| scholarly article | Q13442814 |
| P356 | DOI | 10.1158/0008-5472.CAN-04-3619 |
| P698 | PubMed publication ID | 15805274 |
| P2093 | author name string | Liwei Wang | |
| Tsung-Teh Wu | |||
| Masashi Kanai | |||
| Daoyan Wei | |||
| Keping Xie | |||
| Suyun Huang | |||
| James C Yao | |||
| Weida Gong | |||
| Christian Schlunk | |||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2746-2754 | |
| P577 | publication date | 2005-04-01 | |
| P1433 | published in | Cancer Research | Q326097 |
| P1476 | title | Drastic down-regulation of Krüppel-like factor 4 expression is critical in human gastric cancer development and progression | |
| P478 | volume | 65 |
| Q36932062 | 5,5'-Dibromo-bis(3'-indolyl)methane induces Kruppel-like factor 4 and p21 in colon cancer cells |
| Q34052691 | A novel KLF4/LDHA signaling pathway regulates aerobic glycolysis in and progression of pancreatic cancer |
| Q36238466 | A peroxisome proliferator-activated receptor ligand MCC-555 imparts anti-proliferative response in pancreatic cancer cells by PPARgamma-independent up-regulation of KLF4. |
| Q49372792 | Aging and the Krüppel-like factors |
| Q42225381 | Altered expression of Krüppel-like factor 4 and β-catenin in human gastric cancer |
| Q34149262 | Altered intestinal epithelial homeostasis in mice with intestine-specific deletion of the Krüppel-like factor 4 gene |
| Q39643637 | An embryo-specific expressing TGF-β family protein, growth-differentiation factor 3 (GDF3), augments progression of B16 melanoma |
| Q42743106 | Antiproliferative effect of estrogen in vascular smooth muscle cells is mediated by Kruppel-like factor-4 and manganese superoxide dismutase |
| Q34501671 | Association of Kruppel-like factor 4 expression with the prognosis of esophageal squamous cell carcinoma patients. |
| Q40190855 | Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer |
| Q34826101 | Attenuation of krüppel-like factor 4 facilitates carcinogenesis by inducing g1/s phase arrest in clear cell renal cell carcinoma |
| Q38851262 | Augmented miR-10b expression associated with depressed expression of its target gene KLF4 involved in gastric carcinoma. |
| Q38742982 | BMP4 promotes a phenotype change of an esophageal squamous epithelium via up-regulation of KLF4. |
| Q36497247 | CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling |
| Q34921599 | Cancer stem cells, cancer cell plasticity and radiation therapy |
| Q46678343 | Comparison of (-)-epigallocatechin-3-gallate elicited liver and small intestine gene expression profiles between C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice. |
| Q39001358 | Concomitant upregulation of nucleostemin and downregulation of Sox2 and Klf4 in gastric adenocarcinoma. |
| Q30440313 | Conditional deletion of Krüppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury |
| Q28595100 | Conditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cells |
| Q34243311 | Critical and reciprocal regulation of KLF4 and SLUG in transforming growth factor β-initiated prostate cancer epithelial-mesenchymal transition |
| Q93065274 | DNA Methylation Readers and Cancer: Mechanistic and Therapeutic Applications |
| Q50918212 | DNA-Methyltransferase 1 Induces Dedifferentiation of Pancreatic Cancer Cells through Silencing of Krüppel-Like Factor 4 Expression. |
| Q37619815 | Decreased Dp71 expression is associated with gastric adenocarcinoma prognosis |
| Q53248252 | Decreased Kruppel-like factor 4 (KLF4) expression may correlate with poor survival in gastric adenocarcinoma. |
| Q99638475 | Deoxycholic Acid Upregulates the Reprogramming Factors KFL4 and OCT4 Through the IL-6/STAT3 Pathway in Esophageal Adenocarcinoma Cells |
| Q37365730 | Differential roles of KLF4 in the development and differentiation of CD8+ T cells. |
| Q35797164 | Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial Cells |
