scholarly article | Q13442814 |
P819 | ADS bibcode | 2007PNAS..10412726M |
P356 | DOI | 10.1073/PNAS.0608451104 |
P932 | PMC publication ID | 1931564 |
P698 | PubMed publication ID | 17652177 |
P5875 | ResearchGate publication ID | 6186940 |
P50 | author | Gábor Balázsi | Q56223763 |
P2093 | author name string | James J Collins | |
Kevin F Murphy | |||
P2860 | cites work | Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion | Q24535235 |
Synthetic biology: new engineering rules for an emerging discipline | Q24672399 | ||
Noise minimization in eukaryotic gene expression | Q24792798 | ||
Transcriptional pulsing of a developmental gene | Q27317160 | ||
Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure | Q28131658 | ||
Stochastic gene expression in a single cell | Q28131784 | ||
Construction of a genetic toggle switch in Escherichia coli | Q28144086 | ||
Identifying regulatory networks by combinatorial analysis of promoter elements | Q28215713 | ||
Engineered riboregulators enable post-transcriptional control of gene expression | Q28267834 | ||
Diversity in times of adversity: probabilistic strategies in microbial survival games | Q29039603 | ||
A synthetic oscillatory network of transcriptional regulators | Q29547344 | ||
Engineering stability in gene networks by autoregulation | Q29615326 | ||
Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise | Q29615953 | ||
Gene regulation at the single-cell level | Q29615954 | ||
Control of stochasticity in eukaryotic gene expression | Q29615955 | ||
Intrinsic and extrinsic contributions to stochasticity in gene expression | Q29615956 | ||
Regulation of noise in the expression of a single gene | Q29616626 | ||
Stochasticity in gene expression: from theories to phenotypes | Q29617360 | ||
Noise in eukaryotic gene expression | Q29617406 | ||
Stochastic mechanisms in gene expression | Q29617407 | ||
Foundations for engineering biology | Q30482962 | ||
Spatiotemporal control of gene expression with pulse-generating networks. | Q30579452 | ||
Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity | Q33220546 | ||
Fundamentally different logic of gene regulation in eukaryotes and prokaryotes | Q33691046 | ||
On schemes of combinatorial transcription logic | Q33711386 | ||
Inference of combinatorial regulation in yeast transcriptional networks: a case study of sporulation | Q33836225 | ||
Topological units of environmental signal processing in the transcriptional regulatory network of Escherichia coli. | Q33841134 | ||
Hysteresis in a synthetic mammalian gene network | Q33892242 | ||
Ultrasensitivity and noise propagation in a synthetic transcriptional cascade. | Q33926820 | ||
Negative autoregulation speeds the response times of transcription networks | Q33962256 | ||
Modulation of myosin A expression by a newly established tetracycline repressor-based inducible system in Toxoplasma gondii | Q33988702 | ||
Summing up the noise in gene networks | Q34293479 | ||
Programmable cells: interfacing natural and engineered gene networks | Q34322635 | ||
Noise propagation in gene networks | Q34406341 | ||
Enhancement of cellular memory by reducing stochastic transitions | Q34418258 | ||
Contributions of low molecule number and chromosomal positioning to stochastic gene expression | Q34441114 | ||
A system of counteracting feedback loops regulates Cdc42p activity during spontaneous cell polarization | Q34455822 | ||
Real-time kinetics of gene activity in individual bacteria | Q34477297 | ||
Noise in protein expression scales with natural protein abundance | Q34528937 | ||
Gal80-Gal80 interaction on adjacent Gal4p binding sites is required for complete GAL gene repression | Q34582719 | ||
Phenotypic consequences of promoter-mediated transcriptional noise | Q34594662 | ||
Demand Theory of Gene Regulation. I. Quantitative Development of the Theory | Q34605049 | ||
Stochastic gene expression in fluctuating environments | Q34644561 | ||
Engineered gene circuits. | Q34997456 | ||
Control, exploitation and tolerance of intracellular noise | Q34997459 | ||
Detailed map of a cis-regulatory input function | Q35146579 | ||
Prediction and measurement of an autoregulatory genetic module | Q35146614 | ||
Gene regulation by tetracyclines. Constraints of resistance regulation in bacteria shape TetR for application in eukaryotes | Q35180176 | ||
Advances in synthetic biology: on the path from prototypes to applications | Q36194341 | ||
