| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.CELL.2011.06.004 |
| P953 | full work available online at | http://www.cell.com/article/S0092867411006465/pdf |
| https://api.elsevier.com/content/article/PII:S0092867411006465?httpAccept=text/plain | ||
| https://api.elsevier.com/content/article/PII:S0092867411006465?httpAccept=text/xml | ||
| https://doi.org/10.1016/j.cell.2011.06.004 | ||
| https://europepmc.org/articles/PMC3181170 | ||
| https://europepmc.org/articles/PMC3181170?pdf=render | ||
| P932 | PMC publication ID | 3181170 |
| P698 | PubMed publication ID | 21729785 |
| P5875 | ResearchGate publication ID | 51467874 |
| P2093 | author name string | Yoshihiro Matsumura | |
| Zhongying Yang | |||
| Brian Conti | |||
| Arthur E. Johnson | |||
| William R. Skach | |||
| Prasanna K. Devaraneni | |||
| P2860 | cites work | Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits | Q24300202 |
| Two translocating hydrophilic segments of a nascent chain span the ER membrane during multispanning protein topogenesis | Q24645170 | ||
| Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum | Q24673306 | ||
| Different conformations of nascent polypeptides during translocation across the ER membrane | Q24795321 | ||
| X-ray structure of a protein-conducting channel | Q27642744 | ||
| Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome | Q27658307 | ||
| Site-directed mutagenesis by overlap extension using the polymerase chain reaction | Q27860503 | ||
| Cellular mechanisms of membrane protein folding | Q33624056 | ||
| Evidence for the loop model of signal-sequence insertion into the endoplasmic reticulum | Q33655044 | ||
| The translocon: a dynamic gateway at the ER membrane | Q33804360 | ||
| The hydrophobic core of the Sec61 translocon defines the hydrophobicity threshold for membrane integration | Q33848740 | ||
| Fluorescence approaches for determining protein conformations, interactions and mechanisms at membranes | Q34464395 | ||
| Lipid-dependent membrane protein topogenesis | Q34550793 | ||
| Membrane-protein topology | Q34586351 | ||
| Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes | Q34719604 | ||
| Interactions between Sec complex and prepro-alpha-factor during posttranslational protein transport into the endoplasmic reticulum | Q34785303 | ||
| Molecular mechanism of signal sequence orientation in the endoplasmic reticulum | Q35160351 | ||
| From structure to disease: the evolving tale of aquaporin biology | Q35875999 | ||
| Topogenesis of membrane proteins at the endoplasmic reticulum | Q35906853 | ||
| Unassisted translocation of large polypeptide domains across phospholipid bilayers | Q36119397 | ||
| Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation | Q36321273 | ||
| Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY. | Q36321596 | ||
| Glycosylation can influence topogenesis of membrane proteins and reveals dynamic reorientation of nascent polypeptides within the translocon | Q36326048 | ||
| Substrate-specific regulation of the ribosome- translocon junction by N-terminal signal sequences | Q36525120 | ||
| A nascent membrane protein is located adjacent to ER membrane proteins throughout its integration and translation | Q36529324 | ||
| Sequence-specific retention and regulated integration of a nascent membrane protein by the endoplasmic reticulum Sec61 translocon | Q37061529 | ||
| Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle | Q37407450 | ||
| Transmembrane orientation of signal-anchor proteins is affected by the folding state but not the size of the N-terminal domain. | Q37626706 | ||
| Systematic probing of the environment of a translocating secretory protein during translocation through the ER membrane | Q40792995 | ||
| Construction of defined polytopic integral transmembrane proteins. The role of signal and stop transfer sequence permutations | Q41335669 | ||
| Environmental transition of signal-anchor sequences during membrane insertion via the endoplasmic reticulum translocon | Q42286958 | ||
| Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex | Q42770828 | ||
| Signal sequences control gating of the protein translocation channel in a substrate-specific manner | Q42818885 | ||
| A trans-membrane segment inside the ribosome exit tunnel triggers RAMP4 recruitment to the Sec61p translocase. | Q43092073 | ||
