scholarly article | Q13442814 |
P50 | author | John S Blanchard | Q89141307 |
George A Jacoby | Q104979117 | ||
P2093 | author name string | Matthew W Vetting | |
Subray S Hegde | |||
David C Hooper | |||
Chi Hye Park | |||
P2860 | cites work | Investigation of the roles of catalytic residues in serotonin N-acetyltransferase | Q27638256 |
Enzyme structural plasticity and the emergence of broad-spectrum antibiotic resistance | Q27649912 | ||
Coot: model-building tools for molecular graphics | Q27860505 | ||
PRODRG: a tool for high-throughput crystallography of protein-ligand complexes | Q27860633 | ||
wARP: improvement and extension of crystallographic phases by weighted averaging of multiple-refined dummy atomic models | Q27860981 | ||
Refinement of macromolecular structures by the maximum-likelihood method | Q27861011 | ||
Scaling and assessment of data quality | Q27861107 | ||
The integration of macromolecular diffraction data | Q27861123 | ||
Structure and functions of the GNAT superfamily of acetyltransferases | Q28296840 | ||
Overexpression and mechanistic analysis of chromosomally encoded aminoglycoside 2'-N-acetyltransferase (AAC(2')-Ic) from Mycobacterium tuberculosis | Q28486391 | ||
Recent developments in the PHENIX software for automated crystallographic structure determination | Q29620754 | ||
Aminoglycoside-modifying enzymes | Q33745231 | ||
Mutagenesis analysis of a conserved region involved in acetyl coenzyme A binding in the aminoglycoside 6'-N-acetyltransferase type Ib encoded by plasmid pJHCMW1. | Q33883705 | ||
Systematic analysis of a conserved region of the aminoglycoside 6'-N-acetyltransferase type Ib. | Q33983481 | ||
Molecular characterization of a novel class 1 integron containing bla(GES-1) and a fused product of aac3-Ib/aac6'-Ib' gene cassettes in Pseudomonas aeruginosa | Q34113541 | ||
Mechanisms of action of antimicrobials: focus on fluoroquinolones | Q34183520 | ||
The worldwide emergence of plasmid-mediated quinolone resistance | Q34569740 | ||
Mechanisms of resistance to quinolones: target alterations, decreased accumulation and DNA gyrase protection. | Q35107937 | ||
Versatility of aminoglycosides and prospects for their future | Q35176271 | ||
Molecular cloning of amikacin resistance determinants from a Klebsiella pneumoniae plasmid | Q35651704 | ||
Molecular insights into aminoglycoside action and resistance | Q36034615 | ||
Quinolone resistance in bacteria: emphasis on plasmid-mediated mechanisms | Q36125234 | ||
Efflux-mediated antimicrobial resistance | Q36138147 | ||
Mechanisms of resistance to quinolones | Q36155441 | ||
Emerging plasmid-mediated quinolone resistance associated with the qnr gene in Klebsiella pneumoniae clinical isolates in the United States | Q37121208 | ||
Mechanistic characterization of the bifunctional aminoglycoside-modifying enzyme AAC(3)-Ib/AAC(6')-Ib' from Pseudomonas aeruginosa | Q38302896 | ||
Genetic analysis of bacterial acetyltransferases: identification of amino acids determining the specificities of the aminoglycoside 6'-N-acetyltransferase Ib and IIa proteins | Q38328977 | ||
The molecular basis of the expansive substrate specificity of the antibiotic resistance enzyme aminoglycoside acetyltransferase-6'-aminoglycoside phosphotransferase-2". The role of ASP-99 as an active site base important for acetyl transfer | Q38358019 | ||
The changing nature of aminoglycoside resistance mechanisms and the role of isepamicin--a new broad-spectrum aminoglycoside. The Aminoglycoside Resistance Study Groups. | Q38563911 | ||
Prodigious substrate specificity of AAC(6')-APH(2"), an aminoglycoside antibiotic resistance determinant in enterococci and staphylococci | Q40824066 | ||
The kinetic mechanism of AAC3-IV aminoglycoside acetyltransferase from Escherichia coli | Q41331869 | ||
Bacterial resistance to aminoglycoside antibiotics | Q41522159 | ||
Kinetic and mutagenic characterization of the chromosomally encoded Salmonella enterica AAC(6')-Iy aminoglycoside N-acetyltransferase | Q43571417 | ||
Kinetic mechanisms of gentamicin acetyltransferase I. Antibiotic-dependent shift from rapid to nonrapid equilibrium random mechanisms | Q43888930 | ||
Kinetic mechanism of the GCN5-related chromosomal aminoglycoside acetyltransferase AAC(6')-Ii from Enterococcus faecium: evidence of dimer subunit cooperativity | Q44454184 | ||
Molecular mechanism of the enterococcal aminoglycoside 6'-N-acetyltransferase': role of GNAT-conserved residues in the chemistry of antibiotic inactivation | Q44724468 | ||
Characterization of the bifunctional aminoglycoside-modifying enzyme ANT(3'')-Ii/AAC(6')-IId from Serratia marcescens | Q46337932 | ||
Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase | Q46862305 | ||
Kinetic studies of aminoglycoside acetyltransferase and phosphotransferase from Staphylococcus aureus RPAL. Relationship between the two activities. | Q54495323 | ||
The use of pH studies to determine chemical mechanisms of enzyme-catalyzed reactions | Q70610443 | ||
Mechanisms of fluoroquinolone resistance | Q74371163 | ||
Studies on kanamycin | Q74819952 | ||
A resin chromatographic analysis for kanamycin mixtures | Q78585773 | ||
P433 | issue | 37 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 9825-35 | |
P577 | publication date | 2008-09-16 | |
P1433 | published in | Biochemistry | Q764876 |
P1476 | title | Mechanistic and Structural Analysis of Aminoglycoside N -Acetyltransferase AAC(6′)-Ib and Its Bifunctional, Fluoroquinolone-Active AAC(6′)-Ib-cr Variant † ‡ | |
P478 | volume | 47 |
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