| Q36336785 | Disruption of Klf4 in villin-positive gastric progenitor cells promotes formation and progression of tumors of the antrum in mice |
| Q34358346 | Dopamine, by Acting through Its D2 Receptor, Inhibits Insulin-Like Growth Factor-I (IGF-I)-Induced Gastric Cancer Cell Proliferation via Up-Regulation of Krüppel-Like Factor 4 through Down-Regulation of IGF-IR and AKT Phosphorylation |
| Q53321350 | Downregulation of Krüppel-like factor 9 in human colorectal cancer. |
| Q51062285 | Downregulation of the KLF4 transcription factor inhibits the proliferation and migration of canine mammary tumor cells. |
| Q46761462 | Dynamic down-regulation of Krüppel-like factor 4 in colorectal adenoma-carcinoma sequence |
| Q36843499 | Dysregulated Krüppel-like factor 4 and vitamin D receptor signaling contribute to progression of hepatocellular carcinoma |
| Q36986150 | Dysregulated expression of FOXM1 isoforms drives progression of pancreatic cancer |
| Q34042124 | Elevated Krüppel-like factor 4 transcription factor in canine mammary carcinoma |
| Q38155818 | Embryonic stem cell-specific signature in cervical cancer. |
| Q39120647 | Epigallocatechin-3-gallate regulates the expression of Kruppel-like factor 4 through myocyte enhancer factor 2A |
| Q64101598 | Epigenetic Field Cancerization in Gastric Cancer: microRNAs as Promising Biomarkers |
| Q61818546 | Epigenetic Mechanisms Influencing Epithelial to Mesenchymal Transition in Bladder Cancer |
| Q39145565 | Epigenetic alterations of Krüppel-like factor 4 and its tumor suppressor function in renal cell carcinoma |
| Q37127375 | Epigenetic contributions to cancer metastasis |
| Q64946483 | Epigenetics of oral and oropharyngeal cancers. |
| Q37313427 | Expression and Function of Kruppel Like-Factors (KLF) in Carcinogenesis |
| Q33723841 | Expression of Krüppel-like factor 4 in breast cancer tissues and its effects on the proliferation of breast cancer MDA-MB-231 cells |
| Q63384184 | Expression of mTert in primary murine cells links the growth-promoting effects of telomerase to transforming growth factor-β signaling |
| Q39752244 | Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma. |
| Q33881932 | Genetic deletion of Klf4 in the mouse intestinal epithelium ameliorates dextran sodium sulfate-induced colitis by modulating the NF-κB pathway inflammatory response |
| Q37824622 | Genomic and epigenetic profiles of gastric cancer: potential diagnostic and therapeutic applications |
| Q34541633 | HDAC1 and Klf4 interplay critically regulates human myeloid leukemia cell proliferation |
| Q28592219 | Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis |
| Q89526083 | Helicobacter pylori infection leads to KLF4 inactivation in gastric cancer through a TET1-mediated DNA methylation mechanism |
| Q89473690 | Helicobacter pylori-induced miR-135b-5p promotes cisplatin resistance in gastric cancer |
| Q33990397 | High KLF4 level in normal tissue predicts poor survival in colorectal cancer patients |
| Q104130647 | Hub gene identification and prognostic model construction for isocitrate dehydrogenase mutation in glioma |
| Q97692591 | Immune checkpoint inhibitor induces cardiac injury through polarizing macrophages via modulating microRNA-34a/Kruppel-like factor 4 signaling |
| Q35576730 | Impaired autophagy in mouse embryonic fibroblasts null for Krüppel-like Factor 4 promotes DNA damage and increases apoptosis upon serum starvation |
| Q38741844 | Impairment of DYRK2 augments stem-like traits by promoting KLF4 expression in breast cancer |
| Q92407128 | Interpreting pathways to discover cancer driver genes with Moonlight |
| Q33850331 | KLF16 promotes proliferation in gastric cancer cells via regulating p21 and CDK4. |
| Q38786245 | KLF4 Is Essential for Induction of Cellular Identity Change and Acinar-to-Ductal Reprogramming during Early Pancreatic Carcinogenesis |
| Q34512099 | KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis |
| Q36787539 | KLF4 and SOX9 transcription factors antagonize β-catenin and inhibit TCF-activity in cancer cells |
| Q93025043 | KLF4 as a rheostat of osteolysis and osteogenesis in prostate tumors in the bone |
| Q37619681 | KLF4 downregulates hTERT expression and telomerase activity to inhibit lung carcinoma growth |
| Q37525801 | KLF4 functions as an activator of the androgen receptor through reciprocal feedback |
| Q37138765 | KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract |
| Q33987695 | KLF4 inhibition of lung cancer cell invasion by suppression of SPARC expression |
| Q33790710 | KLF4 is a novel candidate tumor suppressor gene in pancreatic ductal carcinoma. |
| Q42688550 | KLF4 is downregulated but not mutated during human esophageal squamous cell carcinogenesis and has tumor stage-specific functions |
| Q33809921 | KLF4 is regulated by RAS/RAF/MEK/ERK signaling through E2F1 and promotes melanoma cell growth |
| Q34547607 | KLF4 overexpression and apigenin treatment down regulated anti-apoptotic Bcl-2 proteins and matrix metalloproteinases to control growth of human malignant neuroblastoma SK-N-DZ and IMR-32 cells |
| Q37119878 | KLF4 regulation in intestinal epithelial cell maturation |
| Q35615876 | KLF4 suppresses transformation of pre-B cells by ABL oncogenes |
| Q84149161 | KLF4 translation level is associated with differentiation stage of different pediatric leukemias in both cell lines and primary samples |
| Q58768405 | KLF4, a miR-32-5p targeted gene, promotes cisplatin-induced apoptosis by upregulating BIK expression in prostate cancer |
| Q34478868 | KLF4, p21 and context-dependent opposing forces in cancer |
| Q38793918 | KLF4-Mediated Suppression of CD44 Signaling Negatively Impacts Pancreatic Cancer Stemness and Metastasis |
| Q35023925 | KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis |
| Q35633784 | KLF4α Up-regulation Promotes Cell Cycle Progression and Reduces Survival Time of Patients With Pancreatic Cancer |
| Q33820616 | KLF6 inhibited oral cancer migration and invasion via downregulation of mesenchymal markers and inhibition of MMP-9 activities |
| Q34603384 | Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8). |
| Q47139880 | Klf4 reduces stemness phenotype, triggers mesenchymal-epithelial transition (MET)-like molecular changes, and prevents tumor progression in nasopharygeal carcinoma |
| Q34939838 | Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion |
| Q36787443 | Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells |
| Q36628945 | Kruppel-like factor 4 is a novel mediator of selenium in growth inhibition |
| Q36627270 | Krüppel-Like Factor 4 (KLF4) Is Not Required for Retinal Cell Differentiation |
| Q49788447 | Krüppel-like Factor 4 Suppresses Serine/Threonine Kinase 33 Activation and Metastasis of Gastric Cancer through Reversing Epithelial-Mesenchymal Transition. |
| Q36843752 | Krüppel-like factor 2 promotes cell proliferation in hepatocellular carcinoma through up-regulation of c-myc |
| Q39263949 | Krüppel-like factor 4 (KLF4) suppresses neuroblastoma cell growth and determines non-tumorigenic lineage differentiation. |
| Q39151066 | Krüppel-like factor 4 (KLF4): What we currently know |
| Q38655707 | Krüppel-like factor 4 acts as a potential therapeutic target of Sijunzi decoction for treatment of colorectal cancer |
| Q51104022 | Krüppel-like factor 4 contributes to the pathogenesis of mantle cell lymphoma. |
| Q36438918 | Krüppel-like factor 4 exhibits antiapoptotic activity following gamma-radiation-induced DNA damage |
| Q35915116 | Krüppel-like factor 4 expression in oral carcinoma cells and hypermethylation at the gene promoter |
| Q39428352 | Krüppel-like factor 4 functions as a tumor suppressor in cervical carcinoma |
| Q35095237 | Krüppel-like factor 4 inhibits tumorigenic progression and metastasis in a mouse model of breast cancer. |
