Factors supporting intrathecal humoral responses following viral encephalomyelitis.

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Factors supporting intrathecal humoral responses following viral encephalomyelitis. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.02260-10
P8608Fatcat IDrelease_xpjt2j72jrekvjoucffley5q2u
P932PMC publication ID3067923
P698PubMed publication ID21191015

P50authorCornelia C. BergmannQ55426323
Timothy W PharesQ117769739
Stephen A StohlmanQ117769757
P2093author name stringDavid R Hinton
Cristina P Marques
P2860cites workA macrophage mRNA selectively induced by gamma-interferon encodes a member of the platelet factor 4 family of cytokinesQ24315971
BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphomaQ24646563
Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3Q24647146
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)Q24677007
A chemokine-driven positive feedback loop organizes lymphoid folliclesQ28142202
Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivoQ28143201
BAFFled B cells survive and thrive: roles of BAFF in B-cell developmentQ28204272
A critical role for IL-21 in regulating immunoglobulin productionQ28215868
APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cellsQ28263864
Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiationQ28270256
Functional implication of BAFF synthesis and release in gangliosides-stimulated microgliaQ28581828
BCMA is essential for the survival of long-lived bone marrow plasma cellsQ28587037
The many roles of chemokines and chemokine receptors in inflammationQ29618880
Laser-capture microdissection of plasma cells from subacute sclerosing panencephalitis brain reveals intrathecal disease-relevant antibodiesQ30851947
Crucial role for BAFF-BAFF-R signaling in the survival and maintenance of mature B cellsQ33440567
RNase L mediated protection from virus induced demyelinationQ33508237
The production of antibody by invading B cells is required for the clearance of rabies virus from the central nervous system.Q33508816
Epstein-Barr virus latent infection and BAFF expression in B cells in the multiple sclerosis brain: implications for viral persistence and intrathecal B-cell activationQ33599648
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanismQ33656121
IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responsesQ33656146
Role of viral persistence in retaining CD8(+) T cells within the central nervous systemQ33810508
Monocytes regulate T cell migration through the glia limitans during acute viral encephalitisQ33826812
Interleukin-6 expression and regulation in astrocytesQ33850723
Target-dependent B7-H1 regulation contributes to clearance of central nervous system infection and dampens morbidity.Q34018474
Extrafollicular antibody responsesQ34212117
Kinetics of virus-specific CD8+ -T-cell expansion and trafficking following central nervous system infectionQ34471390
A fundamental role for interleukin-21 in the generation of T follicular helper cellsQ34792475
Control of central nervous system viral persistence by neutralizing antibodyQ34859605
Traffic patterns of B cells and plasma cells.Q34982807
BAFF AND APRIL: a tutorial on B cell survivalQ34994661
Immune responses to RNA-virus infections of the CNS.Q35140815
Homing of antibody secreting cellsQ35170914
Measles virus-specific plasma cells are prominent in subacute sclerosing panencephalitis CSFQ35755470
Regulation of plasma-cell developmentQ36058417
Biochemical characterization of a gamma interferon-inducible cytokine (IP-10).Q36353962
A coordinated change in chemokine responsiveness guides plasma cell movementsQ36369352
Coronavirus infection of the central nervous system: host-virus stand-offQ36369843
Stromal niches, plasma cell differentiation and survival.Q36450001
TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological propertiesQ37178196
Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis.Q37285430
APRIL in B-cell malignancies and autoimmunityQ37367983
IL-21: an executor of B cell fateQ37388253
IL-21 and T follicular helper cellsQ37481635
BAFF: a local and systemic target in autoimmune diseasesQ37593590
Review: The chemokine receptor CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 in neuroimmunity--a tale of conflict and conundrumQ37757179
Peptidoglycan induces interleukin‐6 expression through the TLR2 receptor, JNK, c‐Jun, and AP‐1 pathways in microgliaQ39644376
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablastsQ40066472
A proliferation-inducing ligand (APRIL) is expressed by astrocytes and is increased in multiple sclerosisQ40185060
Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nitric oxide, IL-1beta, TNF-alpha and IL-6 in an in-vitro model of brain inflammationQ40891679
