| scholarly article | Q13442814 |
| P356 | DOI | 10.1371/JOURNAL.PPAT.1002594 |
| P953 | full work available online at | http://dx.plos.org/10.1371/journal.ppat.1002594 |
| https://europepmc.org/articles/PMC3305436 | ||
| https://europepmc.org/articles/PMC3305436?pdf=render | ||
| https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002594&type=printable | ||
| P932 | PMC publication ID | 3305436 |
| P698 | PubMed publication ID | 22438812 |
| P5875 | ResearchGate publication ID | 221967707 |
| P2093 | author name string | Haiming Wei | |
| Zhigang Tian | |||
| Cheng Sun | |||
| Yufeng Gao | |||
| Rui Sun | |||
| Binqing Fu | |||
| Xiaofeng Liao | |||
| P2860 | cites work | Loss of Smad3 in acute T-cell lymphoblastic leukemia. | Q53366155 |
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| Cutting Edge: Defective NK Cell Activation in X-Linked Lymphoproliferative Disease | Q56593901 | ||
| Hepatic expansion of a virus-specific regulatory CD8+ T cell population in chronic hepatitis C virus infection | Q57160316 | ||
| The apoptosis modulating role of SAP (SLAM associated protein) contributes to the symptomatology of the X linked lymphoproliferative disease | Q58023360 | ||
| The human liver contains multiple populations of NK cells, T cells, and CD3+CD56+ natural T cells with distinct cytotoxic activities and Th1, Th2, and Th0 cytokine secretion patterns | Q58143619 | ||
| Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation | Q59055770 | ||
| Outcome of anti-HBe positive chronic hepatitis B in alpha-interferon treated and untreated patients: a long term cohort study | Q61054098 | ||
| The natural history of chronic hepatitis B virus infection | Q64132783 | ||
| Expression of p21 in hepatocellular carcinoma and liver cirrhosis and its relation with HBV infection | Q68256321 | ||
| Measurements of Natural Killer (NK) Activity and NK-Cell Quantification | Q71544761 | ||
| Role of NKG2D in tumor cell lysis mediated by human NK cells: cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin | Q73740416 | ||
| Hepatitis B virus infection | Q73929492 | ||
| TGF-beta signaling, tumor suppression, and acute lymphoblastic leukemia | Q80418839 | ||
| Natural history and disease progression in Chinese chronic hepatitis B patients in immune-tolerant phase | Q80606419 | ||
| Clearance of hepatitis B e antigen in patients with chronic hepatitis B and genotypes A, B, C, D, and F | Q81404746 | ||
| Transforming growth factor-beta controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma | Q81685771 | ||
| Viral load reduction improves activation and function of natural killer cells in patients with chronic hepatitis B | Q82541525 | ||
| NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules | Q36370410 | ||
| 2B4 acts as a non-major histocompatibility complex binding inhibitory receptor on mouse natural killer cells | Q36399476 | ||
| NK cell activation through the NKG2D ligand MULT-1 is selectively prevented by the glycoprotein encoded by mouse cytomegalovirus gene m145. | Q36402602 | ||
| CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner | Q36403637 | ||
| Activation, coactivation, and costimulation of resting human natural killer cells | Q36652166 | ||
| Cytokine-driven regulation of NK cell functions in tumor immunity: role of the MICA-NKG2D system | Q36745910 | ||
| Management of hepatitis B: summary of a clinical research workshop | Q36773747 | ||
| Consequence of the SLAM-SAP signaling pathway in innate-like and conventional lymphocytes | Q37010543 | ||
| Wild-type and e antigen-minus hepatitis B viruses and course of chronic hepatitis. | Q37510933 | ||
| Natural killer cells in viral hepatitis: facts and controversies. | Q37769577 | ||
| Hepatitis B virus X protein overcomes all-trans retinoic acid-induced cellular senescence by downregulating levels of p16 and p21 via DNA methylation | Q39591270 | ||
| Hepatitis C virus-induced furin and thrombospondin-1 activate TGF-β1: role of TGF-β1 in HCV replication | Q39597392 | ||
| Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1. | Q39901596 | ||
| Molecular basis of the dual functions of 2B4 (CD244). | Q39975619 | ||
| IL-2/IL-18 prevent the down-modulation of NKG2D by TGF-beta in NK cells via the c-Jun N-terminal kinase (JNK) pathway | Q40214738 | ||
| CD4+CD25+ T regulatory cells suppress NK cell-mediated immunotherapy of cancer | Q40327394 | ||
| Hepatitis B virus immunopathogenesis | Q40444875 | ||
| RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo. | Q40474790 | ||
