SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

scientific article

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/0014-5793(94)00773-X
P698PubMed publication ID8070571

P2093author name stringD Caput
D Shire
B Calandra
M Rinaldi-Carmona
S Martinez
C Congy
F Barth
J Maruani
G Néliat
M Héaulme
P433issue2-3
P407language of work or nameEnglishQ1860
P921main subjectCNR2Q17907844
cannabinoid receptorQ421237
cannabinoidsQ422936
P304page(s)240-244
P577publication date1994-08-01
P1433published inFEBS LettersQ1388051
P1476titleSR141716A, a potent and selective antagonist of the brain cannabinoid receptor
P478volume350

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cites work (P2860)
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Q46784380Effect of the cannabinoid CB1 receptor antagonist SR-141716A on ethanol self-administration and ethanol-seeking behaviour in rats
Q36357902Effect of the cannabinoid CB1 receptor antagonist rimonabant on nociceptive responses and adjuvant-induced arthritis in obese and lean rats
Q35028454Effect of the cannabinoid receptor agonist WIN55212-2 on sympathetic cardiovascular regulation
Q43965495Effect of the cannabinoid receptor ligand, WIN 55,212-2, on superoxide anion and TNF-alpha production by human mononuclear cells
Q42478605Effects of CB(1) cannabinoid receptor activation on cerebellar granule cell nitric oxide synthase activity
Q43754879Effects of CB1 cannabinoid receptor blockade on ethanol preference after chronic ethanol administration
Q45114552Effects of SR 141716A after acute or chronic cannabinoid administration in dogs
Q80423729Effects of SR141716 and WIN 55,212-2 on tolerance to ethanol in rats using the acute and rapid procedures
Q44865464Effects of SR141716A on diazepam substitution for delta9-tetrahydrocannabinol in rat drug discrimination
Q27312372Effects of acute and repeated dosing of the synthetic cannabinoid CP55,940 on intracranial self-stimulation in mice
Q44077059Effects of anandamide on embryo implantation in the mouse
Q30442731Effects of cannabinoid drugs on the deficit of prepulse inhibition of startle in an animal model of schizophrenia: the SHR strain
Q46712800Effects of cannabinoid receptor activation on rabbit bisected vas deferens strips
Q43158845Effects of cannabinoid receptor ligands on electrophysiological properties of myenteric neurones of the guinea-pig ileum
Q28363784Effects of cannabinoids on adrenaline release from adrenal medullary cells
Q42538098Effects of cannabinoids on prolactin and gonadotrophin secretion: involvement of changes in hypothalamic gamma-aminobutyric acid (GABA) inputs
Q42491040Effects of castration on cannabinoid cb receptor expression and on the biological actions of cannabinoid in the parotid gland
Q43445796Effects of chronic oral rimonabant administration on energy budgets of diet-induced obese C57BL/6 mice
Q48428879Effects of endocannabinoid neurotransmission modulators on brain stimulation reward
Q37692352Effects of opioids, cannabinoids, and vanilloids on body temperature
Q36223797Effects of palmitoylethanolamide on aqueous humor outflow
Q42528193Effects of perinatal exposure to delta 9-tetrahydrocannabinol on the fetal and early postnatal development of tyrosine hydroxylase-containing neurons in rat brain
Q44209138Effects of pharmacological manipulations of cannabinoid receptors on severity of dystonia in a genetic model of paroxysmal dyskinesia
Q46769723Effects of rimonabant, a cannabinoid CB1 receptor ligand, on energy expenditure in lean rats
Q46316802Effects of sibutramine and rimonabant in rats trained to discriminate between 22- and 2-h food deprivation
Q44867449Effects of the cannabinoid CB(1) receptor antagonist, SR141716A, after Delta(9)-tetrahydrocannabinol withdrawal
Q38333962Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lep(ob)/Lep(ob) mice
Q52202168Effects of the cannabinoid CB1 receptor antagonist SR141716A on the behavior of pigeons and rats.
Q42076773Effects of the cannabinoid CB1 receptor antagonist rimonabant on distinct measures of impulsive behavior in rats.
Q33865224Effects of the endogeneous cannabinoid, anandamide, on neuronal activity in rat hippocampal slices
Q43672168Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits.
Q34244610Efficacy of a dose range of surinabant, a cannabinoid receptor blocker, for smoking cessation: a randomized controlled clinical trial
Q31059589Efficacy of rimonabant and other cannabinoid CB1 receptor antagonists in reducing food intake and body weight: preclinical and clinical data.
Q45051487Efficient and highly regioselective synthesis of ethyl 1-(2,4-dichlorophenyl)-1H-pyrazole-3-carboxylates under ultrasound irradiation
Q35771406Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge
Q33997873Endocannabinoid binding to the cannabinoid receptors: what is known and what remains unknown
Q36108722Endocannabinoid control of food intake and energy balance
Q36711160Endocannabinoid mechanisms of pain modulation
Q35594842Endocannabinoid signaling directs periimplantation events
Q46075930Endocannabinoid signaling regulates spontaneous transmitter release from embryonic retinal amacrine cells
Q50780213Endocannabinoid system in frog and rodent testis: type-1 cannabinoid receptor and fatty acid amide hydrolase activity in male germ cells.
Q36357182Endocannabinoid system involvement in brain reward processes related to drug abuse
Q37119281Endocannabinoid system overactivity and the metabolic syndrome: prospects for treatment
Q37363621Endocannabinoid-mediated control of synaptic transmission
Q55282369Endocannabinoids
Q43658822Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis
Q34495800Endocannabinoids and Metabolic Disorders.
Q36257249Endocannabinoids and liver disease--review
Q38593136Endocannabinoids and the Digestive Tract and Bladder in Health and Disease
Q36981004Endocannabinoids and the control of energy homeostasis
Q37412217Endocannabinoids and the heart.
