic stressQ46595628
ppGpp and DksA likely regulate the activity of the extracytoplasmic stress factor sigmaE in Escherichia coli by both direct and indirect mechanisms.Q46845845
Immune response induced by Salmonella typhimurium defective in ppGpp synthesisQ46852567
Identification and functional analysis of novel (p)ppGpp synthetase genes in Bacillus subtilisQ46859843
The stringent response of Bacillus anthracis contributes to sporulation but not to virulenceQ46874260
Molecular characterization of vibrio cholerae DeltarelA DeltaspoT double mutantsQ46925253
Linking the nutritional status of Streptococcus pyogenes to alteration of transcriptional gene expression: the action of CodY and RelA.Q46986388
Transcriptional control of the antimicrobial peptide resistance ugtL gene by the Salmonella PhoP and SlyA regulatory proteinsQ47316351
RNA polymerase mutants that destabilize RNA polymerase-promoter complexes alter NTP-sensing by rrn P1 promotersQ47923669
The bacterial signal molecule, ppGpp, mediates the environmental regulation of both the invasion and intracellular virulence gene programs of SalmonellaQ50077977
The putative invasion protein chaperone SicA acts together with InvF to activate the expression of Salmonella typhimurium virulence genesQ50122261
Effects of DksA and ClpP protease on sigma S production and virulence in Salmonella typhimuriumQ50123216
Live oral avirulent Salmonella vaccinesQ50157012
Quantitative reverse transcription polymerase chain reaction analysis of Vibrio cholerae cells entering the viable but non-culturable state and starvation in response to cold shock.Q51234974
Development of intracellular bacterial communities of uropathogenic Escherichia coli depends on type 1 pili.Q51986442
ppGpp with DksA controls gene expression in the locus of enterocyte effacement (LEE) pathogenicity island of enterohaemorrhagic Escherichia coli through activation of two virulence regulatory genes.Q53613130
Properties of RNA polymerase bypass mutants: implications for the role of ppGpp and its co-factor DksA in controlling transcription dependent on sigma54.Q54442568
Succinic semialdehyde couples stress response to quorum-sensing signal decay in Agrobacterium tumefaciens.Q54456738
(p)ppGpp regulates type 1 fimbriation of Escherichia coli by modulating the expression of the site-specific recombinase FimB.Q54462653
The guanosine tetraphosphate (ppGpp) alarmone, DksA and promoter affinity for RNA polymerase in regulation of sigma-dependent transcription.Q54466501
Virulence strategies for infecting phagocytes deduced from the in vivo transcriptional program of Legionella pneumophilaQ57954214
The stringent response mediator Rsh is required for Brucella melitensis and Brucella suis virulence, and for expression of the type IV secretion system virBQ59259370
The mechanism of amino acid control of guanylate and adenylate biosynthesisQ69947073
Chromosomal restriction fragment length polymorphism analysis of Escherichia coli strains causing recurrent urinary tract infections in young womenQ71922985
NapA protects Helicobacter pylori from oxidative stress damage, and its production is influenced by the ferric uptake regulatorQ73397265
Co-ordination of legionella pneumophila virulence with entry into stationary phase by ppGppQ78127783
Legionella pneumophila CsrA is a pivotal repressor of transmission traits and activator of replicationQ79293753
Growth phase-associated changes in the transcriptome and proteome of Streptococcus pyogenesQ80706431
Three gene products govern (p)ppGpp production by Streptococcus mutansQ80832099
The identity of the transcription +1 position is crucial for changes in gene expression in response to amino acid starvation in Bacillus subtilisQ81143775
Polyphosphate kinase: a new colonization factor of Helicobacter pyloriQ81312878
Functional analysis of spoT, relA and dksA genes on quinolone tolerance in Pseudomonas aeruginosa under nongrowing conditionQ83177545
Stress response and pathogenic potential of Campylobacter jejuni cells exposed to starvationQ83937689
CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistenceQ28486907
Cloning and characterization of a bifunctional RelA/SpoT homologue from Mycobacterium tuberculosisQ28487236
Polyphosphate kinase is involved in stress-induced mprAB-sigE-rel signalling in mycobacteriaQ28487420
Modulation of quorum sensing in Pseudomonas aeruginosa through alteration of membrane propertiesQ28492526
