scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | Michael P Terns | |
Rebecca M Terns | |||
P2860 | cites work | A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes | Q21090166 |
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CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes | Q21508827 | ||
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Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated genome defense | Q27655927 | ||
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A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair | Q27666531 | ||
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Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements | Q29615788 | ||
Identification of genes that are associated with DNA repeats in prokaryotes | Q29615790 | ||
Evolution and classification of the CRISPR-Cas systems | Q29616645 | ||
Phage response to CRISPR-encoded resistance in Streptococcus thermophilus | Q29617060 | ||
Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin | Q29617073 | ||
CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea | Q29617488 | ||
Identification of novel non-coding RNAs as potential antisense regulators in the archaeon Sulfolobus solfataricus | Q31142371 | ||
Self versus non-self discrimination during CRISPR RNA-directed immunity. | Q33620668 | ||
CRISPR associated diversity within a population of Sulfolobus islandicus | Q33712112 | ||
Evolutionary dynamics of clustered irregularly interspaced short palindromic repeat systems in the ocean metagenome. | Q33768265 | ||
CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies. | Q33985645 | ||
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CRISPI: a CRISPR interactive database | Q34019852 | ||
Analysis of streptococcal CRISPRs from human saliva reveals substantial sequence diversity within and between subjects over time. | Q34024986 | ||
The CRISPR system: small RNA-guided defense in bacteria and archaea | Q34096589 | ||
CRISPR/Cas system and its role in phage-bacteria interactions | Q34119422 | ||
Dynamic properties of the Sulfolobus CRISPR/Cas and CRISPR/Cmr systems when challenged with vector-borne viral and plasmid genes and protospacers | Q34155448 | ||
In vivo activity of CRISPR-mediated virus defence in a hyperthermophilic archaeon | Q34169232 | ||
Binding and cleavage of CRISPR RNA by Cas6 | Q34210424 | ||
Self-targeting by CRISPR: gene regulation or autoimmunity? | Q34621188 | ||
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Virus population dynamics and acquired virus resistance in natural microbial communities | Q34780702 | ||
Prokaryotic silencing (psi)RNAs in Pyrococcus furiosus | Q34868607 | ||
Distribution of CRISPR spacer matches in viruses and plasmids of crenarchaeal acidothermophiles and implications for their inhibitory mechanism. | Q34921482 | ||
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Comparative analysis of CRISPR loci in lactic acid bacteria genomes. | Q52422277 | ||
Viral biogeography revealed by signatures in Sulfolobus islandicus genomes. | Q52422288 | ||
CRISPR elements in the Thermococcales: evidence for associated horizontal gene transfer in Pyrococcus furiosus. | Q52422303 | ||
Transcription profile of Thermus thermophilus CRISPR systems after phage infection. | Q52422306 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | CRISPR | Q412563 |
P304 | page(s) | 321-7 | |
P577 | publication date | 2011-06-01 | |
P1433 | published in | Current Opinion in Microbiology | Q15752444 |
P1476 | title | CRISPR-based adaptive immune systems | |
P478 | volume | 14 |
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Q92378292 | A Practical Guide to Genome Editing Using Targeted Nuclease Technologies |
Q24669850 | A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity |
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Q52430518 | A detailed cell-free transcription-translation-based assay to decipher CRISPR protospacer-adjacent motifs. |
Q33850539 | A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression |
Q35853457 | A genome-wide view of the expression and processing patterns of Thermus thermophilus HB8 CRISPR RNAs |
Q34322670 | A novel interference mechanism by a type IIIB CRISPR-Cmr module in Sulfolobus. |
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Q42210686 | Adaptation and modification of three CRISPR loci in two closely related cyanobacteria |
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Q36286108 | An archaeal immune system can detect multiple protospacer adjacent motifs (PAMs) to target invader DNA. |
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Q35482661 | Archaeal extrachromosomal genetic elements |
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Q41632288 | BREX is a novel phage resistance system widespread in microbial genomes. |
Q28657639 | Bacterial genome instability |
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Q39003630 | Biological applications of xeno nucleic acids. |
Q21131779 | CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool |
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Q42148640 | CRISPR adaptation biases explain preference for acquisition of foreign DNA |
Q42544844 | CRISPR decoys: competitive inhibitors of CRISPR immunity |
Q38196778 | CRISPR-Cas system: a powerful tool for genome engineering |
