Liver and muscle in morbid obesity: the interplay of fatty liver and insulin resistance.

scientific article

Liver and muscle in morbid obesity: the interplay of fatty liver and insulin resistance. is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2012PLoSO...731738M
P356DOI10.1371/JOURNAL.PONE.0031738
P932PMC publication ID3281005
P698PubMed publication ID22359625
P5875ResearchGate publication ID221856118

P50authorCecília RodriguesQ30421070
Helena Cortez-PintoQ43042720
Rui E. CastroQ43087499
P2093author name stringTeresinha Evangelista
João Coutinho
Mariana Verdelho Machado
Adília Costa
Duarte M S Ferreira
Fátima Carepa
Ana Rita Silvestre
P2860cites workHomeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in manQ26776977
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final reportQ27861020
Design and validation of a histological scoring system for nonalcoholic fatty liver diseaseQ29614930
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetesQ29616567
Long-term follow-up of patients with NAFLD and elevated liver enzymesQ29620024
Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitisQ30448524
Aberrant mitochondrial homeostasis in the skeletal muscle of sedentary older adultsQ33592857
Impaired regulation of the TNF-alpha converting enzyme/tissue inhibitor of metalloproteinase 3 proteolytic system in skeletal muscle of obese type 2 diabetic patients: a new mechanism of insulin resistance in humansQ33755056
Pathogenesis of insulin resistance in skeletal muscleQ33812448
Effects of intravenous and dietary lipid challenge on intramyocellular lipid content and the relation with insulin sensitivity in humansQ34099337
Lipid-induced insulin resistance: unravelling the mechanismQ34370958
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in miceQ35108391
Follow-up report on the diagnosis of diabetes mellitusQ35567871
Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance.Q35785726
High-fat diets cause insulin resistance despite an increase in muscle mitochondriaQ36693972
Muscle insulin resistance: a case of fat overconsumption, not mitochondrial dysfunctionQ36693993
Lipid mediators of insulin resistanceQ36867145
Lipid accumulation in non-adipose tissue and lipotoxicityQ37068180
Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitusQ37141727
Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscleQ37175187
Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide.Q37246341
PGC-1alpha-mediated regulation of gene expression and metabolism: implications for nutrition and exercise prescriptionsQ37299286
Regulation of skeletal muscle mitochondrial fatty acid metabolism in lean and obese individualsQ37341267
The role of adiponectin in the pathogenesis and treatment of non-alcoholic fatty liver diseaseQ37736540
Serum total adiponectin in nonalcoholic fatty liver disease: a systematic review and meta-analysis.Q37805851
Obesity-associated insulin resistance in skeletal muscle: role of lipid accumulation and physical inactivity.Q37845219
Intramuscular lipid content is increased in obesity and decreased by weight lossQ39535127
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells.Q40818302
Ceramide content is increased in skeletal muscle from obese insulin-resistant humansQ42454790
Chronological approach of diet-induced alterations in muscle mitochondrial functions in rats.Q51480723
Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle.Q51554321
Age-related fat deposition in multifidus muscle could be a marker for nonalcoholic fatty liver disease.Q51605806
Apoptosis and insulin resistance in liver and peripheral tissues of morbidly obese patients is associated with different stages of non-alcoholic fatty liver disease.Q54599587
Excess Lipid Availability Increases Mitochondrial Fatty Acid Oxidative Capacity in MuscleQ54986901
Apoptosis and Bcl-2 expression in the livers of patients with steatohepatitisQ57760188
A position statement on NAFLD/NASH based on the EASL 2009 special conferenceQ61338101
Skeletal Muscle Lipogenic Protein Expression Is Not Different between Lean and Obese Individuals: A Potential Factor in Ceramide AccumulationQ63805149
Gastrointestinal surgery for severe obesity: National Institutes of Health Consensus Development Conference StatementQ67735595
Lipid oxidation is reduced in obese human skeletal muscleQ73127280
Mitochondrial function: use it or lose itQ79721968
Pathologic criteria for nonalcoholic steatohepatitis: interprotocol agreement and ability to predict liver-related mortalityQ83500394
Lifelong physical activity modulation of the skeletal muscle mitochondrial proteome in mice.Q43049782
Increased tumor necrosis factor alpha-converting enzyme activity induces insulin resistance and hepatosteatosis in mice.Q43251946
Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: relationships to insulin sensitivity, total body fat, and central adiposityQ43935425
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscleQ43990155
Normal insulin sensitivity and IMCL content in overweight humans are associated with higher fasting lipid oxidationQ44095719
Intramyocellular lipid and insulin resistance: a longitudinal in vivo 1H-spectroscopic study in Zucker diabetic fatty ratsQ44262550
Skeletal muscle lipid metabolism with obesityQ44355154
Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndromeQ44385945
Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivityQ44392926
Muscle fat oxidative capacity is not impaired by age but by physical inactivity: association with insulin sensitivity.Q44772657
Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in miceQ46232844
Plasma adiponectin in nonalcoholic fatty liver is related to hepatic insulin resistance and hepatic fat content, not to liver disease severityQ46410788
Distinct effects of aerobic exercise training and weight loss on glucose homeostasis in obese sedentary men.Q47328770
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectobesityQ12174
insulin resistanceQ1053470
morbid obesityQ9051491
P304page(s)e31738
P577publication date2012-02-16
P1433published inPLOS OneQ564954
P1476titleLiver and muscle in morbid obesity: the interplay of fatty liver and insulin resistance
P478volume7