| Hepatitis B virus X antigen promotes transforming growth factor-beta1 (TGF-beta1) activity by up-regulation of TGF-beta1 and down-regulation of alpha2-macroglobulin | Q40591172 | ||
| Hepatic expansion of a virus-specific regulatory CD8(+) T cell population in chronic hepatitis C virus infection | Q40725950 | ||
| Changes of serum hepatitis B virus DNA and aminotransferase levels during the course of chronic hepatitis B virus infection in children | Q41837714 | ||
| TGF-beta downregulates the activating receptor NKG2D on NK cells and CD8+ T cells in glioma patients | Q42426054 | ||
| IL-21 down-regulates NKG2D/DAP10 expression on human NK and CD8+ T cells | Q42678415 | ||
| A study of TNF-alpha-238 and -308 polymorphisms with different outcomes of persistent hepatitis B virus infection in China | Q42809793 | ||
| Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta | Q42981721 | ||
| HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection | Q42986755 | ||
| Comment on "Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta". | Q42987369 | ||
| Natural killer cell functional dichotomy in chronic hepatitis B and chronic hepatitis C virus infections | Q43713361 | ||
| Genotypic resistance profile of hepatitis B virus (HBV) in a large cohort of nucleos(t)ide analogue-experienced Chinese patients with chronic HBV infection. | Q45368315 | ||
| The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function | Q45371390 | ||
| Cytokine gene polymorphisms in Japanese patients with hepatitis B virus infection--association between TGF-beta1 polymorphisms and hepatocellular carcinoma | Q45499638 | ||
| Acute exacerbations in Chinese patients with chronic hepatitis B virus (HBV) infection. Incidence, predisposing factors and etiology | Q45849476 | ||
| Inappropriate recruitment and activity by the Src homology region 2 domain-containing phosphatase 1 (SHP1) is responsible for receptor dominance in the SHIP-deficient NK cell | Q46868608 | ||
| Elevated TGF-beta1 secretion and down-modulation of NKG2D underlies impaired NK cytotoxicity in cancer patients | Q47371541 | ||
| Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA | Q22010440 | ||
| X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells | Q24676168 | ||
| Transforming growth factor beta 1 inhibits expression of NKp30 and NKG2D receptors: consequences for the NK-mediated killing of dendritic cells | Q24683311 | ||
| Aberrant Promoter Methylation Profiles of Tumor Suppressor Genes in Hepatocellular Carcinoma | Q27478395 | ||
| Defective NK cell activation in X-linked lymphoproliferative disease | Q28141366 | ||
| Smad-dependent and Smad-independent pathways in TGF-beta family signalling | Q28208250 | ||
| The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis | Q28355178 | ||
| Functions of natural killer cells | Q29614300 | ||
| NK cell recognition | Q29615107 | ||
| Chronic hepatitis B: update 2009 | Q29617409 | ||
| Up on the tightrope: natural killer cell activation and inhibition | Q29619175 | ||
| Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase | Q33745662 | ||
| Hepatitis C virus (HCV) evades NKG2D-dependent NK cell responses through NS5A-mediated imbalance of inflammatory cytokines. | Q33750016 | ||
| Blockade of immunosuppressive cytokines restores NK cell antiviral function in chronic hepatitis B virus infection | Q33781003 | ||
| Absence of mouse 2B4 promotes NK cell-mediated killing of activated CD8+ T cells, leading to prolonged viral persistence and altered pathogenesis | Q33882896 | ||
| Natural history of chronic HBV infection: special emphasis on the prognostic implications of the inactive carrier state versus chronic hepatitis | Q34157099 | ||
| Effects of human cytomegalovirus infection on ligands for the activating NKG2D receptor of NK cells: up-regulation of UL16-binding protein (ULBP)1 and ULBP2 is counteracted by the viral UL16 protein | Q34212265 | ||
| Management of hepatitis B: 2000--summary of a workshop | Q34263265 | ||
| Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures | Q34302587 | ||
| Hepatitis B e antigen-negative chronic hepatitis B. | Q34389603 | ||
| Host immune system gene targeting by a viral miRNA | Q34581221 | ||
| Strong influence of human leukocyte antigen (HLA)-DP gene variants on development of persistent chronic hepatitis B virus carriers in the Han Chinese population | Q34664029 | ||
| Hepatitis B virus X protein promotes proliferation and upregulates TGF-beta1 and CTGF in human hepatic stellate cell line, LX-2. | Q34942035 | ||
| Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes | Q36229197 | ||
| Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage | Q36267204 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | e1002594 | |
| P577 | publication date | 2012-03-15 | |
| P1433 | published in | PLOS Pathogens | Q283209 |
| P1476 | title | TGF-β1 down-regulation of NKG2D/DAP10 and 2B4/SAP expression on human NK cells contributes to HBV persistence | |
| TGF-β1 Down-Regulation of NKG2D/DAP10 and 2B4/SAP Expression on Human NK Cells Contributes to HBV Persistence | |||
| P478 | volume | 8 |
| Q37698781 | Activated hepatic stellate cells impair NK cell anti-fibrosis capacity through a TGF-β-dependent emperipolesis in HBV cirrhotic patients |
| Q38180339 | Advances in NKG2D ligand recognition and responses by NK cells |
| Q36101272 | Altered Immune Profiles of Natural Killer Cells in Chronic Hepatitis B Patients: A Systematic Review and Meta-Analysis |
| Q55208795 | Ambiguous roles of innate lymphoid cells in chronic development of liver diseases. |
| Q92920997 | Astragaloside III Enhances Anti-Tumor Response of NK Cells by Elevating NKG2D and IFN-γ |
| Q48834589 | Augmented anti-tumor activity of NK-92 cells expressing chimeric receptors of TGF-βR II and NKG2D. |
| Q36898390 | CD3(bright)CD56(+) T cells associate with pegylated interferon-alpha treatment nonresponse in chronic hepatitis B patients |
| Q87628568 | CD4(+) NKG2D(+) T cells induce NKG2D down-regulation in natural killer cells in CD86-RAE-1ε transgenic mice |
| Q35025435 | CD4(+)CD62L(+) central memory T cells can be converted to Foxp3(+) T cells |
| Q36742288 | Cimicifuga foetida L. plus adefovir effectively inhibits the replication of hepatitis B virus in patients with chronic hepatitis B. |
| Q35111019 | Constitutive but not inducible attenuation of transforming growth factor β signaling increases natural killer cell responses without directly affecting dendritic cells early after persistent viral infection |
| Q26771142 | Crosstalk between innate and adaptive immunity in hepatitis B virus infection |
| Q38283963 | Cytokine-Mediated Immunopathogenesis of Hepatitis B Virus Infections |
| Q35092599 | Decreased peripheral natural killer cells activity in the immune activated stage of chronic hepatitis B. |
| Q40086298 | Developmental and Functional Control of Natural Killer Cells by Cytokines |
| Q35758694 | Differential Expression of CX3CL1 in Hepatitis B Virus-Replicating Hepatoma Cells Can Affect the Migration Activity of CX3CR1+ Immune Cells |
| Q36457304 | Evolving role of 2B4/CD244 in T and NK cell responses during virus infection. |
| Q33652113 | Exosomes mediate hepatitis B virus (HBV) transmission and NK-cell dysfunction. |
| Q36597366 | Failure recovery of circulating NKG2D(+)CD56(dim)NK cells in HBV-associated hepatocellular carcinoma after hepatectomy predicts early recurrence |
| Q38283442 | Genomic expression profiling of NK cells in health and disease |
| Q38295864 | HBV and the immune response |
| Q49386850 | Hemacytotoxicity and natural killer lytic index: New parameters to evaluate natural killer cell immunity for clinical use in cancer |
| Q64078769 | Hepatic Natural Killer Cells: Organ-Specific Sentinels of Liver Immune Homeostasis and Physiopathology |
| Q37032202 | Hepatitis B Virus Replication in CD34+ Hematopoietic Stem Cells From Umbilical Cord Blood. |
| Q40333142 | High NKG2A expression contributes to NK cell exhaustion and predicts a poor prognosis of patients with liver cancer |
| Q36547384 | High serum levels of TGF-β in Iranians with chronic HBV infection |
| Q58580678 | Human CD96 correlates to NK cell exhaustion and predicts the prognosis of human hepatocellular carcinoma |
| Q35507485 | IFNγ producing CD8(+) T cells modified to resist major immune checkpoints induce regression of MHC class I-deficient melanomas |
| Q38541811 | Immune Response in Hepatitis B Virus Infection |
| Q64083350 | Immune response pattern varies with the natural history of chronic hepatitis B |
| Q38885002 | Immune responses and immunopathology in acute and chronic viral hepatitis |
| Q35075107 | Immune therapeutic strategies in chronic hepatitis B virus infection: virus or inflammation control? |
| Q41694097 | Immunobiology of hepatitis B virus infection. |
| Q36073739 | Immunological aspects of antiviral therapy of chronic hepatitis B virus and hepatitis C virus infections |
| Q28390399 | Immunological effects of the TGFβ-blocking antibody GC1008 in malignant pleural mesothelioma patients |
