Rapid Development of gp120-Focused Neutralizing B Cell Responses during Acute Simian Immunodeficiency Virus Infection of African Green Monkeys

scientific article

Rapid Development of gp120-Focused Neutralizing B Cell Responses during Acute Simian Immunodeficiency Virus Infection of African Green Monkeys is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.01564-15
P932PMC publication ID4542363
P698PubMed publication ID26157116

P50authorSallie R PermarQ87955622
Hua-Xin LiaoQ88608388
R Glenn OvermanQ114780420
P2093author name stringM Anthony Moody
Joshua D Amos
Thaddeus C Gurley
Lisa Colvin
Krista Beck
David R Martinez
Jonathon E Himes
Lawrence Armand
P2860cites workPolyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individualsQ24635002
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Co-evolution of a broadly neutralizing HIV-1 antibody and founder virusQ27644501
Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01Q27663293
Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 BindingQ27670829
Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep SequencingQ27671696
A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan ShieldQ27675032
Broad and potent neutralization of HIV-1 by a gp41-specific human antibodyQ27675131
Island biogeography reveals the deep history of SIVQ28293475
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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine targetQ29547347
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Rapid evolution of the neutralizing antibody response to HIV type 1 infectionQ29618603
Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodiesQ29619015
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1Q29619511
Neutralizing antibody responses in Africa green monkeys naturally infected with simian immunodeficiency virus (SIVagm).Q30766349
Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.Q31016954
Going wild: lessons from naturally occurring T-lymphotropic lentivirusesQ31066870
Inhibition of adaptive immune responses leads to a fatal clinical outcome in SIV-infected pigtailed macaques but not vervet African green monkeysQ33518502
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Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeysQ33597744
Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infectionQ33702217
Simian Immunodeficiency Virus Replicates to High Levels in Sooty Mangabeys without Inducing DiseaseQ33782693
Suppression of adaptive immune responses during primary SIV infection of sabaeus African green monkeys delays partial containment of viremia but does not induce disease.Q33806000
Nonpathogenic simian immunodeficiency virus infection of sooty mangabeys is not associated with high levels of autologous neutralizing antibodiesQ33877434
Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodiesQ34006748
Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sortingQ34042758
Apparent lack of vertical transmission of simian immunodeficiency virus (SIV) in naturally infected African green monkeys, Cercopithecus aethiops.Q45790312
Diagnosis of AIDS by using a 12-amino acid peptide representing an immunodominant epitope of the human immunodeficiency virusQ45848000
Prevalence of natural infection with simian immunodeficiency virus and simian T-cell leukemia virus type I in a breeding colony of sooty mangabey monkeysQ45850937
Development of the antibody response in acute HIV-1 infectionQ47747470
Progress in HIV-1 vaccine developmentQ56600657
Limited contribution of mucosal IgA to Simian immunodeficiency virus (SIV)-specific neutralizing antibody response and virus envelope evolution in breast milk of SIV-infected, lactating rhesus monkeysQ34046182
Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized miceQ34180174
Genetic identity and biological phenotype of a transmitted/founder virus representative of nonpathogenic simian immunodeficiency virus infection in African green monkeysQ34290999
Principal neutralizing domain of the human immunodeficiency virus type 1 envelope proteinQ34301897
A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1Q34306804
Simian immunodeficiency virus SIVagm.sab infection of Caribbean African green monkeys: a new model for the study of SIV pathogenesis in natural hostsQ34647780
Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremiaQ34848486
In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadthQ34937404
HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share cross-reactivity with commensal bacteriaQ34957769
Restricted isotype, distinct variable gene usage, and high rate of gp120 specificity of HIV-1 envelope-specific B cells in colostrum compared with those in blood of HIV-1-infected, lactating African womenQ35058698
Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conservedQ35073270
The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infectionQ35076717
Mother-to-Infant Transmission of Simian Immunodeficiency Virus Is Rare in Sooty Mangabeys and Is Associated with Low ViremiaQ35077005
Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaquesQ35113475
HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodiesQ35192641
High cell-free virus load and robust autologous humoral immune responses in breast milk of simian immunodeficiency virus-infected african green monkeys.Q35192646
Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestorsQ35382871
Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutatedQ35441583
A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary virusesQ35569049
Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donorsQ35857221
Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infectionQ35857268
Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman PrimatesQ35914306
Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infectionQ36423897
Paucity of CD4+ CCR5+ T cells may prevent transmission of simian immunodeficiency virus in natural nonhuman primate hosts by breast-feedingQ36673279
Broadly Neutralizing Antibodies Present New Prospects to Counter Highly Antigenically Diverse VirusesQ36693991
Characterization of plasmablasts in the blood of HIV-infected viremic individuals: evidence for nonspecific immune activationQ36827309
HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life.Q36874604
Potent simian immunodeficiency virus-specific cellular immune responses in the breast milk of simian immunodeficiency virus-infected, lactating rhesus monkeysQ36996108
Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithmQ37247974
Lack of B Cell Dysfunction Is Associated with Functional, gp120-Dominant Antibody Responses in Breast Milk of Simian Immunodeficiency Virus-Infected African Green MonkeysQ37252604
Effect of B-cell depletion on viral replication and clinical outcome of simian immunodeficiency virus infection in a natural hostQ37365356
Measuring HIV neutralization in a luciferase reporter gene assayQ39914262
HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineagesQ42270590
Mother‐to‐infant transmission of SIV via breast‐feeding in rhesus macaquesQ45198562
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectSimian immunodeficiency virusQ1890246
P304page(s)9485-9498
P577publication date2015-07-08
P1433published inJournal of VirologyQ1251128
P1476titleRapid Development of gp120-Focused Neutralizing B Cell Responses during Acute Simian Immunodeficiency Virus Infection of African Green Monkeys
P478volume89

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cites work (P2860)
Q37252913Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized in Plasma and Milk in Chronically Infected African Green Monkeys
Q37072545Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus
Q38744569Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission
Q55411829Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys.

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