Q36214144Endocannabinoids and their implications for epilepsy
Q34099006Endocannabinoids as cardiovascular modulators
Q41742759Endocannabinoids: a new class of vasoactive substances
Q61479731Endogenous cannabinoid system as a modulator of food intake
Q52196139Endogenous cannabinoids as an aversive or counter-rewarding system in the rat.
Q43818881Endogenous cannabinoids mediate hypotension after experimental myocardial infarction
Q44279121Endogenous cannabinoids: a new target in the treatment of obesity
Q56880417Endothelium-dependent Relaxation in Response to Ethanol in the Porcine Isolated Pulmonary Artery
Q46673452Enhancement of endocannabinoid neurotransmission through CB1 cannabinoid receptors counteracts the reinforcing and psychostimulant effects of cocaine
Q34610463Evaluation of (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)-quinuclidin-3-one analogues as novel, high affinity ligands for CB1 and CB2 cannabinoid receptors
Q34858094Evaluation of [11C]PipISB and [18F]PipISB in monkey as candidate radioligands for imaging brain cannabinoid type-1 receptors in vivo
Q52141091Evaluation of the analgesic effect of 4-anilidopiperidine scaffold containing ureas and carbamates.
Q40935147Evaluation of the cannabinoid CB2 receptor-selective antagonist, SR144528: further evidence for cannabinoid CB2 receptor absence in the rat central nervous system
Q43872448Evaluation of the reinforcing effects of the cannabinoid CB1 receptor antagonist, SR141716, in rhesus monkeys
Q43064653Evaluation of the role of striatal cannabinoid CB1 receptors on movement activity of parkinsonian rats induced by reserpine
Q48337260Evidence for a role of endogenous cannabinoids in the modulation of acute and tonic pain sensitivity
Q42434209Evidence for both inverse agonism at the cannabinoid CB1 receptor and the lack of an endogenous cannabinoid tone in the rat and guinea-pig isolated ileum myenteric plexus-longitudinal muscle preparation
Q42014580Evidence for inverse agonism of SR141716A at human recombinant cannabinoid CB1 and CB2 receptors
Q43812206Evidence for presynaptic cannabinoid CB(1) receptor-mediated inhibition of noradrenaline release in the guinea pig lung
Q33720099Evidence for the presence of CB1 cannabinoid receptors on peripheral neurones and for the existence of neuronal non-CB1 cannabinoid receptors
Q34454662Evidence for the presence of CB2-like cannabinoid receptors on peripheral nerve terminals.
Q35874137Evidence for the presence of cannabinoid CB1 receptors in mouse urinary bladder
Q42003359Evidence of a novel site mediating anandamide-induced negative inotropic and coronary vasodilatator responses in rat isolated hearts.
Q28378272Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells
Q35026518Evidence that methyl arachidonyl fluorophosphonate is an irreversible cannabinoid receptor antagonist
Q48726145Examination of the effect of the cannabinoid receptor agonist, CP 55,940, on electrically evoked transmitter release from rat brain slices
Q41904764Excitatory transmission to the circular muscle of the guinea-pig ileum: evidence for the involvement of cannabinoid CB1 receptors
Q35837682Exogenous and endogenous cannabinoids suppress inhibitory neurotransmission in the human neocortex
Q58743634Exploring the Ligand Efficacy of Cannabinoid Receptor 1 (CB1) using Molecular Dynamics Simulations
Q44342705Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors
Q24309438Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations
Q90321305Extractions of Medical Cannabis Cultivars and the Role of Decarboxylation in Optimal Receptor Responses
Q48136699Extrapyramidal and neuroendocrine effects of AM404, an inhibitor of the carrier-mediated transport of anandamide
Q42487420Facilitation and inhibition by capsaicin of cholinergic neurotransmission in the guinea-pig small intestine
Q36300457Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture
Q39771468Flow Synthesis and Biological Studies of an Analgesic Adamantane Derivative That Inhibits P2X7-Evoked Glutamate Release
Q34004234Fluorinated cannabinoid CB2 receptor ligands: synthesis and in vitro binding characteristics of 2-oxoquinoline derivatives
Q47281894Food energy efficiency, cannabinoids, and a slow death of the weight loss dogma
Q33768340Food for thought: endocannabinoid modulation of lipogenesis
Q34786818From cannabis to cannabinergics: new therapeutic opportunities
Q37370306From drugs to deprivation: a Bayesian framework for understanding models of psychosis
Q35586753From membrane phospholipid defects to altered neurotransmission: is arachidonic acid a nexus in the pathophysiology of schizophrenia?
Q44011406Functional assessment of neuronal cannabinoid receptors in the muscular layers of human ileum and colon
Q60155181Functional expression of cell surface cannabinoid CB1 receptors on presynaptic inhibitory terminals in cultured rat hippocampal neurons
Q35950894Functional genomics strategies to identify susceptibility genes and treatment targets in alcohol dependence
Q43662870Functional interaction between opioid and cannabinoid receptors in drug self-administration.
Q34750566Functions of cannabinoid receptors in the hippocampus
Q36341641Further advances in the synthesis of endocannabinoid-related ligands
Q35874121Further evidence for the presence of cannabinoid CB1 receptors in guinea-pig small intestine
Q37110510GLP-1R agonism enhances adjustable gastric banding in diet-induced obese rats
Q28469322Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice
Q46947462Genetic impairment of frontocortical endocannabinoid degradation and high alcohol preference
Q43503383Genomic and functional changes induced by the activation of the peripheral cannabinoid receptor CB2 in the promyelocytic cells HL-60. Possible involvement of the CB2 receptor in cell differentiation
Q51980585Grooming, scratching and feeding: role of response competition in acute anorectic response to rimonabant in male rats.
Q26783258Growth Hormone Secretagogue Receptor Dimers: A New Pharmacological Target(1,2,3)
Q43263219Haloperidol, but not clozapine, produces dramatic catalepsy in delta9-THC-treated rats: possible clinical implications.
