| scholarly article | Q13442814 |
| P50 | author | Michael McKenna | Q56435901 |
| Rachel E Simmonds | Q50419452 | ||
| Stephen High | Q30510387 | ||
| P2093 | author name string | Michael McKenna | |
| Rachel E Simmonds | |||
| P2860 | cites work | Transport route for synaptobrevin via a novel pathway of insertion into the endoplasmic reticulum membrane | Q24568369 |
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| Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma | Q24681545 | ||
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| Inhibitors of Protein Translocation Across the ER Membrane | Q27021065 | ||
| Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions | Q27318699 | ||
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| The protein-conducting channel in the membrane of the endoplasmic reticulum is open laterally toward the lipid bilayer | Q54011077 | ||
| Orientation of Internal Signal-Anchor Sequences at the Sec61 Translocon | Q56775230 | ||
| Towards a comparative anatomy of N-terminal topogenic protein sequences | Q57381689 | ||
| Biogenesis of Polytopic Membrane Proteins: Membrane Segments of P-glycoprotein Sequentially Translocate To Span the ER Membrane† | Q62108911 | ||
| The Sec61 complex is essential for the insertion of proteins into the membrane of the endoplasmic reticulum | Q72165273 | ||
| The thiol-dependent reductase ERp57 interacts specifically with N-glycosylated integral membrane proteins | Q73343307 | ||
| Total synthesis of the mycolactones | Q77636654 | ||
| The translocation inhibitor CAM741 interferes with vascular cell adhesion molecule 1 signal peptide insertion at the translocon | Q40242713 | ||
| Systematic probing of the environment of a translocating secretory protein during translocation through the ER membrane | Q40792995 | ||
| Mechanistic insights into the inhibition of Sec61-dependent co- and post-translational translocation by mycolactone. | Q40794641 | ||
| The inhibitory action of Mycobacterium ulcerans soluble factor on monocyte/T cell cytokine production and NF-kappa B function | Q40797227 | ||
| Domain structure of synaptotagmin (p65) | Q42626376 | ||
| Sec61p is adjacent to nascent type I and type II signal-anchor proteins during their membrane insertion. | Q42770139 | ||
| Human erythrocyte membrane sialoglycoprotein beta. The cDNA sequence suggests the absence of a cleaved N-terminal signal sequence | Q42855791 | ||
| Mycolactone suppresses T cell responsiveness by altering both early signaling and posttranslational events | Q43204610 | ||
| Mycolactone inhibits monocyte cytokine production by a posttranscriptional mechanism. | Q46129062 | ||
| A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum | Q46562004 | ||
| Molecular code for transmembrane-helix recognition by the Sec61 translocon | Q46853934 | ||
| Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel | Q46869479 | ||
| Relation between aminoacyl-tRNA stability and the fixed amino acid | Q53794502 | ||
| Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion | Q27689043 | ||
| A structural ensemble of a ribosome-nascent chain complex during cotranslational protein folding | Q27704200 | ||
| Selective inhibition of cotranslational translocation of vascular cell adhesion molecule 1 | Q28261510 | ||
| Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence | Q28296388 | ||
| The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER | Q28541949 | ||
| A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation | Q28568867 | ||
| Signal sequences. The limits of variation | Q29616543 | ||
| Structure of the native Sec61 protein-conducting channel | Q30667297 | ||
| Pathogenetic mechanisms of the intracellular parasite Mycobacterium ulcerans leading to Buruli ulcer | Q33511900 | ||
| Evidence for the loop model of signal-sequence insertion into the endoplasmic reticulum | Q33655044 | ||
| Topogenesis of membrane proteins: determinants and dynamics. | Q34353219 | ||
| The signal sequence influences post-translational ER translocation at distinct stages | Q35018270 | ||
| Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon | Q35178294 | ||
| Asn- and Asp-mediated interactions between transmembrane helices during translocon-mediated membrane protein assembly | Q35191191 | ||
| Stepwise Insertion and Inversion of a Type II Signal Anchor Sequence in the Ribosome-Sec61 Translocon Complex | Q35235093 | ||
| Mechanisms that determine the transmembrane disposition of proteins | Q35455119 | ||
| Mycolactone-mediated inhibition of tumor necrosis factor production by macrophages infected with Mycobacterium ulcerans has implications for the control of infection | Q35949741 | ||
| Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor | Q36209511 | ||
| Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone | Q36229394 | ||
| TRC40 can deliver short secretory proteins to the Sec61 translocon | Q36242781 | ||
| Multiple determinants direct the orientation of signal-anchor proteins: the topogenic role of the hydrophobic signal domain | Q36274131 | ||
| A gating motif in the translocation channel sets the hydrophobicity threshold for signal sequence function | Q36455908 | ||
| Sequence-specific retention and regulated integration of a nascent membrane protein by the endoplasmic reticulum Sec61 translocon | Q37061529 | ||
| Secretory protein profiling reveals TNF-α inactivation by selective and promiscuous Sec61 modulators | Q37374069 | ||
| Delivering proteins for export from the cytosol | Q37420386 | ||
| Transcription of full-length and truncated mRNA transcripts to study protein translocation across the endoplasmic reticulum | Q37479652 | ||
| Mycolactone subverts immunity by selectively blocking the Sec61 translocon. | Q37500335 | ||
| An allosteric Sec61 inhibitor traps nascent transmembrane helices at the lateral gate | Q37552363 | ||
| Buruli Ulcer: Advances in Understanding Mycobacterium ulcerans Infection | Q37811544 | ||
| Pleiotropic molecular effects of the Mycobacterium ulcerans virulence factor mycolactone underlying the cell death and immunosuppression seen in Buruli ulcer | Q38180777 | ||
| Mechanism of protein translocation across the endoplasmic reticulum membrane | Q39507809 | ||
| Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum | Q39776644 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | transmembrane protein | Q424204 |
| P304 | page(s) | 1307-1320 | |
| P577 | publication date | 2017-02-20 | |
| P1433 | published in | Journal of Cell Science | Q1524177 |
| P1476 | title | Mycolactone reveals the substrate-driven complexity of Sec61-dependent transmembrane protein biogenesis | |
| P478 | volume | 130 |
| Q47096501 | An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases. |
| Q59800191 | EMC Is Required to Initiate Accurate Membrane Protein Topogenesis |
| Q92651089 | Functions and Mechanisms of the Human Ribosome-Translocon Complex |
| Q53702000 | Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4. |
| Q91787179 | Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation |
| Q57776721 | Modular total syntheses of mycolactone A/B and its [2H]-isotopologue |
| Q47108141 | Multiple pathways facilitate the biogenesis of mammalian tail-anchored proteins |
| Q58042832 | Proteomics Reveals Scope of Mycolactone-mediated Sec61 Blockade and Distinctive Stress Signature |
| Q51410365 | Regulation of the Cell Biology of Antigen Cross-Presentation. |
| Q38692382 | Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export |
| Q57776726 | Synthetic strategies towards mycolactone A/B, an exotoxin secreted by Mycobacterium ulcerans |
| Q48269589 | The potent effect of mycolactone on lipid membranes. |
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