| scholarly article | Q13442814 |
| P50 | author | Emmanuelle Charpentier | Q17280087 |
| Anaïs Le Rhun | Q56486786 | ||
| Krzysztof Chylinski | Q56517631 | ||
| P2860 | cites work | A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes | Q21090166 |
| Evolutionary conservation of sequence and secondary structures in CRISPR repeats | Q21184123 | ||
| A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action | Q21203780 | ||
| RNAalifold: improved consensus structure prediction for RNA alignments | Q21284196 | ||
| The CRISPRdb database and tools to display CRISPRs and to generate dictionaries of spacers and repeats | Q21284230 | ||
| MUSCLE: a multiple sequence alignment method with reduced time and space complexity | Q21284290 | ||
| CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes | Q21508827 | ||
| The HHpred interactive server for protein homology detection and structure prediction | Q24530456 | ||
| Gapped BLAST and PSI-BLAST: a new generation of protein database search programs | Q24545170 | ||
| Regulatory RNAs in bacteria | Q24595082 | ||
| CRISPR-based adaptive immune systems | Q24609425 | ||
| CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III | Q24628207 | ||
| A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity | Q24669850 | ||
| Regulation by small RNAs in bacteria: expanding frontiers | Q27009044 | ||
| Ultrafast evolution and loss of CRISPRs following a host shift in a novel wildlife pathogen, Mycoplasma gallisepticum | Q27334811 | ||
| Cas6 is an endoribonuclease that generates guide RNAs for invader defense in prokaryotes | Q27653417 | ||
| Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated genome defense | Q27655927 | ||
| Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease | Q27664403 | ||
| Interaction of the Cas6 Riboendonuclease with CRISPR RNAs: Recognition and Cleavage | Q27666877 | ||
| Structural and Functional Characterization of an Archaeal Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Complex for Antiviral Defense (CASCADE) | Q27667493 | ||
| An RNA-induced conformational change required for CRISPR RNA cleavage by the endoribonuclease Cse3 | Q27667849 | ||
| Recognition and maturation of effector RNAs in a CRISPR interference pathway | Q27667851 | ||
| Structural and Biochemical Analysis of Nuclease Domain of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Protein 3 (Cas3) | Q27670901 | ||
| Cas5d Protein Processes Pre-crRNA and Assembles into a Cascade-like Interference Complex in Subtype I-C/Dvulg CRISPR-Cas System | Q27670930 | ||
| Structure and Mechanism of the CMR Complex for CRISPR-Mediated Antiviral Immunity | Q27676627 | ||
| Crystal Structure of Streptococcus pyogenes Csn2 Reveals Calcium-Dependent Conformational Changes in Its Tertiary and Quaternary Structure | Q27678337 | ||
| Identification, structural, and biochemical characterization of a group of large Csn2 proteins involved in CRISPR‐mediated bacterial immunity | Q27681687 | ||
| The Sequence Alignment/Map format and SAMtools | Q27860966 | ||
| Secondary structure prediction for aligned RNA sequences | Q28206303 | ||
| Small CRISPR RNAs guide antiviral defense in prokaryotes | Q28290898 | ||
| The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA | Q28297640 | ||
| FastTree 2--approximately maximum-likelihood trees for large alignments | Q28748616 | ||
| BEDTools: a flexible suite of utilities for comparing genomic features | Q29547332 | ||
| Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria | Q29614420 | ||
| RNA-guided genetic silencing systems in bacteria and archaea | Q29614421 | ||
| CRISPR/Cas, the immune system of bacteria and archaea | Q29614423 | ||
| CRISPR--a widespread system that provides acquired resistance against phages in bacteria and archaea | Q29614740 | ||
| RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex | Q29615785 | ||
| CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA | Q29615786 | ||
| Identification of genes that are associated with DNA repeats in prokaryotes | Q29615790 | ||