Inhibition of quorum sensing by a Pseudomonas aeruginosa dksA homologueQ28493089
Role of RelA of Streptococcus mutans in global control of gene expressionQ28493281
Pseudomonas aeruginosa relA contributes to virulence in Drosophila melanogasterQ28493313
Characterization of relA and codY mutants of Listeria monocytogenes: identification of the CodY regulon and its role in virulenceQ29346597
Carbon catabolite repression in bacteria: many ways to make the most out of nutrientsQ29615329
Yersinia pestis--etiologic agent of plagueQ29619320
Gene expression profiling of Helicobacter pylori reveals a growth-phase-dependent switch in virulence gene expression.Q30477751
Positive effects of multiple pch genes on expression of the locus of enterocyte effacement genes and adherence of enterohaemorrhagic Escherichia coli O157 : H7 to HEp-2 cellsQ31095273
Isolation of salt-sensitive mutants from Sinorhizobium meliloti and characterization of genes involved in salt tolerance.Q31103549
Identification of fevR, a novel regulator of virulence gene expression in Francisella novicidaQ33344342
Pleiotropic effects of a rel mutation on stress survival of Rhizobium etli CNPAF512.Q33392409
Identification of an rsh gene from a Novosphingobium sp. necessary for quorum-sensing signal accumulationQ33406820
Pseudomonas aeruginosa PAO1 preferentially grows as aggregates in liquid batch cultures and disperses upon starvationQ33444732
Comprehensive identification of essential Staphylococcus aureus genes using Transposon-Mediated Differential Hybridisation (TMDH)Q33477111
The role of relA and spoT in Yersinia pestis KIM5 pathogenicityQ33496136
Small molecule control of virulence gene expression in Francisella tularensisQ33513964
DksA and ppGpp directly regulate transcription of the Escherichia coli flagellar cascadeQ33590521
Iron acquisition and metabolism by mycobacteriaQ33635173
Extended survival and persistence of Campylobacter spp. in water and aquatic biofilms and their detection by immunofluorescent-antibody and -rRNA staining.Q33706547
Use of genome-wide expression profiling and mutagenesis to study the intestinal lifestyle of Campylobacter jejuniQ33715945
Differential regulation of Rhizobium etli rpoN2 gene expression during symbiosis and free-living growthQ33733658
A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cellsQ33834748
The stringent response is required for amino acid and nitrate utilization, nod factor regulation, nodulation, and nitrogen fixation in Rhizobium etli.Q33937342
Borrelia burgdorferi rel is responsible for generation of guanosine-3'-diphosphate-5'-triphosphate and growth control.Q33946540
LcrV plague vaccine with altered immunomodulatory propertiesQ33946882
Exploitation of host cells by enteropathogenic Escherichia coliQ33988491
Helicobacter pylori: a eubacterium lacking the stringent response.Q33991034
Stringent response activates quorum sensing and modulates cell density-dependent gene expression in Pseudomonas aeruginosaQ33996839
Fowl typhoid and pullorum disease.Q33997592
dksA is required for intercellular spread of Shigella flexneri via an RpoS-independent mechanism.Q34009042
relA-Independent amino acid starvation response network of Streptococcus pyogenesQ39505676
Invasion of epithelial cells by Yersinia pestis: evidence for a Y. pestis-specific invasinQ39520449
Pseudomonas aeruginosa cell-to-cell signaling is required for virulence in a model of acute pulmonary infectionQ39538040
Multiple factors independently regulate hilA and invasion gene expression in Salmonella enterica serovar typhimuriumQ39538569
Identification of Salmonella typhimurium genes required for colonization of the chicken alimentary tract and for virulence in newly hatched chicksQ39571151
The rel gene is essential for in vitro growth of Staphylococcus aureusQ39587810
Influence of the alternative sigma(28) factor on virulence and flagellum expression of Legionella pneumophilaQ39654070
Characterization of a Legionella pneumophila relA insertion mutant and toles of RelA and RpoS in virulence gene expression.Q39678018
The decrease of guanine nucleotides initiates sporulation of Bacillus subtilisQ39687514
RelA is a component of the nutritional stress activation pathway of the Bacillus subtilis transcription factor sigma B.Q39887750
The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA.Q40110647
