Quercetin and cancer chemoprevention

scientific article

Quercetin and cancer chemoprevention is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1093/ECAM/NEQ053
P932PMC publication ID3136711
P698PubMed publication ID21792362
P5875ResearchGate publication ID51524105

P50authorSara De BiasiQ82958176
Lara GibelliniQ114404433
Erika RoatQ117266261
Linda BertoncelliQ117266266
Jonas P MontagnaQ117266267
Marcello PintiQ41701743
Milena NasiQ38804449
Andrea CossarizzaQ38804464
P2093author name stringEdwin L Cooper
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Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids in macrophage J774A.1.Q32049448
Characterization of cells with different mitochondrial membrane potential during apoptosisQ33223961
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Risk factors for Barrett's oesophagus and oesophageal adenocarcinoma: results from the FINBAR studyQ34099177
Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability.Q34146784
Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal productQ77799982
Decreased B16F10 melanoma growth and impaired tumour vascularization in BDF1 mice with quercetin-cyclodextrin binary systemQ79224263
Suppression of tumor growth and invasion in 9,10 dimethyl benz(a) anthracene induced mammary carcinoma by the plant bioflavonoid quercetinQ79920810
Flavonoid intake and colorectal cancer risk in men and womenQ80148268
A prospective study of dietary flavonoid intake and incidence of epithelial ovarian cancerQ80244055
Role of p53 in antioxidant defense of HPV-positive cervical carcinoma cells following H2O2 exposureQ80475029
Antioxidative and prooxidative effects of quercetin on A549 cellsQ80510195
Liposomal quercetin efficiently suppresses growth of solid tumors in murine modelsQ83364602
p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis.Q40571016
Quercetin in our diet: from potent mutagen to probable anticarcinogenQ40655710
Tumor promotion by hydrogen peroxide in rat liver epithelial cellsQ40962781
Dietary flavonoid intake and lung cancer--a population-based case-control study.Q41277914
Cranberry and grape seed extracts inhibit the proliferative phenotype of oral squamous cell carcinomasQ41788832
Protective effect of quercetin in primary neurons against Abeta(1-42): relevance to Alzheimer's diseaseQ41975964
Vaccinium myrtillus (Bilberry) Extracts Reduce Angiogenesis In Vitro and In VivoQ42009141
Carcinogenicity examination of quercetin and rutin in ACI ratsQ42471811
In vitro cytotoxic effect of Brazilian green propolis on human laryngeal epidermoid carcinoma (HEp-2) cellsQ42662497
Ethanolic Extract of Propolis Augments TRAIL-Induced Apoptotic Death in Prostate Cancer CellsQ42822464
Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites.Q43002840
Intake of flavonols and flavones and risk of coronary heart disease in male smokersQ43515477
Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groupsQ43548576
Pre-clinical and clinical study of QC12, a water-soluble, pro-drug of quercetinQ43573411
Flavonoid glucuronides are substrates for human liver beta-glucuronidaseQ43713502
Human metabolism of dietary flavonoids: identification of plasma metabolites of quercetinQ43866518
Food-derived polyphenols inhibit pancreatic cancer growth through mitochondrial cytochrome C release and apoptosisQ43938062
Reactive oxygen species stimulated human hepatoma cell proliferation via cross-talk between PI3-K/PKB and JNK signaling pathwaysQ44166293
International renal cell cancer study. VII. Role of dietQ44173069
Perturbation of microtubule polymerization by quercetin through tubulin binding: a novel mechanism of its antiproliferative activityQ44186752
Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: the role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolismQ44277902
Oxidized quercetin reacts with thiols rather than with ascorbate: implication for quercetin supplementationQ44546815
The antioxidant, rather than prooxidant, activities of quercetin on normal cells: quercetin protects mouse thymocytes from glucose oxidase-mediated apoptosis.Q44673144
Consumption of vegetables and fruit and the risk of bladder cancer in the European Prospective Investigation into Cancer and NutritionQ44689781
Cytotoxicity of flavonoids toward cultured normal human cellsQ45246526
A mechanism-based antioxidant approach for the reduction of skin carcinogenesisQ45285576
Cruciferous vegetables in relation to renal cell carcinoma.Q45947701
Cytotoxicity of flavones and flavonols to a human esophageal squamous cell carcinoma cell line (KYSE-510) by induction of G2/M arrest and apoptosis.Q46034803
Nanoencapsulation of quercetin enhances its dietary efficacy in combating arsenic-induced oxidative damage in liver and brain of ratsQ46226798
Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulationQ46267730
Quercetin inhibits lymphocyte activation and proliferation without inducing apoptosis in peripheral mononuclear cellsQ46387103
