| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1994PNAS...91.4057P |
| P356 | DOI | 10.1073/PNAS.91.9.4057 |
| P932 | PMC publication ID | 43722 |
| P698 | PubMed publication ID | 7909610 |
| P5875 | ResearchGate publication ID | 15288843 |
| P2093 | author name string | J Alexander | |
| E Appella | |||
| A Sette | |||
| D M Page | |||
| H M Grey | |||
| K Snoke | |||
| S M Hedrick | |||
| P2860 | cites work | T cell receptor antagonist peptides induce positive selection | Q29618820 |
| Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events | Q36191499 | ||
| In vivo and in vitro clonal deletion of double-positive thymocytes | Q36231231 | ||
| Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cells | Q36350774 | ||
| Analysis of peptide binding patterns in different major histocompatibility complex/T cell receptor complexes using pigeon cytochrome c-specific T cell hybridomas. Evidence that a single peptide binds major histocompatibility complex in different con | Q36356937 | ||
| Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling | Q36361605 | ||
| Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells | Q36361774 | ||
| Cellular and peptide requirements for in vitro clonal deletion of immature thymocytes | Q37217909 | ||
| Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex | Q37349445 | ||
| Developmental biology of T cells in T cell-receptor transgenic mice | Q37925543 | ||
| Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenics | Q38330987 | ||
| Specific low-affinity recognition of major histocompatibility complex plus peptide by soluble T-cell receptor | Q41628039 | ||
| Low Affinity Interaction of Peptide-MHC Complexes with T Cell Receptors | Q41652382 | ||
| Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cells | Q41807593 | ||
| Functionally distinct agretopic and epitopic sites. Analysis of the dominant T cell determinant of moth and pigeon cytochromes c with the use of synthetic peptide antigens | Q42074743 | ||
| A single stem cell can recolonize an embryonic thymus, producing phenotypically distinct T-cell populations | Q43526203 | ||
| Evidence for a differential avidity model of T cell selection in the thymus | Q45155438 | ||
| Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor | Q45986774 | ||
| Selection of amino acid sequences in the beta chain of the T cell antigen receptor | Q46159006 | ||
| Two signals are required for negative selection of CD4+CD8+ thymocytes | Q46168371 | ||
| T cell receptor junctional regions and the MHC molecule affect the recognition of antigenic peptides by T cell clones | Q46406255 | ||
| Monoclonal antibodies specific for rat IgG1, IgG2a, and IgG2b subclasses, and kappa chain monotypic and allotypic determinants: reagents for use with rat monoclonal antibodies. | Q52834062 | ||
| Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells | Q59078526 | ||
| Lower receptor avidity required for thymic clonal deletion than for effector T-cell function | Q59093837 | ||
| Effect of pH on MHC class II-peptide interactions | Q67728824 | ||
| Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition | Q67848563 | ||
| Heterodimeric, disulfide-linked alpha/beta T cell receptors in solution | Q68291793 | ||
| Inhibition of an allospecific T cell hybridoma by soluble class I proteins and peptides: estimation of the affinity of a T cell receptor for MHC | Q69735042 | ||
| Functional consequences of engagement of the T cell receptor by low affinity ligands | Q70522048 | ||
| The fine specificity of antigen and la determinant recognition by T cell hybridoma clones specific for pigeon cytochrome c | Q72678283 | ||
| Parallel cross-reactivity patterns of 2 sets of antigenically distinct cytochrome c peptides: possible evidence for a presentational model of Ir gene function | Q72912504 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | thymocyte | Q7799635 |
| P304 | page(s) | 4057-4061 | |
| P577 | publication date | 1994-04-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Negative selection of CD4+ CD8+ thymocytes by T-cell receptor peptide antagonists | |
| P478 | volume | 91 |
| Q71576582 | 3rd International Symposium on the Immunotherapy of the Rheumatic Diseases. 10-14 May 1995, Cyprus. Abstracts |
| Q46121537 | A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists |
| Q36369989 | A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex |
| Q77324273 | A very high level of crossreactivity is an essential feature of the T-cell receptor |