Q24595389Head-twitch response in rodents induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine: a comprehensive history, a re-evaluation of mechanisms, and its utility as a model
Q43670435Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors
Q35347646High-fat diet-induced insulin resistance does not increase plasma anandamide levels or potentiate anandamide insulinotropic effect in isolated canine islets
Q41013027High-level expression of the human CB2 cannabinoid receptor using a baculovirus system.
Q33765623High-throughput screening for modulators of protein-protein interactions: use of photonic crystal biosensors and complementary technologies
Q33655408Hippocampal CB(1) receptors mediate the memory impairing effects of Delta(9)-tetrahydrocannabinol
Q34748762Hippocampal neurotoxicity of Delta9-tetrahydrocannabinol.
Q36434447How many sites of action for endocannabinoids to control energy metabolism?
Q34320139Hu 210: a potent tool for investigations of the cannabinoid system.
Q28190374Hypersensitization of the Orexin 1 receptor by the CB1 receptor: evidence for cross-talk blocked by the specific CB1 antagonist, SR141716
Q38340750Hypoactivity of the spinal cannabinoid system results in NMDA-dependent hyperalgesia.
Q40799260Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues.
Q36452521Hypothalamic regulatory pathways and potential obesity treatment targets
Q43448744Hypothalamus-pituitary axis: an obligatory target for endocannabinoids to inhibit steroidogenesis in frog testis
Q37183687Hypothesis-driven medication discovery for the treatment of psychostimulant addiction
Q77794122Imidazoline binding sites and receptors in cardiovascular tissue
Q37244823Immunoactive effects of cannabinoids: considerations for the therapeutic use of cannabinoid receptor agonists and antagonists
Q47242856Immunolocalization of CB1 receptor in rat striatal neurons: a confocal microscopy study.
Q35943778Improgan-induced hypothermia: a role for cannabinoid receptors in improgan-induced changes in nociceptive threshold and body temperature
Q48973251Improvement of memory in rodents by the selective CB1 cannabinoid receptor antagonist, SR 141716.
Q38612135In silico mapping of allosteric ligand binding sites in type-1 cannabinoid receptor.
Q24643672In vitro and in vivo characterization of A-796260: a selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models
Q34039683In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate binding
Q35028193In vitro functional evidence of neuronal cannabinoid CB1 receptors in human ileum
Q74340550In vivo and in vitro treatment with the synthetic cannabinoid CP55, 940 decreases the in vitro migration of macrophages in the rat: involvement of both CB1 and CB2 receptors
Q73223400In vivo characterization of the specific cannabinoid receptor antagonist, SR141716A: behavioral and cellular responses after acute and chronic treatments
Q77766471Increased motivation for beer in rats following administration of a cannabinoid CB1 receptor agonist
Q35042648Influence of cannabinoids on the delayed rectifier in freshly dissociated smooth muscle cells of the rat aorta
Q46107799Influence of intracerebroventricular or intraperitoneal administration of cannabinoid receptor agonist (WIN 55,212-2) and inverse agonist (AM 251) on the regulation of food intake and hypothalamic serotonin levels
Q28143431Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding
Q59068519Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes
Q28283718Inhibition of FAAH and activation of PPAR: new approaches to the treatment of cognitive dysfunction and drug addiction
Q48262695Inhibition of cerebral type 1 cannabinoid receptors is associated with impaired auditory mismatch negativity generation in the ketamine model of schizophrenia
Q35874165Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves
Q35045697Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guinea-pigs by cannabinoid (CB2) receptor activation
Q48704955Inhibition of hippocampal acetylcholine release by cannabinoids: reversal by SR 141716A.
Q39124297Inhibition of interleukin-8 release in the human colonic epithelial cell line HT-29 by cannabinoids
Q71378280Inhibition of long-term potentiation in rat hippocampal slices by anandamide and WIN55212-2: reversal by SR141716 A, a selective antagonist of CB1 cannabinoid receptors
Q44349438Inhibition of opioid-degrading enzymes potentiates delta9-tetrahydrocannabinol-induced antinociception in mice
Q55042395Inhibition of salivary secretion by activation of cannabinoid receptors.
Q44746104Inhibition of voltage-sensitive sodium channels by the cannabinoid 1 receptor antagonist AM 251 in mammalian brain
Q36964922Inhibitory activity of the novel CB2 receptor agonist, GW833972A, on guinea-pig and human sensory nerve function in the airways
Q32144479Inhibitory effects of SR141716A on G-protein activation in rat brain
Q39987047Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression
Q48571061Interaction of brain cannabinoid receptors with guanine nucleotide binding protein: a radioligand binding study
Q37444813Interaction of the cannabinoid and opioid systems in the modulation of nociception
Q35809384Interactions between endocannabinoids and stress-induced decreased sensitivity to natural reward
Q43355908Interactions between the CB1 receptor agonist Delta 9-THC and the CB1 receptor antagonist SR-141716 in rats: open-field revisited.
Q33758351Interactions of Cannabinoids With Biochemical Substrates
Q85948164Interference with acute nausea and anticipatory nausea in rats by fatty acid amide hydrolase (FAAH) inhibition through a PPARα and CB1 receptor mechanism, respectively: a double dissociation
Q35310056Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide
Q43194095Intrinsic effects of AM4113, a putative neutral CB1 receptor selective antagonist, on open-field behaviors in rats
Q37778511Inverse Agonism at Serotonin and Cannabinoid Receptors
Q73011648Inverse agonist properties of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2, 4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide HCl (SR141716A) and 1-(2-chlorophenyl)-4-cyano-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxyl ic acid phenylamide (CP-272871)
Q45983403Investigation of endocannabinoid modulation of conditioned responding evoked by a nicotine CS and the Pavlovian stimulus effects of CP 55,940 in adult male rats.
Q36452404Investigations on the 4-quinolone-3-carboxylic acid motif part 5: modulation of the physicochemical profile of a set of potent and selective cannabinoid-2 receptor ligands through a bioisosteric approach.