Q27015486 | CRISPR-Cas systems and RNA-guided interference |
Q21133677 | CRISPR-Cas systems in the cyanobacterium Synechocystis sp. PCC6803 exhibit distinct processing pathways involving at least two Cas6 and a Cmr2 protein |
Q39097200 | CRISPR-Cas type I-A Cascade complex couples viral infection surveillance to host transcriptional regulation in the dependence of Csa3b |
Q64937079 | CRISPR-Cas9 Mediated Genome Editing in Bicyclus anynana Butterflies. |
Q34405661 | CRISPR-based technologies: prokaryotic defense weapons repurposed |
Q35202364 | CRISPR-induced distributed immunity in microbial populations. |
Q98465771 | CRISPR/Cas9 Gene Editing: An Unexplored Frontier for Forest Pathology |
Q38225327 | CRISPR/Cas9-Directed Genome Editing of Cultured Cells |
Q91885985 | CRISPR/Cas9-based epigenome editing: An overview of dCas9-based tools with special emphasis on off-target activity |
Q39254615 | CRISPR/Cas9: An RNA-guided highly precise synthetic tool for plant genome editing |
Q26748192 | CRISPR/Cas9: a breakthrough in generating mouse models for endocrinologists |
Q37079810 | CRISPRTarget: bioinformatic prediction and analysis of crRNA targets. |
Q28679191 | CRISPRmap: an automated classification of repeat conservation in prokaryotic adaptive immune systems |
Q39298283 | Cas6 processes tight and relaxed repeat RNA via multiple mechanisms: A hypothesis |
Q24564294 | Cas9 as a versatile tool for engineering biology |
Q35104144 | Cas9 function and host genome sampling in Type II-A CRISPR-Cas adaptation |
Q38041299 | Cascade-mediated binding and bending of negatively supercoiled DNA. |
Q45072574 | Challenges and Advances for Genetic Engineering of Non-model Bacteria and Uses in Consolidated Bioprocessing |
Q41995245 | Characterization of CRISPR RNA processing in Clostridium thermocellum and Methanococcus maripaludis |
Q35943228 | Characterization of the CRISPR/Cas subtype I-A system of the hyperthermophilic crenarchaeon Thermoproteus tenax |
Q45874360 | Combining Engineered Nucleases with Adeno-associated Viral Vectors for Therapeutic Gene Editing |
Q49852205 | Comparative Analysis of Lipid-Mediated CRISPR-Cas9 Genome Editing Techniques |
Q41840786 | Comparative analysis ofCas6b processing and CRISPR RNA stability. |
Q21266706 | Comparative genomic analysis of Geobacter sulfurreducens KN400, a strain with enhanced capacity for extracellular electron transfer and electricity production |
Q36757203 | Comparative genomic analysis of phylogenetically closely related Hydrogenobaculum sp. isolates from Yellowstone National Park |
Q34519053 | Conditional Control of CRISPR/Cas9 Function. |
Q38855096 | Construction of a CRISPR-Cas9 System for Pig Genome Targeting |
Q37277585 | Control of gene expression by CRISPR-Cas systems |
Q27681727 | Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA |
Q27682287 | Crystal structure and nucleic acid-binding activity of the CRISPR-associated protein Csx1 of Pyrococcus furiosus |
Q27678215 | Crystal structure of Cmr2 suggests a nucleotide cyclase-related enzyme in type III CRISPR-Cas systems |
Q36191874 | Crystal structures of CRISPR-associated Csx3 reveal a manganese-dependent deadenylation exoribonuclease. |
Q35705114 | Crystallization and preliminary X-ray diffraction analysis of the CRISPR-Cas RNA-silencing Cmr complex |
Q36865378 | Crystallization and preliminary X-ray diffraction analysis of the Cmr2-Cmr3 subcomplex in the CRISPR-Cas RNA-silencing effector complex |
Q27678649 | Csy4 relies on an unusual catalytic dyad to position and cleave CRISPR RNA |
Q48023223 | Curbing Malaria: A New Hope through Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Technology |
Q36337685 | DNA targeting by the type I-G and type I-A CRISPR-Cas systems of Pyrococcus furiosus. |
Q34038379 | Dealing with the evolutionary downside of CRISPR immunity: bacteria and beneficial plasmids |
Q89634987 | Deep learning improves the ability of sgRNA off-target propensity prediction |
Q35142271 | Degenerate target sites mediate rapid primed CRISPR adaptation. |
Q45863203 | Deletion of the GAA repeats from the human frataxin gene using the CRISPR-Cas9 system in YG8R-derived cells and mouse models of Friedreich ataxia |
Q37035274 | Different Effects of sgRNA Length on CRISPR-mediated Gene Knockout Efficiency |
Q97519222 | Diphtheria toxin-mediated transposon-driven poly (A)-trapping efficiently disrupts transcriptionally silent genes in embryonic stem cells |
Q39194990 | Disease modeling in genetic kidney diseases: zebrafish |
Q34536517 | Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems |
Q37271124 | Efficient generation of large-scale genome-modified mice using gRNA and CAS9 endonuclease |
Q24610828 | Efficient genome editing in zebrafish using a CRISPR-Cas system |
Q37117695 | Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system |
Q38126465 | Engineering subtle targeted mutations into the mouse genome |
Q34245546 | Essential features and rational design of CRISPR RNAs that function with the Cas RAMP module complex to cleave RNAs. |
Q34724892 | Essential structural and functional roles of the Cmr4 subunit in RNA cleavage by the Cmr CRISPR-Cas complex |
Q37694875 | Establishment of mitochondrial pyruvate carrier 1 (MPC1) gene knockout mice with preliminary gene function analyses |
Q27680426 | Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases |
Q92994222 | Evolution of CRISPR towards accurate and efficient mammal genome engineering |