Induction of expression of hfq by DksA is essential for Shigella flexneri virulenceQ40223748
Method for staining both acid-fast and chromophobic tubercle bacilli with carbolfuschsinQ40245864
Stable RNA synthesis and its control in Mycoplasma capricolumQ40499407
ppGpp-dependent stationary phase induction of genes on Salmonella pathogenicity island 1.Q40552048
Hypothesis for the role of nutrient starvation in biofilm detachmentQ40621734
Effects of RelA on key virulence properties of planktonic and biofilm populations of Streptococcus mutansQ40634391
A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomesQ40754890
Characterization of the alternative sigma factor sigma54 and the transcriptional regulator FleQ of Legionella pneumophila, which are both involved in the regulation cascade of flagellar gene expressionQ40763582
The Pla surface protease/adhesin of Yersinia pestis mediates bacterial invasion into human endothelial cellsQ40783761
Studies on the effect of starvation on mycobacteriaQ40879525
The LetE protein enhances expression of multiple LetA/LetS-dependent transmission traits by Legionella pneumophilaQ40882993
Two small ncRNAs jointly govern virulence and transmission in Legionella pneumophilaQ41210826
Murine toxin of Yersinia pestis shows phospholipase D activity but is not required for virulence in miceQ41477524
Cell-surface-bound Yersinia translocate the protein tyrosine phosphatase YopH by a polarized mechanism into the target cellQ41493370
Translocation of a hybrid YopE-adenylate cyclase from Yersinia enterocolitica into HeLa cellsQ41497627
Pasteurella pestis: Role of Pesticin I and Iron in Experimental PlagueQ41562748
Helicobacter pylori initiates the stringent response upon nutrient and pH downshiftQ41672952
RelA-dependent (p)ppGpp production controls exoenzyme synthesis in Erwinia carotovora subsp. atrosepticaQ41762424
Identical, independent, and opposing roles of ppGpp and DksA in Escherichia coliQ41790469
Bacteria possessing two RelA/SpoT-like proteins have evolved a specific stringent response involving the acyl carrier protein-SpoT interaction.Q41831939
The molecular alarmone (p)ppGpp mediates stress responses, vancomycin tolerance, and virulence in Enterococcus faecalisQ41883007
The (p)ppGpp synthetase RelA contributes to stress adaptation and virulence in Enterococcus faecalis V583.Q42024610
Growth phase regulation of Vibrio cholerae RTX toxin exportQ42091298
The ObgE/CgtA GTPase influences the stringent response to amino acid starvation in Escherichia coli.Q42132307
SpoT-triggered stringent response controls usp gene expression in Pseudomonas aeruginosaQ42138905
Role for RpoS but not RelA of Legionella pneumophila in modulation of phagosome biogenesis and adaptation to the phagosomal microenvironmentQ42581941
Environmental regulation of Pseudomonas aeruginosa PAO1 Las and Rhl quorum-sensing systemsQ42617897
Transcription from bacteriophage lambda pR promoter is regulated independently and antagonistically by DksA and ppGppQ42637913
Growth phase and (p)ppGpp control of IraD, a regulator of RpoS stability, in Escherichia coliQ42688985
Polyphosphate kinase 1 is a pathogenesis determinant in Campylobacter jejuniQ42910189
Effective symbiosis between Rhizobium etli and Phaseolus vulgaris requires the alarmone ppGppQ42948948
Increased RNA polymerase availability directs resources towards growth at the expense of maintenance.Q43070072
Similar and divergent effects of ppGpp and DksA deficiencies on transcription in Escherichia coliQ43121907
The Campylobacter jejuni stringent response controls specific stress survival and virulence-associated phenotypes.Q43218720
RpoS co-operates with other factors to induce Legionella pneumophila virulence in the stationary phaseQ43636755
The Sinorhizobium meliloti stringent response affects multiple aspects of symbiosisQ43936762
A two-component regulator induces the transmission phenotype of stationary-phase Legionella pneumophila.Q43967545
The quormone degradation system of Agrobacterium tumefaciens is regulated by starvation signal and stress alarmone (p)ppGppQ44912246
The bacterial signal molecule, ppGpp, regulates Salmonella virulence gene expressionQ44928503
Differentiated Caco-2 cells as a model for enteric invasion by Campylobacter jejuni and C. coliQ45662045
Stringent response in Vibrio cholerae: genetic analysis of spoT gene function and identification of a novel (p)ppGpp synthetase gene.Q46082806
