| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Fisher JW | |
| Lash LH | |||
| Lipscomb JC | |||
| Parker JC | |||
| P2860 | cites work | Metabolism of Tetrachloroethene in Rats: Identification of N.epsilon.-(Dichloroacetyl)-L-lysine and N.epsilon.-(Trichloroacetyl)-L-lysine as Protein Adducts | Q72110116 |
| [Interaction of trichloroethylene and isopropyl alcohol in the perfused rat liver] | Q72239842 | ||
| Roles of cysteine conjugate beta-lyase and S-oxidase in nephrotoxicity: studies with S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-L-cysteine sulfoxide | Q72389973 | ||
| Kinetics of interactions of para-aminohippurate, probenecid, cysteine conjugates and N-acetyl cysteine conjugates with basolateral organic anion transporter in isolated rabbit proximal renal tubules | Q72538347 | ||
| Cloning and characterization of a soluble kynurenine aminotransferase from rat brain: identity with kidney cysteine conjugate beta-lyase | Q72632363 | ||
| Cleavage of S-(1,2-dichlorovinyl)-l-cysteine by an enzyme of bovine origin | Q72645037 | ||
| Oxidation of cysteine S-conjugates by rabbit liver microsomes and cDNA-expressed flavin-containing mono-oxygenases: studies with S-(1,2-dichlorovinyl)-L-cysteine, S-(1,2,2-trichlorovinyl)-L-cysteine, S-allyl-L-cysteine, and S-benzyl-L-cysteine | Q73128226 | ||
| Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole glucuro | Q73599227 | ||
| Glutathione-dependent conversion to glyoxylate, a major pathway of dichloroacetate biotransformation in hepatic cytosol from humans and rats, is reduced in dichloroacetate-treated rats | Q73833558 | ||
| Na-dependent transport of S-(1,2-dichlorovinyl)-L-cysteine by renal brush-border membrane vesicles | Q74424803 | ||
| 1,1-Dichloroethylene-induced Clara cell damage is associated with in situ formation of the reactive epoxide. Immunohistochemical detection of its glutathione conjugate | Q77788898 | ||
| Renal cellular transport of exogenous glutathione: heterogeneity at physiological and pharmacological concentrations | Q78130874 | ||
| In vivo formation and localization of 1,1-dichloroethylene epoxide in murine liver: identification of its glutathione conjugate 2-S-glutathionyl acetate | Q78149419 | ||
| Isolation and characterization of a rat liver enzyme with both cysteine conjugate beta-lyase and kynureninase activity | Q93575714 | ||
| Cysteine conjugate beta-lyase activities in rat kidney cortex: subcellular localization and relationship to the hepatic enzyme | Q93590785 | ||
| Cytochrome P450-dependent metabolism of trichloroethylene: interindividual differences in humans | Q23915079 | ||
| Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid | Q24530743 | ||
| Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects | Q28322217 | ||
| A comparative study on the contribution of cytochrome P450 isozymes to metabolism of benzene, toluene and trichloroethylene in rat liver | Q28324626 | ||
| Cysteine conjugate beta-lyase in rat liver. A novel enzyme catalyzing formation of thiol-containing metabolites of drugs | Q28327924 | ||
| Purification and characterization of human hepatic cysteine-conjugate beta-lyase | Q28362067 | ||
| Identification of a mitochondrial form of kynurenine aminotransferase/glutamine transaminase K from rat brain | Q28569431 | ||
| Glutamine transaminase K and cysteine S-conjugate β-lyase activity stains | Q28581333 | ||
| Translocation of intracellular glutathione to membrane-bound γ-glutamyl transpeptidase as a discrete step in the γ-glutamyl cycle: Glutathionuria after inhibition of transpeptidase | Q28646487 | ||
| Extrapolation of in vitro enzyme induction data to humans in vivo | Q32174139 | ||
| THE METABOLISM OF 36C1-LABELLED TRICHLOROETHYLENE AND TETRACHLOROETHYLENE IN THE RAT. | Q33191469 | ||
| Dichloroacetic acid: metabolism in cytosol. | Q33485661 | ||
| Modes of action of trichloroethylene for kidney tumorigenesis | Q33916696 | ||
| Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetate | Q33916701 | ||
| Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment | Q33916714 | ||
| Exposure assessment of trichloroethylene | Q33916728 | ||
| Purification and characterization of human kidney cytosolic cysteine conjugate beta-lyase activity | Q34170358 | ||
