Type I-E CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition

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Type I-E CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1003742
P932PMC publication ID3764190
P698PubMed publication ID24039596
P5875ResearchGate publication ID256613982

P50authorEdze R WestraQ83369943
Stan J. J. BrounsQ90943178
Ryan JacksonQ43084035
P2093author name stringEkaterina Semenova
Konstantin Severinov
Blake Wiedenheft
Kirill A Datsenko
P2860cites workEvolutionary conservation of sequence and secondary structures in CRISPR repeatsQ21184123
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Cas6 is an endoribonuclease that generates guide RNAs for invader defense in prokaryotesQ27653417
Sequence- and Structure-Specific RNA Processing by a CRISPR EndonucleaseQ27664403
Structural and Functional Characterization of an Archaeal Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Complex for Antiviral Defense (CASCADE)Q27667493
Cas5d Protein Processes Pre-crRNA and Assembles into a Cascade-like Interference Complex in Subtype I-C/Dvulg CRISPR-Cas SystemQ27670930
Structure and Mechanism of the CMR Complex for CRISPR-Mediated Antiviral ImmunityQ27676627
Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune SystemQ27678641
Crystal Structure of the Largest Subunit of a Bacterial RNA-guided Immune Complex and Its Role in DNA Target BindingQ27679265
Small CRISPR RNAs guide antiviral defense in prokaryotesQ28290898
The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNAQ28297640
RNA-guided genetic silencing systems in bacteria and archaeaQ29614421
RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complexQ29615785
CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNAQ29615786
Evolution and classification of the CRISPR-Cas systemsQ29616645
Phage response to CRISPR-encoded resistance in Streptococcus thermophilusQ29617060
Structures of the RNA-guided surveillance complex from a bacterial immune systemQ30587075
Self versus non-self discrimination during CRISPR RNA-directed immunity.Q33620668
Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systemsQ33960829
The rise and fall of CRISPRs – dynamics of spacer acquisition and lossQ50946708
Csy4 is responsible for CRISPR RNA processing in Pectobacterium atrosepticumQ52422407
Bacteriophage resistance mechanismsQ34021879
CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulationQ34068759
Identification and characterization of E. coli CRISPR-cas promoters and their silencing by H-NS.Q34096920
Dynamic properties of the Sulfolobus CRISPR/Cas and CRISPR/Cmr systems when challenged with vector-borne viral and plasmid genes and protospacersQ34155448
In vivo activity of CRISPR-mediated virus defence in a hyperthermophilic archaeonQ34169232
Structural basis for CRISPR RNA-guided DNA recognition by CascadeQ34175461
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequenceQ34190309
Mature clustered, regularly interspaced, short palindromic repeats RNA (crRNA) length is measured by a ruler mechanism anchored at the precursor processing siteQ34240056
Essential features and rational design of CRISPR RNAs that function with the Cas RAMP module complex to cleave RNAs.Q34245546
CRISPR interference directs strand specific spacer acquisitionQ34256881
Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coliQ34259727
Experimental definition of a clustered regularly interspaced short palindromic duplicon in Escherichia coliQ34286625
Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity systemQ34287113
Selective and hyperactive uptake of foreign DNA by adaptive immune systems of an archaeon via two distinct mechanisms.Q34290429
Function and regulation of clustered regularly interspaced short palindromic repeats (CRISPR) / CRISPR associated (Cas) systems.Q34314875
Cleavage of phage DNA by the Streptococcus thermophilus CRISPR3-Cas systemQ34387539
Target motifs affecting natural immunity by a constitutive CRISPR-Cas system in Escherichia coli.Q34494161
Mobile CRISPR/Cas-mediated bacteriophage resistance in Lactococcus lactisQ34512535
Self-targeting by CRISPR: gene regulation or autoimmunity?Q34621188
The CRISPRs, they are a-changin': how prokaryotes generate adaptive immunityQ34645309
Cytotoxic chromosomal targeting by CRISPR/Cas systems can reshape bacterial genomes and expel or remodel pathogenicity islandsQ34699789
Prokaryotic silencing (psi)RNAs in Pyrococcus furiosusQ34868607
Short motif sequences determine the targets of the prokaryotic CRISPR defence systemQ34953078
RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactionsQ35064344
An Archaeal Immune System Can Detect Multiple Protospacer Adjacent Motifs (PAMs) to Target Invader DNAQ36286108
Cas5d processes pre-crRNA and is a member of a larger family of CRISPR RNA endonucleasesQ36342243
Innate and adaptive immunity in bacteria: mechanisms of programmed genetic variation to fight bacteriophagesQ37955485
H-NS-mediated repression of CRISPR-based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO.Q38342191
The CRISPR/Cas adaptive immune system of Pseudomonas aeruginosa mediates resistance to naturally occurring and engineered phagesQ41584259
Transcription, processing and function of CRISPR cassettes in Escherichia coliQ41950756
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3Q42128481
In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus.Q42262732
The Escherichia coli CRISPR system protects from λ lysogenization, lysogens, and prophage inductionQ42363720
The highly dynamic CRISPR1 system of Streptococcus agalactiae controls the diversity of its mobilome.Q46482246
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P921main subjectCRISPRQ412563
P304page(s)e1003742
P577publication date2013-09-05
P1433published inPLOS GeneticsQ1893441
P1476titleType I-E CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition
P478volume9

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