Identification of Streptococcus suis genes preferentially expressed under iron starvation by selective capture of transcribed sequencesQ46134262
Legionella pneumophila couples fatty acid flux to microbial differentiation and virulence.Q46146257
Metabolite and transcriptome analysis of Campylobacter jejuni in vitro growth reveals a stationary-phase physiological switch.Q46178029
Guanosine tetra- and pentaphosphate promote accumulation of inorganic polyphosphate in Escherichia coliQ46183930
Interaction of uropathogenic Escherichia coli with host uroepithelium.Q36032368
CodY, a global regulator of stationary phase and virulence in Gram-positive bacteriaQ36085281
Function of a relaxed-like state following temperature downshifts in Escherichia coliQ36112464
Microarray-based characterization of the Listeria monocytogenes cold regulon in log- and stationary-phase cellsQ36137182
Viable but nonculturable Vibrio cholerae O1 in biofilms in the aquatic environment and their role in cholera transmissionQ36140742
Shigella spp. and enteroinvasive Escherichia coli pathogenicity factorsQ36267084
Regulatory networks controlling Vibrio cholerae virulence gene expressionQ36313974
Response of Guanosine 5′-Triphosphate Concentration to Nutritional Changes and Its Significance for Bacillus subtilis SporulationQ36318019
New horizons for (p)ppGpp in bacterial and plant physiology.Q36339121
Francisella tularensis travels a novel, twisted road within macrophages.Q36342910
Legionella pneumophila replication vacuoles mature into acidic, endocytic organellesQ36369087
Virulent strains of Helicobacter pylori demonstrate delayed phagocytosis and stimulate homotypic phagosome fusion in macrophagesQ36375886
Campylobacter jejuni biofilms up-regulated in the absence of the stringent response utilize a calcofluor white-reactive polysaccharideQ36421827
DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirocheteQ34010197
Distinct roles of ppGpp and DksA in Legionella pneumophila differentiationQ34015737
Cloning of rel from Listeria monocytogenes as an osmotolerance involvement geneQ34052840
Latent Mycobacterium tuberculosis-persistence, patience, and winning by waitingQ34095048
Modulation of Borrelia burgdorferi stringent response and gene expression during extracellular growth with tick cellsQ34122177
Diverse phenotypes resulting from polyphosphate kinase gene (ppk1) inactivation in different strains of Helicobacter pyloriQ34124303
The role of pneumolysin in the pathogenesis of Streptococcus pneumoniae infectionQ34128823
Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modelingQ34161889
Environmental regulation and differential production of members of the Bdr protein family of Borrelia burgdorferiQ34258625
A Vibrio cholerae relaxed (relA) mutant expresses major virulence factors, exhibits biofilm formation and motility, and colonizes the suckling mouse intestineQ34303238
RelA protein is involved in induction of genetic competence in certain Bacillus subtilis strains by moderating the level of intracellular GTP.Q34314755
DksA affects ppGpp induction of RpoS at a translational levelQ34316573
The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cellQ34389221
ppGpp: a global regulator in Escherichia coli.Q34415352
Listeria monocytogenes relA and hpt mutants are impaired in surface-attached growth and virulenceQ34434579
Bacterial virulence, proinflammatory cytokines and host immunity: how to choose the appropriate Salmonella vaccine strain?Q34469798
Role of the Yersinia pestis plasminogen activator in the incidence of distinct septicemic and bubonic forms of flea-borne plagueQ34481674
Characterization of the stringent response and rel(Bbu) expression in Borrelia burgdorferiQ34514091
Association between virulence of Yersinia pestis and suppression of gamma interferon and tumor necrosis factor alpha.Q34520336
The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditionalQ34576115
Expression of spoT in Borrelia burgdorferi during serum starvationQ34580258
Sialosyl-galactose: a common denominator of Guillain-Barré and related disorders?Q34604677
A cold-sensitive Listeria monocytogenes mutant has a transposon insertion in a gene encoding a putative membrane protein and shows altered (p)ppGpp levelsQ34720772
In vitro conversion of Borrelia burgdorferi to cystic forms in spinal fluid, and transformation to mobile spirochetes by incubation in BSK-H mediumQ34748417
