scholarly article | Q13442814 |
P50 | author | Robert F. Siliciano | Q7344216 |
Robert W. Maul | Q54437945 | ||
Rahul M. Kohli | Q55189769 | ||
Huseyin Saribasak | Q55397173 | ||
P2093 | author name string | James T Stivers | |
Patricia J Gearhart | |||
Moira A McMahon | |||
Kiran S Gajula | |||
Amy F Guminski | |||
Rhonda L McClure | |||
P2860 | cites work | Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2) | Q24290325 |
Codon and amino acid usage in retroviral genomes is consistent with virus-specific nucleotide pressure | Q24498128 | ||
Mutational comparison of the single-domained APOBEC3C and double-domained APOBEC3F/G anti-retroviral cytidine deaminases provides insight into their DNA target site specificities | Q24521469 | ||
Human APOBEC3F is another host factor that blocks human immunodeficiency virus type 1 replication | Q24563503 | ||
Targeting APOBEC3A to the viral nucleoprotein complex confers antiviral activity | Q24565021 | ||
APOBEC3G contributes to HIV-1 variation through sublethal mutagenesis | Q24618320 | ||
Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications | Q24646317 | ||
Human APOBEC3G can restrict retroviral infection in avian cells and acts independently of both UNG and SMUG1 | Q24655541 | ||
Cytidine deamination induced HIV-1 drug resistance | Q24657298 | ||
Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G | Q27649897 | ||
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein | Q27860488 | ||
WebLogo: A Sequence Logo Generator | Q27860646 | ||
DNA deamination mediates innate immunity to retroviral infection | Q28179534 | ||
Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex | Q28210666 | ||
APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo | Q28275837 | ||
The retroviral hypermutation specificity of APOBEC3F and APOBEC3G is governed by the C-terminal DNA cytosine deaminase domain | Q28302167 | ||
RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1 | Q28474904 | ||
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme | Q29547201 | ||
Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome | Q29618742 | ||
APOBEC3F and APOBEC3G inhibit HIV-1 DNA integration by different mechanisms. | Q33826968 | ||
Determinants of sequence-specificity within human AID and APOBEC3G | Q33885890 | ||
HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import. | Q33887160 | ||
Human APOBEC3G-mediated editing can promote HIV-1 sequence diversification and accelerate adaptation to selective pressure | Q34120736 | ||
R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells | Q34188845 | ||
Targeting of somatic hypermutation | Q34551108 | ||
The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cells | Q35888172 | ||
Human immunodeficiency virus type 1 Vif inhibits packaging and antiviral activity of a degradation-resistant APOBEC3G variant | Q35947586 | ||
Lethal mutagenesis of HIV. | Q36008905 | ||
Enzymatically active APOBEC3G is required for efficient inhibition of human immunodeficiency virus type 1. | Q36315163 | ||
The DNA deaminase activity of human APOBEC3G is required for Ty1, MusD, and human immunodeficiency virus type 1 restriction | Q36484144 | ||
Single-stranded RNA facilitates nucleocapsid: APOBEC3G complex formation | Q36666251 | ||
Role of AID in tumorigenesis | Q36845685 | ||
Conserved footprints of APOBEC3G on Hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequences | Q36845949 | ||
Dissecting APOBEC3G substrate specificity by nucleoside analog interference. | Q37119821 | ||
APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA | Q37131958 | ||
Immunoglobulin switch mu sequence causes RNA polymerase II accumulation and reduces dA hypermutation. | Q37273168 | ||
A portable hot spot recognition loop transfers sequence preferences from APOBEC family members to activation-induced cytidine deaminase. | Q37371679 | ||
DNA targets of AID evolutionary link between antibody somatic hypermutation and class switch recombination | Q37397523 | ||
Functional analysis and structural modeling of human APOBEC3G reveal the role of evolutionarily conserved elements in the inhibition of human immunodeficiency virus type 1 infection and Alu transposition. | Q37452063 | ||
Novel single-cell-level phenotypic assay for residual drug susceptibility and reduced replication capacity of drug-resistant human immunodeficiency virus type 1. | Q38449098 | ||
Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID. | Q39756116 | ||
Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent | Q39869882 | ||
Uracil DNA glycosylase disruption blocks Ig gene conversion and induces transition mutations | Q40338305 | ||
Biochemical analysis of hypermutational targeting by wild type and mutant activation-induced cytidine deaminase | Q40515192 | ||
A quantitative assay for HIV DNA integration in vivo | Q40809319 | ||
AID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity | Q40818553 | ||