Q73879622Involvement of a cannabinoid in endothelium-derived hyperpolarizing factor-mediated coronary vasorelaxation
Q37361093Involvement of a non-CB1/CB2 cannabinoid receptor in the aqueous humor outflow-enhancing effects of abnormal-cannabidiol
Q28349586Involvement of cannabinoids in the cardioprotection induced by lipopolysaccharide
Q42471169Involvement of the carboxyl terminus of the third intracellular loop of the cannabinoid CB1 receptor in constitutive activation of Gs.
Q47963301Ipsilateral turning behavior induced by unilateral microinjections of a cannabinoid into the rat subthalamic nucleus
Q36847055Isolation and expression of a mouse CB1 cannabinoid receptor gene. Comparison of binding properties with those of native CB1 receptors in mouse brain and N18TG2 neuroblastoma cells.
Q34098379JWH-018 in rhesus monkeys: differential antagonism of discriminative stimulus, rate-decreasing, and hypothermic effects.
Q35045710Lack of CB1 receptors increases noradrenaline release in vas deferens without affecting atrial noradrenaline release or cortical acetylcholine release
Q42492989Lack of response suppression follows repeated ventral tegmental cannabinoid administration: an in vitro electrophysiological study
Q36408464Latest advances in novel cannabinoid CB(2) ligands for drug abuse and their therapeutic potential
Q28211969Leptin-regulated endocannabinoids are involved in maintaining food intake
Q37164807Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond
Q38031743Limitations in anti-obesity drug development: the critical role of hunger-promoting neurons.
Q90026690Lipokines and Thermogenesis
Q58126117Liquid Chromatographic Method with Ultraviolet Absorbance Detection for Measurement of Rimonabant in Human Plasma
Q33821608Local administration of delta9-tetrahydrocannabinol attenuates capsaicin-induced thermal nociception in rhesus monkeys: a peripheral cannabinoid action
Q21142667Localization and function of the cannabinoid CB1 receptor in the anterolateral bed nucleus of the stria terminalis
Q31813503Localization and mechanisms of action of cannabinoid receptors at the glutamatergic synapses of the mouse nucleus accumbens.
Q73109965Locomotor activity and occupancy of brain cannabinoid CB1 receptors by the antagonist/inverse agonist AM281
Q47726731Long-lasting in vivo effects of the cannabinoid CB1 antagonist AM6538.
Q40552011Long-term plasticity of endocannabinoid signaling induced by developmental febrile seizures.
Q33373681Loss of cannabinoid receptor CB1 induces preterm birth
Q24671514Marijuana and cannabinoid regulation of brain reward circuits
Q36712200Marijuana dependence: not just smoke and mirrors
Q34986723Marijuana withdrawal syndrome in the animal model
Q74608042Marijuana, immunity and infection
Q40878576Marijuana. Respiratory tract effects
Q39635726Measurement of Inverse Agonism of the Cannabinoid Receptors
Q41683694Mechanism of cannabinoid effects on long-term potentiation and depression in hippocampal CA1 neurons.
Q33895436Mechanisms of cannabinoid inhibition of GABA(A) synaptic transmission in the hippocampus.
Q40622959Membrane cholesterol but not putative receptors mediates anandamide-induced hepatocyte apoptosis
Q92994067Membrane-associated periodic skeleton is a signaling platform for RTK transactivation in neurons
Q34321804Memory reconsolidation and extinction have distinct temporal and biochemical signatures.
Q34750833Mesolimbic dopaminergic decline after cannabinoid withdrawal
Q73292745Metabolic stimulation of mouse spleen lymphocytes by low doses of delta9-tetrahydrocannabinol
Q37211788Metabotropic glutamate and cannabinoid receptor crosstalk in periaqueductal grey pain processing
Q44274441Microinjection of a cannabinoid receptor antagonist into the NTS increases baroreflex duration in dogs
Q44303656Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptor
Q43264356Modulation of (3)H-noradrenaline release by presynaptic opioid, cannabinoid and bradykinin receptors and beta-adrenoceptors in mouse tissues
Q43774276Modulation of cytokine responses in Corynebacterium parvum-primed endotoxemic mice by centrally administered cannabinoid ligands
Q44532208Modulation of electrically evoked acetylcholine release through cannabinoid CB1 receptors: evidence for an endocannabinoid tone in the human neocortex.
Q37199151Modulation of excitatory synaptic transmission by Delta 9-tetrahydrocannabinol switches from agonist to antagonist depending on firing rate
Q33764237Modulation of fear memory by dietary polyunsaturated fatty acids via cannabinoid receptors.
Q44100817Modulation of gastric emptying and gastrointestinal transit in rats through intestinal cannabinoid CB(1) receptors
Q41371378Modulation of neurotransmission by cannabinoids in the basal ganglia
Q36259799Modulation of the endocannabinoid system: therapeutic potential against cocaine dependence
Q39124226Modulation of the release of endogenous adenosine by cannabinoids in the myenteric plexus-longitudinal muscle preparation of the guinea-pig ileum
Q39102188Molecular Pharmacology of Phytocannabinoids
Q24336332Molecular cloning, expression and function of the murine CB2 peripheral cannabinoid receptor
Q41837782Molecular mechanisms for the destabilization and restabilization of reactivated spatial memory in the Morris water maze
Q41191025Molecular neurobiology of the cannabinoid receptor.
Q34098959Molecular probes for the cannabinoid receptors
Q39141240Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling
Q33720160Motor actions of cannabinoids in the basal ganglia output nuclei
Q34373631Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids.
Q31417471Mutational analysis and molecular modelling of the antagonist SR 144528 binding site on the human cannabinoid CB(2) receptor
Q34904406N-(4-cyanotetrahydro-2H-pyran-4-yl) and N-(1-cyanocyclohexyl) derivatives of 1,5-diarylpyrazole-3-carboxamides showing high affinity for 18 kDa translocator protein and/or cannabinoid receptors
Q42670939Neurobehavioral effects of anandamide and cannabinoid receptor gene expression in mice
Q45711992Neuroleptic-like profile of the cannabinoid agonist, HU 210, on rodent behavioural models
Q48341589Neuronal responses to cannabinoid receptor ligands in the solitary tract nucleus
Q38395251New approaches in the design and development of cannabinoid receptor ligands: multifunctional and bivalent compounds
Q34494301New insights on the role of the endocannabinoid system in the regulation of energy balance.