| Evolution and classification of the CRISPR-Cas systems | Q29616645 | ||
| Phage response to CRISPR-encoded resistance in Streptococcus thermophilus | Q29617060 | ||
| CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea | Q29617488 | ||
| Structures of the RNA-guided surveillance complex from a bacterial immune system | Q30587075 | ||
| Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems | Q33960829 | ||
| CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies. | Q33985645 | ||
| CRISPRFinder: a web tool to identify clustered regularly interspaced short palindromic repeats | Q34004457 | ||
| Diversity, activity, and evolution of CRISPR loci in Streptococcus thermophilus | Q34008610 | ||
| CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation | Q34068759 | ||
| CRISPR/Cas system and its role in phage-bacteria interactions | Q34119422 | ||
| Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system | Q34166291 | ||
| Structural basis for CRISPR RNA-guided DNA recognition by Cascade | Q34175461 | ||
| Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence | Q34190309 | ||
| Crystal structure of clustered regularly interspaced short palindromic repeats (CRISPR)-associated Csn2 protein revealed Ca2+-dependent double-stranded DNA binding activity. | Q34194742 | ||
| Binding and cleavage of CRISPR RNA by Cas6 | Q34210424 | ||
| Mature clustered, regularly interspaced, short palindromic repeats RNA (crRNA) length is measured by a ruler mechanism anchored at the precursor processing site | Q34240056 | ||
| CRISPR interference directs strand specific spacer acquisition | Q34256881 | ||
| Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli | Q34259727 | ||
| Small RNAs in streptococci | Q34271953 | ||
| Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system | Q34287113 | ||
| Selective and hyperactive uptake of foreign DNA by adaptive immune systems of an archaeon via two distinct mechanisms. | Q34290429 | ||
| Molecular biology. A Swiss army knife of immunity | Q34294830 | ||
| Function and regulation of clustered regularly interspaced short palindromic repeats (CRISPR) / CRISPR associated (Cas) systems. | Q34314875 | ||
| Cleavage of phage DNA by the Streptococcus thermophilus CRISPR3-Cas system | Q34387539 | ||
| The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli | Q34631401 | ||
| CRISPR: New Horizons in Phage Resistance and Strain Identification | Q34634890 | ||
| The CRISPRs, they are a-changin': how prokaryotes generate adaptive immunity | Q34645309 | ||
| RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions | Q35064344 | ||
| Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference | Q35626315 | ||
| Rapid, accurate, computational discovery of Rho-independent transcription terminators illuminates their relationship to DNA uptake | Q35751629 | ||
| Cas5d processes pre-crRNA and is a member of a larger family of CRISPR RNA endonucleases | Q36342243 | ||
| Large scale variation in Enterococcus faecalis illustrated by the genome analysis of strain OG1RF. | Q36864751 | ||
| Archaeal CRISPR-based immune systems: exchangeable functional modules | Q37938333 | ||
| Innate and adaptive immunity in bacteria: mechanisms of programmed genetic variation to fight bacteriophages | Q37955485 | ||
| Memory of viral infections by CRISPR-Cas adaptive immune systems: acquisition of new information | Q38057517 | ||
| The CRISPR/Cas adaptive immune system of Pseudomonas aeruginosa mediates resistance to naturally occurring and engineered phages | Q41584259 | ||
| A CRISPR Approach to Gene Targeting | Q41896903 | ||
| The double-edged sword of CRISPR-Cas systems | Q42023704 | ||
| CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3 | Q42128481 | ||
| RNA in defense: CRISPRs protect prokaryotes against mobile genetic elements | Q42184018 | ||
| The highly dynamic CRISPR1 system of Streptococcus agalactiae controls the diversity of its mobilome. | Q46482246 | ||