| Cysteine S-conjugate N-acetyltransferase from rat kidney microsomes. | Q34272900 | ||
| Isolation from rat kidney of a cytosolic high molecular weight cysteine-S-conjugate beta-lyase with activity toward leukotriene E4. | Q34315433 | ||
| Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. | Q34330493 | ||
| Bioactivation mechanism of the cytotoxic and nephrotoxic S-conjugate S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine | Q34357210 | ||
| Nephrotoxic and genotoxic N-acetyl-S-dichlorovinyl-L-cysteine is a urinary metabolite after occupational 1,1,2-trichloroethene exposure in humans: implications for the risk of trichloroethene exposure | Q35031501 | ||
| The human hepatic cytochromes P450 involved in drug metabolism | Q36258518 | ||
| Isolation and expression of a cDNA coding for rat kidney cytosolic cysteine conjugate beta-lyase | Q36783923 | ||
| Consideration of the Target Organ Toxicity of Trichloroethylene in Terms of Metabolite Toxicity and Pharmacokinetics | Q37008371 | ||
| Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes | Q37362341 | ||
| Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P-450 of rabbit liver microsomes by diverse agents: ethanol, imidazole, trichloroethylene, acetone, pyrazole, and isoniazid | Q37691571 | ||
| Alteration of the enzymology of chloral hydrate reduction in the presence of ethanol | Q39299687 | ||
| Biotransformation of halogenated solvents | Q39835955 | ||
| Metabolism and kinetics of trichloroethylene in relation to toxicity and carcinogenicity. Relevance of the mercapturic acid pathway. | Q40498461 | ||
| Evaluating human variability in chemical risk assessment: hazard identification and dose-response assessment for noncancer oral toxicity of trichloroethylene | Q41035617 | ||
| A mechanism for the development of Clara cell lesions in the mouse lung after exposure to trichloroethylene | Q51685214 | ||
| Species differences in the metabolism of trichloroethylene to the carcinogenic metabolites trichloroacetate and dichloroacetate | Q51685443 | ||
| Sex-, age- and pregnancy-induced changes in the metabolism of toluene and trichloroethylene in rat liver in relation to the regulation of cytochrome P450IIE1 and P450IIC11 content | Q51689748 | ||
| Identification of N-acetyl(2,2-dichlorovinyl)- and N-acetyl(1,2-dichlorovinyl)-L-cysteine as two regioisomeric mercapturic acids of trichloroethylene in the rat. | Q51736177 | ||
| Metabolism of trichloroethene--in vivo and in vitro evidence for activation by glutathione conjugation. | Q51741878 | ||
| Physiologically based pharmacokinetic modeling of the pregnant rat: a multiroute exposure model for trichloroethylene and its metabolite, trichloroacetic acid. | Q51751604 | ||
| Pulmonary toxicity of trichloroethylene in mice. Covalent binding and morphological manifestations. | Q51761130 | ||
| Identification of S-1,2-dichlorovinyl-N-acetyl-cysteine as a urinary metabolite of trichloroethylene: a possible explanation for its nephrocarcinogenicity in male rats. | Q51805205 | ||
| Absorption, elimination and metabolism of trichloroethylene: a quantitative comparison between rats and mice. | Q51813418 | ||
| Species differences in response to trichloroethylene. I. Pharmacokinetics in rats and mice. | Q51824802 | ||
| Species differences in response to trichloroethylene. II. Biotransformation in rats and mice. | Q51825256 | ||
| Novel metabolites of trichloroethylene through dechlorination reactions in rats, mice and humans. | Q51841182 | ||
| Metabolism of trichloroethylene in isolated hepatocytes, microsomes, and reconstituted enzyme systems containing cytochrome P-450. | Q51855315 | ||
| Gas-chromatographic method for the halothane metabolites, trifluoroacetic acid and bromide, in biological fluids. | Q51874262 | ||
| Metabolism and lipoperoxidative activity of trichloroacetate and dichloroacetate in rats and mice | Q52416376 | ||
| Trichloroethylene exposure and trichloroethylene metabolites in urine and blood. | Q52735956 | ||
| Trichloroethylene toxicity; report of five fatal cases. | Q52777381 | ||
