Effects of UMB24 and (+/-)-SM 21, putative sigma2-preferring antagonists, on behavioral toxic and stimulant effects of cocaine in mice

scientific article published on 22 December 2006

Effects of UMB24 and (+/-)-SM 21, putative sigma2-preferring antagonists, on behavioral toxic and stimulant effects of cocaine in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.PBB.2006.12.011
P932PMC publication ID1892169
P698PubMed publication ID17241657
P5875ResearchGate publication ID6560762

P2093author name stringRae R Matsumoto
Andrew Coop
Buddy Pouw
Aisha L Mack
Antawan Daniels
P2860cites workRimcazole analogs attenuate the convulsive effects of cocaine: correlation with binding to sigma receptors rather than dopamine transportersQ28202676
Sigma receptors: potential medications development target for anti-cocaine agentsQ28208121
Involvement of sigma receptors in the behavioral effects of cocaine: evidence from novel ligands and antisense oligodeoxynucleotidesQ28215345
Sigma receptors: biology and therapeutic potentialQ28266963
The analgesic tropane analogue (+/-)-SM 21 has a high affinity for sigma2 receptorsQ28372452
Two novel sigma receptor ligands, BD1047 and LR172, attenuate cocaine-induced toxicity and locomotor activityQ28376445
Sigma-2 receptors are specifically localized to lipid rafts in rat liver membranesQ34326129
Cocaine, reward, movement and monoamine transportersQ34502175
Cocaine binding at sigma receptors.Q34555132
Sigma(1) (sigma(1)) receptor antagonists represent a new strategy against cocaine addiction and toxicityQ34804462
Antisense oligodeoxynucleotide reduces brain dopamine D2 receptors: behavioral correlatesQ38315024
Cocaine-induced convulsions: pharmacological antagonism at serotonergic, muscarinic and sigma receptorsQ42550669
Characterization of two novel sigma receptor ligands: antidystonic effects in rats suggest sigma receptor antagonismQ42557456
(+/-)-SM 21 attenuates the convulsive and locomotor stimulatory effects of cocaine in miceQ43574377
Novel spiropiperidines as highly potent and subtype selective sigma-receptor ligands. Part 1.Q43849727
N-arylalkylpiperidines as high-affinity sigma-1 and sigma-2 receptor ligands: phenylpropylamines as potential leads for selective sigma-2 agentsQ43869049
sigma(2) Receptors regulate changes in sphingolipid levels in breast tumor cellsQ44014688
Synthesis of N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl carbamate analogs as sigma2 receptor ligandsQ46156850
Ibogaine and its congeners are sigma 2 receptor-selective ligands with moderate affinityQ46323624
Synthesis and in vivo evaluation of a new PET radioligand for studying sigma-2 receptorsQ46465098
CB-64D and CB-184: ligands with high σ2 receptor affinity and subtype selectivityQ46698599
(E)-8-benzylidene derivatives of 2-methyl-5-(3-hydroxyphenyl)morphans: highly selective ligands for the sigma 2 receptor subtypeQ46912350
[3H]1,3-di(2-tolyl)guanidine and [3H](+)pentazocine binding sites in the rat brain: autoradiographic visualization of the putative sigma1 and sigma2 receptor subtypesQ48818603
Pharmacological identification of SM-21, the novel sigma(2) antagonistQ49059458
Secondary amine analogues of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters.Q51636071
Inotropic action of sigma receptor ligands in isolated cardiac myocytes from adult ratsQ70911420
Ibogaine possesses a selective affinity for σ2 receptorsQ71852379
Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 1. 3-(omega-aminoalkyl)-1H-indolesQ72317740
A comparison of (-)-deoxybenzomorphans devoid of opiate activity with their dextrorotatory phenolic counterparts suggests role of sigma 2 receptors in motor functionQ72954030
Modulation of cellular calcium by sigma-2 receptors: release from intracellular stores in human SK-N-SH neuroblastoma cellsQ73478851
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)86-91
P577publication date2006-12-22
P1433published inPharmacology, Biochemistry and BehaviorQ15716554
P1476titleEffects of UMB24 and (+/-)-SM 21, putative sigma2-preferring antagonists, on behavioral toxic and stimulant effects of cocaine in mice
P478volume86

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cites work (P2860)
Q392978892-Aminopyridine derivatives as potential σ(2) receptor antagonists
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Q34383909Chlorophenylpiperazine analogues as high affinity dopamine transporter ligands.
Q50323703Cocaine Effects on Dopaminergic Transmission Depend on a Balance between Sigma-1 and Sigma-2 Receptor Expression
Q36494168Cocaine occupancy of sigma1 receptors and dopamine transporters in mice
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Q36793936Nitrile analogs of meperidine as high affinity and selective sigma-1 receptor ligands
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Q37545379Pharmacology and therapeutic potential of sigma(1) receptor ligands
Q37357475Selective reduction of alcohol drinking in Sardinian alcohol-preferring rats by a sigma-1 receptor antagonist
Q39185737Sigma Receptors and Substance Use Disorders
Q33613556Sigma-1 receptors regulate Bcl-2 expression by reactive oxygen species-dependent transcriptional regulation of nuclear factor kappaB
Q34362333Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.
Q24615155Sigma1 receptor antagonists determine the behavioral pattern of the methamphetamine-induced stereotypy in mice
Q88574251Small molecule modulators of σ2R/Tmem97 reduce alcohol withdrawal-induced behaviors
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Q24622567Targeting sigma receptors: novel medication development for drug abuse and addiction
Q36107398The effect of the pyridyl nitrogen position in pyridylpiperazine sigma ligands
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Q24658287The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking

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