Inhibitors of the aminoglycoside 6'-N-acetyltransferase type Ib [AAC(6')-Ib] identified by in silico molecular docking

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Inhibitors of the aminoglycoside 6'-N-acetyltransferase type Ib [AAC(6')-Ib] identified by in silico molecular docking is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BMCL.2013.08.016
P932PMC publication ID3821527
P698PubMed publication ID24011645
P5875ResearchGate publication ID256467623

P2093author name stringMarcelo E Tolmasky
David L Lin
Christina Adams
Tung Tran
Jamal Y Alam
Steven R Herron
P2860cites workOpen Babel: An open chemical toolboxQ21198766
Three decades of beta-lactamase inhibitorsQ24646623
Mechanistic and Structural Analysis of Aminoglycoside N -Acetyltransferase AAC(6′)-Ib and Its Bifunctional, Fluoroquinolone-Active AAC(6′)-Ib-cr Variant † ‡Q27651667
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreadingQ27860652
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibilityQ29547658
ZINC: a free tool to discover chemistry for biologyQ29615857
Comparing aminoglycoside binding sites in bacterial ribosomal RNA and aminoglycoside modifying enzymesQ30558517
High-throughput assays for promiscuous inhibitors.Q33231455
Complete nucleotide sequence of Klebsiella pneumoniae multiresistance plasmid pJHCMW1.Q34142178
Aminoglycoside modifying enzymesQ34354185
Versatility of aminoglycosides and prospects for their futureQ35176271
External guide sequences targeting the aac(6')-Ib mRNA induce inhibition of amikacin resistanceQ35840844
Inhibition of Aminoglycoside 6′- N -Acetyltransferase Type Ib-Mediated Amikacin Resistance by Antisense OligodeoxynucleotidesQ36048468
Identification and characterization of inhibitors of the aminoglycoside resistance acetyltransferase Eis from Mycobacterium tuberculosisQ36107474
Aminoglycoside multiacetylating activity of the enhanced intracellular survival protein from Mycobacterium smegmatis and its inhibitionQ36185972
Rise and dissemination of aminoglycoside resistance: the aac(6')-Ib paradigmQ36850490
The changing face of Klebsiella pneumoniae infections in the communityQ36918418
Automated docking with protein flexibility in the design of femtomolar "click chemistry" inhibitors of acetylcholinesteraseQ36974755
Inhibition of aac(6')-Ib-mediated amikacin resistance by nuclease-resistant external guide sequences in bacteriaQ37304179
Salmonella enterica serovar Typhimurium bla(PER-1)-carrying plasmid pSTI1 encodes an extended-spectrum aminoglycoside 6'-N-acetyltransferase of type Ib.Q39740503
Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferaseQ46862305
Broad-spectrum peptide inhibitors of aminoglycoside antibiotic resistance enzymes.Q52021317
Docking of novel reversible monoamine oxidase-B inhibitors: efficient prediction of ligand binding sites and estimation of inhibitors thermodynamic propertiesQ57013065
NMR-guided fragment-based approach for the design of AAC(6')-Ib ligandsQ81235414
P433issue20
P407language of work or nameEnglishQ1860
P921main subjectin silicoQ192572
P304page(s)5694-5698
P577publication date2013-08-12
P1433published inBioorganic & Medicinal Chemistry LettersQ2709483
P1476titleInhibitors of the aminoglycoside 6'-N-acetyltransferase type Ib [AAC(6')-Ib] identified by in silico molecular docking
P478volume23

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cites work (P2860)
Q52744431Amikacin: Uses, Resistance, and Prospects for Inhibition.
Q48317932Comprehensive review of chemical strategies for the preparation of new aminoglycosides and their biological activities
Q38653386Effect of solvent and protein dynamics in ligand recognition and inhibition of aminoglycoside adenyltransferase 2″-Ia
Q48509625Identification of a small molecule inhibitor of the aminoglycoside 6'-N-acetyltransferase type ib [AAC(6')-ib] using mixture-based combinatorial libraries
Q35955677Identification of an Inhibitor of the Aminoglycoside 6'-N-Acetyltransferase type Ib [AAC(6')-Ib] by Glide Molecular Docking
Q33798534Inhibition of aminoglycoside 6'-N-acetyltransferase type Ib by zinc: reversal of amikacin resistance in Acinetobacter baumannii and Escherichia coli by a zinc ionophore
Q35960865Inhibition of aminoglycoside 6'-N-acetyltransferase type Ib-mediated amikacin resistance in Klebsiella pneumoniae by zinc and copper pyrithione
Q35746230Inhibition of aminoglycoside acetyltransferase resistance enzymes by metal salts
Q90192897Multitarget Approaches against Multiresistant Superbugs
Q36281015Synthesis and Biological Activity of Mono- and Di-N-acylated Aminoglycosides

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