Q34314875 | Function and regulation of clustered regularly interspaced short palindromic repeats (CRISPR) / CRISPR associated (Cas) systems. |
Q56809227 | Functions and Applications of RNA-Guided CRISPR-Cas Immune Systems |
Q39228160 | Gene editing as applied to prevention of reproductive porcine reproductive and respiratory syndrome |
Q43179830 | Generation of gene-modified mice via Cas9/RNA-mediated gene targeting |
Q34657143 | Genetic characterization of antiplasmid immunity through a type III-A CRISPR-Cas system |
Q41968713 | Genetic determinants of PAM-dependent DNA targeting and pre-crRNA processing in Sulfolobus islandicus. |
Q50633917 | Genome editing in rice and wheat using the CRISPR/Cas system |
Q94572519 | Genome editing in the nematode Caenorhabditis briggsae using the CRISPR/Cas9 system |
Q34093413 | Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells |
Q34582389 | Genomic reconstruction of transcriptional regulatory networks in lactic acid bacteria. |
Q52422434 | Helicase dissociation and annealing of RNA-DNA hybrids by Escherichia coli Cas3 protein. |
Q34850698 | Heritable and precise zebrafish genome editing using a CRISPR-Cas system |
Q37269749 | Heritable custom genomic modifications in Caenorhabditis elegans via a CRISPR-Cas9 system |
Q24601099 | Heritable genome editing in C. elegans via a CRISPR-Cas9 system |
Q36067284 | High quality draft genome sequence of Corynebacterium ulceribovis type strain IMMIB-L1395(T) (DSM 45146(T)) |
Q46235696 | High-Throughput Characterization of Cascade type I-E CRISPR Guide Efficacy Reveals Unexpected PAM Diversity and Target Sequence Preferences |
Q29616045 | High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells |
Q42207944 | Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes |
Q35943573 | Identification of novel positive-strand RNA viruses by metagenomic analysis of archaea-dominated Yellowstone hot springs |
Q27681687 | Identification, structural, and biochemical characterization of a group of large Csn2 proteins involved in CRISPR-mediated bacterial immunity |
Q38825672 | Imaging Specific Genomic DNA in Living Cells |
Q38192180 | Impact of CRISPR immunity on the emergence and virulence of bacterial pathogens |
Q35253340 | Impact of small repeat sequences on bacterial genome evolution. |
Q42262732 | In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus. |
Q41079017 | IncH-type plasmid harboring bla CTX-M-15, bla DHA-1, and qnrB4 genes recovered from animal isolates |
Q42242892 | Inter-viral conflicts that exploit host CRISPR immune systems of Sulfolobus |
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Q38057517 | Memory of viral infections by CRISPR-Cas adaptive immune systems: acquisition of new information |
Q41820341 | Microevolution in cyanobacteria: re-sequencing a motile substrain of Synechocystis sp. PCC 6803. |
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Q41866629 | Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia |
Q34352087 | Performance of the Cas9 nickase system in Drosophila melanogaster |
Q37194743 | Precise and heritable genome editing in evolutionarily diverse nematodes using TALENs and CRISPR/Cas9 to engineer insertions and deletions |
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Q42092486 | Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer. |
Q36959817 | Processing-independent CRISPR RNAs limit natural transformation in Neisseria meningitidis |
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Q24632944 | Protospacer recognition motifs: mixed identities and functional diversity |
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Q34032842 | RNA processing in the minimal organism Nanoarchaeum equitans |
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Q27676664 | Recognition and Cleavage of a Nonstructured CRISPR RNA by Its Processing Endoribonuclease Cas6 |
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Q35089011 | Sequences spanning the leader-repeat junction mediate CRISPR adaptation to phage in Streptococcus thermophilus |
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Q41123896 | Solution properties of the archaeal CRISPR DNA repeat-binding homeodomain protein Cbp2. |
Q45976671 | Strong bias in the bacterial CRISPR elements that confer immunity to phage. |
Q34860823 | Structural Principles of CRISPR RNA Processing |
Q28818412 | Structure Principles of CRISPR-Cas Surveillance and Effector Complexes |
Q37394423 | Structure of an RNA silencing complex of the CRISPR-Cas immune system. |
Q27677966 | Structure of the Cmr2 Subunit of the CRISPR-Cas RNA Silencing Complex |
Q27676268 | Structure of the Cmr2-Cmr3 Subcomplex of the Cmr RNA Silencing Complex |
Q34433997 | Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation |
Q27681624 | Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation |
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Q34430749 | Target RNA capture and cleavage by the Cmr type III-B CRISPR-Cas effector complex |
Q35114320 | Target specificity of the CRISPR-Cas9 system. |
Q92129016 | Target-dependent nickase activities of the CRISPR-Cas nucleases Cpf1 and Cas9 |
Q34257396 | Targeted mutagenesis in Atlantic salmon (Salmo salar L.) using the CRISPR/Cas9 system induces complete knockout individuals in the F0 generation |
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