| In vivo and in vitro studies of perchloroethylene metabolism for physiologically based pharmacokinetic modeling in rats, mice, and humans. | Q53456953 | ||
| Interaction of chloral hydrate and ethanol in man: I. Metabolism | Q53834457 | ||
| Diminished CYP2E1 expression and formation of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1,1-dichloroethylene epoxide, in murine lung tumors. | Q54109263 | ||
| Further characterization and purification of the flavin-dependent S-benzyl-L-cysteine S-oxidase activities of rat liver and kidney microsomes. | Q54543528 | ||
| Kinetics and Metabolism of Chloral Hydrate in Children: Identification of Dichloroacetate as a Metabolite | Q59400108 | ||
| Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1 | Q67260608 | ||
| L-cysteine and S-(1,2-dichlorovinyl)-L-cysteine transport in rat liver canalicular membrane vesicles: potential reabsorption mechanisms for biliary metabolites of glutathione and its S-conjugates | Q68048159 | ||
| Perchloroethylene-induced rat kidney tumors: an investigation of the mechanisms involved and their relevance to humans | Q68084880 | ||
| Metabolism of hexafluoropropene. Evidence for bioactivation by glutathione conjugate formation in the kidney | Q68168372 | ||
| The role of mitochondrial matrix enzymes in the metabolism and toxicity of cysteine conjugates | Q68268542 | ||
| Metabolism of chloral hydrate in the anoxic perfused liver | Q68302391 | ||
| Mechanism of glutathione S-conjugate transport in canalicular and basolateral rat liver plasma membranes | Q68775325 | ||
| Mechanism of transport for toxic cysteine conjugates in rat kidney cortex membrane vesicles | Q69157270 | ||
| Renal cysteine conjugate beta-lyase. Bioactivation of nephrotoxic cysteine S-conjugates in mitochondrial outer membrane | Q69491628 | ||
| Transport and activation of S-(1,2-dichlorovinyl)-L-cysteine and N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine in rat kidney proximal tubules | Q69687543 | ||
| Alpha-ketoacids stimulate rat renal cysteine conjugate beta-lyase activity and potentiate the cytotoxicity of S-(1,2-dichlorovinyl)-L-cysteine | Q69732740 | ||
| N-acetyl S-(1,2-dichlorovinyl)-L-cysteine produces a similar toxicity to S-(1,2-dichlorovinyl)-L-cysteine in rabbit renal slices: differential transport and metabolism | Q69798166 | ||
| Direct evidence for the role of the membrane potential in glutathione transport by renal brush-border membranes | Q69855933 | ||
| Cytotoxicity of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine in isolated rat kidney cells | Q69887175 | ||
| Cysteine conjugate beta-lyase in the gastrointestinal bacterium Eubacterium limosum | Q70006651 | ||
| ATP-dependent S-(2,4-dinitrophenyl)glutathione transport in canalicular plasma membrane vesicles from rat liver | Q70231814 | ||
| Assay of cysteine conjugate beta-lyase activity with S-(2-benzothiazolyl)cysteine as the substrate | Q70390013 | ||
| Dose-dependent induction or depression of cysteine conjugate beta-lyase in rat kidney by N-acetyl-S-(1,2,3,4,4-pentachloro-1,3-butadienyl)-L-cysteine | Q70581988 | ||
| Comparative subcellular distribution of aldehyde dehydrogenase in rat, mouse and rabbit liver | Q70667391 | ||
| Renal processing of glutathione conjugates. Role in nephrotoxicity | Q70702534 | ||
| Antagonism of acute alcohol intoxication by naloxone | Q70800464 | ||
| Effect of vehicle on the pharmacokinetics and uptake of four halogenated hydrocarbons from the gastrointestinal tract of the rat | Q71169672 | ||
| CYP2E1-dependent bioactivation of 1,1-dichloroethylene in murine lung: formation of reactive intermediates and glutathione conjugates | Q71206037 | ||
| Purification and characterization of C-S lyase from Fusobacterium varium. A C-S cleavage enzyme of cysteine conjugates and some S-containing amino acids | Q71275777 | ||
| Biliary transport of glutathione S-conjugate by rat liver canalicular membrane vesicles | Q71327317 | ||
| Conversion of trichloroacetic acid to dichloroacetic acid in biological samples | Q71603357 | ||
| A species comparison of chloral hydrate metabolism in blood and liver | Q71700657 | ||
| Cysteine conjugate beta-lyase | Q71773691 | ||
| Formation of dichloroacetic acid by rat and mouse gut microflora, an in vitro study | Q71783606 | ||
