| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Eugene Koonin | Q3699974 |
| P2093 | author name string | Alexander E Lobkovsky | |
| P2860 | cites work | Non-homologous isofunctional enzymes: a systematic analysis of alternative solutions in enzyme evolution | Q21093192 |
| Predictability of evolutionary trajectories in fitness landscapes | Q21145317 | ||
| Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli | Q22066316 | ||
| Microbial genetics: Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation | Q22122024 | ||
| Adaptive molecular evolution for 13,000 phage generations: a possible arms race | Q24545052 | ||
| Constraints and plasticity in genome and molecular-phenome evolution | Q24594789 | ||
| Exploring protein fitness landscapes by directed evolution | Q24630945 | ||
| Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases | Q24648100 | ||
| Sequencing technologies - the next generation | Q27860568 | ||
| The neutral theory of molecular evolution in the genomic era | Q28285816 | ||
| Evolutionary trajectories of beta-lactamase CTX-M-1 cluster enzymes: predicting antibiotic resistance | Q28472615 | ||
| Pervasive Cryptic Epistasis in Molecular Evolution | Q28475868 | ||
| Fitness trade-offs in the evolution of dihydrofolate reductase and drug resistance in Plasmodium falciparum | Q28478215 | ||
| A framework for evolutionary systems biology | Q28754894 | ||
| Orthologs, paralogs, and evolutionary genomics | Q29615399 | ||
| Darwinian evolution can follow only very few mutational paths to fitter proteins | Q29616042 | ||
| Experimental rugged fitness landscape in protein sequence space | Q33267358 | ||
| Analysis of epistatic interactions and fitness landscapes using a new geometric approach | Q33282053 | ||
| The ascent of the abundant: how mutational networks constrain evolution | Q33352684 | ||
| The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast | Q33392677 | ||
| Experimental evolution with E. coli in diverse resource environments. I. Fluctuating environments promote divergence of replicate populations | Q33523627 | ||
| Universal distribution of protein evolution rates as a consequence of protein folding physics | Q33529576 | ||
| Fitness flux and ubiquity of adaptive evolution | Q33732926 | ||
| Parallel and divergent genotypic evolution in experimental populations of Ralstonia sp | Q33736264 | ||
| Colloquium papers: Adaptive landscapes and protein evolution | Q33844420 | ||
| Initial mutations direct alternative pathways of protein evolution | Q33847781 | ||
| Fitness epistasis and constraints on adaptation in a human immunodeficiency virus type 1 protein region | Q33853183 | ||
| Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugged fitness landscape | Q33892372 | ||
| Evolutionary accessibility of mutational pathways | Q34005257 | ||
| Reciprocal sign epistasis is a necessary condition for multi-peaked fitness landscapes. | Q34155513 | ||
| Repeatability and contingency in the evolution of a key innovation in phage lambda | Q34250057 | ||
| Defining the sequence-recognition profile of DNA-binding molecules | Q34304813 | ||
| Compensatory mutations restore fitness during the evolution of dihydrofolate reductase | Q34310777 | ||
| Perspective: Sign epistasis and genetic constraint on evolutionary trajectories | Q34437784 | ||
| The biochemical architecture of an ancient adaptive landscape | Q34461523 | ||
| Mutational effects and population dynamics during viral adaptation challenge current models | Q34477455 | ||
| Different trajectories of parallel evolution during viral adaptation | Q34504264 | ||
| Robustness-epistasis link shapes the fitness landscape of a randomly drifting protein. | Q34584004 | ||
| Empirical fitness landscapes reveal accessible evolutionary paths | Q34606034 | ||
| Tests of parallel molecular evolution in a long-term experiment with Escherichia coli | Q34694847 | ||
| Constructing and analyzing the fitness landscape of an experimental evolutionary process | Q34810511 | ||
| Parallel changes in global protein profiles during long-term experimental evolution in Escherichia coli | Q35038412 | ||
| Genetic variation and the fate of beneficial mutations in asexual populations | Q35222738 | ||
| Evolutionary paths to antibiotic resistance under dynamically sustained drug selection | Q36500996 | ||
| Clonal interference, multiple mutations and adaptation in large asexual populations | Q37011413 | ||
| Directed enzyme evolution: climbing fitness peaks one amino acid at a time | Q37244268 | ||
| Stepwise acquisition of pyrimethamine resistance in the malaria parasite | Q37274346 | ||
| The genetics of adaptation for eight microvirid bacteriophages | Q37353497 | ||
| The dynamics of adaptation on correlated fitness landscapes | Q37399576 | ||
| Revealing evolutionary pathways by fitness landscape reconstruction | Q37529875 | ||
| High-throughput DNA sequencing--concepts and limitations | Q37756751 | ||
| Systems-biology approaches for predicting genomic evolution | Q37909892 | ||
| The evolutionary landscape of antifolate resistance in Plasmodium falciparum | Q37922535 | ||
| Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape | Q38358691 | ||
| Direct demonstration of an adaptive constraint | Q39344593 | ||
| DNA and the neutral theory | Q39433323 | ||
| High-resolution mapping of evolutionary trajectories in a phage | Q40015135 | ||
| Stomach lysozyme gene of the langur monkey: tests for convergence and positive selection | Q41172670 | ||
| Molecular characterization of clonal interference during adaptive evolution in asexual populations of Saccharomyces cerevisiae | Q41182739 | ||
| Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibiotics | Q41311524 | ||
