A viral kinase mimics S6 kinase to enhance cell proliferation

scientific article published on 24 June 2016

A viral kinase mimics S6 kinase to enhance cell proliferation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1073/PNAS.1600587113
P932PMC publication ID4948314
P698PubMed publication ID27342859

P50authorBlossom DamaniaQ27921691
Kurtis M HostQ74932861
P2093author name stringHsing-Jien Kung
Brenda R S Temple
Marc S Weinberg
Yoshihiro Izumiya
Aadra Prashant Bhatt
Evert van Dijk
Jason P Wong
Joshua Buijnink
Louise C Giffin
P2860cites workThe mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activityQ24293101
The protein kinase complement of the human genomeQ24324497
The HHpred interactive server for protein homology detection and structure predictionQ24530456
Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signalingQ24673299
KSHV: pathways to tumorigenesis and persistent infectionQ27026000
Structural Basis of Human p70 Ribosomal S6 Kinase-1 Regulation by Activation Loop PhosphorylationQ27658004
eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translationQ27860920
Assessment of protein models with three-dimensional profilesQ28283805
Role of PFKFB3-driven glycolysis in vessel sproutingQ28295875
Topics in herpesvirus genomics and evolutionQ28298372
Cyclin-dependent kinase-like function is shared by the beta- and gamma- subset of the conserved herpesvirus protein kinasesQ28475457
S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage responseQ28509658
Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic SignalingQ28551996
Molecular mechanisms of mTOR-mediated translational controlQ29615529
Comparative protein structure modeling using MODELLERQ29617493
Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/mTOR-addicted lymphomasQ33896731
Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cellsQ33934809
Genetic organization and hypoxic activation of the Kaposi's sarcoma-associated herpesvirus ORF34-37 gene clusterQ34717873
Protein kinases conserved in herpesviruses potentially share a function mimicking the cellular protein kinase cdc2.Q35204267
The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile.Q35216878
Kaposi's sarcoma-associated herpesvirus-encoded protein kinase and its interaction with K-bZIP.Q35635192
Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication.Q35660314
Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphomaQ36122839
Functions and regulation of the 70kDa ribosomal S6 kinases.Q37798912
Upregulation of the TLR3 pathway by Kaposi's sarcoma-associated herpesvirus during primary infectionQ38610318
Targeted inhibition of mTORC2 prevents osteosarcoma cell migration and promotes apoptosisQ38993838
Targeting of mTORC2 prevents cell migration and promotes apoptosis in breast cancer.Q39369234
Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: maintenance of tight latency with efficient reactivation upon inductionQ39573744
Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinasesQ39663675
Inhibitor hijacking of Akt activationQ39847621
Phosphorylation of retinoblastoma protein by viral protein with cyclin-dependent kinase function.Q39984081
Hypoxia enhances the phosphorylation and cytotoxicity of ganciclovir and zidovudine in Kaposi's sarcoma-associated herpesvirus infected cellsQ40105402
ORF36 protein kinase of Kaposi's sarcoma herpesvirus activates the c-Jun N-terminal kinase signaling pathway.Q40537026
Conserved herpesviral kinase promotes viral persistence by inhibiting the IRF-3-mediated type I interferon responseQ41810499
Kaposi's sarcoma-associated herpesvirus confers a survival advantage to endothelial cellsQ42141115
Tousled-like kinases modulate reactivation of gammaherpesviruses from latencyQ42274743
Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) open reading frame 36 protein is a serine protein kinaseQ42622023
Kinome profiling for studying lipopolysaccharide signal transduction in human peripheral blood mononuclear cellsQ45050498
The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) K1 protein induces expression of angiogenic and invasion factorsQ47755368
P433issue28
P407language of work or nameEnglishQ1860
P304page(s)7876-7881
P577publication date2016-06-24
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleA viral kinase mimics S6 kinase to enhance cell proliferation
P478volume113

Reverse relations

cites work (P2860)
Q54111927Human herpesvirus-encoded kinase induces B cell lymphomas in vivo.
Q92340148In Vivo Models of Oncoproteins Encoded by Kaposi's Sarcoma-Associated Herpesvirus
Q94012444Kaposi sarcoma
Q91876872Kaposi sarcoma-associated herpesvirus miRNAs suppress CASTOR1-mediated mTORC1 inhibition to promote tumorigenesis
Q38943741Kaposi sarcoma-associated herpesvirus: immunobiology, oncogenesis, and therapy
Q92376588Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication Interferes with mTORC1 Regulation of Autophagy and Viral Protein Synthesis
Q58585811Lysosome membrane permeabilization and disruption of mTOR-lysosome interaction are associated with the inhibition of lung cancer cell proliferation by a chloroquinoline analog
Q92238951Modulation of Angiogenic Processes by the Human Gammaherpesviruses, Epstein-Barr Virus and Kaposi's Sarcoma-Associated Herpesvirus
Q39173806Modulation of oncogenic signaling networks by Kaposi's sarcoma-associated herpesvirus
Q64258880Targeting mTOR with MLN0128 Overcomes Rapamycin and Chemoresistant Primary Effusion Lymphoma

Search more.