| Pharmacokinetic analysis of chloral hydrate and its metabolism in B6C3F1 mice | Q71909427 | ||
| Bioactivation mechanism of cytotoxic homocysteine S-conjugates | Q41199096 | ||
| Mouse liver microsomal metabolism of chloral hydrate, trichloroacetic acid, and trichloroethanol leading to induction of lipid peroxidation via a free radical mechanism. | Q41248586 | ||
| Effect of ethanol on the metabolism of trichloroethylene | Q41282755 | ||
| Immunohistochemical localization of glutamine transaminase K, a rat kidney cysteine conjugate beta-lyase, and the relationship to the segment specificity of cysteine conjugate nephrotoxicity | Q41404719 | ||
| A pharmacokinetic model to study the excretion of trichloroethylene and its metabolites after an inhalation exposure | Q41407249 | ||
| Differences following skin or inhalation exposure in the absorption and excretion kinetics of trichloroethylene and toluene | Q41419082 | ||
| Glutathione S-conjugate transport by cultured human cells | Q41429577 | ||
| Cysteine conjugate beta-lyase of rat kidney cytosol: characterization, immunocytochemical localization, and correlation with hexachlorobutadiene nephrotoxicity | Q41949313 | ||
| Quantitation of multiple pathways for the metabolism of nephrotoxic cysteine conjugates using selective inhibitors of L-alpha-hydroxy acid oxidase (L-amino acid oxidase) and cysteine conjugate beta-lyase | Q42046069 | ||
| Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity | Q42201459 | ||
| Uptake of nephrotoxic S-conjugates by isolated rat renal proximal tubular cells | Q42203092 | ||
| Thioacylating intermediates as metabolites of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2,2-trichlorovinyl)-L-cysteine formed by cysteine conjugate beta-lyase | Q42204614 | ||
| A purified cysteine conjugate beta-lyase from rat kidney cytosol. Requirement for an alpha-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K. | Q42222923 | ||
| Renal glutathione transport. Characteristics of the sodium-dependent system in the basal-lateral membrane. | Q42458545 | ||
| Transport of glutathione by renal basal-lateral membrane vesicles | Q42464602 | ||
| Uptake of the glutathione conjugate S-(1,2-dichlorovinyl)glutathione by renal basal-lateral membrane vesicles and isolated kidney cells | Q42526873 | ||
| Influence of polymorphisms of GSTM1 and GSTT1 for risk of renal cell cancer in workers with long-term high occupational exposure to trichloroethene | Q42547835 | ||
| Cytochrome P450-related differences between rats and mice in the metabolism of benzene, toluene and trichloroethylene in liver microsomes | Q42558794 | ||
| Glutathione-degrading capacities of liver and kidney in different species | Q43566361 | ||
| Cysteine conjugate S-oxidase. Characterization of a novel enzymatic activity in rat hepatic and renal microsomes. | Q43728130 | ||
| Ethanol-induced enhancement of trichloroethylene metabolism and hepatotoxicity: difference from the effect of phenobarbital | Q43918493 | ||
| Metabolism of trichloroethylene in man. III. Interaction of trichloroethylene and ethanol | Q43986487 | ||
| Comparative metabolism of chloral hydrate and triclofos | Q44079130 | ||
| Reactivity of cysteine S-conjugate sulfoxides: formation of S-[1-chloro-2-(S-glutathionyl)vinyl]-L-cysteine sulfoxide by the reaction of S-(1,2-dichlorovinyl)-L-cysteine sulfoxide with glutathione | Q44094789 | ||
| Three forms of trichloroethylene-metabolizing enzymes in rat liver induced by ethanol, phenobarbital, and 3-methylcholanthrene | Q44303078 | ||
| In vivo metabolites of S-(2-benzothiazolyl)-L-cysteine as markers of in vivo cysteine conjugate beta-lyase and thiol glucuronosyl transferase activities | Q44557089 | ||
| Physiologically based pharmacokinetic modeling with trichloroethylene and its metabolite, trichloroacetic acid, in the rat and mouse | Q45139104 | ||
| Physiological pharmacokinetic modeling of inhaled trichloroethylene in rats | Q45184528 | ||
| Dermal absorption of dilute aqueous chloroform, trichloroethylene, and tetrachloroethylene in hairless guinea pigs | Q45939156 | ||
| Metabolism as a determinant of species susceptibility to 2,3,5-(triglutathion-S-yl)hydroquinone-mediated nephrotoxicity. The role of N-acetylation and N-deacetylation | Q46780695 | ||