| Overdominant alleles in a population of variable size. | Q41669355 | ||
| Interactions between evolutionary processes at high mutation rates | Q41986317 | ||
| The NK model of rugged fitness landscapes and its application to maturation of the immune response | Q42643980 | ||
| Predictive models for population performance on real biological fitness landscapes | Q43656975 | ||
| The interaction of genetic drift and mutation with selection in a fluctuating environment | Q44695975 | ||
| Multiple peaks and reciprocal sign epistasis in an empirically determined genotype-phenotype landscape. | Q45401948 | ||
| Zidovudine treatment results in the selection of human immunodeficiency virus type 1 variants whose genotypes confer increasing levels of drug resistance. | Q45790013 | ||
| Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus-positive subjects | Q45873929 | ||
| Comparative genome sequencing of Escherichia coli allows observation of bacterial evolution on a laboratory timescale | Q46069507 | ||
| The molecular diversity of adaptive convergence. | Q46185374 | ||
| Phylogenomics of C(4) photosynthesis in sedges (Cyperaceae): multiple appearances and genetic convergence. | Q46268012 | ||
| Exploring the effect of sex on empirical fitness landscapes | Q46501857 | ||
| Towards a general theory of adaptive walks on rugged landscapes | Q47593883 | ||
| Episodic adaptive evolution of primate lysozymes | Q48055066 | ||
| C4 Photosynthesis evolved in grasses via parallel adaptive genetic changes. | Q48078486 | ||
| Compensatory mutations are repeatable and clustered within proteins. | Q51749478 | ||
| The genetic basis of parallel and divergent phenotypic responses in evolving populations of Escherichia coli. | Q54430796 | ||
| Distributions of epistasis in microbes fit predictions from a fitness landscape model. | Q54444950 | ||
| Parallel Genetic and Phenotypic Evolution of DNA Superhelicity in Experimental Populations of Escherichia coli | Q56920018 | ||
| Adaptive evolution in the stomach lysozymes of foregut fermenters | Q70367764 | ||
| Analysis of a local fitness landscape with a model of the rough Mt. Fuji-type landscape: application to prolyl endopeptidase and thermolysin | Q73756242 | ||
| P304 | page(s) | 246 | |
| P577 | publication date | 2012-11-26 | |
| P1433 | published in | Frontiers in Genetics | Q2499875 |
| P1476 | title | Replaying the tape of life: quantification of the predictability of evolution | |
| P478 | volume | 3 |
| Q90699093 | Analysis of statistical correlations between properties of adaptive walks in fitness landscapes |
| Q89866593 | Chromosomal barcoding of E. coli populations reveals lineage diversity dynamics at high resolution |
| Q46323402 | Constraint and Contingency Pervade the Emergence of Novel Phenotypes in Complex Metabolic Systems |
| Q61799270 | Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes |
| Q60947411 | Does the Genomic Landscape of Species Divergence in Beans Coerce Parallel Signatures of Adaptation and Domestication? |
| Q38187602 | Dynamics and constraints of enzyme evolution |
| Q38218962 | Empirical fitness landscapes and the predictability of evolution |
| Q90064873 | Estimating the predictability of cancer evolution |
| Q57145362 | Evolution of bacteria specialization along an antibiotic dose gradient |
| Q31150861 | Genomic Trajectories to Desiccation Resistance: Convergence and Divergence Among Replicate Selected Drosophila Lines |
| Q92342787 | Genotype network intersections promote evolutionary innovation |
| Q43163360 | History, chance and selection during phenotypic and genomic experimental evolution: replaying the tape of life at different levels |
| Q42197694 | How mutational epistasis impairs predictability in protein evolution and design |
| Q33560343 | Laboratory selection quickly erases historical differentiation |
| Q38515559 | Metabolism at evolutionary optimal States. |
| Q26776351 | Microbial diversity--exploration of natural ecosystems and microbiomes |
| Q93101105 | Parallel evolution of HIV-1 in a long-term experiment |
| Q33680845 | Predictable phenotypic, but not karyotypic, evolution of populations with contrasting initial history |
| Q95315605 | Predictable properties of fitness landscapes induced by adaptational tradeoffs |
| Q54295384 | Predicting evolution. |
| Q41686698 | Predicting metabolic adaptation from networks of mutational paths |
| Q49980094 | Predicting species emergence in simulated complex pre-biotic networks |
| Q58769267 | Predicting the evolution of Escherichia coli by a data-driven approach |
| Q35090009 | Protein folding and binding can emerge as evolutionary spandrels through structural coupling. |
| Q35077513 | Quantifying the similarity of monotonic trajectories in rough and smooth fitness landscapes |
| Q36093084 | Recurrent selection explains parallel evolution of genomic regions of high relative but low absolute differentiation in a ring species |
| Q26774050 | Replaying the tape of life in the twenty-first century |
| Q28607370 | Reverse evolution leads to genotypic incompatibility despite functional and active site convergence |
| Q56059233 | SETI in vivo: testing the we-are-them hypothesis |
| Q46248557 | Species-specific genes under selection characterize the co-evolution of slavemaker and host lifestyles |
| Q41023000 | Stress-response balance drives the evolution of a network module and its host genome |
| Q37625859 | The adaptive potential of hybridization demonstrated with bacteriophages |
| Q59353073 | The utility of fitness landscapes and big data for predicting evolution |
| Q35787623 | Unique evolutionary trajectories in repeated adaptation to hydrogen sulphide-toxic habitats of a neotropical fish (Poecilia mexicana). |
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