RNA synthetic biology | Q36470934 | ||
Modular approaches to expanding the functions of living matter | Q36482527 | ||
Tetracycline-controlled gene expression in Entamoeba histolytica | Q39042618 | ||
Transcription reinitiation rate: a potential role for TATA box stabilization of the TFIID:TFIIA:DNA complex | Q39727107 | ||
Computer simulations and experimental studies of gel mobility patterns for weak and strong non-cooperative protein binding to two targets on the same DNA: application to binding of tet repressor variants to multiple and single tet operator sites | Q40531842 | ||
Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements | Q40715002 | ||
Quantitative analysis of ultrasensitive responses | Q42482603 | ||
Regulation of transcription: from lambda to eukaryotes | Q43979454 | ||
Development of genetic circuitry exhibiting toggle switch or oscillatory behavior in Escherichia coli | Q44465976 | ||
A stochastic model for gene induction. | Q44758737 | ||
Multistability in the lactose utilization network of Escherichia coli | Q44770275 | ||
An engineered epigenetic transgene switch in mammalian cells | Q44927488 | ||
Genomic Cis-Regulatory Logic: Experimental and Computational Analysis of a Sea Urchin Gene | Q46041940 | ||
Origins of extrinsic variability in eukaryotic gene expression | Q46189027 | ||
A synthetic gene-metabolic oscillator. | Q46366557 | ||
A bottom-up approach to gene regulation. | Q46947473 | ||
From specific gene regulation to genomic networks: a global analysis of transcriptional regulation in Escherichia coli | Q47817916 | ||
Programmed population control by cell-cell communication and regulated killing | Q51693435 | ||
From molecular noise to behavioural variability in a single bacterium | Q52000300 | ||
Observing conformational and activity changes of tet repressor in vivo | Q54045650 | ||
The Tn10-encoded Tet repressor blocks early but not late steps of assembly of the RNA polymerase II initiation complex in vivo | Q54275360 | ||
Regulated expression of heterologous genes in Bacillus subtilis using the Tn10 encoded tet regulatory elements | Q54317609 | ||
Exact stochastic simulation of coupled chemical reactions | Q56536017 | ||
Evidence for two modes of cooperative DNA binding in vivo that do not involve direct protein-protein interactions | Q74460820 | ||
P433 | issue | 31 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 12726-12731 | |
P577 | publication date | 2007-07-24 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Combinatorial promoter design for engineering noisy gene expression | |
P478 | volume | 104 |
Q57072821 | A Promoter Variant Confers Constitutive Noisy Bimodal Expression That Increases Oxidative Stress Resistance in Yeast |
Q51067540 | A Synthetic Hybrid Promoter for Xylose-Regulated Control of Gene Expression in Saccharomyces Yeasts |
Q35672592 | A common repressor pool results in indeterminacy of extrinsic noise |
Q35101641 | A computational pipeline for identifying kinetic motifs to aid in the design and improvement of synthetic gene circuits |
Q33803232 | A novel sequence and context based method for promoter recognition |
Q42102488 | A regulatory role for repeated decoy transcription factor binding sites in target gene expression |
Q34292208 | A synthetic biology framework for programming eukaryotic transcription functions. |
Q33651972 | An evolutionarily biased distribution of miRNA sites toward regulatory genes with high promoter-driven intrinsic transcriptional noise |
Q33386730 | Analysis of combinatorial cis-regulation in synthetic and genomic promoters |
Q42637452 | Antagonism between binding site affinity and conformational dynamics tunes alternative cis-interactions within Shp2 |
Q53514546 | Bacterial XylRs and synthetic promoters function as genetically encoded xylose biosensors in Saccharomyces cerevisiae |
Q47347523 | Beyond initiation-limited translational bursting: the effects of burst size distributions on the stability of gene expression |
Q42114903 | Bistability in feedback circuits as a byproduct of evolution of evolvability |
Q40957421 | Blue light-mediated transcriptional activation and repression of gene expression in bacteria |
Q36813712 | Build to understand: synthetic approaches to biology |
Q35883432 | Combinatorial optimization of CO2 transport and fixation to improve succinate production by promoter engineering |
