scholarly article | Q13442814 |
P50 | author | Richard P. Harvey | Q24067156 |
P2093 | author name string | Jun Wang | |
Chao Liu | |||
Cheng Sun | |||
Yanding Zhang | |||
YiPing Chen | |||
Fen Wang | |||
James F Martin | |||
Diankun Yu | |||
Fading Chen | |||
Laura Schrader | |||
Wenduo Ye | |||
Yingnan Song | |||
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An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation | Q27863351 | ||
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Shox2 is required for chondrocyte proliferation and maturation in proximal limb skeleton | Q28505826 | ||
Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development | Q28506813 | ||
Shox2-deficient mice exhibit a rare type of incomplete clefting of the secondary palate | Q28506891 | ||
The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system | Q28507264 | ||
Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation | Q28509085 | ||
Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis | Q28586231 | ||
Shox2 function couples neural, muscular and skeletal development in the proximal forelimb | Q28586634 | ||
A mouse model for human short-stature syndromes identifies Shox2 as an upstream regulator of Runx2 during long-bone development | Q28588258 | ||
Pitx2c and Nkx2-5 are required for the formation and identity of the pulmonary myocardium | Q28589895 | ||
Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice | Q28592303 | ||
Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3 | Q28594589 | ||
Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins | Q29620720 | ||
HCN4 dynamically marks the first heart field and conduction system precursors | Q33598169 | ||
Extended atrial conduction system characterised by the expression of the HCN4 channel and connexin45 | Q59594754 | ||
Dependence on the transcription factor Shox2 for specification of sensory neurons conveying discriminative touch | Q60694979 | ||
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Development of the pulmonary vein and the systemic venous sinus: an interactive 3D overview | Q33968240 | ||
Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification | Q34006337 | ||
Baf250a orchestrates an epigenetic pathway to repress the Nkx2.5-directed contractile cardiomyocyte program in the sinoatrial node | Q34289875 | ||
Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3 | Q34341676 | ||
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Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart. | Q34805195 | ||
The Electrophysiological Organization of the Embryonic Chick Heart | Q36374826 | ||
Fibroblast growth factor 10 gene regulation in the second heart field by Tbx1, Nkx2-5, and Islet1 reveals a genetic switch for down-regulation in the myocardium. | Q36389611 | ||
Spatiotemporal regulation of an Hcn4 enhancer defines a role for Mef2c and HDACs in cardiac electrical patterning | Q36433714 | ||
The heart-forming fields: one or multiple? | Q36854392 | ||
Prevalence and spectrum of Nkx2.5 mutations associated with idiopathic atrial fibrillation | Q36906864 | ||
Nkx2-5 mediates differential cardiac differentiation through interaction with Hoxa10. | Q37025687 | ||
Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor | Q37135357 | ||
Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5. | Q37222054 | ||
Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers | Q37403084 | ||
The anatomy of the coronary sinus venous system for the cardiac electrophysiologist | Q37622589 | ||
Development of the pacemaker tissues of the heart. | Q37687712 | ||
A spatiotemporal evaluation of the contribution of the dorsal mesenchymal protrusion to cardiac development | Q37730021 | ||
Normal and abnormal development of pulmonary veins: State of the art and correlation with clinical entities | Q37776810 | ||
Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer | Q38324392 | ||
Pitx2 confers left morphological, molecular, and functional identity to the sinus venosus myocardium | Q40412634 | ||
Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia | Q41136701 | ||
Generation of Shox2-Cre allele for tissue specific manipulation of genes in the developing heart, palate, and limb | Q41773233 | ||
Locomotor rhythm generation linked to the output of spinal shox2 excitatory interneurons | Q42253746 | ||
Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart | Q42382110 | ||
A novel PITX2c loss-of-function mutation associated with familial atrial fibrillation | Q44880531 | ||
A novel NKX2.5 loss-of-function mutation responsible for familial atrial fibrillation | Q45022910 | ||