Quantitative proteomic analysis indicates increased synthesis of a quinolone by Pseudomonas aeruginosa isolates from cystic fibrosis airwaysQ34808489
The stringent response is required for Helicobacter pylori survival of stationary phase, exposure to acid, and aerobic shockQ34976634
Brucella intracellular life: from invasion to intracellular replicationQ34987707
Posttranscriptional control of quorum-sensing-dependent virulence genes by DksA in Pseudomonas aeruginosaQ35021121
Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniaeQ35111311
Mutation in the relA gene of Vibrio cholerae affects in vitro and in vivo expression of virulence factorsQ35171833
Organelle robbery: Brucella interactions with the endoplasmic reticulumQ35703097
Regulation of the stringent response is the essential function of the conserved bacterial G protein CgtA in Vibrio choleraeQ35721668
Differentiate to thrive: lessons from the Legionella pneumophila life cycle.Q35822038
Mutations in rpoBC suppress the defects of a Sinorhizobium meliloti relA mutantQ35921461
P433issue2
P304page(s)171-199
P577publication date2010-06-01
P1433published inMicrobiology and Molecular Biology ReviewsQ6839270
P1476titleppGpp conjures bacterial virulence
P478volume74

Reverse relations

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Q51751187High Nutrient Concentration Can Induce Virulence Factor Expression and Cause Higher Virulence in an Environmentally Transmitted Pathogen.
Q33668316Higher resource level promotes virulence in an environmentally transmitted bacterial fish pathogen.
Q39110335Hit the right spots: cell cycle control by phosphorylated guanosines in alphaproteobacteria
Q93031458How the initiating ribosome copes with ppGpp to translate mRNAs
Q92052166Identification of σE-Dependent Promoter Upstream of clpB from the Pathogenic Spirochaete Leptospira interrogans by Applying an E. coli Two-Plasmid System
Q48262631Impacts of feeding preweaned calves milk containing drug residues on the functional profile of the fecal microbiota
Q38386325Inactivation of Cell Division Protein FtsZ by SulA Makes Lon Indispensable for the Viability of a ppGpp0 Strain of Escherichia coli
Q35621955Insights into the CtrA regulon in development of stress resistance in obligatory intracellular pathogen Ehrlichia chaffeensis
Q38266910Interrelationship between type three secretion system and metabolism in pathogenic bacteria
Q90050542Intramolecular Interactions Dominate the Autoregulation of Escherichia coli Stringent Factor RelA
Q36628246Isothiocyanates as effective agents against enterohemorrhagic Escherichia coli: insight to the mode of action
Q30835451Low-level predation by lytic phage phiIPLA-RODI promotes biofilm formation and triggers the stringent response in Staphylococcus aureus.
Q93066265Make and break the alarmone: regulation of (p)ppGpp synthetase/hydrolase enzymes in bacteria
Q38326030Many means to a common end: the intricacies of (p)ppGpp metabolism and its control of bacterial homeostasis
Q35108239Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp
Q36269018Molecular mutagenesis of ppGpp: turning a RelA activator into an inhibitor
Q91030666Molecular regulatory mechanisms of Escherichia coli O157:H7 in response to ultrasonic stress revealed by proteomic analysis
Q34559184MudPIT profiling reveals a link between anaerobic metabolism and the alkaline adaptive response of Listeria monocytogenes EGD-e.
Q33556778Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA.
Q40285241Neisseria meningitidis Uses Sibling Small Regulatory RNAs To Switch from Cataplerotic to Anaplerotic Metabolism
Q47395522New Approaches and Therapeutic Options for Mycobacterium tuberculosis in a Dormant State
Q52671189Novel (p)ppGpp Binding and Metabolizing Proteins of Escherichia coli.
Q38047778Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP, (p)ppGpp signaling in bacteria and implications in pathogenesis.
Q92186804Optimised Synthesis of the Bacterial Magic Spot (p)ppGpp Chemosensor PyDPA
Q33623008Phenethyl isothiocyanate inhibits shiga toxin production in enterohemorrhagic Escherichia coli by stringent response induction
Q38645992Phenotypic and genetic heterogeneity within biofilms with particular emphasis on persistence and antimicrobial tolerance.
Q47381717Polyphosphate Kinase Antagonizes Virulence Gene Expression in Francisella tularensis.