Q44468306New isochaetochromin, an inhibitor of triacylglycerol synthesis in mammalian cells, produced by Penicillium sp. FKI-4942: I. Taxonomy, fermentation, isolation and biological properties
Q37660087New therapeutic potential for psychoactive natural products
Q45006435Nicotine-associated cues maintain nicotine-seeking behavior in rats several weeks after nicotine withdrawal: reversal by the cannabinoid (CB1) receptor antagonist, rimonabant (SR141716).
Q38185075No more pain upon Gq-protein-coupled receptor activation: role of endocannabinoids
Q34179008Nonpsychotropic cannabinoid receptors regulate microglial cell migration.
Q36783972Novel 3-substituted rimonabant analogues lack Δ(9) -tetrahydrocannabinol-like abuse-related behavioural effects in mice
Q45081681Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide
Q34431882Novel physiologic functions of endocannabinoids as revealed through the use of mutant mice
Q48179872Novel pyrrolocycloalkylpyrazole analogues as CB1 ligands.
Q37729807Novel selective cannabinoid CB(1) receptor antagonist MJ08 with potent in vivo bioactivity and inverse agonistic effects.
Q40083173Novel, potent THC/anandamide (hybrid) analogs.
Q33899423O-1057, a potent water-soluble cannabinoid receptor agonist with antinociceptive properties
Q47808605Occlusion of the presynaptic action of cannabinoids in rat substantia nigra pars reticulata by cadmium.
Q44352771Opioid and cannabinoid receptor-mediated regulation of the increase in adrenocorticotropin hormone and corticosterone plasma concentrations induced by central administration of delta(9)-tetrahydrocannabinol in rats
Q40165311Opposing actions of endocannabinoids on cholangiocarcinoma growth: recruitment of Fas and Fas ligand to lipid rafts
Q41229463Oral Administration of the Endocannabinoid Anandamide during Lactation: Effects on Hypothalamic Cannabinoid Type 1 Receptor and Food Intake in Adult Mice.
Q44456158Overeating, alcohol and sucrose consumption decrease in CB1 receptor deleted mice
Q33421146Pain modulation by release of the endogenous cannabinoid anandamide
Q40639597Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility.
Q28393331Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation
Q42921222Peripheral Endocannabinoid System‐Mediated Actions of Rimonabant on Growth Hormone Secretion are Ghrelin‐Dependent
Q37669645Peripheral metabolic effects of endocannabinoids and cannabinoid receptor blockade
Q38754299Peripherally Selective Cannabinoid 1 Receptor (CB1R) Agonists for the Treatment of Neuropathic Pain
Q38490183Peripherally acting CB1-receptor antagonist: the relative importance of central and peripheral CB1 receptors in adiposity control
Q28360193Pharmacological analysis of cannabinoid receptor activity in the rat vas deferens
Q33893580Pharmacological characterisation of cannabinoid CB(1) receptors in the rat and mouse.
Q39124684Pharmacological characterisation of cannabinoid receptors inhibiting interleukin 2 release from human peripheral blood mononuclear cells
Q34078746Pharmacological characterization of cannabinoid receptor activity in the rat-isolated ileum myenteric plexus-longitudinal muscle preparation
Q34532228Pharmacological characterization of endocannabinoid transport and fatty acid amide hydrolase inhibitors
Q39791746Pharmacological characterization of repeated administration of the first generation abused synthetic cannabinoid CP47,497.
Q44457651Pharmacological effects of cannabinoids on the reference and working memory functions in mice.
Q44873529Pharmacological evaluation of aerosolized cannabinoids in mice
Q34125281Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ(9)-tetrahydrocannabinol
Q34442847Pharmacology of cannabinoid CB1 and CB2 receptors.
Q28241318Pharmacotherapeutic modulation of the endocannabinoid signalling system in psychiatric disorders: drug-discovery strategies
Q42828953Phosphatidylinositol transfer protein alpha regulates growth and apoptosis of NIH3T3 cells: involvement of a cannabinoid 1-like receptor
Q44070866Physiochemical and pharmacological characterization of a Delta(9)-THC aerosol generated by a metered dose inhaler
Q90479312Phytocannabinoids: Useful Drugs for the Treatment of Obesity? Special Focus on Cannabidiol
Q78727774Plant-derived, synthetic and endogenous cannabinoids as neuroprotective agents. Non-psychoactive cannabinoids, 'entourage' compounds and inhibitors of N-acyl ethanolamine breakdown as therapeutic strategies to avoid pyschotropic effects
Q60474559Possible Therapeutic Doses of Cannabinoid Type 1 Receptor Antagonist Reverses Key Alterations in Fragile X Syndrome Mouse Model
Q34430635Possible mechanisms of cannabinoid-induced antinociception in the spinal cord
Q34103173Potential antipsychotic properties of central cannabinoid (CB1) receptor antagonists
Q90248156Potential of Cannabinoid Receptor Ligands as Treatment for Substance Use Disorders
Q73922926Potentiation of anandamide hypotension by the transport inhibitor, AM404
Q44344808Potentiation of delta 9-tetrahydrocannabinol-induced analgesia by morphine in mice: involvement of mu- and kappa-opioid receptors
Q95372566Preface
Q44359168Preferential effects of the cannabinoid CB1 receptor antagonist, SR 141716, on food intake and body weight gain of obese (fa/fa) compared to lean Zucker rats.
Q37226537Prejunctional and peripheral effects of the cannabinoid CB(1) receptor inverse agonist rimonabant (SR 141716).
