Accumulation of recessive lethal mutations in Saccharomyces cerevisiae mlh1 mismatch repair mutants is not associated with gross chromosomal rearrangements

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Accumulation of recessive lethal mutations in Saccharomyces cerevisiae mlh1 mismatch repair mutants is not associated with gross chromosomal rearrangements is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1534/GENETICS.106.059311
P932PMC publication ID1569777
P698PubMed publication ID16816424
P5875ResearchGate publication ID6969258

P50authorDavid BotsteinQ1173787
P2093author name stringEric Alani
David Gresham
Julie Akiko Heck
P2860cites workCharacterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functionsQ27932283
SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombinationQ27935480
Direct estimate of the mutation rate and the distribution of fitness effects in the yeast Saccharomyces cerevisiaeQ28362113
Rapid accumulation of mutations during seed-to-seed propagation of mismatch-repair-defective ArabidopsisQ33340572
The role of mismatch repair in the prevention of base pair mutations in Saccharomyces cerevisiaeQ33592366
Variation in efficiency of DNA mismatch repair at different sites in the yeast genomeQ33854065
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6.Q33950079
Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2.Q33951095
Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrityQ34012568
Deficient DNA mismatch repair: a common etiologic factor for colon cancerQ34189020
Characteristic genome rearrangements in experimental evolution of Saccharomyces cerevisiaeQ34415662
Systematic mutagenesis of the Saccharomyces cerevisiae MLH1 gene reveals distinct roles for Mlh1p in meiotic crossing over and in vegetative and meiotic mismatch repairQ34463536
Negative epistasis between natural variants of the Saccharomyces cerevisiae MLH1 and PMS1 genes results in a defect in mismatch repairQ34480201
The hereditary nonpolyposis colorectal cancer syndrome: genetics and clinical implicationsQ34532407
The consequences of growth of a mutator strain of Escherichia coli as measured by loss of function among multiple gene targets and loss of fitnessQ34609052
Sequence composition and context effects on the generation and repair of frameshift intermediates in mononucleotide runs in Saccharomyces cerevisiae.Q34610604
Estimates of the rate and distribution of fitness effects of spontaneous mutation in Saccharomyces cerevisiaeQ34611665
Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants.Q36568353
Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL geneQ36643609
Biochemical characterization of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 complex and mispaired bases in DNA.Q38320783
Mlh1 is unique among mismatch repair proteins in its ability to promote crossing-over during meiosisQ38344945
Control of large chromosomal duplications in Escherichia coli by the mismatch repair systemQ42962535
Shaping of tumor and drug-resistant genomes by instability and selectionQ44508745
Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites.Q52563158
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectDNA mismatch repairQ2984243
Saccharomyces cerevisiaeQ719725
P304page(s)519-523
P577publication date2006-07-02
P1433published inGeneticsQ3100575
P1476titleAccumulation of recessive lethal mutations in Saccharomyces cerevisiae mlh1 mismatch repair mutants is not associated with gross chromosomal rearrangements
P478volume174

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cites work (P2860)
Q36648733A Computational Approach to Estimating Nondisjunction Frequency in Saccharomyces cerevisiae.
Q33940504Clusters of nucleotide substitutions and insertion/deletion mutations are associated with repeat sequences
Q34196484Detection of heterozygous mutations in the genome of mismatch repair defective diploid yeast using a Bayesian approach
Q41090428Eric Lander and David Botstein on Mapping Quantitative Traits
Q27312240Evolution of mutational robustness in the yeast genome: a link to essential genes and meiotic recombination hotspots
Q34187406Genomic mutation rates: what high-throughput methods can tell us
Q27012760Multiple cellular mechanisms prevent chromosomal rearrangements involving repetitive DNA
Q36128650Mutation hot spots in yeast caused by long-range clustering of homopolymeric sequences
Q64082866Yeast expression of mammalian Onzin and fungal FCR1 suggests ancestral functions of PLAC8 proteins in mitochondrial metabolism and DNA repair

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