Endoplasmic reticulum stress links hepatitis C virus RNA replication to wild-type PGC-1α/liver-specific PGC-1α upregulation

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Endoplasmic reticulum stress links hepatitis C virus RNA replication to wild-type PGC-1α/liver-specific PGC-1α upregulation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.01202-14
P932PMC publication ID4135942
P698PubMed publication ID24829353
P5875ResearchGate publication ID262340961

P50authorLongbo HuQ58072595
P2093author name stringTao Peng
Ting Li
Hua Cai
Wenxia Yao
Xinlei Li
P2860cites workHepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathwayQ24537844
PGC-1 coactivators: inducible regulators of energy metabolism in health and diseaseQ24541524
Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-IQ24556673
ER stress-induced cell death mechanismsQ27027638
Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimerasQ27473179
Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein responseQ27487012
Virus-induced over-expression of protein phosphatase 2A inhibits insulin signalling in chronic hepatitis C.Q39981071
Hepatitis C virus, ER stress, and oxidative stressQ40432170
Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR.Q40667994
Sustained virological response prevents the development of insulin resistance in patients with chronic hepatitis C.Q42980606
Activation of endoplasmic reticulum stress response by hepatitis viruses up-regulates protein phosphatase 2A.Q43037981
In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C.Q44332232
Herpes simplex virus type 1 infection activates the Epstein-Barr virus replicative cycle via a CREB-dependent mechanismQ45360917
p38 Mitogen-activated protein kinase mediates free fatty acid-induced gluconeogenesis in hepatocytes.Q53594219
HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA MiceQ27487963
Efficient initiation of HCV RNA replication in cell cultureQ27860520
A system for stable expression of short interfering RNAs in mammalian cellsQ27860875
Complete replication of hepatitis C virus in cell cultureQ27860934
Replication of hepatitis C virusQ27860957
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1Q28216275
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase BQ28638147
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1Q29615692
Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalenceQ29616009
Metabolic control through the PGC-1 family of transcription coactivatorsQ29616509
Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated, FoxO1-dependent pathwayQ30395512
p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesisQ33226681
Peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) stimulates VLDL assembly through activation of cell death-inducing DFFA-like effector B (CideB)Q34074263
The use of animal models in diabetes researchQ34255921
Hepatocyte nuclear factor 4α and downstream secreted phospholipase A2 GXIIB regulate production of infectious hepatitis C virusQ34381310
Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitroQ34428880
Influence of molecular and chemical chaperones on protein foldingQ34432453
Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesisQ34920348
An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscleQ35163135
Characterization of novel peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) isoform in human liver.Q35604515
Endoplasmic reticulum stress in liver diseaseQ36031838
Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword?Q36989869
Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscleQ36998996
Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolismQ37006469
Global control of hepatitis C: where challenge meets opportunityQ37077112
Hepatitis C infection and risk of diabetes: a systematic review and meta-analysisQ37097794
The biology of PGC-1α and its therapeutic potentialQ37484604
Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases.Q37804462
Assembly of infectious hepatitis C virus particlesQ37819269
Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesisQ37834857
Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagyQ39241528
Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell cultureQ39302599
The metabolic regulator PGC-1α links hepatitis C virus infection to hepatic insulin resistance.Q39325440
Novel mutations in a tissue culture-adapted hepatitis C virus strain improve infectious-virus stability and markedly enhance infection kineticsQ39598862
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectendoplasmic reticulumQ79927
hepatitis CQ154869
Hepatitis C virusQ708693
P304page(s)8361-8374
P577publication date2014-05-14
P1433published inJournal of VirologyQ1251128
P1476titleEndoplasmic reticulum stress links hepatitis C virus RNA replication to wild-type PGC-1α/liver-specific PGC-1α upregulation
P478volume88

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cites work (P2860)
Q58603892Aberrant expression of alternative isoforms of transcription factors in hepatocellular carcinoma
Q57149436Association between MicroRNA-373 and Long Noncoding RNA NORAD in Hepatitis C Virus-Infected Hepatocytes Impairs Wee1 Expression for Growth Promotion
Q27469080Cell-death-inducing DFFA-like Effector B Contributes to the Assembly of Hepatitis C Virus (HCV) Particles and Interacts with HCV NS5A
Q38402247Cellular stress responses in hepatitis C virus infection: Mastering a two-edged sword
Q26996778HCV and Oxidative Stress: Implications for HCV Life Cycle and HCV-Associated Pathogenesis
Q26751755Hepatitis C Virus, Insulin Resistance, and Steatosis
Q92607293Hepatitis C virus core or NS3/4A protein expression preconditions hepatocytes against oxidative stress and endoplasmic reticulum stress
Q58723536Host phosphatidic acid phosphatase lipin1 is rate limiting for functional hepatitis C virus replicase complex formation
Q90193411Liraglutide Inhibits Hepatitis C Virus Replication Through an AMP Activated Protein Kinase Dependent Mechanism
Q36227134Look who's talking-the crosstalk between oxidative stress and autophagy supports exosomal-dependent release of HCV particles
Q26773198Mechanisms of intrahepatic triglyceride accumulation
Q26773261Metabolic alterations and hepatitis C: From bench to bedside
Q37174380Nonstructural 3 Protein of Hepatitis C Virus Modulates the Tribbles Homolog 3/Akt Signaling Pathway for Persistent Viral Infection
Q26752335PGC-1α, glucose metabolism and type 2 diabetes mellitus
Q46421404Propofol attenuates H2O2-induced oxidative stress and apoptosis via the mitochondria- and ER-medicated pathways in neonatal rat cardiomyocytes
Q40112761Role of HDAC9-FoxO1 Axis in the Transcriptional Program Associated with Hepatic Gluconeogenesis.
Q89896008The Role of PGC-1α and Mitochondrial Biogenesis in Kidney Diseases
Q90836373The cellular stress response in hepatitis C virus infection: A balancing act to promote viral persistence and host cell survival

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