Q82183867Presence of the cannabinoid receptors, CB1 and CB2, in human omental and subcutaneous adipocytes
Q36936358Present and future therapeutic strategies in non-alcoholic fatty liver disease
Q28144567Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons
Q42707987Prevention by the cannabinoid antagonist, SR141716A, of cannabinoid‐mediated blockade of long‐term potentiation in the rat hippocampal slice
Q34397288Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.
Q40460866Prevention of plasticity of endocannabinoid signaling inhibits persistent limbic hyperexcitability caused by developmental seizures.
Q90083272Probing the CB1 Cannabinoid Receptor Binding Pocket with AM6538, a High-Affinity Irreversible Antagonist
Q37372676Production and physiological actions of anandamide in the vasculature of the rat kidney.
Q44368383Prostaglandin E2 attenuates SR141716A-precipitated withdrawal in tetrahydrocannabinol-dependent mice
Q42618328Purine receptor‐mediated endocannabinoid production and retrograde synaptic signalling in the cerebellar cortex
Q30495206Pursuing paradoxical proconvulsant prophylaxis for epileptogenesis
Q35142614Quantification of Rimonabant (SR 141716A) in Monkey Plasma Using HPLC with UV Detection
Q33659650Quantitative in vitro and in vivo pharmacological profile of CE-178253, a potent and selective cannabinoid type 1 (CB1) receptor antagonist.
Q44264992R+-methanandamide inhibits tracheal response to endogenously released acetylcholine via capsazepine-sensitive receptors
Q43812195Rapid tolerance to Delta(9)-tetrahydrocannabinol and cross-tolerance between ethanol and Delta(9)-tetrahydrocannabinol in mice
Q38458891Rational Modification of the Biological Profile of GPCR Ligands through Combination with Other Biologically Active Moieties
Q41139951Receptor mediation in cannabinoid stimulated arachidonic acid mobilization and anandamide synthesis
Q43597369Receptor-independent effects of natural cannabinoids in rat peritoneal mast cells in vitro
Q28363073Reduction of opioid dependence by the CB(1) antagonist SR141716A in mice: evaluation of the interest in pharmacotherapy of opioid addiction
Q33604478Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cells
Q41002898Regulation of delta opioid receptors by delta9-tetrahydrocannabinol in NG108-15 hybrid cells
Q40943005Regulation of peripheral cannabinoid receptor CB2 phosphorylation by the inverse agonist SR 144528. Implications for receptor biological responses
Q48198217Relationships between ligand affinities for the cerebellar cannabinoid receptor CB1 and the induction of GDP/GTP exchange
Q48559047Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain
Q43867242Reversal of SR 141716A-induced head-twitch and ear-scratch responses in mice by delta 9-THC and other cannabinoids
Q43867297Reversal of delta 9-THC hyperphagia by SR141716 and naloxone but not dexfenfluramine
Q73704501Reversal of dopamine D(2) receptor responses by an anandamide transport inhibitor
Q46484350Reversal of visceral adiposity in candy-diet fed female Wistar rats by the CB1 receptor antagonist rimonabant
Q60486616Rimonabant
Q41991321Rimonabant (SR141716) exerts anti-proliferative and immunomodulatory effects in human peripheral blood mononuclear cells
Q24634816Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm
Q42794549Rimonabant attenuates sensitization, cross-sensitization and cross-reinstatement of place preference induced by nicotine and ethanol
Q81099416Rimonabant blocks the expression but not the development of locomotor sensitization to nicotine in rats
Q37729882Rimonabant inhibits TNF-α-induced endothelial IL-6 secretion via CB1 receptor and cAMP-dependent protein kinase pathway
Q34054143Rimonabant is a dual inhibitor of acyl CoA:cholesterol acyltransferases 1 and 2.
Q39650051Rimonabant reduces keratinocyte viability by induction of apoptosis and exerts topical anti-inflammatory activity in mice
Q37862977Rimonabant redux and strategies to improve the future outlook of CB1 receptor neutral-antagonist/inverse-agonist therapies
Q36407318Rimonabant: a selective blocker of the cannabinoid CB1 receptors for the management of obesity, smoking cessation and cardiometabolic risk factors
Q37483205Rimonabant: an antagonist drug of the endocannabinoid system for the treatment of obesity
Q46900606Rimonabant: the role of endocannabinoid type 1 receptor antagonism in modulating the weight and lipid profile of obese patients
Q43263256Role of cannabinoid CB1 receptors and tumor necrosis factor-alpha in the gut and systemic anti-inflammatory activity of SR 141716 (rimonabant) in rodents
Q37345943Role of cannabinoid receptors in the control of gastrointestinal motility and perception
Q92613057Role of microRNA in CB1 antagonist-mediated regulation of adipose tissue macrophage polarization and chemotaxis during diet-induced obesity
Q53939742Role of non-nitric oxide non-prostaglandin endothelium-derived relaxing factor(s) in bradykinin vasodilation.
Q90325053Role of the Endocannabinoid System in the Pathophysiology of Schizophrenia: Implications for Pharmacological Intervention
Q46896371Role of the cannabinoid system in the effects induced by nicotine on anxiety-like behaviour in mice
Q44865127Role of the endogenous cannabinoid system as a modulator of dopamine transmission: implications for Parkinson's disease and schizophrenia
Q43503399Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat.
Q60155183Role of the superior colliculus in the motor effects of cannabinoids and dopamine
Q47628019SR 141716A, a cannabinoid receptor antagonist, produces hyperalgesia in untreated mice
Q44176704SR-141716A-induced stimulation of locomotor activity. A structure-activity relationship study
Q42445979SR141716A is an inverse agonist at the human cannabinoid CB1 receptor
Q51375099Self-administration behavior is maintained by the psychoactive ingredient of marijuana in squirrel monkeys.
