Distribution of the type III DNA methyltransferases modA, modB and modD among Neisseria meningitidis genotypes: implications for gene regulation and virulence.

scientific article

Distribution of the type III DNA methyltransferases modA, modB and modD among Neisseria meningitidis genotypes: implications for gene regulation and virulence. is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1031121807
P356DOI10.1038/SREP21015
P932PMC publication ID4751487
P698PubMed publication ID26867950
P5875ResearchGate publication ID294289018

P50authorOdile B HarrisonQ55172585
Aimee TanQ56441634
Yogitha N SrikhantaQ57168216
Kate L SeibQ42328606
Martin MaidenQ42687585
P2093author name stringDorothea M C Hill
Michael P Jennings
P2860cites workComplete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58Q22065549
Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491Q22122399
Jalview Version 2--a multiple sequence alignment editor and analysis workbenchQ24655519
Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganismsQ24685491
Characterization of ST-4821 complex, a unique Neisseria meningitidis clone.Q50857953
Comparative whole-genome analyses reveal over 100 putative phase-variable genes in the pathogenic Neisseria sppQ74339153
Phase variation in meningococcal lipooligosaccharide biosynthesis genesQ78550505
Experimentally revised repertoire of putative contingency loci in Neisseria meningitidis strain MC58: evidence for a novel mechanism of phase variationQ79079901
MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony MethodsQ27860929
Meningococcal carriage and disease--population biology and evolutionQ28246008
Application of phylogenetic networks in evolutionary studiesQ28276801
A new bioinformatics analysis tools framework at EMBL-EBI.Q29547584
Resolution of a meningococcal disease outbreak from whole-genome sequence data with rapid Web-based analysis methodsQ30464193
A biphasic epigenetic switch controls immunoevasion, virulence and niche adaptation in non-typeable Haemophilus influenzaeQ30659946
The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as 'virulence genes'.Q33245141
Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18.Q33274203
Association of a bacteriophage with meningococcal disease in young adults.Q33391053
Phasevarions mediate random switching of gene expression in pathogenic NeisseriaQ33434451
Genome sequencing reveals widespread virulence gene exchange among human Neisseria speciesQ33646735
Cellular and molecular biology of Neisseria meningitidis colonization and invasive diseaseQ33696949
BIGSdb: Scalable analysis of bacterial genome variation at the population level.Q33767145
Differential distribution of novel restriction-modification systems in clonal lineages of Neisseria meningitidisQ33889686
The phasevarion: a genetic system controlling coordinated, random switching of expression of multiple genesQ33936713
Carried meningococci in the Czech Republic: a diverse recombining populationQ33970597
Metabolism and virulence in Neisseria meningitidisQ34068118
The phasevarion: phase variation of type III DNA methyltransferases controls coordinated switching in multiple genesQ34097495
Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombinationQ34168120
Origin of the diversity in DNA recognition domains in phasevarion associated modA genes of pathogenic Neisseria and Haemophilus influenzaeQ34211653
Meningococcal diseaseQ34239234
ModM DNA methyltransferase methylome analysis reveals a potential role for Moraxella catarrhalis phasevarions in otitis media.Q34436584
Specificity of the ModA11, ModA12 and ModD1 epigenetic regulator N(6)-adenine DNA methyltransferases of Neisseria meningitidis.Q34470436
Automated extraction of typing information for bacterial pathogens from whole genome sequence data: Neisseria meningitidis as an exemplar.Q34570146
Neisseria meningitidis: biology, microbiology, and epidemiology.Q34632986
Haemophilus influenzae phasevarions have evolved from type III DNA restriction systems into epigenetic regulators of gene expression.Q34659322
Role of selection in the emergence of lineages and the evolution of virulence in Neisseria meningitidisQ34836342
Where does Neisseria acquire foreign DNA from: an examination of the source of genomic and pathogenic islands and the evolution of the Neisseria genus.Q34978876