| Distinct biogenesis mechanisms for the water channels MIWC and CHIP28 at the endoplasmic reticulum | Q45155206 | ||
| The 70 carboxyl-terminal amino acids of nascent secretory proteins are protected from proteolysis by the ribosome and the protein translocation apparatus of the endoplasmic reticulum membrane. | Q45990533 | ||
| Sequence-specific alteration of the ribosome-membrane junction exposes nascent secretory proteins to the cytosol | Q46144128 | ||
| A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum | Q46562004 | ||
| Sequential triage of transmembrane segments by Sec61alpha during biogenesis of a native multispanning membrane protein | Q46722763 | ||
| Molecular code for transmembrane-helix recognition by the Sec61 translocon | Q46853934 | ||
| Identification of sequence determinants that direct different intracellular folding pathways for aquaporin-1 and aquaporin-4. | Q52540494 | ||
| Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore | Q54025256 | ||
| Cotranslational protein integration into the ER membrane is mediated by the binding of nascent chains to translocon proteins. | Q54517210 | ||
| The signal sequence moves through a ribosomal tunnel into a noncytoplasmic aqueous environment at the ER membrane early in translocation | Q70766402 | ||
| A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane | Q71939462 | ||
| Site-specific photocross-linking reveals that Sec61p and TRAM contact different regions of a membrane-inserted signal sequence | Q72639603 | ||
| Role of Sec61alpha in the regulated transfer of the ribosome-nascent chain complex from the signal recognition particle to the translocation channel | Q73453521 | ||
| Both Lumenal and Cytosolic Gating of the Aqueous ER Translocon Pore Are Regulated from Inside the Ribosome during Membrane Protein Integration | Q73526936 | ||
| Specific transmembrane segments are selectively delayed at the ER translocon during opsin biogenesis | Q80628282 | ||
| Secondary structure formation of a transmembrane segment in Kv channels | Q81818122 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | protein biosynthesis | Q211935 |
| P304 | page(s) | 134-147 | |
| P577 | publication date | 2011-07-01 | |
| 2011-07-08 | |||
| P1433 | published in | Cell | Q655814 |
| P1476 | title | Stepwise insertion and inversion of a type II signal anchor sequence in the ribosome-Sec61 translocon complex | |
| Stepwise Insertion and Inversion of a Type II Signal Anchor Sequence in the Ribosome-Sec61 Translocon Complex | |||
| P478 | volume | 146 |
| Q91826480 | A Shared Mechanism for the Folding of Voltage-Gated K+ Channels |
| Q34170244 | A flip turn for membrane protein insertion |
| Q38077207 | Adaptation of low-resolution methods for the study of yeast microsomal polytopic membrane proteins: a methodological review. |
| Q47096501 | An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases. |
| Q37552363 | An allosteric Sec61 inhibitor traps nascent transmembrane helices at the lateral gate |
| Q98733438 | CFTR trafficking mutations disrupt cotranslational protein folding by targeting biosynthetic intermediates |
| Q96135848 | Cell-free expression tools to study co-translational folding of alpha helical membrane transporters |
| Q28078736 | Co- and Post-Translational Protein Folding in the ER |
| Q42261006 | Co-translational processing of glycoprotein 3 from equine arteritis virus: N-glycosylation adjacent to the signal peptide prevents cleavage. |
| Q35153371 | Cotranslational folding inhibits translocation from within the ribosome-Sec61 translocon complex |
| Q35470364 | Cotranslational stabilization of Sec62/63 within the ER Sec61 translocon is controlled by distinct substrate-driven translocation events |
| Q36158643 | Determining the N-terminal orientations of recombinant transmembrane proteins in the Escherichia coli plasma membrane |
| Q24306519 | Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells |
| Q36200511 | Direct simulation of early-stage Sec-facilitated protein translocation |
| Q90044373 | Dynamics of Co-translational Membrane Protein Integration and Translocation via the Sec Translocon |
| Q36948835 | Evolutionary well-conserved region in the signal peptide of parathyroid hormone-related protein is critical for its dual localization through the regulation of ER translocation |