Reverse relations

cites work (P2860)
Q58582579ATP Production of Muscle Mitochondria after Acute Exercise in Lean and Obese Humans
Q60922887Can obesity-induced inflammation in skeletal muscle and intramuscular adipose tissue accurately detect liver fibrosis?
Q36687279Cardiovascular risk escalation with caloric excess: a prospective demonstration of the mechanics in healthy adults
Q33844787Developmental origins of nonalcoholic fatty liver disease
Q37629154Dissociation of hepatic insulin resistance from susceptibility of nonalcoholic fatty liver disease induced by a high-fat and high-carbohydrate diet in mice.
Q56967616Ectopic lipid storage in non-alcoholic fatty liver disease is not mediated by impaired mitochondrial oxidative capacity in skeletal muscle
Q61452212Effects of liver function, insulin resistance and inflammatory factors on vascular endothelial dilation function and prognosis of coronary heart disease patients complicated with NAFLD
Q51835057Metabolic adaptations to HFHS overfeeding: how whole body and tissues postprandial metabolic flexibility adapt in Yucatan mini-pigs.
Q38113765Mitochondria: sensors and mediators of innate immune receptor signaling.
Q37670352Mitochondrial-related proteomic changes during obesity and fasting in mice are greater in the liver than skeletal muscles
Q50238978Muscle-specific deletion of signal transducer and activator of transcription 5 augments lipid accumulation in skeletal muscle and liver of mice in response to high-fat diet.
Q37002532Non-alcoholic fatty liver disease (NAFLD) and its connection with insulin resistance, dyslipidemia, atherosclerosis and coronary heart disease
Q64052598Non-alcoholic fatty liver disease and pregnancy complications among Sri Lankan women: A cross sectional analytical study
Q24563068Non-alcoholic fatty liver disease: what the clinician needs to know
Q91727581Obesity modifies the stoichiometry of mitochondrial proteins in a way that is distinct to the subcellular localization of the mitochondria in skeletal muscle
Q47745065Plasma Amino Acids Stimulate Uncoupled Respiration of Muscle Subsarcolemmal Mitochondria in Lean but Not Obese Humans
Q38202220Revisiting the metabolic syndrome and paving the way for microRNAs in non-alcoholic fatty liver disease.
Q39144663The biochemical alterations underlying post-burn hypermetabolism

Search more.