Methylome diversification through changes in DNA methyltransferase sequence specificity.Q35144970
Host genetic determinants of Neisseria meningitidis infections.Q35211292
A gene-by-gene population genomics platform: de novo assembly, annotation and genealogical analysis of 108 representative Neisseria meningitidis genomesQ35530102
Extensive genomic variation within clonal complexes of Neisseria meningitidis.Q35623008
Genomic epidemiology of age-associated meningococcal lineages in national surveillance: an observational cohort studyQ35826786
Movement of DNA sequence recognition domains between non-orthologous proteins.Q36305686
A chromosomally integrated bacteriophage in invasive meningococciQ36399953
Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in Neisseria meningitidisQ36491155
Natural genetic exchange between Haemophilus and Neisseria: intergeneric transfer of chromosomal genes between major human pathogensQ36524212
Multilocus sequence typing for global surveillance of meningococcal disease.Q36683974
Phase variable type III restriction-modification systems of host-adapted bacterial pathogensQ36917132
Homologous recombination drives both sequence diversity and gene content variation in Neisseria meningitidis.Q37208928
Population genomics: diversity and virulence in the NeisseriaQ37281265
Epidemiological evidence for the role of the hemoglobin receptor, hmbR, in meningococcal virulence.Q37316748
Global epidemiology of invasive meningococcal diseaseQ37359946
Distribution of serogroups and genotypes among disease-associated and carried isolates of Neisseria meningitidis from the Czech Republic, Greece, and NorwayQ37597599
Genetic susceptibility to meningococcal infectionQ38081495
Functional analysis of conserved motifs in EcoP15I DNA methyltransferaseQ38356849
Comparative genome biology of a serogroup B carriage and disease strain supports a polygenic nature of meningococcal virulenceQ39667409
Genetic studies of the lac repressor. VII. On the molecular nature of spontaneous hotspots in the lacI gene of Escherichia coliQ41008292
Phasevarions mediate epigenetic regulation of antimicrobial susceptibility in Neisseria meningitidis.Q41082178
Characterization of the NgoAXP: phase-variable type III restriction-modification system in Neisseria gonorrhoeae.Q43275825
The influence of mutation, recombination, population history, and selection on patterns of genetic diversity in Neisseria meningitidisQ43520723
A novel epigenetic regulator associated with the hypervirulent Neisseria meningitidis clonal complex 41/44.Q44462970
Structure-guided analysis reveals nine sequence motifs conserved among DNA amino-methyltransferases, and suggests a catalytic mechanism for these enzymesQ48069333
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectNeisseria meningitidisQ154625
P304page(s)21015
P577publication date2016-02-12
P1433published inScientific ReportsQ2261792
P1476titleDistribution of the type III DNA methyltransferases modA, modB and modD among Neisseria meningitidis genotypes: implications for gene regulation and virulence
P478volume6

Reverse relations

cites work (P2860)
Q52648650A survey of Type III restriction-modification systems reveals numerous, novel epigenetic regulators controlling phase-variable regulons; phasevarions.
Q89930481Complete genome and methylome analysis of Neisseria meningitidis associated with increased serogroup Y disease
Q58577498First genome sequencing and comparative analyses of strains from Mexico
Q90663459Genetic variation regulates the activation and specificity of Restriction-Modification systems in Neisseria gonorrhoeae
Q58596564Moraxella catarrhalis Restriction-Modification Systems are Associated with Phylogenetic Lineage and Disease
Q47875777Phase variation of DNA methyltransferases and the regulation of virulence and immune evasion in the pathogenic Neisseria
Q49917740Phasevarions of Bacterial Pathogens: Methylomics Sheds New Light on Old Enemies
Q55129339Phasome analysis of pathogenic and commensal Neisseria species expands the known repertoire of phase variable genes, and highlights common adaptive strategies.
Q57285690Streptococcus suis contains multiple phase-variable methyltransferases that show a discrete lineage distribution
Q28074750The Capricious Nature of Bacterial Pathogens: Phasevarions and Vaccine Development

Search more.