| Q91708036 | Impairment of NKG2D-Mediated Tumor Immunity by TGF-β |
| Q38134673 | Important roles played by TGF-β in hepatitis B infection. |
| Q100517652 | Innate lymphocytes: pathogenesis and therapeutic targets of liver diseases and cancer |
| Q42700237 | KIR3DS1/HLA-B Bw4-80Ile Genotype Is Correlated with the IFN-α Therapy Response in hepatitis B e antigen-Positive Chronic Hepatitis B. |
| Q26774237 | Liver natural killer cells: subsets and roles in liver immunity |
| Q35895721 | Long noncoding RNA derived from CD244 signaling epigenetically controls CD8+ T-cell immune responses in tuberculosis infection |
| Q38255751 | MICA SNPs and the NKG2D system in virus-induced HCC. |
| Q40077350 | Mechanisms of Hepatitis B Virus Persistence |
| Q90265781 | NK Cell Dysfunction and Checkpoint Immunotherapy |
| Q39431541 | NK Cell Exhaustion. |
| Q40673118 | NK Cells Help Induce Anti-Hepatitis B Virus CD8+ T Cell Immunity in Mice |
| Q27001052 | NK cell receptor imbalance and NK cell dysfunction in HBV infection and hepatocellular carcinoma |
| Q38180372 | NK cells in hepatitis B virus infection: a potent target for immunotherapy. |
| Q26851977 | NK cells in immunotolerant organs |
| Q43237496 | NK cells: a double-edged sword in chronic hepatitis B virus infection. |
| Q39017180 | NKG2D ligation relieves 2B4-mediated NK-cell self-tolerance in mice |
| Q33682274 | NKG2D+CD4+ T Cells Kill Regulatory T Cells in a NKG2D-NKG2D Ligand- Dependent Manner in Systemic Lupus Erythematosus |
| Q59795771 | Natural Killer Cell Dysfunction in Hepatocellular Carcinoma: Pathogenesis and Clinical Implications |
| Q26767448 | Natural Killer Cells and Liver Fibrosis |
| Q38527482 | Natural killer cell dysfunction in hepatocellular carcinoma and NK cell-based immunotherapy |
| Q42274457 | Natural killer cell functional dichotomy: a feature of chronic viral hepatitis? |
| Q27025451 | Natural killer cells in liver disease |
| Q52314600 | Natural killer cells in liver diseases |
| Q33734554 | Peg-Interferon Lambda Treatment Induces Robust Innate and Adaptive Immunity in Chronic Hepatitis B Patients |
| Q40106389 | Ratios of T-helper 2 Cells to T-helper 1 Cells and Cytokine Levels in Patients with Hepatitis B. |
| Q40098295 | Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis |
| Q35877272 | Regulation of T cell function by microRNA-720. |
| Q39097028 | Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and Infection |
| Q38121579 | Reversal of hepatitis B virus‐induced systemic immune tolerance by intrinsic innate immune stimulation |
| Q39995705 | Role natural killer group 2D-ligand interactions in hepatitis B infection. |
| Q26768530 | Role of Tim-3 in hepatitis B virus infection: An overview |
| Q26996034 | Subsets of human natural killer cells and their regulatory effects |
| Q55078631 | Targeting the Epidermal Growth Factor Receptor Can Counteract the Inhibition of Natural Killer Cell Function Exerted by Colorectal Tumor-Associated Fibroblasts. |
| Q47373461 | The Broad Spectrum of Human Natural Killer Cell Diversity |
| Q55072526 | The Donor Major Histocompatibility Complex Class I Chain-Related Molecule A Allele rs2596538 G Predicts Cytomegalovirus Viremia in Kidney Transplant Recipients. |
| Q90723756 | The Good and the Bad of Natural Killer Cells in Virus Control: Perspective for Anti-HBV Therapy |
| Q58785685 | The Paradoxical Role of NKG2D in Cancer Immunity |
| Q90706071 | The Potential for Cancer Immunotherapy in Targeting Surgery-Induced Natural Killer Cell Dysfunction |
| Q39107305 | The effect of Echinococcus granulosus on spleen cells and TGF-β expression in the peripheral blood of BALB/c mice. |
| Q64982427 | The functional role of exosome in hepatocellular carcinoma. |
| Q43435087 | Therapeutic recovery of hepatitis B virus (HBV)-induced hepatocyte-intrinsic immune defect reverses systemic adaptive immune tolerance |
| Q41216339 | Umbilical cord blood plasma contains soluble NKG2D ligands that mediate loss of natural killer cell function and cytotoxicity |
| Q26748421 | Viral Evasion of Natural Killer Cell Activation |
| Q57300237 | Viral and Nonviral Engineering of Natural Killer Cells as Emerging Adoptive Cancer Immunotherapies |
| Q39140544 | hIFN-α gene modification augments human natural killer cell line anti-human hepatocellular carcinoma function |
| Q33730462 | hrHPV E5 oncoprotein: immune evasion and related immunotherapies. |
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