| Glutamine transaminase K is not a major cysteine S-conjugate beta-lyase of rat kidney mitochondria: evidence that a high-molecular weight enzyme fulfills this role. | Q47345181 | ||
| Identification of S-(1,2-dichlorovinyl)glutathione in the blood of human volunteers exposed to trichloroethylene. | Q50537438 | ||
| A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol. | Q50852848 | ||
| Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes. | Q50871170 | ||
| Glutathione conjugation of trichloroethylene in rats and mice: sex-, species-, and tissue-dependent differences. | Q50911622 | ||
| Glutathione conjugation of trichloroethylene in human liver and kidney: kinetics and individual variation. | Q51472165 | ||
| In vitro to in vivo extrapolation for trichloroethylene metabolism in humans. | Q51485962 | ||
| Acute intoxication with trichloroethene: clinical symptoms, toxicokinetics, metabolism, and development of biochemical parameters for renal damage. | Q51519597 | ||
| Cysteine conjugate beta-lyase-dependent metabolism of compound A (2-[fluoromethoxy]-1,1,3,3,3-pentafluoro-1-propene) in human subjects anesthetized with sevoflurane and in rats given compound A. | Q51527147 | ||
| The role of mouse intestinal microflora in the metabolism of trichloroethylene, an in vivo study. | Q51532107 | ||
| A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice. | Q51534555 | ||
| Scaling factors to relate drug metabolic clearance in hepatic microsomes, isolated hepatocytes, and the intact liver: studies with induced livers involving diazepam. | Q51538005 | ||
| The role of glutathione conjugation in the development of kidney tumours in rats exposed to trichloroethylene. | Q51538850 | ||
| Trichloroethylene-induced mouse lung tumors: studies of the mode of action and comparisons between species. | Q51541042 | ||
| Characterization of presystemic elimination of trichloroethylene and its nonlinear kinetics in rats. | Q51565734 | ||
| Biotransformation of trichloroethene: dose-dependent excretion of 2,2,2-trichloro-metabolites and mercapturic acids in rats and humans after inhalation. | Q51580920 | ||
| Sulfoxidation of mercapturic acids derived from tri- and tetrachloroethene by cytochromes P450 3A: a bioactivation reaction in addition to deacetylation and cysteine conjugate beta-lyase mediated cleavage. | Q51581218 | ||
| Renal activation of trichloroethene and S-(1,2-dichlorovinyl)-L-cysteine and cell proliferative responses in the kidneys of F344 rats and B6C3F1 mice. | Q51587808 | ||
| Acid-labile adducts to protein can be used as indicators of the cysteine S-conjugate pathway of trichloroethene metabolism. | Q51587816 | ||
| Glutathione-dependent metabolism of trichloroethylene in isolated liver and kidney cells of rats and its role in mitochondrial and cellular toxicity. | Q51598546 | ||
| Factors affecting species differences in the kinetics of metabolites of trichloroethylene. | Q51607142 | ||
| Oral and intravenous trichloroethylene pharmacokinetics in the rat. | Q51639524 | ||
| Relative formation of dichloroacetate and trichloroacetate from trichloroethylene in male B6C3F1 mice. | Q51651749 | ||
| Pharmacokinetic modeling of trichloroethylene and trichloroacetic acid in humans. | Q51672021 | ||
| P921 | main subject | hazardous substances | Q757138 |
| hydrocarbon | Q43648 | ||
| P1104 | number of pages | 24 | |
| P304 | page(s) | 177-200 | |
| P577 | publication date | 2000-05-01 | |
| P1433 | published in | Environmental Health Perspectives | Q1345904 |
| P1476 | title | Metabolism of trichloroethylene | |
| P478 | volume | 108 Suppl 2 |
| Q47254105 | A framework and case studies for evaluation of enzyme ontogeny in children's health risk evaluation |
| Q28391997 | A task-based assessment of parental occupational exposure to organic solvents and other compounds and the risk of childhood leukemia in California |
| Q46287411 | Ability of trichloroethylene metabolite to promote immune pathology is strain-specific |
| Q37176028 | Adverse drug reactions with halogenated anesthetics |