| Q33639952 | Affinity-based selection of regulatory T cells occurs independent of agonist-mediated induction of Foxp3 expression |
| Q36171567 | Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes |
| Q47846925 | Altered peptide ligands narrow the repertoire of cellular immune responses by interfering with T-cell priming |
| Q73270557 | Amelioration of relapsing experimental autoimmune encephalomyelitis with altered myelin basic protein peptides involves different cellular mechanisms |
| Q57209335 | Amino acid substitutions at position 97 in HLA-A2 segregate cytolysis from cytokine release in MART-1/Melan-A peptide AAGIGILTV-specific cytotoxic T lymphocytes |
| Q36402496 | An antagonist peptide mediates positive selection and CD4 lineage commitment of MHC class II-restricted T cells in the absence of CD4 |
| Q46532796 | CD4 augments the response of a T cell to agonist but not to antagonist ligands |
| Q36376237 | CD4(+) T cells from lupus-prone mice are hyperresponsive to T cell receptor engagement with low and high affinity peptide antigens: a model to explain spontaneous T cell activation in lupus |
| Q36960980 | Chimerism and tetragametic chimerism in humans: implications in autoimmunity, allorecognition and tolerance |
| Q35794602 | Defining the parameters necessary for T-cell recognition of ligands that vary in potency. |
| Q41722856 | Disruption of positive selection of thymocytes causes autoimmunity |
| Q34048781 | Dissociation of peripheral T cell responses from thymocyte negative selection by weak agonists supports a spare receptor model of T cell activation |
| Q77328529 | Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire |
| Q52045269 | Human leukocyte antigen phenotype imposes complex constraints on the antigen-specific cytotoxic T lymphocyte repertoire. |
| Q44066636 | Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation |
| Q52542067 | Induction of T-cell response to cryptic MHC determinants during allograft rejection. |
| Q36734207 | Inhibition of intrathymic T cell development by expression of a transgenic antagonist peptide |
| Q41225290 | Inhibition of thymocyte negative selection by T cell receptor antagonist peptides |
| Q34012661 | Interactions between double positive thymocytes and high affinity ligands presented by cortical epithelial cells generate double negative thymocytes with T cell regulatory activity |
| Q36096780 | Interactions with multiple peptide ligands determine the fate of developing thymocytes. |
| Q41881444 | Mature T cell reactivity altered by peptide agonist that induces positive selection |
| Q40653042 | Molecular mimicry: can epitope mimicry induce autoimmune disease? |
| Q24800305 | New approaches to eliciting protective immunity through T cell repertoire manipulation: the concept of thymic vaccination |
| Q38958324 | On Peptides and Altered Peptide Ligands: From Origin, Mode of Action and Design to Clinical Application (Immunotherapy). |
| Q73814851 | Peptide-induced T cell receptor down-regulation on naive T cells predicts agonist/partial agonist properties and strictly correlates with T cell activation |
| Q51103760 | Peptide-induced positive selection of TCR transgenic thymocytes in a coreceptor-independent manner. |
| Q36369555 | Positive selection of CD4(+) T cells is induced in vivo by agonist and inhibited by antagonist peptides |
| Q36380789 | Selection of antigen-specific T cells by a single IEk peptide combination |
| Q36367500 | Structural basis for T cell recognition of altered peptide ligands: a single T cell receptor can productively recognize a large continuum of related ligands |
| Q40653232 | Study of the Mechanism of TCR Antagonism Using Dual-TCR-Expressing T Cells |
| Q71548594 | T cell responses are governed by avidity and co-stimulatory thresholds |
| Q36401296 | The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes |
| Q37338505 | The role of CD4-Lck in T-cell receptor antagonism: evidence for negative signaling |
| Q36010523 | The role of peptides in thymic positive selection of class II major histocompatibility complex-restricted T cells |
| Q37051105 | Tuning of activation thresholds explains flexibility in the selection and development of T cells in the thymus |
| Q40922234 | Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation. |
| Q33987217 | Use of altered peptide ligands to modulate immune responses as a possible immunotherapy for allergies |
| Q41379043 | Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists |
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