The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field | Q46196456 | ||
Comparative transgenic analysis of enhancers from the human SHOX and mouse Shox2 genomic regions | Q47768125 | ||
Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome | Q47955346 | ||
Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing. | Q50792328 | ||
Nkx2.5-negative myocardium of the posterior heart field and its correlation with podoplanin expression in cells from the developing cardiac pacemaking and conduction system. | Q51988770 | ||
Embryonic conduction tissue: a spatial correlation with adult arrhythmogenic areas. | Q52001186 | ||
Embryonic expression of an Nkx2-5/Cre gene using ROSA26 reporter mice. | Q52125445 | ||
HNK-1 expression patterns in the embryonic rat heart distinguish between sinuatrial tissues and atrial myocardium. | Q52172317 | ||
Efficient Cre-mediated deletion in cardiac progenitor cells conferred by a 3'UTR-ires-Cre allele of the homeobox gene Nkx2-5. | Q53963814 | ||
Formation of the Venous Pole of the Heart From an Nkx2-5-Negative Precursor Population Requires Tbx18 | Q56000972 | ||
Organisation of the mouse sinoatrial node: structure and expression of HCN channels | Q59594730 | ||
P433 | issue | 14 | |
P407 | language of work or name | English | Q1860 |
P1104 | number of pages | 12 | |
P304 | page(s) | 2521-2532 | |
P577 | publication date | 2015-07-02 | |
P1433 | published in | Development | Q3025404 |
P1476 | title | A common Shox2-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node | |
P478 | volume | 142 |
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Q37120535 | A unique stylopod patterning mechanism by Shox2-controlled osteogenesis. |
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Q36859198 | Coding and non-coding variants in the SHOX2 gene in patients with early-onset atrial fibrillation |
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Q89661624 | Comparative study of hyperpolarization-activated currents in pulmonary vein cardiomyocytes isolated from rat, guinea pig, and rabbit |
Q97597497 | Conjugated activation of myocardial-specific transcription of Gja5 by a pair of Nkx2-5-Shox2 co-responsive elements |
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Q90461383 | Differences in Expression of Genes Involved in Bone Development and Morphogenesis in the Walls of Internal Thoracic Artery and Saphenous Vein Conduits May Provide Markers Useful for Evaluation Graft Patency |
Q47727535 | FGF8 Signaling Alters the Osteogenic Cell Fate in the Hard Palate |
Q92240317 | Functional Characterization of Rare Variants in the SHOX2 Gene Identified in Sinus Node Dysfunction and Atrial Fibrillation |
Q38431067 | Gene Expression Networks in the Murine Pulmonary Myocardium Provide Insight into the Pathobiology of Atrial Fibrillation |
Q36372470 | Genetic Regulation of Sinoatrial Node Development and Pacemaker Program in the Venous Pole |
Q91970903 | Geometrical Patterning and Constituent Cell Heterogeneity Facilitate Electrical Conduction Disturbances in a Human Induced Pluripotent Stem Cell-Based Platform: An In vitro Disease Model of Atrial Arrhythmias |
Q88651515 | Interplay between cardiac transcription factors and non-coding RNAs in predisposing to atrial fibrillation |
Q47841255 | Mutations in Hnrnpa1 cause congenital heart defects |
Q38649331 | New Approaches to Biological Pacemakers: Links to Sinoatrial Node Development |
Q91671527 | Nkx2.5 insufficiency leads to atrial electrical remodeling through Wnt signaling in HL-1 cells |
Q48172096 | On the Evolution of the Cardiac Pacemaker |
Q99721471 | Precise Correction of Heterozygous SHOX2 Mutations in hiPSCs Derived from Patients with Atrial Fibrillation via Genome Editing and Sib Selection |
Q50130661 | RHOA-ROCK signalling is necessary for lateralization and differentiation of the developing sinoatrial node |
Q48106167 | Spatially resolved RNA-sequencing of the embryonic heart identifies a role for Wnt/β-catenin signaling in autonomic control of heart rate. |
Q38920721 | Spatiotemporal regulation of enhancers during cardiogenesis |
Q90748209 | The Joint Analysis of Multi-Omics Data Revealed the Methylation-Expression Regulations in Atrial Fibrillation |
Q26770904 | The formation and function of the cardiac conduction system |
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Q38695345 | Transient Notch Activation Induces Long-Term Gene Expression Changes Leading to Sick Sinus Syndrome in Mice |
Q48183264 | nkx genes establish SHF cardiomyocyte progenitors at the arterial pole and pattern the venous pole through Isl1 repression. |
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