| Q43061010 | Krüppel-like factor 4 mediates anti-proliferative effects of progesterone with G₀/G₁ arrest in human endometrial epithelial cells |
| Q33990560 | Krüppel-like factor 4 mediates lysophosphatidic acid-stimulated migration and proliferation of PC3M prostate cancer cells |
| Q37327643 | Krüppel-like factor 4 promotes human osteosarcoma growth and metastasis via regulating CRYAB expression |
| Q48819440 | Krüppel-like factor 4 regulates blood-tumor barrier permeability via ZO-1, occludin and claudin-5. |
| Q21245753 | Krüppel-like factor 4 regulates genetic stability in mouse embryonic fibroblasts |
| Q34399237 | Krüppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression |
| Q37001925 | Krüppel-like factor 4: A new potential biomarker of lung cancer |
| Q39268896 | Krüppel-like factor 8 is a novel androgen receptor co-activator in human prostate cancer |
| Q37761837 | Krüppel-like factors 4 and 5: unity in diversity |
| Q38141516 | Krüppel-like factors in cancer |
| Q38178811 | Krüppel-like factors in cancer progression: three fingers on the steering wheel |
| Q38344470 | Krüppel-like factors in hepatocellular carcinoma |
| Q93006628 | LncRNA NKILA regulates endothelium inflammation by controlling a NF-κB/KLF4 positive feedback loop |
| Q33886706 | MCC-555-induced NAG-1 expression is mediated in part by KLF4. |
| Q24612560 | Mammalian Krüppel-Like Factors in Health and Diseases |
| Q58744702 | Methylation status of KLF4 and HS3ST2 genes as predictors of endometrial cancer and hyperplastic endometrial lesions |
| Q33779355 | MiR-145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells |
| Q38847978 | MiR-375 targets KLF4 and impacts the proliferation of colorectal carcinoma |
| Q27316708 | MiR-7 promotes epithelial cell transformation by targeting the tumor suppressor KLF4 |
| Q48242100 | MicroRNA-10b regulates the renewal of spermatogonial stem cells through Kruppel-like factor 4. |
| Q37507386 | MicroRNA-29a promotes colorectal cancer metastasis by regulating matrix metalloproteinase 2 and E-cadherin via KLF4 |
| Q64070951 | Monomethyltransferase SET8 facilitates hepatocellular carcinoma growth by enhancing aerobic glycolysis |
| Q34919738 | Mouse embryonic fibroblasts null for the Krüppel-like factor 4 gene are genetically unstable |
| Q37061732 | Mouse models of gastric cancer. |
| Q37594950 | Murine Models of Gastric Corpus Preneoplasia. |
| Q89285891 | Negative Regulation of Kruppel-Like Factor 4 on microRNA-106a at Upstream Transcriptional Level and the Role in Gastric Cancer Metastasis |
| Q33853834 | Nitric oxide synthase II suppresses the growth and metastasis of human cancer regardless of its up-regulation of protumor factors |
| Q34519910 | Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression |
| Q39289226 | Novel tumor-suppressor function of KLF4 in pediatric T-cell acute lymphoblastic leukemia |
| Q35177151 | Nuclear factor I-C regulates E-cadherin via control of KLF4 in breast cancer |
| Q31055386 | On the statistical assessment of classifiers using DNA microarray data |
| Q40097721 | Over-expression of FRZB in gastric cancer cell suppresses proliferation and induces differentiation |
| Q38999451 | Oxidative DNA damage causes premature senescence in mouse embryonic fibroblasts deficient for Krüppel-like factor 4. |
| Q39610176 | Persistent Krüppel-like factor 4 expression predicts progression and poor prognosis of head and neck squamous cell carcinoma |
| Q85895132 | Phase 1 study of APTO-253 HCl, an inducer of KLF4, in patients with advanced or metastatic solid tumors |
| Q37122739 | Pluripotency and nuclear reprogramming |
| Q39727817 | Potential utility of HOP homeobox gene promoter methylation as a marker of tumor aggressiveness in gastric cancer |
| Q38868138 | Prognostic significance of KLF4 expression in gastric cancer |
| Q24617620 | Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration |
| Q35097588 | Promoter hypermethylation of KLF4 inactivates its tumor suppressor function in cervical carcinogenesis |
| Q35001648 | Putative tumor-suppressive function of Kruppel-like factor 4 in primary lung carcinoma |
| Q61446457 | Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traits |
| Q34021751 | Regulation of EMT by KLF4 in gastrointestinal cancer |
| Q47097615 | Restoration of KLF4 Inhibits Invasion and Metastases of Lung Adenocarcinoma through Suppressing MMP2. |
| Q47109366 | Role of Krüppel-like factor 4 and heat shock protein 27 in cancer of the larynx. |
| Q55077620 | Role of Krüppel-like factor 4 in cigarette smoke-induced pulmonary vascular remodeling. |
| Q37406509 | Role of peptidylarginine deiminase type 4 in gastric cancer |
| Q38747777 | Role of the reprogramming factor KLF4 in blood formation |
| Q37158208 | Roles of Krüpel-like factor 4 in normal homeostasis, cancer and stem cells |
| Q58779082 | SOX2 recruits KLF4 to regulate nasopharyngeal carcinoma proliferation via PI3K/AKT signaling |
| Q39214035 | SP and KLF Transcription Factors in Digestive Physiology and Diseases |
| Q27027153 | Stem cells in gastric cancer |
| Q34523065 | Suppression of epithelial-mesenchymal transition in hepatocellular carcinoma cells by Krüppel-like factor 4. |
| Q36689015 | The Janus-faced roles of Krüppel-like factor 4 in oral squamous cell carcinoma cells |
| Q34462232 | The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene |
| Q49658179 | The Novel KLF4/MSI2 Signaling Pathway Regulates Growth and Metastasis of Pancreatic Cancer |
| Q43372975 | The Prognostic Value of Decreased KLF4 in Digestive System Cancers: A Meta-Analysis from 17 Studies |
| Q33652886 | The Transcription Regulator Krüppel-Like Factor 4 and Its Dual Roles of Oncogene in Glioblastoma and Tumor Suppressor in Neuroblastoma |
| Q24647882 | The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology |
| Q55314501 | The novel KLF4/PLAC8 signaling pathway regulates lung cancer growth. |
| Q26768676 | The role of pluripotency factors to drive stemness in gastrointestinal cancer |
| Q42431719 | The specific inhibition of HepG2 cells proliferation by apoptosis induced by gabexate mesilate |
| Q35929818 | Transcription factor KLF4 regulates microRNA-544 that targets YWHAZ in cervical cancer. |
| Q35112786 | Transcriptional profiling of the cell cycle checkpoint gene krüppel-like factor 4 reveals a global inhibitory function in macromolecular biosynthesis |
| Q37697215 | Transcriptional repression of FOXO1 by KLF4 contributes to glioma progression. |
| Q28074847 | Transgenic and gene knockout mice in gastric cancer research |
| Q42075849 | Transgenic mice expressing constitutively active Akt in oral epithelium validate KLFA as a potential biomarker of head and neck squamous cell carcinoma |
| Q38999422 | Upregulation of KLF4 by methylseleninic acid in human esophageal squamous cell carcinoma cells: Modification of histone H3 acetylation through HAT/HDAC interplay |
| Q55427213 | [Correlation of KLF4 and SPARC expression with the clinical characteristics of non-small cell lung cancer]. |
| Q42020455 | hsa-miR-29c and hsa-miR-135b differential expression as potential biomarker of gastric carcinogenesis. |
| Q42206395 | miR-103 Promotes Proliferation and Metastasis by Targeting KLF4 in Gastric Cancer |
| Q49681001 | miR-124 inhibits progression of hepatocarcinoma by targeting KLF4 and promises a novel diagnostic marker |
| Q52641305 | miR-25 enhances cell migration and invasion in non-small-cell lung cancer cells via ERK signaling pathway by inhibiting KLF4. |
| Q41708883 | miR-543 promotes colorectal cancer proliferation and metastasis by targeting KLF4. |
| Q38806678 | p21 and CK2 interaction-mediated HDAC2 phosphorylation modulates KLF4 acetylation to regulate bladder cancer cell proliferation |
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