Q35581566 | Compensation for differences in gene copy number among yeast ribosomal proteins is encoded within their promoters |
Q34002167 | Computational design of synthetic regulatory networks from a genetic library to characterize the designability of dynamical behaviors |
Q52642701 | Construction of hybrid regulated mother-specific yeast promoters for inducible differential gene expression |
Q37981787 | Construction of synthetic regulatory networks in yeast. |
Q37330227 | Control and signal processing by transcriptional interference. |
Q34260738 | Controlling promoter strength and regulation in Saccharomyces cerevisiae using synthetic hybrid promoters |
Q28484944 | Design Principles of a Genetic Alarm Clock |
Q35212025 | Design and characterization of a dual-mode promoter with activation and repression capability for tuning gene expression in yeast |
Q50965993 | Design and engineering of intracellular-metabolite-sensing/regulation gene circuits in Saccharomyces cerevisiae |
Q30703913 | Discrimination between thermodynamic models of cis-regulation using transcription factor occupancy data |
Q28732365 | Distance and helical phase dependence of synergistic transcription activation in cis-regulatory module |
Q33431823 | Diversity-based, model-guided construction of synthetic gene networks with predicted functions |
Q36938643 | Dynamical analysis on gene activity in the presence of repressors and an interfering promoter |
Q28477325 | Effect of promoter architecture on the cell-to-cell variability in gene expression |
Q47107934 | Efflux Pump Control Alters Synthetic Gene Circuit Function. |
Q37328414 | Engineering prokaryotic gene circuits |
Q35597773 | Expression-level dependent perturbation of cell proteostasis and nuclear morphology by aggregation-prone polyglutamine proteins. |
Q91869645 | Fine-tuning of noise in gene expression with nucleosome remodeling |
Q58733567 | Fitness effects of altering gene expression noise in |
Q35081702 | Fundamental relationship between operon organization and gene expression |
Q93162445 | Gene networks that compensate for crosstalk with crosstalk |
Q34059313 | Genetic flexibility of regulatory networks |
Q36814155 | Harnessing mutagenic homologous recombination for targeted mutagenesis in vivo by TaGTEAM |
Q34413996 | How does evolution tune biological noise? |
Q55222050 | Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES. |
Q40168266 | In silico design and in vivo implementation of yeast gene Boolean gates |
Q47602003 | In silico design of context-responsive mammalian promoters with user-defined functionality |
Q34276083 | Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters |
Q47104409 | Influence of cis Element Arrangement on Promoter Strength in Trichoderma reesei. |
Q26830622 | Introduction and expression of genes for metabolic engineering applications in Saccharomyces cerevisiae |
Q34625287 | Measurements of the impact of 3' end sequences on gene expression reveal wide range and sequence dependent effects |
Q21145352 | Modeling structure-function relationships in synthetic DNA sequences using attribute grammars |
Q41823688 | Modeling the effect of transcriptional noise on switching in gene networks in a genetic bistable switch |
Q51150465 | Multimodality and flexibility of stochastic gene expression |
Q33970692 | Multiobjective H2/H∞ synthetic gene network design based on promoter libraries |
Q57811248 | Multiscale effects of heating and cooling on genes and gene networks |
Q24610764 | Nature, nurture, or chance: stochastic gene expression and its consequences |
Q88651426 | Negative Regulation Gene Circuits for Efflux Pump Control |
Q37125162 | Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression |
Q28485322 | New Measurement Methods of Network Robustness and Response Ability via Microarray Data |
Q39919274 | Next-generation synthetic gene networks |
Q37921682 | Noise in Biological Systems: Pros, Cons, and Mechanisms of Control |
Q33895328 | Noise-driven heterogeneity in the rate of genetic-variant generation as a basis for evolvability |
Q44307481 | On the calculation of signal transduction ability of signaling transduction pathways in intracellular communication: systematic approach |
Q91869567 | Perspective: Engineering noise in biological systems towards predictive stochastic design |
Q38019716 | Perspectives on the automatic design of regulatory systems for synthetic biology. |