Antibody prevents virus reactivation within the central nervous systemQ41670143
Inverted immunodominance and impaired cytolytic function of CD8+ T cells during viral persistence in the central nervous system.Q41689082
IgG subclass responses in brain and serum in Semliki Forest virus demyelinating encephalitisQ42079051
TACI is required for efficient plasma cell differentiation in response to T-independent type 2 antigensQ43596939
Regional differences in blood-brain barrier permeability changes and inflammation in the apathogenic clearance of virus from the central nervous systemQ43684853
Intrathecal antibody production in an animal model of multiple sclerosisQ44091072
Immunoglobulins in the cerebrospinal fluid: changes during acute viral encephalitis in mice.Q44683768
Mouse hepatitis virus pathogenesis in the central nervous system is independent of IL-15 and natural killer cells.Q45419308
Interleukin-21 mRNA expression during virus infectionsQ45420919
Semliki Forest virus-induced demyelination and remyelination--involvement of B cells and anti-myelin antibodiesQ45728524
Blood brain barrier disturbance and immunoglobulin G levels in the cerebrospinal fluid of the mouse following peripheral infection with the demyelinating strain of Semliki Forest virusQ45798882
Virus titres and persistently raised white cell counts in cerebrospinal fluid in mice after peripheral infection with demyelinating Semliki Forest virusQ45799215
Recruitment kinetics and composition of antibody-secreting cells within the central nervous system following viral encephalomyelitisQ46106385
CNS viral infection diverts homing of antibody-secreting cells from lymphoid organs to the CNS.Q46275246
IFN-gamma is required for viral clearance from central nervous system oligodendrogliaQ46323621
Regulation of matrix metalloproteinase (MMP) and tissue inhibitor of matrix metalloproteinase (TIMP) genes during JHMV infection of the central nervous system.Q46622478
Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis.Q47357498
Long term intraparenchymal Ig secretion after acute viral encephalitis in miceQ48394895
Megakaryocytes constitute a functional component of a plasma cell niche in the bone marrow.Q50550577
Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.Q51027456
Dendritic cells and monocyte/macrophages that create the IL-6/APRIL-rich lymph node microenvironments where plasmablasts mature.Q51833354
Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL.Q51966554
Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals.Q52950179
Chemotactic responsiveness toward ligands for CXCR3 and CXCR4 is regulated on plasma blasts during the time course of a memory immune response.Q52956500
B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation.Q54707196
Regulation of Homeostatic Chemokine Expression and Cell Trafficking During Immune ResponsesQ57227496
BAFF is a survival and maturation factor for mouse B cellsQ74456240
The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevityQ78346721
Antibody-secreting cells in the central nervous system in an animal model of MS: Phenotype, association with disability, and in vitro production of antibodyQ81404086
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)2589-2598
P577publication date2010-12-29
P1433published inJournal of VirologyQ1251128
P1476titleFactors supporting intrathecal humoral responses following viral encephalomyelitis
P478volume85

Reverse relations

cites work (P2860)
Q40530656Activated GL7+ B cells are maintained within the inflamed CNS in the absence of follicle formation during viral encephalomyelitis.
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Q36667911Astrocyte-derived CXCL10 drives accumulation of antibody-secreting cells in the central nervous system during viral encephalomyelitis
Q35826089CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis
Q36788638CXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis
Q35077540CXCR3-dependent plasma blast migration to the central nervous system during viral encephalomyelitis
Q92712543Central Nervous System Inflammatory Aggregates in the Theiler's Virus Model of Progressive Multiple Sclerosis
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Q37228165IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis
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Q36607157Recruitment and retention of B cells in the central nervous system in response to alphavirus encephalomyelitis
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Q36117017Utility of CSF Cytokine/Chemokines as Markers of Active Intrathecal Inflammation: Comparison of Demyelinating, Anti-NMDAR and Enteroviral Encephalitis

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