Apoptosis and insulin resistance in liver and peripheral tissues of morbidly obese patients is associated with different stages of non-alcoholic fatty liver disease.

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Apoptosis and insulin resistance in liver and peripheral tissues of morbidly obese patients is associated with different stages of non-alcoholic fatty liver disease. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00125-011-2130-8
P698PubMed publication ID21455726
P5875ResearchGate publication ID50940899

P50authorCecília RodriguesQ30421070
Rui E. CastroQ43087499
P2093author name stringA Costa
T Evangelista
J Coutinho
A Silvestre
D M S Ferreira
F Carepa
H Cortez-Pinto
M V Machado
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Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjectsQ34218011
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistanceQ34708975
Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic ConferenceQ35115696
Caspase-2 deficiency enhances aging-related traits in miceQ35688389
Apoptosis in alcoholic and nonalcoholic steatohepatitisQ36170407
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Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in miceQ36519843
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Phosphorylation of IRS proteins, insulin action, and insulin resistanceQ37252616
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Diabetes and apoptosis: lipotoxicityQ37473207
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The unpredictable caspase-2: what can it do?Q37671358
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From the metabolic syndrome to NAFLD or vice versa?Q37703968
Comparison of the effect of individual saturated and unsaturated fatty acids on cell growth and death induction in the human pancreatic beta-cell line NES2Y.Q40013622
A stress signaling pathway in adipose tissue regulates hepatic insulin resistanceQ41811449
Increased apoptosis in high-fat diet-induced nonalcoholic steatohepatitis in rats is associated with c-Jun NH2-terminal kinase activation and elevated proapoptotic BaxQ42155537
Octreotide induces caspase activation and apoptosis in human hepatoma HepG2 cells.Q42573914
Modulation of amyloid-β peptide-induced toxicity through inhibition of JNK nuclear localization and caspase-2 activation.Q42905339
Diagnosing insulin resistance by simple quantitative methods in subjects with normal glucose metabolismQ44666291
Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver diseaseQ44934521
Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathwayQ44967749
Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanismsQ45300618
Dose-response effect of elevated plasma free fatty acid on insulin signalingQ46513253
Molecular determinants of insulin resistance, cell apoptosis and lipid accumulation in non-alcoholic steatohepatitis.Q46863162
JNK1 but not JNK2 promotes the development of steatohepatitis in miceQ46865809
Cytokine regulation of skeletal muscle fatty acid metabolism: effect of interleukin-6 and tumor necrosis factor-alphaQ47586381
Targeted disruption of the tumor necrosis factor-alpha gene: metabolic consequences in obese and nonobese miceQ48630964
beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activationQ48932916
Trans-11 vaccenic acid dietary supplementation induces hypolipidemic effects in JCR:LA-cp rats.Q51438855
Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects.Q51466405
Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM.Q51580928
Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease.Q54691032
Apoptosis and Bcl-2 expression in the livers of patients with steatohepatitisQ57760188
Hepatocyte Apoptosis, Expression of Death Receptors, and Activation of NF-κB in the Liver of Nonalcoholic and Alcoholic Steatohepatitis PatientsQ57760193
Variation in the ADIPOQ gene promoter is associated with carotid intima media thickness independent of plasma adiponectin levels in healthy subjectsQ60462188
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitisQ73735584
Free fatty acids induce JNK-dependent hepatocyte lipoapoptosisQ82677113
P433issue7
P921main subjectpatientQ181600
insulin resistanceQ1053470
metabolic dysfunction–associated steatotic liver diseaseQ1546498
preproinsulinQ7240673
non-alcoholic fatty liverQ66299798
P304page(s)1788-1798
P577publication date2011-04-01
P1433published inDiabetologiaQ5270140
P1476titleApoptosis and insulin resistance in liver and peripheral tissues of morbidly obese patients is associated with different stages of non-alcoholic fatty liver disease.
P478volume54

Reverse relations

cites work (P2860)
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