Q58660854Proteome phenotyping of ΔrelA mutants in Enterococcus faecalis V583
Q91808034Proteomic and Metabolomic Analyses of a Tea-Tree Oil-Selected Staphylococcus aureus Small Colony Variant
Q33874096Pseudomonas aeruginosa cells attached to a surface display a typical proteome early as 20 minutes of incubation.
Q56761766RETRACTED: (p)ppGpp Controls Bacterial Persistence by Stochastic Induction of Toxin-Antitoxin Activity
Q64093394RSH Enzyme Synthesizes (p)ppGpp and pppApp and , and Leads to Discovery of pppApp Synthesis in
Q41909309Rapid nutritional remodeling of the host cell upon attachment of Legionella pneumophila
Q36319374Recent functional insights into the role of (p)ppGpp in bacterial physiology
Q30387100Redox-Active Sensing by Bacterial DksA Transcription Factors Is Determined by Cysteine and Zinc Content
Q57469398Region 3.2 of the σ factor controls the stability of rRNA promoter complexes and potentiates their repression by DksA
Q55040670Regulation of carbohydrate degradation pathways in Pseudomonas involves a versatile set of transcriptional regulators.
Q59341045Regulatory Hierarchies Controlling Virulence Gene Expression in and
Q37556629RelA Mutant Enterococcus faecium with Multiantibiotic Tolerance Arising in an Immunocompromised Host
Q41830351RelA inhibits Bacillus subtilis motility and chaining.
Q37152941Ribosome•RelA structures reveal the mechanism of stringent response activation.
Q35824119Role of (p)ppGpp in Viability and Biofilm Formation of Actinobacillus pleuropneumoniae S8.
Q36163108Role of RelA and SpoT in Burkholderia pseudomallei virulence and immunity
Q52730016Salmonella Reprograms Nucleotide Metabolism in Its Adaptation to Nitrosative Stress.
Q28821326Selective and Efficient Elimination of Vibrio cholerae with a Chemical Modulator that Targets Glucose Metabolism
Q50447715Selective and sensitive colorimetric detection of stringent alarmone ppGpp with Fenton-like reagent.
Q34299166Sigma S-dependent antioxidant defense protects stationary-phase Escherichia coli against the bactericidal antibiotic gentamicin.
Q37911547Signalling by the global regulatory molecule ppGpp in bacteria and chloroplasts of land plants.
Q55027412SpoT-Mediated Regulation and Amino Acid Prototrophy Are Essential for Pyocyanin Production During Parasitic Growth of Pseudomonas aeruginosa in a Co-culture Model System With Aeromonas hydrophila.
Q38595570Spontaneous and on point: Do spontaneous mutations used for laboratory experiments cause pleiotropic effects that might confound bacterial infection and evolution assays?
Q38648532Stress response regulators identified through genome-wide transcriptome analysis of the (p)ppGpp-dependent response in Rhizobium etli
Q54204493Stringent Response and AggR-Dependent Virulence Regulation in the Enteroaggregative Escherichia coli Strain 042.
Q42189268Stringent response regulation of biofilm formation in Vibrio cholerae
Q35978233Structural and Functional Analysis of BipA, a Regulator of Virulence in Enteropathogenic Escherichia coli
Q50078170Structural basis for (p)ppGpp synthesis by the Staphylococcus aureus small alarmone synthetase RelP.
Q40361184Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to β-Lactams.
Q36855117Surface display of a massively variable lipoprotein by a Legionella diversity-generating retroelement
Q89474628Synthesis of ppGpp impacts type IX secretion and biofilm matrix formation in Porphyromonas gingivalis
Q41986754Synthetic Peptides to Target Stringent Response-Controlled Virulence in a Pseudomonas aeruginosa Murine Cutaneous Infection Model
Q35025547Technologies and approaches to elucidate and model the virulence program of salmonella
Q48232558The Biochemistry of Sensing: Enteric Pathogens Regulate Type III Secretion in Response to Environmental and Host Cues.