Q47987506Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in drug-naive mice
Q28346418Separation of cannabinoid receptor affinity and efficacy in delta-8-tetrahydrocannabinol side-chain analogues
Q99407998Sex and Strain Variation in Initial Sensitivity and Rapid Tolerance to Δ9-Tetrahydrocannabinol
Q28363046Signal transduction pathways involved in kinin B(2) receptor-mediated vasodilation in the rat isolated perfused kidney
Q24309197Similar in vitro pharmacology of human cannabinoid CB1 receptor variants expressed in CHO cells
Q37210189Single and multiple doses of rimonabant antagonize acute effects of smoked cannabis in male cannabis users
Q38115668Sphingosine lysolipids in the CNS: endogenous cannabinoid antagonists or a parallel pain modulatory system?
Q35035850Spinal and peripheral mechanisms of cannabinoid antinociception: behavioral, neurophysiological and neuroanatomical perspectives
Q43562046Spontaneous and precipitated withdrawal with a synthetic cannabinoid, WIN 55212-2.
Q28374277Stimulation of peripheral cannabinoid receptor CB2 induces MCP-1 and IL-8 gene expression in human promyelocytic cell line HL60
Q42713279Stratification of Cannabinoid 1 Receptor (CB1R) Agonist Efficacy: Manipulation of CB1R Density through Use of Transgenic Mice Reveals Congruence between In Vivo and In Vitro Assays
Q89539285Structural Optimization of the Diarylurea PSNCBAM-1, an Allosteric Modulator of Cannabinoid Receptor 1
Q34152254Structural and pharmacological analysis of O-2050, a putative neutral cannabinoid CB(1) receptor antagonist.
Q41214405Structural features of the central cannabinoid CB1 receptor involved in the binding of the specific CB1 antagonist SR 141716A.
Q57469299Structure-Based Identification of Potent Natural Product Chemotypes as Cannabinoid Receptor 1 Inverse Agonists
Q28346456Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens
Q24555807Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
Q34374106Suppressing effect of the cannabinoid CB1 receptor antagonist, SR147778, on alcohol intake and motivational properties of alcohol in alcohol-preferring sP rats
Q36358712Supraspinal modulation of pain by cannabinoids: the role of GABA and glutamate
Q34320289Surinabant, a selective cannabinoid receptor type 1 antagonist, inhibits Δ9-tetrahydrocannabinol-induced central nervous system and heart rate effects in humans
Q44867023Synergistic interactions of endogenous opioids and cannabinoid systems
Q53012810Synthesis and 11C-Radiolabelling of 2-Carboranyl Benzothiazoles.
Q37074591Synthesis and CB1 cannabinoid receptor affinity of 4-alkoxycarbonyl-1,5-diaryl-1,2,3-triazoles
Q41855701Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice
Q34264537Synthesis and testing of novel phenyl substituted side-Chain analogues of classical cannabinoids
Q36984451Synthesis, ex vivo evaluation, and radiolabeling of potent 1,5-diphenylpyrrolidin-2-one cannabinoid subtype-1 receptor ligands as candidates for in vivo imaging
Q41428934Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice
Q47920779THC Treatment Alters Glutamate Receptor Gene Expression in Human Stem Cell-Derived Neurons
Q28271125TRPV1 and CB(1) receptor-mediated effects of the endovanilloid/endocannabinoid N-arachidonoyl-dopamine on primary afferent fibre and spinal cord neuronal responses in the rat
Q33960904Tetrahydrocannabinol and endocannabinoids in feeding and appetite
Q34360054Tetrahydrocannabinolic acid reduces nausea-induced conditioned gaping in rats and vomiting in Suncus murinus
Q38319183The CB1 cannabinoid receptor can sequester G-proteins, making them unavailable to couple to other receptors
Q35045001The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions
Q64070160The Cannabinoid CB1 Antagonist TM38837 With Limited Penetrance to the Brain Shows Reduced Fear-Promoting Effects in Mice
Q30486707The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors
Q38659944The Endocannabinoid Signaling System in the CNS: A Primer.
Q38974429The Role of Cannabinoid Receptors in the Descending Modulation of Pain
Q35028088The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery
Q40817229The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism
Q83898066The agonists for nociceptors are ubiquitous, but the modulators are specific: P2X receptors in the sensory neurons are modulated by cannabinoids
Q36961414The cannabinoid CB(1) receptor antagonist CE prolongs spatial memory duration in a rat delayed radial arm maze memory task
Q43723090The cannabinoid CB(1) receptor antagonist SR141716A increases norepinephrine outflow in the rat anterior hypothalamus
Q52047485The cannabinoid CB1 antagonist AM 251 produces food avoidance and behaviors associated with nausea but does not impair feeding efficiency in rats.
Q43791910The cannabinoid CB1 receptor antagonist SR 141716A reverses the antiemetic and motor depressant actions of WIN 55, 212-2.
Q35029262The cannabinoid CB1 receptor antagonist, SR141716A, selectively facilitates nociceptive responses of dorsal horn neurones in the rat.
Q36977773The cannabinoid CB1 receptor antagonist, rimonabant, as a promising pharmacotherapy for alcohol dependence: preclinical evidence
Q41155236The cannabinoid CB1 receptor inverse agonist AM 251 and antagonist AM 4113 produce similar effects on the behavioral satiety sequence in rats.
Q48482096The cannabinoid agonist Win55,212-2 inhibits calcium channels by receptor-mediated and direct pathways in cultured rat hippocampal neurons
Q36492788The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55.
Q42607871The cannabinoid receptor antagonist SR-141716 does not readily antagonize open-field effects induced by the cannabinoid receptor agonist (R)-methanandamide in rats
Q34159121The cannabinoid receptors.
Q34040002The cannabinoid system and cytokine network
Q35213813The cannabinoid system and immune modulation
Q36655240The cannabinoid system and its pharmacological manipulation--a review, with emphasis upon the uptake and hydrolysis of anandamide
Q84616297The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant's antiobesity effects in mice
Q44867675The discovery of endogenous cannabinoids
Q82448643The discovery of novel indole-2-carboxamides as cannabinoid CB1 receptor antagonists
Q24643876The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin
Q44494968The effect of cannabinoid receptor antagonism with SR141716A on antinociception induced by cocaine and the NMDA receptor antagonist, MK-801.