| BLAST QuickStart: example-driven web-based BLAST tutorial | Q48076544 | ||
| The rise and fall of CRISPRs – dynamics of spacer acquisition and loss | Q50946708 | ||
| Comparative analysis of CRISPR loci in lactic acid bacteria genomes | Q52422277 | ||
| Helicase dissociation and annealing of RNA-DNA hybrids by Escherichia coli Cas3 protein. | Q52422434 | ||
| The crystal structure of the CRISPR-associated protein Csn2 from Streptococcus agalactiae | Q52422541 | ||
| RNA-mediated programmable DNA cleavage | Q54258192 | ||
| Cutadapt removes adapter sequences from high-throughput sequencing reads | Q55953584 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | CRISPR | Q412563 |
| Cas9 | Q16965677 | ||
| P304 | page(s) | 726-737 | |
| P577 | publication date | 2013-04-05 | |
| P1433 | published in | RNA Biology | Q7277167 |
| P1476 | title | The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems | |
| P478 | volume | 10 |
| Q42276515 | (Non-)translational medicine: targeting bacterial RNA |
| Q34002469 | A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion |
| Q92378292 | A Practical Guide to Genome Editing Using Targeted Nuclease Technologies |
| Q101166023 | A catalogue of biochemically diverse CRISPR-Cas9 orthologs |
| Q42005996 | A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of clustered regularly interspaced short palindromic repeats (crispr)-derived rnas (crrnas) in Haloferax volcanii |
| Q97520164 | A scoutRNA Is Required for Some Type V CRISPR-Cas Systems |
| Q42055024 | An active immune defense with a minimal CRISPR (clustered regularly interspaced short palindromic repeats) RNA and without the Cas6 protein |
| Q33660852 | An updated evolutionary classification of CRISPR-Cas systems |
| Q30374731 | Annotation and Classification of CRISPR-Cas Systems. |
| Q92040652 | Approaches to study CRISPR RNA biogenesis and the key players involved |
| Q89478669 | Bacterial expression, purification, and initial characterization of a full-length Cas13b protein from Porphyromonas gingivalis |
| Q38722587 | Bacterial group I introns: mobile RNA catalysts |
| Q26853377 | Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity |
| Q40585694 | CRISPR-Cas Systems Optimize Their Immune Response by Specifying the Site of Spacer Integration |
| Q46245620 | CRISPR-Cas Systems in Bacteroides fragilis, an Important Pathobiont in the Human Gut Microbiome |
| Q36973145 | CRISPR-Cas and Restriction-Modification Act Additively against Conjugative Antibiotic Resistance Plasmid Transfer in Enterococcus faecalis |
| Q92269691 | CRISPR-Cas in Streptococcus pyogenes |
| Q38196778 | CRISPR-Cas system: a powerful tool for genome engineering |
| Q29615781 | CRISPR-Cas systems for editing, regulating and targeting genomes |
| Q34040445 | CRISPR-Cas systems: beyond adaptive immunity |
| Q37697673 | CRISPR-Cas systems: new players in gene regulation and bacterial physiology |
| Q41971637 | CRISPR-Cas9-assisted recombineering in Lactobacillus reuteri |
| Q64085639 | CRISPR-Cas: Converting A Bacterial Defence Mechanism into A State-of-the-Art Genetic Manipulation Tool |
| Q34405661 | CRISPR-based technologies: prokaryotic defense weapons repurposed |
| Q24625361 | CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes |
| Q47696122 | CRISPR/Cas9-based genome editing of the filamentous fungi: the state of the art. |
| Q37630500 | CRISPR/Cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method. |
| Q41755483 | CRISPR/Cas9-mediated genome engineering: an adeno-associated viral (AAV) vector toolbox |
| Q38939889 | CRISPR/Cas9: a promising way to exploit genetic variation in plants |
| Q38614582 | CRISPR/Cas9: molecular tool for gene therapy to target genome and epigenome in the treatment of lung cancer |
| Q62029120 | CRISPR: a new principle of genome engineering linked to conceptual shifts in evolutionary biology |
| Q90298764 | CRISPRdisco: An Automated Pipeline for the Discovery and Analysis of CRISPR-Cas Systems |
| Q47921177 | Cas9 enhances bacterial virulence by repressing the regR transcriptional regulator in Streptococcus agalactiae |
