| scholarly article | Q13442814 |
| P50 | author | Emmanuelle Charpentier | Q17280087 |
| Peter Fineran | Q42092554 | ||
| P2860 | cites work | Csy4 is responsible for CRISPR RNA processing in Pectobacterium atrosepticum | Q52422407 |
| Helicase dissociation and annealing of RNA-DNA hybrids by Escherichia coli Cas3 protein. | Q52422434 | ||
| A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes | Q21090166 | ||
| A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action | Q21203780 | ||
| The CRISPRdb database and tools to display CRISPRs and to generate dictionaries of spacers and repeats | Q21284230 | ||
| CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes | Q21508827 | ||
| Virioplankton: Viruses in Aquatic Ecosystems | Q22061799 | ||
| CRISPR-based adaptive immune systems | Q24609425 | ||
| CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III | Q24628207 | ||
| A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity | Q24669850 | ||
| Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product | Q24679073 | ||
| A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats | Q27650625 | ||
| Cas6 is an endoribonuclease that generates guide RNAs for invader defense in prokaryotes | Q27653417 | ||
| Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated genome defense | Q27655927 | ||
| Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease | Q27664403 | ||
| Structure of a CRISPR-associated protein Cas2 fromDesulfovibrio vulgaris | Q27666215 | ||
| A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair | Q27666531 | ||
| Structural and Functional Characterization of an Archaeal Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Complex for Antiviral Defense (CASCADE) | Q27667493 | ||
| Structural and Biochemical Analysis of Nuclease Domain of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Protein 3 (Cas3) | Q27670901 | ||
| Cas5d Protein Processes Pre-crRNA and Assembles into a Cascade-like Interference Complex in Subtype I-C/Dvulg CRISPR-Cas System | Q27670930 | ||
| Ecology of prokaryotic viruses | Q28258560 | ||
| Small CRISPR RNAs guide antiviral defense in prokaryotes | Q28290898 | ||
| The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA | Q28297640 | ||
| In vivo protein interactions and complex formation in the Pectobacterium atrosepticum subtype I-F CRISPR/Cas System | Q28485452 | ||
| RNA-guided genetic silencing systems in bacteria and archaea | Q29614421 | ||
| CRISPR/Cas, the immune system of bacteria and archaea | Q29614423 | ||
| Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements | Q29615788 | ||
| Evolution and classification of the CRISPR-Cas systems | Q29616645 | ||
| Phage response to CRISPR-encoded resistance in Streptococcus thermophilus | Q29617060 | ||
| Innate and adaptive immunity in bacteria: mechanisms of programmed genetic variation to fight bacteriophages | Q37955485 | ||
| Analysis of the three Yersinia pestis CRISPR loci provides new tools for phylogenetic studies and possibly for the investigation of ancient DNA. | Q41446390 | ||
| The CRISPR/Cas adaptive immune system of Pseudomonas aeruginosa mediates resistance to naturally occurring and engineered phages | Q41584259 | ||
| CRISPR distribution within the Escherichia coli species is not suggestive of immunity-associated diversifying selection. | Q41894905 | ||
| Characterization of CRISPR RNA processing in Clostridium thermocellum and Methanococcus maripaludis | Q41995245 | ||
| CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3 | Q42128481 | ||
| The highly dynamic CRISPR1 system of Streptococcus agalactiae controls the diversity of its mobilome. | Q46482246 | ||
| Long tandemly repeated repetitive (LTRR) sequences in the filamentous cyanobacterium Anabaena sp. PCC 7120. | Q48063355 | ||
| The rise and fall of CRISPRs – dynamics of spacer acquisition and loss | Q50946708 | ||
| Comparative analysis of CRISPR loci in lactic acid bacteria genomes | Q52422277 | ||
| Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin | Q29617073 | ||
| CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea | Q29617488 | ||
| Structures of the RNA-guided surveillance complex from a bacterial immune system | Q30587075 | ||
| The small, slow and specialized CRISPR and anti-CRISPR of Escherichia and Salmonella | Q33608753 | ||
| Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems | Q33960829 | ||
| CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies. | Q33985645 | ||
| CRISPRFinder: a web tool to identify clustered regularly interspaced short palindromic repeats | Q34004457 | ||
| Diversity, activity, and evolution of CRISPR loci in Streptococcus thermophilus | Q34008610 | ||
| Bacteriophage resistance mechanisms | Q34021879 | ||
| Analysis of streptococcal CRISPRs from human saliva reveals substantial sequence diversity within and between subjects over time. | Q34024986 | ||
| CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation | Q34068759 | ||
| CRISPR/Cas system and its role in phage-bacteria interactions | Q34119422 | ||
| Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system | Q34166291 | ||
| Structural basis for CRISPR RNA-guided DNA recognition by Cascade | Q34175461 | ||
| Mature clustered, regularly interspaced, short palindromic repeats RNA (crRNA) length is measured by a ruler mechanism anchored at the precursor processing site | Q34240056 | ||
| CRISPR interference directs strand specific spacer acquisition | Q34256881 | ||
| Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli | Q34259727 | ||
| Experimental definition of a clustered regularly interspaced short palindromic duplicon in Escherichia coli | Q34286625 | ||
| Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system | Q34287113 | ||
| Selective and hyperactive uptake of foreign DNA by adaptive immune systems of an archaeon via two distinct mechanisms. | Q34290429 | ||
| Double-stranded Endonuclease Activity in Bacillus halodurans Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Cas2 Protein | Q34297176 | ||
| Nature of DNA polymorphism in the direct repeat cluster of Mycobacterium tuberculosis; application for strain differentiation by a novel typing method | Q34323913 | ||
| The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli | Q34631401 | ||
| CRISPR: New Horizons in Phage Resistance and Strain Identification | Q34634890 | ||
| On-line resources for bacterial micro-evolution studies using MLVA or CRISPR typing | Q34682070 | ||
| Virus population dynamics and acquired virus resistance in natural microbial communities | Q34780702 | ||
| Short motif sequences determine the targets of the prokaryotic CRISPR defence system | Q34953078 | ||
| SSO1450--a CAS1 protein from Sulfolobus solfataricus P2 with high affinity for RNA and DNA. | Q34980083 | ||
| RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions | Q35064344 | ||
| Bacteriophage genomics | Q35565615 | ||
| Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference | Q35626315 | ||
| Evidence of a robust resident bacteriophage population revealed through analysis of the human salivary virome | Q35896326 | ||
| Characterization of the CRISPR/Cas subtype I-A system of the hyperthermophilic crenarchaeon Thermoproteus tenax | Q35943228 | ||
| Crystal structure of hypothetical protein TTHB192 from Thermus thermophilus HB8 reveals a new protein family with an RNA recognition motif-like domain | Q36458420 | ||
| CRISPR-based adaptive and heritable immunity in prokaryotes | Q37568446 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | CRISPR | Q412563 |
| P304 | page(s) | 202-209 | |
| P577 | publication date | 2012-11-02 | |
| P1433 | published in | Virology | Q7934867 |
| P1476 | title | Memory of viral infections by CRISPR-Cas adaptive immune systems: acquisition of new information | |
| P478 | volume | 434 |
| Q26741371 | A Broad Overview and Review of CRISPR-Cas Technology and Stem Cells |
| Q27000786 | A CRISPR method for genome engineering |
| Q34002469 | A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion |
| Q37458207 | A PNPase dependent CRISPR System in Listeria |
| Q92378292 | A Practical Guide to Genome Editing Using Targeted Nuclease Technologies |
| Q46926254 | Accurate computational prediction of the transcribed strand of CRISPR non-coding RNAs. |
| Q42204197 | Adaptation in bacterial CRISPR-Cas immunity can be driven by defective phages. |
| Q37606958 | Adaptation of the Haloarcula hispanica CRISPR-Cas system to a purified virus strictly requires a priming process |
| Q38210066 | Adapting to new threats: the generation of memory by CRISPR-Cas immune systems |
| Q35931297 | An Active Type I-E CRISPR-Cas System Identified in Streptomyces avermitilis |
| Q48090179 | Anti-cas spacers in orphan CRISPR4 arrays prevent uptake of active CRISPR-Cas I-F systems |
