Amikacin: Uses, Resistance, and Prospects for Inhibition.

scientific article published on 19 December 2017

Amikacin: Uses, Resistance, and Prospects for Inhibition. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3390/MOLECULES22122267
P932PMC publication ID5889950
P698PubMed publication ID29257114

P2093author name stringMarcelo E Tolmasky
Maria S Ramirez
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Complete nucleotide sequence of Klebsiella pneumoniae multiresistance plasmid pJHCMW1.Q34142178
Vestibular and cochlear toxicity of aminoglycosides--a reviewQ34152908
Neomycin and Paromomycin Inhibit 30S Ribosomal Subunit Assembly in Staphylococcus aureusQ34271422
Identification of a novel 6'-N-aminoglycoside acetyltransferase, AAC(6')-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophiliaQ34298833
Structure of the bifunctional aminoglycoside-resistance enzyme AAC(6')-Ie-APH(2'')-Ia revealed by crystallographic and small-angle X-ray scattering analysisQ34299292
Liposome-encapsulated aminoglycosides in pre-clinical and clinical studiesQ34353844
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In vitro activity of plazomicin against β-lactamase-producing carbapenem-resistant Enterobacteriaceae (CRE).Q52841787
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External guide sequence technology: a path to development of novel antimicrobial therapeuticsQ36143151
Combination therapy for treatment of infections with gram-negative bacteriaQ36156077
Optimizing the initial amikacin dosage in adultsQ36158283
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Sequencing and expression of the 6'-N-acetyltransferase gene of transposon Tn1331 from Klebsiella pneumoniaeQ36212292
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NMR-guided fragment-based approach for the design of AAC(6')-Ib ligandsQ81235414
Aminoglycoside-induced ototoxicityQ85318201
Mycobacterium tuberculosis rrs A1401G mutation correlates with high-level resistance to kanamycin, amikacin, and capreomycin in clinical isolates from mainland ChinaQ87260032
Assessment of configurations and chemistries of bridged nucleic acids-containing oligomers as external guide sequences: a methodology for inhibition of expression of antibiotic resistance genesQ88786417
Intrathecal or intraventricular administration of colistin, vancomycin and amikacin for central nervous system infections in neurosurgical patients in an intensive care unitQ89209050
Complete nucleotide sequence of cfr-carrying IncX4 plasmid pSD11 from Escherichia coliQ34923330
Inhibitors of the aminoglycoside 6'-N-acetyltransferase type Ib [AAC(6')-Ib] identified by in silico molecular dockingQ34980567
Singly modified amikacin and tobramycin derivatives show increased rRNA A-site binding and higher potency against resistant bacteriaQ34982853
Effects of Membrane-Energy Mutations and Cations on Streptomycin and Gentamicin Accumulation by Bacteria: a Model for Entry of Streptomycin and Gentamicin in Susceptible and Resistant BacteriaQ34984041
Mechanisms of antibiotic resistanceQ35053439
Plasmid-Mediated Antibiotic Resistance and Virulence in Gram-negatives: the Klebsiella pneumoniae ParadigmQ35104348
Versatility of aminoglycosides and prospects for their futureQ35176271
Quantification of amikacin in bronchial epithelial lining fluid in neonates.Q35191478
Draft Genome of the Multidrug-Resistant Acinetobacter baumannii Strain A155 Clinical IsolateQ35255727
Mobility of gentamicin resistance genes from staphylococci isolated in the United States: identification of Tn4031, a gentamicin resistance transposon from Staphylococcus epidermidisQ35344263
Characterization of Tn6238 with a new allele of aac(6')-Ib-crQ35385866
Tn1331, a novel multiresistance transposon encoding resistance to amikacin and ampicillin in Klebsiella pneumoniaeQ35562903
High-level amikacin resistance in Escherichia coli due to phosphorylation and impaired aminoglycoside uptakeQ35573156
Plasmid-encoded amikacin resistance in multiresistant strains of Klebsiella pneumoniae isolated from neonates with meningitisQ35573551
Structure-activity relationships for antibacterial to antifungal conversion of kanamycin to amphiphilic analogues.Q35590862
Sublethal concentrations of the aminoglycoside amikacin interfere with cell division without affecting chromosome dynamicsQ35635646
Molecular cloning of amikacin resistance determinants from a Klebsiella pneumoniae plasmidQ35651704
Properties of an R plasmid in Pseudomonas aeruginosa producing amikacin (BB-K8), butirosin, kanamycin, tobramycin, and sisomicin resistanceQ35660594
New plasmid-mediated aminoglycoside adenylyltransferase of broad substrate range that adenylylates amikacinQ35670920
Inhibition of aminoglycoside acetyltransferase resistance enzymes by metal saltsQ35746230
Insertion Sequence IS26 Reorganizes Plasmids in Clinically Isolated Multidrug-Resistant Bacteria by Replicative TranspositionQ35753670
Characterization of the chromosomal aac(6')-Ii gene specific for Enterococcus faeciumQ35819363
External guide sequences targeting the aac(6')-Ib mRNA induce inhibition of amikacin resistanceQ35840844
Amphiphilic Tobramycin Analogues as Antibacterial and Antifungal AgentsQ35859918
Increased resistance to amikacin in a neonatal unit following intensive amikacin usageQ35893360
Identification of an Inhibitor of the Aminoglycoside 6'-N-Acetyltransferase type Ib [AAC(6')-Ib] by Glide Molecular DockingQ35955677
Inhibition of AAC(6')-Ib-mediated resistance to amikacin in Acinetobacter baumannii by an antisense peptide-conjugated 2',4'-bridged nucleic acid-NC-DNA hybrid oligomerQ35960810
Inhibition of aminoglycoside 6'-N-acetyltransferase type Ib-mediated amikacin resistance in Klebsiella pneumoniae by zinc and copper pyrithioneQ35960865
Molecular insights into aminoglycoside action and resistanceQ36034615
Inhibition of Aminoglycoside 6′- N -Acetyltransferase Type Ib-Mediated Amikacin Resistance by Antisense OligodeoxynucleotidesQ36048468
Identification and characterization of inhibitors of the aminoglycoside resistance acetyltransferase Eis from Mycobacterium tuberculosisQ36107474
Activity of plazomicin (ACHN-490) against MDR clinical isolates of Klebsiella pneumoniae, Escherichia coli, and Enterobacter spp. from Athens, GreeceQ36107990
Molecular targets for design of novel inhibitors to circumvent aminoglycoside resistanceQ36109016
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectamikacinQ408529
carbohydrateQ11358
antibioticQ12187
P577publication date2017-12-19
P1433published inMoleculesQ151332
P1476titleAmikacin: Uses, Resistance, and Prospects for Inhibition.
P478volume22

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