| Q37643237 | Cas9-based tools for targeted genome editing and transcriptional control. |
| Q93137464 | Catalytically Active Cas9 Mediates Transcriptional Interference to Facilitate Bacterial Virulence |
| Q31096987 | Characterization of CRISPR RNA transcription by exploiting stranded metatranscriptomic data |
| Q26850610 | Classification and evolution of type II CRISPR-Cas systems |
| Q38602007 | Comparative Genomic Analysis Identifies a Campylobacter Clade Deficient in Selenium Metabolism |
| Q36117572 | Comparative genomic analysis identifies structural features of CRISPR-Cas systems in Riemerella anatipestifer |
| Q59656974 | Comparative genomics and evolution of trans-activating RNAs in Class 2 CRISPR-Cas systems |
| Q38855096 | Construction of a CRISPR-Cas9 System for Pig Genome Targeting |
| Q24669821 | Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system |
| Q36348284 | Crystal Structure of Staphylococcus aureus Cas9 |
| Q26783837 | Current and future prospects for CRISPR-based tools in bacteria |
| Q38687781 | Current application of CRISPR/Cas9 gene-editing technique to eradication of HIV/AIDS. |
| Q38454128 | DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes |
| Q28542520 | DNA binding properties of the small cascade subunit Csa5 |
| Q56610090 | Delivering CRISPR: a review of the challenges and approaches |
| Q41978232 | Detection and characterization of spacer integration intermediates in type I-E CRISPR-Cas system |
| Q28241526 | Development and applications of CRISPR-Cas9 for genome engineering |
| Q36166697 | Differential Distribution of Type II CRISPR-Cas Systems in Agricultural and Nonagricultural Campylobacter coli and Campylobacter jejuni Isolates Correlates with Lack of Shared Environments |
| Q21508512 | Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems |
| Q36256836 | Diversity and evolution of class 2 CRISPR-Cas systems |
| Q42701690 | Diversity and microevolution of CRISPR loci in Helicobacter cinaedi |
| Q26778564 | Diversity of CRISPR-Cas immune systems and molecular machines |
| Q42376316 | Editorial: Small Non-coding RNAs in Streptococci |
| Q52423088 | Efficient genome engineering in eukaryotes using Cas9 from Streptococcus thermophilus. |
| Q34481737 | Engineered CRISPR-Cas9 nucleases with altered PAM specificities |
| Q57202098 | Erratum: Corrigendum: A CRISPR/Cas system mediates bacterial innate immune evasion and virulence |
| Q43023581 | Evolution of adaptive immunity from transposable elements combined with innate immune systems |
| Q35062579 | Expanding the catalog of cas genes with metagenomes |
| Q38121774 | Exploiting CRISPR/Cas: interference mechanisms and applications. |
| Q35799763 | Filifactor alocis--a new emerging periodontal pathogen |
| Q38686595 | Functional roles of intrinsic disorder in CRISPR-associated protein Cas9. |
| Q92153117 | Genome editing using the endogenous type I CRISPR-Cas system in Lactobacillus crispatus |
| Q28252298 | Genome editing. The new frontier of genome engineering with CRISPR-Cas9 |
| Q41117712 | Genome-directed analysis of prophage excision, host defence systems, and central fermentative metabolism in Clostridium pasteurianum |
| Q39324308 | Genome-editing technologies and patent landscape overview. |
| Q34043392 | Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis |
| Q47745576 | Genomic diversity and distribution of Bifidobacterium longum subsp. longum across the human lifespan |
| Q35626874 | Global transcription of CRISPR loci in the human oral cavity |
| Q29114115 | Harnessing CRISPR-Cas9 immunity for genetic engineering |
| Q38498286 | High-Throughput Silencing Using the CRISPR-Cas9 System: A Review of the Benefits and Challenges |
| Q47614167 | Hypothesis: RNA and DNA Viral Sequence Integration into the Mammalian Host Genome Supports Long-Term B Cell and T Cell Adaptive Immunity |
| Q35554781 | I can see CRISPR now, even when phage are gone: a view on alternative CRISPR-Cas functions from the prokaryotic envelope |
