Ménage à Trois: The Role of Neurotransmitters in the Energy Metabolism of Astrocytes, Glutamatergic, and GABAergic Neurons

scientific article published on April 4, 2012

Ménage à Trois: The Role of Neurotransmitters in the Energy Metabolism of Astrocytes, Glutamatergic, and GABAergic Neurons is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/JCBFM.2012.31
P953full work available at URLhttps://doi.org/10.1038/jcbfm.2012.31
https://europepmc.org/articles/PMC3421085
https://europepmc.org/articles/PMC3421085?pdf=render
https://journals.sagepub.com/doi/full-xml/10.1038/jcbfm.2012.31
https://journals.sagepub.com/doi/pdf/10.1038/jcbfm.2012.31
P932PMC publication ID3421085
P698PubMed publication ID22472605
P5875ResearchGate publication ID223985141

P50authorDaniela CalvettiQ63865093
Erkki SomersaloQ63865092
P2860cites workSupply and demand in cerebral energy metabolism: the role of nutrient transportersQ24671074
The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer.Q27863346
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An energy budget for signaling in the grey matter of the brainQ29616192
Astrocytes, from brain glue to communication elements: the revolution continuesQ29619493
Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilizationQ29620724
Changes in glucose uptake rather than lactate shuttle take center stage in subserving neuroenergetics: evidence from mathematical modeling.Q30476702
Carboxylation and anaplerosis in neurons and gliaQ30654572
Energy metabolism in astrocytes: high rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysisQ31048542
Response to 'comment on recent modeling studies of astrocyte-neuron metabolic interactions': much ado about nothing.Q33852904
The contribution of GABA to glutamate/glutamine cycling and energy metabolism in the rat cortex in vivoQ33936559
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Oxidative and nonoxidative metabolism of excited neurons and astrocytesQ34504180
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Energy Substrates for Neurons during Neural Activity: A Critical Review of the Astrocyte-Neuron Lactate Shuttle HypothesisQ35576702
Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activityQ35677747
Neuronal-glial glucose oxidation and glutamatergic-GABAergic function.Q36366441
Determination of the rate of the glutamate/glutamine cycle in the human brain by in vivo 13C NMR.Q36418950
The glutamate-glutamine cycle is not stoichiometric: fates of glutamate in brainQ36936969
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Bioenergetics of cerebral ischemia: a cellular perspectiveQ37221302
Bayesian flux balance analysis applied to a skeletal muscle metabolic model.Q39776363
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Energetics of Inhibition: Insights with a Computational Model of the Human GABAergic Neuron–Astrocyte Cellular ComplexQ41777447
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Neuroglial metabolism in the awake rat brain: CO2 fixation increases with brain activity.Q45188907
An integrative dynamic model of brain energy metabolism using in vivo neurochemical measurements.Q46035676
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Interaction between astrocytes and neurons studied using a mathematical model of compartmentalized energy metabolismQ46523634
Purification of cytosolic malic enzyme from bovine brain, generation of monoclonal antibodies, and immunocytochemical localization of the enzyme in glial cells of neural primary culturesQ48312323
Quantification of cortical GABA-glutamine cycling rate using in vivo magnetic resonance signal of [2-13C]GABA derived from glia-specific substrate [2-13C]acetateQ48390467
Complex glutamate labeling from [U-13C]glucose or [U-13C]lactate in co-cultures of cerebellar neurons and astrocytesQ48403996
Metabolism of lactate in cultured GABAergic neurons studied by 13C nuclear magnetic resonance spectroscopyQ48564331
Pyruvate carboxylase activity in primary cultures of astrocytes and neuronsQ48719469
Dynamic activation model for a glutamatergic neurovascular unit.Q51622298
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectneurotransmitterQ162657
astrocyteQ502961
neurological modelsQ73501278
energy metabolismQ30225378
P304page(s)1472-1483
P577publication date2012-04-04
P1433published inJournal of Cerebral Blood Flow & MetabolismQ14663525
P1476titleMénage à trois: the role of neurotransmitters in the energy metabolism of astrocytes, glutamatergic, and GABAergic neurons
Ménage à Trois: The Role of Neurotransmitters in the Energy Metabolism of Astrocytes, Glutamatergic, and GABAergic Neurons
P478volume32

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cites work (P2860)
Q38788230Astroglial glutamate transporters coordinate excitatory signaling and brain energetics.
Q38821280Computational Flux Balance Analysis Predicts that Stimulation of Energy Metabolism in Astrocytes and their Metabolic Interactions with Neurons Depend on Uptake of K+ Rather than Glutamate.
Q92043375Computational singular perturbation analysis of brain lactate metabolism
Q35013625Energy metabolism and glutamate-glutamine cycle in the brain: a stoichiometric modeling perspective
Q37637468Genome-Scale Reconstruction of the Human Astrocyte Metabolic Network
Q45355296Glutamatergic and GABAergic energy metabolism measured in the rat brain by 13C NMR spectroscopy at 14.1 T
Q51052738Polyglucosan neurotoxicity caused by glycogen branching enzyme deficiency can be reversed by inhibition of glycogen synthase
Q41820259Quantitative in silico Analysis of Neurotransmitter Pathways Under Steady State Conditions
Q38045780The metabolism of neurons and astrocytes through mathematical models.
Q48768537Uncertainty quantification in flux balance analysis of spatially lumped and distributed models of neuron-astrocyte metabolism.

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