Vesicular flavonoid in combating diethylnitrosamine induced hepatocarcinoma in rat model.Q46390126
Overexpression of a novel superoxide-producing enzyme, NADPH oxidase 1, in adenoma and well differentiated adenocarcinoma of the human colonQ46410328
Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin).Q46438701
Flavonoid intake and risk of pancreatic cancer in male smokers (Finland).Q46694723
Quercetin in w/o microemulsion: in vitro and in vivo skin penetration and efficacy against UVB-induced skin damages evaluated in vivoQ46730092
The reversibility of the glutathionyl-quercetin adduct spreads oxidized quercetin-induced toxicityQ46771640
Flavonoids and the risk of renal cell carcinomaQ46786814
Quercetin arrests G2/M phase and induces caspase-dependent cell death in U937 cellsQ46794275
The effects of quercetin on antioxidant status and tumor markers in the lung and serum of mice treated with benzo(a)pyreneQ46867649
Modulation of interleukin-1beta mediated inflammatory response in human astrocytes by flavonoids: implications in neuroprotectionQ48169090
Food groups and renal cell carcinoma: a case-control study from Italy.Q50717406
Prevention of 1,2-dimethylhydrazine-induced circulatory oxidative stress by bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione during colon carcinogenesis.Q53346186
Effects of UV light and tumor promoters on endogenous vitamin E status in mouse skin.Q53414068
Dietary antioxidants and lung cancer risk: a case-control study in Uruguay.Q53420087
Lack of carcinogenicity of quercetin in F344/DuCrj rats.Q53516118
NAG-1 up-regulation mediated by EGR-1 and p53 is critical for quercetin-induced apoptosis in HCT116 colon carcinoma cells.Q53581939
Flavonoids of cocoa inhibit recombinant human 5-lipoxygenase.Q54319903
Combination treatment with curcumin and quercetin of adenomas in familial adenomatous polyposis.Q54463937
Polyphenols: Chemistry, Dietary Sources, Metabolism, and Nutritional SignificanceQ56610830
Dietary Flavonoids and the Risk of Colorectal CancerQ57569947
Fruit and vegetable consumption in the prevention of oesophageal and cardia cancersQ58204790
Induction of sperm abnormalities in mice by quercetinQ69720411
Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The NetherlandsQ70517510
Quercetin, a rat intestinal and bladder carcinogen present in bracken fern (Pteridium aquilinum)Q71393634
Antioxidant activity of resveratrol in red wineQ71581809
Time course of induction of rat hepatic drug-metabolizing enzyme activities following dietary administration of flavonoidsQ71901258
Enhancement of T cell receptor signaling by a mild oxidative shift in the intracellular thiol poolQ73086182
Dietary flavonoids: intake, health effects and bioavailabilityQ73132209
Prospective study of fruit and vegetable consumption and risk of lung cancer among men and womenQ73191054
Prooxidant activity of flavonoids: copper-dependent strand breaks and the formation of 8-hydroxy-2'-deoxyguanosine in DNAQ73294746
Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potentialQ74081784
Inhibition of xanthine oxidase by purpurogallin and silymarin groupQ74500768
Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant propertiesQ74586431
Flavonoid antioxidantsQ34263068
The contribution of endogenous sources of DNA damage to the multiple mutations in cancerQ34263814
Skin tumor-promoting activity of benzoyl peroxide, a widely used free radical-generating compoundQ34269720
Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stressesQ34301424
Role of oxygen radicals in DNA damage and cancer incidence.Q34383781
Review of the biology of Quercetin and related bioflavonoidsQ34401033
(-)-Epigallocatechin-3-gallate (EGCG) sensitizes melanoma cells to interferon induced growth inhibition in a mouse model of human melanomaQ34530415
The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma.Q34532264
Curcumin in cell death processes: a challenge for CAM of age-related pathologiesQ34580050
Prospective study of fruit and vegetable intake and risk of prostate cancerQ34581329
Fruit, vegetables, and colorectal cancer risk: the European Prospective Investigation into Cancer and NutritionQ34606105
Induction of apoptosis in human bladder cancer cells by green tea catechinsQ34611519
Cell growth inhibition and gene expression regulation by (-)-epigallocatechin-3-gallate in human cervical cancer cellsQ34612226
The dietary flavonoids myricetin and fisetin act as dual inhibitors of DNA topoisomerases I and II in cellsQ34615057
Epicatechins Purified from Green Tea (Camellia sinensis) Differentially Suppress Growth of Gender-Dependent Human Cancer Cell Lines.Q34667547
Induction of tumors in ACI rats given a diet containing ptaquiloside, a bracken carcinogen.Q34688794
Molecular targets for nutrients involved with cancer preventionQ34718681
Cancer prevention -- the potential for diet to modulate molecular signallingQ35043753
Radical causes of cancer.Q35097371