Q42084694 | Physical constraints on biological integral control design for homeostasis and sensory adaptation. |
Q34350046 | Probing the effect of promoters on noise in gene expression using thousands of designed sequences |
Q28748996 | Programming cells: towards an automated 'Genetic Compiler' |
Q38034483 | Promoter engineering: Recent advances in controlling transcription at the most fundamental level |
Q37279509 | Promoters maintain their relative activity levels under different growth conditions |
Q47642069 | Protein interaction perturbation profiling at amino-acid resolution |
Q39637310 | Rational diversification of a promoter providing fine-tuned expression and orthogonal regulation for synthetic biology |
Q36895178 | Recent Progress on Systems and Synthetic Biology Approaches to Engineer Fungi As Microbial Cell Factories. |
Q36392906 | Reduction of multiscale stochastic biochemical reaction networks using exact moment derivation |
Q38092872 | Regulation of Noise in Gene Expression |
Q41852792 | Regulatory consequences of gene translocation in bacteria |
Q35610464 | Robust Design of Biological Circuits: Evolutionary Systems Biology Approach |
Q40997006 | Robust Synthetic Circuits for Two-Dimensional Control of Gene Expression in Yeast |
Q33995378 | Robust synthetic gene network design via library-based search method |
Q33592328 | Robustness and evolvability in natural chemical resistance: identification of novel systems properties, biochemical mechanisms and regulatory interactions |
Q51386095 | Stochastic Modeling of Cellular Networks |
Q33882325 | Stochastic sequence-level model of coupled transcription and translation in prokaryotes |
Q28271517 | Successes and failures in modular genetic engineering |
Q38081904 | Synthetic Biology: Advancing the Design of Diverse Genetic Systems |
Q36223937 | Synthetic Core Promoters as Universal Parts for Fine-Tuning Expression in Different Yeast Species |
Q47160645 | Synthetic Promoters and Transcription Factors for Heterologous Protein Expression in Saccharomyces cerevisiae |
Q64947796 | Synthetic Toolkit for Complex Genetic Circuit Engineering in Saccharomyces cerevisiae. |
Q57148418 | Synthetic gene regulation for independent external induction of the pseudohyphal growth phenotype |
Q36188597 | Systematic Design of a Metal Ion Biosensor: A Multi-Objective Optimization Approach |
Q33631997 | TATA is a modular component of synthetic promoters |
Q38440339 | Tailor-made transcriptional biosensors for optimizing microbial cell factories. |
Q39431299 | Taking chances and making mistakes: non-genetic phenotypic heterogeneity and its consequences for surviving in dynamic environments |
Q33351927 | Targeted development of registries of biological parts |
Q34235272 | The Transition between Stochastic and Deterministic Behavior in an Excitable Gene Circuit |
Q39065329 | The application of powerful promoters to enhance gene expression in industrial microorganisms |
Q24644242 | The incoherent feed-forward loop can generate non-monotonic input functions for genes |
Q35849058 | The relationship between stochastic and deterministic quasi-steady state approximations |
Q37790267 | The role of physiological heterogeneity in microbial population behavior. |
Q34982488 | The second wave of synthetic biology: from modules to systems |
Q38608345 | The timing of transcriptional regulation in synthetic gene circuits |
Q36516053 | Transcriptional control of noise in gene expression |
Q50742936 | Transcriptional refractoriness is dependent on core promoter architecture |
Q36614050 | Transferring a synthetic gene circuit from yeast to mammalian cells |
Q34451621 | Tunable Promoters in Synthetic and Systems Biology |
Q52724460 | Tuning Transcriptional Regulation through Signaling: A Predictive Theory of Allosteric Induction |
Q33812384 | Tuning and controlling gene expression noise in synthetic gene networks. |
Q37247748 | Tuning response curves for synthetic biology. |
Q24630346 | Tuning the dials of Synthetic Biology |
Q36889314 | Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise |
Q51891278 | Two-component genetic switch as a synthetic module with tunable stability. |
Q38943066 | Universal protein distributions in a model of cell growth and division |
Q35262704 | Using dynamic noise propagation to infer causal regulatory relationships in biochemical networks |
Q36825421 | Using noise to probe and characterize gene circuits. |
Q24655513 | Writing DNA with GenoCAD |
Search more.