| Q38192180 | Impact of CRISPR immunity on the emergence and virulence of bacterial pathogens |
| Q47436695 | In Planta Processing of the SpCas9-gRNA Complex |
| Q34043628 | In vivo genome editing using Staphylococcus aureus Cas9 |
| Q89784278 | Insights Obtained by Culturing Saccharibacteria With Their Bacterial Hosts |
| Q58758208 | Insights into the Human Virome Using CRISPR Spacers from Microbiomes |
| Q42592480 | Interference activity of a minimal Type I CRISPR-Cas system from Shewanella putrefaciens |
| Q37545745 | Lactobacillus buchneri genotyping on the basis of clustered regularly interspaced short palindromic repeat (CRISPR) locus diversity |
| Q28831343 | Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity |
| Q27010108 | Making designer mutants in model organisms |
| Q38919610 | Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity |
| Q92730750 | Modern Trends in Plant Genome Editing: An Inclusive Review of the CRISPR/Cas9 Toolbox |
| Q40662616 | Modulating the Cascade architecture of a minimal Type I-F CRISPR-Cas system |
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| Q89565540 | Prediction and diversity of tracrRNAs from type II CRISPR-Cas systems |
| Q36959817 | Processing-independent CRISPR RNAs limit natural transformation in Neisseria meningitidis |
| Q38649381 | Progress and prospects in plant genome editing. |
| Q29114114 | RNA sequencing uncovers antisense RNAs and novel small RNAs in Streptococcus pyogenes |
| Q48304493 | RNA-dependent RNA targeting by CRISPR-Cas9. |
| Q37366548 | RNA-guided genome editing for target gene mutations in wheat |
| Q37388903 | Repurposing CRISPR/Cas9 for in situ functional assays. |
| Q41995617 | Restriction-modification mediated barriers to exogenous DNA uptake and incorporation employed by Prevotella intermedia. |
| Q35100510 | Role of the Streptococcus mutans CRISPR-Cas systems in immunity and cell physiology. |
| Q40096303 | Single-cell sequencing unveils the lifestyle and CRISPR-based population history of Hydrotalea sp. in acid mine drainage. |
| Q42544832 | Special focus CRISPR-Cas |
| Q34514052 | Structure and Engineering of Francisella novicida Cas9. |
| Q27681624 | Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation |
| Q64124619 | Systematic prediction of genes functionally linked to CRISPR-Cas systems by gene neighborhood analysis |
| Q100515759 | Targeted mutagenesis of Mycoplasma gallisepticum using its endogenous CRISPR/Cas system |
| Q87182804 | Technical advances in the generation of transgenic animals and in their applications. Nantes, France, June 7th 2013 |
| Q26752309 | The Bacteriophage Carrier State of Campylobacter jejuni Features Changes in Host Non-coding RNAs and the Acquisition of New Host-derived CRISPR Spacer Sequences |
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| Q34522844 | The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA. |
| Q33688509 | The CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia |
| Q35842552 | The Cas6e ribonuclease is not required for interference and adaptation by the E. coli type I-E CRISPR-Cas system. |
| Q48145454 | The Impact of DNA Topology and Guide Length on Target Selection by a Cytosine-Specific Cas9. |
| Q91725125 | The effects of CRISPR-Cas9 knockout of the TGF-β1 gene on antler cartilage cells in vitro |
| Q38237006 | The new CRISPR-Cas system: RNA-guided genome engineering to efficiently produce any desired genetic alteration in animals. |
| Q37643438 | The role of CRISPR-Cas systems in virulence of pathogenic bacteria |
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| Q38788714 | To CRISPR and beyond: the evolution of genome editing in stem cells |
| Q52430861 | Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors. |
| Q46302986 | Use of the Cas9 Orthologs from Streptococcus thermophilus and Staphylococcus aureus for Non-Homologous End-Joining Mediated Site-Specific Mutagenesis in Arabidopsis thaliana |
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