| Q39306038 | Applications of CRISPR/Cas9 in retinal degenerative diseases |
| Q41146102 | Asymmetric positioning of Cas1-2 complex and Integration Host Factor induced DNA bending guide the unidirectional homing of protospacer in CRISPR-Cas type I-E system |
| Q28657639 | Bacterial genome instability |
| Q59353665 | Bioinformatic evidence of widespread priming in type I and II CRISPR-Cas systems |
| Q34526018 | Breaking-Cas-interactive design of guide RNAs for CRISPR-Cas experiments for ENSEMBL genomes |
| Q26824296 | CRISPR interference: a structural perspective |
| Q38692105 | CRISPR-Cas adaptation: insights into the mechanism of action |
| Q42334840 | CRISPR-Cas adaptive immunity and the three Rs. |
| Q34114614 | CRISPR-Cas immunity and mobile DNA: a new superfamily of DNA transposons encoding a Cas1 endonuclease |
| Q92269691 | CRISPR-Cas in Streptococcus pyogenes |
| Q29615781 | CRISPR-Cas systems for editing, regulating and targeting genomes |
| Q41958555 | CRISPR-Cas systems preferentially target the leading regions of MOBF conjugative plasmids. |
| Q27014828 | CRISPR-Cas systems: Prokaryotes upgrade to adaptive immunity |
| Q37697673 | CRISPR-Cas systems: new players in gene regulation and bacterial physiology |
| Q36149464 | CRISPR-Cas9-mediated genome editing and guide RNA design |
| Q39225316 | CRISPR-Cas: Adapting to change |
| Q28069426 | CRISPR-Cas: biology, mechanisms and relevance |
| Q37079803 | CRISPR-Cas: evolution of an RNA-based adaptive immunity system in prokaryotes |
| Q34330105 | CRISPR-spacer integration reporter plasmids reveal distinct genuine acquisition specificities among CRISPR-Cas I-E variants of Escherichia coli |
| Q39185865 | CRISPR/Cas9-mediated genome editing in plants |
| Q38614582 | CRISPR/Cas9: molecular tool for gene therapy to target genome and epigenome in the treatment of lung cancer |
| Q42700233 | CRISPR: A Useful Genetic Feature to Follow Vaginal Carriage of Group B Streptococcus |
| Q36019329 | CRISPRDetect: A flexible algorithm to define CRISPR arrays |
| Q37079810 | CRISPRTarget: bioinformatic prediction and analysis of crRNA targets. |
| Q27015486 | CRISPR‐Cas systems and RNA‐guided interference |
| Q89834538 | Cas3 Protein-A Review of a Multi-Tasking Machine |
| Q36140262 | Casposon integration shows strong target site preference and recapitulates protospacer integration by CRISPR-Cas systems |
| Q41976115 | Chromosomal targeting by CRISPR-Cas systems can contribute to genome plasticity in bacteria. |
| Q42104489 | Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 Genetic Engineering: Robotic Genetic Surgery |
| Q35120736 | Comparative analysis of CRISPR cassettes from the human gut metagenomic contigs |
| Q26829917 | Comparative genomics of defense systems in archaea and bacteria |
| Q30374204 | Cpf1 nucleases demonstrate robust activity to induce DNA modification by exploiting homology directed repair pathways in mammalian cells. |
| Q34699789 | Cytotoxic chromosomal targeting by CRISPR/Cas systems can reshape bacterial genomes and expel or remodel pathogenicity islands |
| Q36914654 | DNA motifs determining the accuracy of repeat duplication during CRISPR adaptation in Haloarcula hispanica |
| Q35142271 | Degenerate target sites mediate rapid primed CRISPR adaptation. |
| Q59352119 | Development of Direct-acting Antiviral and Host-targeting Agents for Treatment of HBV Infection |
| Q40310719 | Different genome stability proteins underpin primed and naïve adaptation in E. coli CRISPR-Cas immunity. |
| Q34536517 | Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems |
| Q26778564 | Diversity of CRISPR-Cas immune systems and molecular machines |
| Q30252615 | Dynamics of adaptive immunity against phage in bacterial populations. |
| Q44871454 | Editor's Highlight: OrganophosphateDiazinon Altered Quorum Sensing, Cell Motility, Stress Response, and Carbohydrate Metabolism of Gut Microbiome. |
| Q39402483 | Evolutionary Genomics of Defense Systems in Archaea and Bacteria |
| Q90928445 | Extrachromosomal circular elements targeted by CRISPR-Cas in Dehalococcoides mccartyi are linked to mobilization of reductive dehalogenase genes |
| Q35686057 | Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9. |
| Q56809227 | Functions and Applications of RNA-Guided CRISPR-Cas Immune Systems |
| Q26752462 | Gene Targeting Using Homologous Recombination in Embryonic Stem Cells: The Future for Behavior Genetics? |