Q48094949The effects of beta-arrestin1 deletion on acute cannabinoid activity, brain cannabinoid receptors and tolerance to cannabinoids in mice.
Q28137626The effects of cannabinoids on the brain
Q47567233The effects of fasting duration on gastric emptying in man, an exploration of the role of the endocannabinoid system and inter-individual responsiveness
Q46213429The effects of rimonabant on brown adipose tissue in rat: implications for energy expenditure.
Q33790150The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels
Q36977769The endocannabinoid system and extinction learning
Q35876026The endocannabinoid system and its therapeutic exploitation
Q34626755The endocannabinoid system and rimonabant: a new drug with a novel mechanism of action involving cannabinoid CB1 receptor antagonism--or inverse agonism--as potential obesity treatment and other therapeutic use.
Q33934278The endocannabinoid system as a target for therapeutic drugs.
Q24648473The endocannabinoid system as an emerging target of pharmacotherapy
Q36741861The endocannabinoid system in brain reward processes
Q36394348The endocannabinoid system: a new approach to control cardiovascular disease
Q36701773The endocannabinoid system: body weight and metabolic regulation
Q35954057The endocannabinoid system: physiology and pharmacology.
Q36926051The endogenous cannabinoid anandamide and its synthetic analog R(+)-methanandamide are intravenously self-administered by squirrel monkeys
Q34066911The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation.
Q41048004The endogenous cannabinoid anandamide is a lipid messenger activating cell growth via a cannabinoid receptor-independent pathway in hematopoietic cell lines
Q45753821The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway
Q28280255The endogenous cannabinoid system and drug addiction: 20 years after the discovery of the CB1 receptor
Q34786832The endogenous cannabinoid system and the basal ganglia. biochemical, pharmacological, and therapeutic aspects.
Q44085607The endogenous cannabinoid system controls extinction of aversive memories
Q54363472The hypothermic response to bacterial lipopolysaccharide critically depends on brain CB1, but not CB2 or TRPV1, receptors.
Q24522320The neurobiology and evolution of cannabinoid signalling
Q28645703The peripheral cannabinoid receptor: adenylate cyclase inhibition and G protein coupling
Q43619986The pharmacological activity of inhalation exposure to marijuana smoke in mice
Q34990771The psychiatric side-effects of rimonabant
Q34472972The relationship of in vivo central CB1 receptor occupancy to changes in cortical monoamine release and feeding elicited by CB1 receptor antagonists in rats
Q28085261The role of cannabinoids in adult neurogenesis
Q34268475The role of cannabinoids in neurodegenerative diseases
Q36434442The role of the endocannabinoid system in the control of energy homeostasis.
Q37913717The role of the endocannabinoid system in the neuroendocrine regulation of energy balance.
Q45104866The selective cannabinoid antagonist SR 141716A blocks cannabinoid-induced antinociception in rats
Q37402927The therapeutic potential of novel cannabinoid receptors
Q26996134The thrifty lipids: endocannabinoids and the neural control of energy conservation
Q71769876The uterus is a potential site for anandamide synthesis and hydrolysis: differential profiles of anandamide synthase and hydrolase activities in the mouse uterus during the periimplantation period
Q36187065Therapeutic potential of cannabinoid receptor agonists as analgesic agents
Q33964721Therapeutic potential of cannabinoids in CNS disease
Q44874932Time course for the induction and maintenance of tolerance to Delta(9)-tetrahydrocannabinol in mice
Q48683075Time course of the effects of different cannabimimetics on prolactin and gonadotrophin secretion: evidence for the presence of CB1 receptors in hypothalamic structures and their involvement in the effects of cannabimimetics
Q44551331Tolerance to the memory disruptive effects of cannabinoids involves adaptation by hippocampal neurons
Q37086961Topical WIN55212-2 alleviates intraocular hypertension in rats through a CB1 receptor mediated mechanism of action
Q60228969Toward the design of cannabinoid CB1 receptor inverse agonists and neutral antagonists
Q33906007Towards cannabinoid drugs--revisited.
Q46848662Transdermal delivery of the synthetic cannabinoid WIN 55,212-2: in vitro/in vivo correlation
Q44241696Tricyclic pyrazoles. Part 1: synthesis and biological evaluation of novel 1,4-dihydroindeno[1,2-c]pyrazol-based ligands for CB1and CB2 cannabinoid receptors.
Q44334367Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus.
Q33302186Understanding cannabinoid psychoactivity with mouse genetic models
Q86924782Unique effects of compounds active at both cannabinoid and serotonin receptors during stroke
Q37556938Updates in reproduction coming from the endocannabinoid system.
Q38248001Using the endocannabinoid system as a neuroprotective strategy in perinatal hypoxic-ischemic brain injury
Q38756777Vanilloid VR1 receptor is involved in rimonabant-induced neuroprotection
Q41105693Vascular Dysfunction in a Transgenic Model of Alzheimer's Disease: Effects of CB1R and CB2R Cannabinoid Agonists
Q36358729Vascular pharmacology of a novel cannabinoid-like compound, 3-(5-dimethylcarbamoyl-pent-1-enyl)-N-(2-hydroxy-1-methyl-ethyl)benzamide (VSN16) in the rat.
Q79964935Vasorelaxant effect of Win 55,212-2 in rat aorta: new mechanisms involved
Q77291037Watching the pot boil
Q34411768Will the new CB1 cannabinoid receptor antagonist SR-147778 have advantages over rimonabant?
Q74501955[The pharmacology of cannabinoid derivatives: are there applications to treatment of pain?]
Q42439738delta 9-Tetrahydrocannabinol increases activity of tyrosine hydroxylase in cultured fetal mesencephalic neurons.
Q44345904delta9-Tetrahydrocannabinol excites rat VTA dopamine neurons through activation of cannabinoid CB1 but not opioid receptors
Q60948556∆-Tetrahydrocannabinol, a major marijuana component, enhances the anesthetic effect of pentobarbital through the CB receptor

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