Mechanism of R-loop formation at immunoglobulin class switch sequences | Q41887873 | ||
Non-redundancy of cytidine deaminases in class switch recombination | Q44781044 | ||
Rapid evolution of primate antiviral enzyme APOBEC3G. | Q44938087 | ||
AID is required for c-myc/IgH chromosome translocations in vivo | Q45021537 | ||
Complementary function of the two catalytic domains of APOBEC3G. | Q45274484 | ||
Codon bias targets mutation. | Q59081204 | ||
Insights into DNA deaminases | Q79487889 | ||
P433 | issue | 52 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | antibody | Q79460 |
P304 | page(s) | 40956-40964 | |
P577 | publication date | 2010-10-06 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Local sequence targeting in the AID/APOBEC family differentially impacts retroviral restriction and antibody diversification | |
P478 | volume | 285 |
Q40142288 | A putative antiviral role of plant cytidine deaminases |
Q21131084 | AID and APOBECs span the gap between innate and adaptive immunity |
Q30537745 | AID and Apobec3G haphazard deamination and mutational diversity |
Q41917830 | AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation. |
Q45324625 | APOBEC Enzymes as Targets for Virus and Cancer Therapy. |
Q36759909 | APOBEC3 inhibition of mouse mammary tumor virus infection: the role of cytidine deamination versus inhibition of reverse transcription |
Q37402303 | APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma. |
Q36963205 | APOBEC3G cytosine deamination hotspots are defined by both sequence context and single-stranded DNA secondary structure |
Q38394187 | APOBECs and virus restriction |
Q28592936 | ATAD5 deficiency decreases B cell division and Igh recombination |
Q28713968 | An ancient history of gene duplications, fusions and losses in the evolution of APOBEC3 mutators in mammals |
Q36540495 | Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerases |
Q88960625 | Characterization of molecular attributes that influence LINE-1 restriction by all seven human APOBEC3 proteins |
Q36301232 | Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain |
Q36184715 | DNA cytosine and methylcytosine deamination by APOBEC3B: enhancing methylcytosine deamination by engineering APOBEC3B. |
Q36173864 | Does DNA repair occur during somatic hypermutation? |
Q41233203 | Error-prone DNA polymerase and oxidative stress increase the incidences of A to G mutations in tumors |
Q34357412 | Evidence for APOBEC3B mutagenesis in multiple human cancers |
Q49917892 | Harnessing natural DNA modifying activities for editing of the genome and epigenome. |
Q34115490 | High-throughput mutagenesis reveals functional determinants for DNA targeting by activation-induced deaminase. |
Q41562658 | Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity. |
Q59351278 | Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2'-Deoxyzebularine Analogues |
Q52621974 | Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies. |
Q36033318 | Iron inhibits activation-induced cytidine deaminase enzymatic activity and modulates immunoglobulin class switch DNA recombination |
Q37689834 | Mechanisms of base substitution mutagenesis in cancer genomes |
Q57173759 | Modeling the Embrace of a Mutator: APOBEC Selection of Nucleic Acid Ligands |
Q90598776 | Molecular analysis of γ1, γ3, and α class switch recombination junctions in APOBEC3-deficient mice using high-throughput sequencing |
Q42725143 | Molecular targeting of mutagenic AID and APOBEC deaminases |
Q37091342 | Nuclear Magnetic Resonance Structure of the APOBEC3B Catalytic Domain: Structural Basis for Substrate Binding and DNA Deaminase Activity |
Q41738413 | RNA-binding residues in the N-terminus of APOBEC3G influence its DNA sequence specificity and retrovirus restriction efficiency |
Q35068754 | Sequence and structural determinants of human APOBEC3H deaminase and anti-HIV-1 activities |
Q34375128 | Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo-activated cells |
Q37629738 | Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B. |
Q37518666 | Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties |
Q26862780 | The APOBEC3 family of retroelement restriction factors |
Q37281847 | The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis. |
Q37946460 | The curious chemical biology of cytosine: deamination, methylation, and oxidation as modulators of genomic potential. |
Q40808215 | The in vitro Biochemical Characterization of an HIV-1 Restriction Factor APOBEC3F: Importance of Loop 7 on Both CD1 and CD2 for DNA Binding and Deamination |
Q37265843 | The local dinucleotide preference of APOBEC3G can be altered from 5'-CC to 5'-TC by a single amino acid substitution. |
Q35587316 | Topoisomerase I deficiency causes RNA polymerase II accumulation and increases AID abundance in immunoglobulin variable genes |
Q36842394 | Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions |
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