| Q26769662 | Genome-editing Technologies for Gene and Cell Therapy |
| Q34722556 | Genome-wide identification of regulatory RNAs in the human pathogen Clostridium difficile. |
| Q34533684 | Genomics-Based Exploration of Virulence Determinants and Host-Specific Adaptations of Pseudomonas syringae Strains Isolated from Grasses |
| Q30542434 | Holding a grudge: persisting anti-phage CRISPR immunity in multiple human gut microbiomes |
| Q40468504 | Host diversity limits the evolution of parasite local adaptation. |
| Q26748886 | In Vivo Delivery Systems for Therapeutic Genome Editing |
| Q97438364 | In vivo gene delivery mediated by non-viral vectors for cancer therapy |
| Q41429543 | Interference-driven spacer acquisition is dominant over naive and primed adaptation in a native CRISPR-Cas system |
| Q42085326 | Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition |
| Q41019432 | Linking environmental prokaryotic viruses and their host through CRISPRs |
| Q34124570 | NilD CRISPR RNA contributes to Xenorhabdus nematophila colonization of symbiotic host nematodes |
| Q52431943 | Non-viral delivery systems for CRISPR/Cas9-based genome editing: Challenges and opportunities |
| Q38215794 | Novel aspects of RNA regulation in Staphylococcus aureus |
| Q42092486 | Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer. |
| Q37079815 | Programmable plasmid interference by the CRISPR-Cas system inThermococcus kodakarensis |
| Q34350509 | Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system |
| Q33895336 | Pseudo-chaotic oscillations in CRISPR-virus coevolution predicted by bifurcation analysis |
| Q27025675 | RNA-guided CRISPR-Cas technologies for genome-scale investigation of disease processes |
| Q26744073 | Recent Advances in Genome Editing Using CRISPR/Cas9 |
| Q41128005 | Regulation of the Type I-F CRISPR-Cas system by CRP-cAMP and GalM controls spacer acquisition and interference |
| Q42287283 | Right of admission reserved, no matter the path |
| Q47894799 | Role of free DNA ends and protospacer adjacent motifs for CRISPR DNA uptake in Pyrococcus furiosus |
| Q46462953 | Six-legged walking in insects: how CPGs, peripheral feedback, and descending signals generate coordinated and adaptive motor rhythms |
| Q34122750 | Small regulatory RNAs in Archaea |
| Q39014913 | Small regulatory RNAs in Streptococcus pneumoniae: discovery and biological functions |
| Q47267064 | Solution structure and dynamics of Xanthomonas albilineans Cas2 provide mechanistic insight on nuclease activity |
| Q37518596 | Staphylococcus epidermidis Csm1 is a 3'-5' exonuclease |
| Q52430895 | Structural insights into the inactivation of CRISPR-Cas systems by diverse anti-CRISPR proteins |
| Q92387375 | Systematic analysis of Type I-E Escherichia coli CRISPR-Cas PAM sequences ability to promote interference and primed adaptation |
| Q28085767 | The CRISPR system can correct or modify the expression of genes responsible for hereditary diseases |
| Q36461912 | The CRISPR-associated Csx1 protein of Pyrococcus furiosus is an adenosine-specific endoribonuclease |
| Q40539458 | The Influence of Copy-Number of Targeted Extrachromosomal Genetic Elements on the Outcome of CRISPR-Cas Defense |
| Q36370829 | The casposon-encoded Cas1 protein from Aciduliprofundum boonei is a DNA integrase that generates target site duplications |
| Q89766835 | The size of the immune repertoire of bacteria |
| Q33636101 | The spacer size of I-B CRISPR is modulated by the terminal sequence of the protospacer |
| Q34337685 | The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems |
| Q27680484 | Toroidal Structure and DNA Cleavage by the CRISPR-Associated [4Fe-4S] Cluster Containing Cas4 Nuclease SSO0001 from Sulfolobus solfataricus |
| Q28652004 | Transcriptomic analysis of Clostridium thermocellum Populus hydrolysate-tolerant mutant strain shows increased cellular efficiency in response to Populus hydrolysate compared to the wild type strain |
| Q41904442 | Two CRISPR-Cas systems in Methanosarcina mazei strain Gö1 display common processing features despite belonging to different types I and III. |
| Q41265458 | Two distinct DNA binding modes guide dual roles of a CRISPR-Cas protein complex. |
| Q39376221 | Type II CRISPR/Cas9 approach in the oncological therapy |
| Q38468273 | Utilization of TALEN and CRISPR/Cas9 technologies for gene targeting and modification |
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