| Q39321779 | Altered expression of hepatic metabolic enzyme and apoptosis-related gene transcripts in human hepatocytes treated with trichloroethylene. |
| Q42361925 | Ameliorative effect of vitamin E on trichloroethylene-induced nephrotoxicity in rats. |
| Q46981486 | An example of model structure differences using sensitivity analyses in physiologically based pharmacokinetic models of trichloroethylene in humans |
| Q48248611 | Analysis of gene expression profile of Arabidopsis genes under trichloroethylene stresses with the use of a full-length cDNA microarray |
| Q48114188 | Assessment of the immunotoxic potential of trichloroethylene and perchloroethylene in rats following inhalation exposure |
| Q36281313 | Basic studies on epigenetic carcinogenesis of low-dose exposure to 1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline (TaClo) in vitro. |
| Q47225856 | Characterization of inter-tissue and inter-strain variability of TCE glutathione conjugation metabolites DCVG, DCVC, and NAcDCVC in the mouse |
| Q43823605 | Chloral hydrate for progressive myoclonus epilepsy: a new look at an old drug |
| Q35684236 | Chloral hydrate, through biotransformation to dichloroacetate, inhibits maleylacetoacetate isomerase and tyrosine catabolism in humans |
| Q46196640 | Comments on "Lifetime exposure to trichloroethylene (TCE) does not accelerate autoimmune disease in MRL+/- mice |
| Q90573663 | Comparative analysis of metabolism of trichloroethylene and tetrachloroethylene among mouse tissues and strains |
| Q34802950 | Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects |
| Q40814711 | Complement C5a-C5aR interaction enhances MAPK signaling pathway activities to mediate renal injury in trichloroethylene sensitized BALB/c mice |
| Q30520640 | Contributions of human enzymes in carcinogen metabolism |
| Q91971549 | Detection of Organohalide-Respiring Enzyme Biomarkers at a Bioaugmented TCE-Contaminated Field Site |
| Q36953603 | Detection of multiple globin monoadducts and cross-links after in vitro exposure of rat erythrocytes to S-(1,2-dichlorovinyl)-L-cysteine sulfoxide and after in vivo treatment of rats with S-(1,2-dichlorovinyl)-L-cysteine sulfoxide |
| Q35653419 | Differential expression profile of membrane proteins in L-02 cells exposed to trichloroethylene |
| Q34282835 | Differential response to trichloroethylene-induced hepatosteatosis in wild-type and PPARalpha-humanized mice |
| Q92143811 | Differential toxicity of water versus gavage exposure to trichloroethylene in rats |
| Q44755425 | Diosmin protects against trichloroethylene-induced renal injury in Wistar rats: plausible role of p53, Bax and caspases |
| Q34710236 | Do Antioxidant Enzymes and Glutathione Play Roles in the Induction of Hepatic Oxidative Stress in Mice upon Subchronic Exposure to Mixtures of Dichloroacetate and Trichloroacetate? |
| Q47647738 | Does occupational exposure to anesthetic gases lead to increase of pro-inflammatory cytokines? |
| Q33916723 | Dose-response analyses of the carcinogenic effects of trichloroethylene in experimental animals |
| Q44871446 | Editor's Highlight: Collaborative Cross Mouse Population Enables Refinements to Characterization of the Variability in Toxicokinetics of Trichloroethylene and Provides Genetic Evidence for the Role of PPAR Pathway in Its Oxidative Metabolism. |
| Q46777600 | Editor's Highlight: High-Throughput Functional Genomics Identifies Modulators of TCE Metabolite Genotoxicity and Candidate Susceptibility Genes |
| Q48128879 | Effects of chlorinated acetates on the glutathione metabolism and on glycolysis of cultured astrocytes |
| Q41703647 | Epigenetic Toxicity of Trichloroethylene: A Single-Molecule Perspective |
| Q35024790 | Evaluating pharmacokinetic and pharmacodynamic interactions with computational models in supporting cumulative risk assessment |
| Q44425052 | Evidence for Trichloroethylene Bioactivation and Adduct Formation in the Rat Epididymis and Efferent Ducts1 |
| Q38285787 | Evidence for the use of isoflurane as a replacement for chloral hydrate anesthesia in experimental stroke: an ethical issue |
| Q37201162 | Evidence of autoimmune-related effects of trichloroethylene exposure from studies in mice and humans |
