| scholarly article | Q13442814 |
| P2093 | author name string | Mei Qi | |
| Ann E Anderson | |||
| Karen J Auborn | |||
| Da-Zhi Chen | |||
| Shishinn Sun | |||
| P2860 | cites work | The lipid phosphatase activity of PTEN is critical for its tumor supressor function | Q22007981 |
| The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
| P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
| 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase | Q24336639 | ||
| Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase | Q24682825 | ||
| PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
| Molecular targets and anticancer potential of indole-3-carbinol and its derivatives | Q28265919 | ||
| Role of translocation in the activation and function of protein kinase B | Q28609902 | ||
| Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B | Q28646376 | ||
| New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway | Q29616144 | ||
| Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers. | Q34318634 | ||
| Indole-3-carbinol is a negative regulator of estrogen | Q35168718 | ||
| PTEN controls tumor-induced angiogenesis | Q35282160 | ||
| PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1. | Q35661819 | ||
| Shc and FAK differentially regulate cell motility and directionality modulated by PTEN. | Q36301565 | ||
| Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice | Q37680979 | ||
| Indole-3-carbinol inhibits CDK6 expression in human MCF-7 breast cancer cells by disrupting Sp1 transcription factor interactions with a composite element in the CDK6 gene promoter | Q38302095 | ||
| 3,3'-Diindolylmethane (DIM) induces a G(1) cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression | Q38363872 | ||
| Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN. | Q39457088 | ||
| Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. | Q40365994 | ||
| Phytoestrogen exposure elevates PTEN levels | Q40435447 | ||
| Anti-carcinogenic and anti-metastatic properties of indole-3-carbinol in prostate cancer. | Q40483775 | ||
| Endoplasmic reticulum stress as a correlate of cytotoxicity in human tumor cells exposed to diindolylmethane in vitro | Q40532508 | ||
| Inactivation of akt and NF-kappaB play important roles during indole-3-carbinol-induced apoptosis in breast cancer cells | Q40544112 | ||
| Phosphoinositide-dependent kinase-2 is a distinct protein kinase enriched in a novel cytoskeletal fraction associated with adipocyte plasma membranes | Q40654424 | ||
| Indole-3-carbinol inhibits protein kinase B/Akt and induces apoptosis in the human breast tumor cell line MDA MB468 but not in the nontumorigenic HBL100 line. | Q40683808 | ||
| Diindolylmethane alters gene expression in human keratinocytes in vitro | Q40691533 | ||
| Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines | Q40785886 | ||
| Ligand-independent activation of estrogen receptor function by 3, 3'-diindolylmethane in human breast cancer cells | Q41737749 | ||
| Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation | Q42288805 | ||
| Cross-species comparison of angiogenesis during the premalignant stages of squamous carcinogenesis in the human cervix and K14-HPV16 transgenic mice. | Q42436858 | ||
| The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells | Q42481082 | ||
| Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indole-3-carbinol. | Q42499068 | ||
| Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane | Q42539035 | ||
| The synergistic upregulation of phase II detoxification enzymes by glucosinolate breakdown products in cruciferous vegetables. | Q43669297 | ||
| The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling | Q43848062 | ||
| Promoter methylation and silencing of PTEN in gastric carcinoma | Q43918868 | ||
| Akt inactivation is a key event in indole-3-carbinol-induced apoptosis in PC-3 cells. | Q43955737 | ||
| PTEN is a negative regulator of STAT3 activation in human papillomavirus-infected cells | Q44035401 | ||
| Demonstration and characterization of the angiogenic properties of cervical dysplasia. | Q45073729 | ||
| 3,3'-Diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic mice | Q45231913 | ||
| Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice | Q45747589 | ||
| Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling. | Q46728776 | ||
| Epigenetic and genetic alternation of PTEN in cervical neoplasm. | Q47344614 | ||
| Placebo-controlled trial of indole-3-carbinol in the treatment of CIN. | Q53407200 | ||
| PTEN/MMAC1 mutations in endometrial cancers. | Q53439663 | ||
| Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol | Q53464190 | ||
| Angiogenesis, cell proliferation and apoptosis in progression of cervical neoplasia. | Q53669873 | ||
| PTEN mutation and epidermal growth factor receptor activation regulate vascular endothelial growth factor (VEGF) mRNA expression in human glioblastoma cells by transactivating the proximal VEGF promoter. | Q55473076 | ||
| Inhibitory effects of Indole-3-carbinol on invasion and migration in human breast cancer cells | Q73243689 | ||
| Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in cervical cancer | Q73358285 | ||
| PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma | Q73374555 | ||
| Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies | Q73722520 | ||
| Angiogenesis in cervical neoplasia: microvessel quantitation in precancerous lesions and invasive carcinomas with clinicopathological correlations | Q73821893 | ||
| Angiogenesis in uterine cervical intraepithelial neoplasia and squamous cell carcinoma: an immunohistochemical study | Q74012397 | ||
| Indole-3-carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16-transgenic preneoplastic cervical epithelium | Q77340136 | ||
| Antitumour promoting activity of indole-3-carbinol in mouse skin carcinogenesis | Q77919706 | ||
| Promoter methylation of the PTEN gene is a common molecular change in breast cancer | Q80403566 | ||
| P433 | issue | 1-12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cervix uterine cancer | Q160105 |
| indole-3-carbinol | Q1770257 | ||
| P304 | page(s) | 59-63 | |
| P577 | publication date | 2005-01-01 | |
| P1433 | published in | Molecular Medicine | Q6895961 |
| P1476 | title | Indole-3-carbinol prevents PTEN loss in cervical cancer in vivo | |
| P478 | volume | 11 |
| Q37440864 | Diindolylmethane inhibits cervical dysplasia, alters estrogen metabolism, and enhances immune response in the K14-HPV16 transgenic mouse model |
| Q35521611 | Effects of DNMT1 silencing on malignant phenotype and methylated gene expression in cervical cancer cells |
| Q35190791 | Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells. |
| Q37395915 | Medical treatment of cervical intraepithelial neoplasia II, III: an update review |
| Q38342576 | Neuron membrane trafficking and protein kinases involved in autism and ADHD. |
| Q35023935 | Results from a dose-response study using 3,3'-diindolylmethane in the K14-HPV16 transgenic mouse model: cervical histology |
| Q30494717 | Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells. |
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