Q35775775The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global Gene Expression during Starvation
Q90411042The C-Terminal RRM/ACT Domain Is Crucial for Fine-Tuning the Activation of 'Long' RelA-SpoT Homolog Enzymes by Ribosomal Complexes
Q37036014The Francisella tularensis migR, trmE, and cphA genes contribute to F. tularensis pathogenicity island gene regulation and intracellular growth by modulation of the stress alarmone ppGpp
Q49691558The Life Cycle of L. pneumophila: Cellular Differentiation Is Linked to Virulence and Metabolism
Q92589078The Link between Purine Metabolism and Production of Antibiotics in Streptomyces
Q27677778The Mechanism of E. coli RNA Polymerase Regulation by ppGpp Is Suggested by the Structure of their Complex
Q90716832The Ps and Qs of alarmone synthesis in Staphylococcus aureus
Q21135259The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life
Q36787486The RpoB H₄₈₁Y rifampicin resistance mutation and an active stringent response reduce virulence and increase resistance to innate immune responses in Staphylococcus aureus
Q63214066The Stringent Response Determines the Ability of a Commensal Bacterium to Survive Starvation and to Persist in the Gut
Q34129364The architecture and ppGpp-dependent expression of the primary transcriptome of Salmonella Typhimurium during invasion gene expression
Q35214799The bacterial alarmone (p)ppGpp activates the type III secretion system in Erwinia amylovora
Q36593406The bacterial alarmone (p)ppGpp is required for virulence and controls cell size and survival of Pseudomonas syringae on plants
Q35011996The dksA promoter is negatively feedback regulated by DksA and ppGpp
Q33779126The invA gene of Brucella melitensis is involved in intracellular invasion and is required to establish infection in a mouse model
Q36844041The magic spot: a ppGpp binding site on E. coli RNA polymerase responsible for regulation of transcription initiation
Q37955761The myriad roles of cyclic AMP in microbial pathogens: from signal to sword
Q100958417The nucleotide pGpp acts as a third alarmone in Bacillus, with functions distinct from those of (p) ppGpp
Q35130307The primary transcriptome of Salmonella enterica Serovar Typhimurium and its dependence on ppGpp during late stationary phase
Q27705295The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis
Q89280410The stringent response and Mycobacterium tuberculosis pathogenesis
Q101226653The stringent response and physiological roles of (pp)pGpp in bacteria
Q35273242The stringent response is essential for Pseudomonas aeruginosa virulence in the rat lung agar bead and Drosophila melanogaster feeding models of infection
Q34499356The stringent response of Staphylococcus aureus and its impact on survival after phagocytosis through the induction of intracellular PSMs expression.
Q28482089The two PPX-GppA homologues from Mycobacterium tuberculosis have distinct biochemical activities
Q34009865Tissue-specific Salmonella Typhimurium gene expression during persistence in pigs
Q35651084Transcriptional and Post-Transcriptional Modulation of SPI1 and SPI2 Expression by ppGpp, RpoS and DksA in Salmonella enterica sv Typhimurium
Q89664107Transcriptome analysis reveals that the RNA polymerase-binding protein DksA1 has pleiotropic functions in Pseudomonas aeruginosa
Q36340099Transcriptomic buffering of cryptic genetic variation contributes to meningococcal virulence
Q44597383Virulence in Pectobacterium atrosepticum is regulated by a coincidence circuit involving quorum sensing and the stress alarmone, (p)ppGpp
Q38619754Which microbial factors really are important in Pseudomonas aeruginosa infections?
Q42778159Whole genome transcriptomics reveals global effects including up-regulation of Francisella pathogenicity island gene expression during active stringent response in the highly virulent Francisella tularensis subsp. tularensis SCHU S4.
Q41930200Within and beyond the stringent response-RSH and (p)ppGpp in plants
Q42578226ppGpp Binding to a Site at the RNAP-DksA Interface Accounts for Its Dramatic Effects on Transcription Initiation during the Stringent Response
Q40170494ppGpp and cytotoxicity diversity in Shiga toxin-producing Escherichia coli (STEC) isolates.
Q82638365ppGpp inhibits peptide elongation cycle of chloroplast translation system in vitro
Q36015916ppGpp is the major source of growth rate control in E. coli
Q37984220ppGpp: magic beyond RNA polymerase
Q41353407rRNA regulation during growth and under stringent conditions in Staphylococcus aureus
Q35124312relA enhances the adherence of enteropathogenic Escherichia coli
Q89852981relA is Achilles' heel for mycobacterial pathogens as demonstrated with deletion mutants in Mycobacterium avium subsp. paratuberculosis and mycobacterium bovis bacillus Calmette-Guérin (BCG)

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