| Q43851733 | Expression of functional mammalian P450 2E1 in hairy root cultures |
| Q37106911 | Follow-up assessment of two cases of trichloroethylene hypersensitivity syndrome: A case report |
| Q34109552 | Genetic loci influencing kidney function and chronic kidney disease |
| Q37070978 | Genetic signature for human risk assessment: lessons from trichloroethylene |
| Q26801059 | Genotoxicity of Anesthetics Evaluated In Vivo (Animals) |
| Q42715468 | Glutathione-dependent bioactivation |
| Q47701705 | Hesperidin ameliorates trichloroethylene-induced nephrotoxicity by abrogation of oxidative stress and apoptosis in wistar rats. |
| Q44447126 | High pressure liquid chromatography and mass spectrometry characterization of the nephrotoxic biotransformation products of Cisplatin. |
| Q37401192 | High-resolution metabolomics of occupational exposure to trichloroethylene |
| Q26825606 | Human health effects of trichloroethylene: key findings and scientific issues |
| Q37206708 | Human polymorphisms in the glutathione transferase zeta 1/maleylacetoacetate isomerase gene influence the toxicokinetics of dichloroacetate |
| Q33916686 | Human variability and susceptibility to trichloroethylene |
| Q46287362 | Immuno- and hepato-toxicity of dichloroacetic acid in MRL(+/+) and B(6)C(3)F(1) mice |
| Q34496435 | Impact of trichloroethylene exposure on the microbial diversity and protein expression in anaerobic granular biomass at 37°C and 15°C. |
| Q24810937 | In silico toxicology: simulating interaction thresholds for human exposure to mixtures of trichloroethylene, tetrachloroethylene, and 1,1,1-trichloroethane |
| Q57595230 | Industrial Chemicals |
| Q30308411 | Inhibition of gamma-glutamyl transpeptidase or cysteine S-conjugate beta-lyase activity blocks the nephrotoxicity of cisplatin in mice |
| Q36054933 | Interactive toxicity of inorganic mercury and trichloroethylene in rat and human proximal tubules: effects on apoptosis, necrosis, and glutathione status |
| Q34601385 | Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice |
| Q35039326 | Issues in the pharmacokinetics of trichloroethylene and its metabolites |
| Q35039295 | Key scientific issues in the health risk assessment of trichloroethylene |
| Q43178457 | Lack of formic acid production in rat hepatocytes and human renal proximal tubule cells exposed to chloral hydrate or trichloroacetic acid |
| Q42504760 | Lack of trigeminal nerve toxicity in rats exposed to trichloroethylene vapor for 13 weeks |
| Q37396395 | Liquid chromatography electrospray ionization tandem mass spectrometry analysis method for simultaneous detection of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine |
| Q63951674 | Long-Term Combinatorial Exposure to Trichloroethylene and Inorganic Arsenic in Genetically Heterogeneous Mice Results in Renal Tubular Damage and Cancer-Associated Molecular Changes. |
| Q37590712 | Low-dose trichloroethylene alters cytochrome P450-2C subfamily expression in the developing chick heart |
| Q28256111 | Mechanistic considerations for human relevance of cancer hazard of di(2-ethylhexyl) phthalate |
| Q89088585 | Metabolism and Toxicity of Trichloroethylene and Tetrachloroethylene in Cytochrome P450 2E1 Knockout and Humanized Transgenic Mice |
| Q34657985 | Metabolism and tissue distribution of orally administered trichloroethylene in male and female rats: identification of glutathione- and cytochrome P-450-derived metabolites in liver, kidney, blood, and urine |
| Q38976985 | Metabolism of the soil and groundwater contaminants, ethylene dibromide and trichloroethylene, by the tropical leguminous tree, Leuceana leucocephala. |
| Q42715467 | Methods for measuring cysteine S-conjugate β-lyase activity |
| Q33916701 | Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetate |
| Q33916696 | Modes of action of trichloroethylene for kidney tumorigenesis |
| Q35990446 | Modulation of hepatic and renal metabolism and toxicity of trichloroethylene and perchloroethylene by alterations in status of cytochrome P450 and glutathione. |
| Q36781326 | Mutagenicity of the cysteine S-conjugate sulfoxides of trichloroethylene and tetrachloroethylene in the Ames test |
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