| Q36535313 | Exploring the nature of the translocon-assisted protein insertion |
| Q92651089 | Functions and Mechanisms of the Human Ribosome-Translocon Complex |
| Q47228430 | Inhibitors of protein translocation across membranes of the secretory pathway: novel antimicrobial and anticancer agents. |
| Q36346841 | Intra-plastid protein trafficking: How plant cells adapted prokaryotic mechanisms to the eukaryotic condition |
| Q91787179 | Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation |
| Q30155421 | Kinetic Analysis of Ribosome-bound Fluorescent Proteins Reveals an Early, Stable, Cotranslational Folding Intermediate |
| Q36355150 | Long-Timescale Dynamics and Regulation of Sec-Facilitated Protein Translocation |
| Q37973762 | Mechanisms of Sec61/SecY-Mediated Protein Translocation Across Membranes |
| Q41217184 | Membrane protein TM segments are retained at the translocon during integration until the nascent chain cues FRET-detected release into bulk lipid |
| Q27937505 | Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes |
| Q38951193 | Mycolactone reveals the substrate-driven complexity of Sec61-dependent transmembrane protein biogenesis. |
| Q47234530 | Plastid ribosome pausing is induced by multiple features and is linked to protein complex assembly |
| Q35276847 | Polytopic membrane protein folding at L17 in the ribosome tunnel initiates cyclical changes at the translocon |
| Q39472094 | Positional editing of transmembrane domains during ion channel assembly |
| Q43093001 | Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling |
| Q38682991 | Refined topology model of the STT3/Stt3 protein subunit of the oligosaccharyltransferase complex |
| Q37163477 | Regional discrimination and propagation of local rearrangements along the ribosomal exit tunnel |
| Q36255160 | Regulation of multispanning membrane protein topology via post-translational annealing |
| Q37502171 | Reorientation of the first signal-anchor sequence during potassium channel biogenesis at the Sec61 complex. |
| Q36947743 | Sec62 Protein Mediates Membrane Insertion and Orientation of Moderately Hydrophobic Signal Anchor Proteins in the Endoplasmic Reticulum (ER) |
| Q28542401 | Signal peptide-binding drug as a selective inhibitor of co-translational protein translocation |
| Q44540523 | Stop-and-Move of a Marginally Hydrophobic Segment Translocating across the Endoplasmic Reticulum Membrane |
| Q36318227 | Structurally detailed coarse-grained model for Sec-facilitated co-translational protein translocation and membrane integration |
| Q89513070 | TRAM1 protein may support ER protein import by modulating the phospholipid bilayer near the lateral gate of the Sec61-channel |
| Q45205207 | Tail-extension following the termination codon is critical for release of the nascent chain from membrane-bound ribosomes in a reticulocyte lysate cell-free system |
| Q36323490 | The Ribosome-Sec61 Translocon Complex Forms a Cytosolically Restricted Environment for Early Polytopic Membrane Protein Folding |
| Q90391222 | The molecular mechanism of cotranslational membrane protein recognition and targeting by SecA |
| Q38270911 | The safety dance: biophysics of membrane protein folding and misfolding in a cellular context |
| Q90627522 | The signal peptide as a new target for drug design |
| Q64226641 | The signal peptide plus a cluster of positive charges in prion protein dictate chaperone-mediated Sec61 channel gating |
| Q35276891 | Transmembrane segments of nascent polytopic membrane proteins control cytosol/ER targeting during membrane integration |
| Q38786622 | Tuning Side Arm Electronics in Unsymmetrical Cyclotriazadisulfonamide (CADA) Endoplasmic Reticulum (ER) Translocation Inhibitors to Improve their Human Cluster of Differentiation 4 (CD4) Receptor Down-Modulating Potencies. |
| Q54326413 | Two-step insertion at the SecY translocon |
| Q34428674 | Type II transmembrane domain hydrophobicity dictates the cotranslational dependence for inversion. |
| Q36570393 | Understanding integration of α-helical membrane proteins: the next steps |
| Q27690670 | Visualization of a polytopic membrane protein during SecY-mediated membrane insertion |
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