Aqueous Extract of Shi-Liu-Wei-Liu-Qi-Yin Induces G2/M Phase Arrest and Apoptosis in Human Bladder Carcinoma Cells via Fas and Mitochondrial PathwayQ35102010
Assessment of the Antioxidant and Reactive Oxygen Species Scavenging Activity of Methanolic Extract of Caesalpinia crista Leaf.Q35104965
Inhibition of prostate cancer cell colony formation by the flavonoid quercetin correlates with modulation of specific regulatory genesQ35541796
Oxidative stress and cell signallingQ35768393
Suppression of tumour development by substances derived from the diet--mechanisms and clinical implicationsQ35803133
Flavonoids and breast cancer risk in ItalyQ36095499
Dietary cancer-chemopreventive compounds: from signaling and gene expression to pharmacological effectsQ36145133
Nox1 expression determines cellular reactive oxygen and modulates c-fos-induced growth factor, interleukin-8, and Cav-1.Q36202911
The roles of polyphenols in cancer chemopreventionQ36528356
The quercetin paradoxQ36632544
Effects of dietary flavonoids on apoptotic pathways related to cancer chemopreventionQ36744963
Ins and outs of dietary phytochemicals in cancer chemoprevention.Q36768726
Flavonoids: hemisynthesis, reactivity, characterization and free radical scavenging activity.Q36982391
Comprehensive review of cancer chemopreventive agents evaluated in experimental carcinogenesis models and clinical trialsQ37160786
Perspectives for cancer prevention with natural compoundsQ37212228
Preventive effect of the flavonoid, quercetin, on hepatic cancer in rats via oxidant/antioxidant activity: molecular and histological evidencesQ37238526
Dietary patterns and breast cancer risk in women participating in the Black Women's Health StudyQ37309720
Effects of low dose quercetin: cancer cell-specific inhibition of cell cycle progressionQ37330137
Mitochondrial redox signaling by p66Shc is involved in regulating androgenic growth stimulation of human prostate cancer cells.Q37419562
Antihypertensive effects of the flavonoid quercetinQ37421163
Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevityQ37432488
Differential growth suppression of human melanoma cells by tea (Camellia sinensis) epicatechins (ECG, EGC and EGCG).Q38498201
Quercetin augments TRAIL-induced apoptotic death: involvement of the ERK signal transduction pathwayQ39226135
Quercetin enhances TRAIL-induced apoptosis in prostate cancer cells via increased protein stability of death receptor 5.Q39748934
Induction of apoptosis by quercetin is mediated through AMPKalpha1/ASK1/p38 pathwayQ39750640
Apoptosis induction effects of EGCG in laryngeal squamous cell carcinoma cells through telomerase repressionQ39794467
Quercetin-induced apoptosis acts through mitochondrial- and caspase-3-dependent pathways in human breast cancer MDA-MB-231 cellsQ39799455
Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cellsQ39805372
Reactive oxygen species and lipoxygenases regulate the oncogenicity of NPM-ALK-positive anaplastic large cell lymphomasQ39841585
Quercetin inhibit human SW480 colon cancer growth in association with inhibition of cyclin D1 and survivin expression through Wnt/beta-catenin signaling pathwayQ39851799
Identification of epigallocatechin-3-gallate in green tea polyphenols as a potent inducer of p53-dependent apoptosis in the human lung cancer cell line A549.Q39858365
Quercetin is able to demethylate the p16INK4a gene promoterQ39922945
Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cellsQ39923672
A novel antioxidant function for the tumor-suppressor gene p53 in the retinal ganglion cellQ39980959
(-)-Epigallocatechin gallate induced apoptosis in human adrenal cancer NCI-H295 cells through caspase-dependent and caspase-independent pathway.Q39982614
Stabilization of p53 is involved in quercetin-induced cell cycle arrest and apoptosis in HepG2 cellsQ40005223
Quercetin induces cell cycle G1 arrest through elevating Cdk inhibitors p21 and p27 in human hepatoma cell line (HepG2).Q40129163
Quercetin downregulates matrix metalloproteinases 2 and 9 proteins expression in prostate cancer cells (PC-3).Q40286264
Inhibition of Mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activityQ40291546
Essential requirement of reduced glutathione (GSH) for the anti-oxidant effect of the flavonoid quercetinQ40349362
Inhibition of lung cancer cell growth by quercetin glucuronides via G2/M arrest and induction of apoptosisQ40352598
Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expressionQ40418488
Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expressionQ40443907
Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cellsQ40509371
Increased Nox1 and hydrogen peroxide in prostate cancerQ40511475
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P304page(s)591356
P577publication date2011-04-14
P1433published inEvidence-based Complementary and Alternative MedicineQ5418319
P1476titleQuercetin and cancer chemoprevention
P478volume2011

Reverse relations

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