Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells

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Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells is …
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scholarly articleQ13442814

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P819ADS bibcode2010PNAS..10710696D
P356DOI10.1073/PNAS.1004882107
P932PMC publication ID2890792
P698PubMed publication ID20498071
P5875ResearchGate publication ID44626117

P50authorDavid HockenberyQ110718522
Patrick CarrollQ43183467
P2093author name stringMichael Lagunoff
Tracie Delgado
Daciana Margineantu
Almira S Punjabi
P2860cites workSelective down-regulation of human papillomavirus transcription by 2-deoxyglucoseQ48017824
Effect of oxamate on glycolysis and respiration in sarcoma 37 ascites cellsQ72223285
Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondriaQ24595940
Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapyQ24646296
Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1Q24681460
Cancer cell metabolism: Warburg and beyondQ28293198
HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxiaQ28300406
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumptionQ28300415
Dynamics of the cellular metabolome during human cytomegalovirus infectionQ28469080
On respiratory impairment in cancer cellsQ29617276
Akt stimulates aerobic glycolysis in cancer cellsQ29619301
Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurementsQ33771214
Glycolysis during early infection of feline and human cells with feline leukemia virus.Q34107557
Establishment and maintenance of Kaposi's sarcoma-associated herpesvirus latency in B cellsQ34124015
Sirolimus for Kaposi's sarcoma in renal-transplant recipientsQ34556363
Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors.Q34768392
Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) epidemiology and pathogenesisQ35026060
Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factorsQ35139228
Persistent activation of STAT3 by latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells.Q35784707
Sugar and fat - that's where it's at: metabolic changes in tumorsQ36643052
Activation of Akt through gp130 receptor signaling is required for Kaposi's sarcoma-associated herpesvirus-induced lymphatic reprogramming of endothelial cellsQ36845797
Hypoxic regulation of glucose transport, anaerobic metabolism and angiogenesis in cancer: novel pathways and targets for anticancer therapeuticsQ36862390
Mitochondria in cancer cells: what is so special about them?Q37093125
Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype.Q37325401
De novo infection and serial transmission of Kaposi's sarcoma-associated herpesvirus in cultured endothelial cellsQ39748116
Tumor metabolism: cancer cells give and take lactateQ39912324
2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancerQ40021272
Kaposi's sarcoma-associated herpesvirus induces sustained NF-kappaB activation during de novo infection of primary human dermal microvascular endothelial cells that is essential for viral gene expressionQ40173444
Kaposi's sarcoma-associated herpesvirus confers a survival advantage to endothelial cellsQ42141115
Hypersensitization of tumor cells to glycolytic inhibitorsQ43593851
Glycolysis in chick embryo cell cultures transformed by Rous sarcoma virusQ45823721
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
Kaposi's sarcomaQ725345
P1104number of pages6
P304page(s)10696-10701
P577publication date2010-05-24
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleInduction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells
P478volume107

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