Disordered purinergic signaling inhibits pathological angiogenesis in cd39/Entpd1-null mice

scientific article

Disordered purinergic signaling inhibits pathological angiogenesis in cd39/Entpd1-null mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2353/AJPATH.2007.070190
P932PMC publication ID1988887
P698PubMed publication ID17823293
P5875ResearchGate publication ID6017682

P50authorShaun W JacksonQ49598614
P2093author name stringYan Wu
Simon C Robson
Keiichi Enjyoji
Xiaofeng Sun
Christian Sundberg
Tomokazu Hoshi
Eva Cszimadia
P2860cites workDistinct antitumor properties of a type IV collagen domain derived from basement membraneQ22253901
RanBPM associates with CD39 and modulates ecto-nucleotidase activityQ24304417
Identification and characterization of CD39/vascular ATP diphosphohydrolaseQ24336540
An RGD sequence in the P2Y(2) receptor interacts with alpha(V)beta(3) integrins and is required for G(o)-mediated signal transductionQ24681126
Angiogenesis in cancer and other diseasesQ27861015
Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPMQ28216348
Antitumor activity of IFN-lambda in murine tumor modelsQ28585272
Focal adhesion kinase: the first ten yearsQ28609173
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesisQ29547178
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppressionQ29615344
Mechanisms of angiogenesis and arteriogenesisQ29617257
Seven-transmembrane receptorsQ29619896
RanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1.Q33292490
Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival.Q33835366
Signaling angiogenesis via p42/p44 MAP kinase and hypoxiaQ34047250
Nomenclature and classification of purinoceptors.Q34324355
Regulation of G protein-coupled receptor signaling by scaffold proteinsQ34973942
A2A adenosine receptor protects tumors from antitumor T cells.Q35016529
Adenosine A(2A) receptor activation promotes wound neovascularization by stimulating angiogenesis and vasculogenesis.Q35098311
Integrins in angiogenesis: multitalented molecules in a balancing act.Q35299292
Targeted antiangiogenic therapy for cancer using Vitaxin: a humanized monoclonal antibody to the integrin alphavbeta3.Q40616267
Disordered cellular migration and angiogenesis in cd39-null miceQ43826717
Integrin indecisionQ43851610
Chemotactic, mitogenic, and angiogenic actions of UTP on vascular endothelial cells.Q46436855
A mechanism for divalent cation regulation of beta 3-integrins.Q46457093
Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulationQ50336029
Fibrinogen is an important determinant of the metastatic potential of circulating tumor cellsQ52163110
Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrinsQ61631829
Assessing tumors in living animals through measurement of urinary beta-human chorionic gonadotropinQ73844711
Modulation of endothelial cell migration by extracellular nucleotides: involvement of focal adhesion kinase and phosphatidylinositol 3-kinase-mediated pathwaysQ81668348
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectangiogenesisQ539568
P304page(s)1395-1404
P577publication date2007-09-06
P1433published inThe American Journal of PathologyQ4744259
P1476titleDisordered purinergic signaling inhibits pathological angiogenesis in cd39/Entpd1-null mice
P478volume171

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cites work (P2860)
Q45848130Altered purinergic signaling in CD73-deficient mice inhibits tumor progression
Q36086478Blockade of extracellular NM23 or its endothelial target slows breast cancer growth and metastasis.
Q36906658CD39 and CD73 in immunity and inflammation
Q33917557CD39 is incorporated into plasma microparticles where it maintains functional properties and impacts endothelial activation
Q34091467CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice
Q35798953CD39: A complementary target to immune checkpoints to counteract tumor-mediated immunosuppression
Q35015717CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice
Q94464383CD73's Potential as an Immunotherapy Target in Gastrointestinal Cancers
Q37613051Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells
Q36420128Disordered purinergic signaling and abnormal cellular metabolism are associated with development of liver cancer in Cd39/Entpd1 null Mice
Q38023121ENTPD1/CD39 is a promising therapeutic target in oncology
Q37876541Ectonucleotidases as Regulators of Purinergic Signaling in Thrombosis, Inflammation, and Immunity
Q36350059Ectonucleotidases in Solid Organ and Allogeneic Hematopoietic Cell Transplantation
Q27002950Ectonucleotidases in Tumor Cells and Tumor-Associated Immune Cells: An Overview
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Q37198990Extracellular ATP and cancer: an overview with special reference to P2 purinergic receptors.
Q35546643Extracellular NM23 Signaling in Breast Cancer: Incommodus Verum
Q38870205Extracellular purines, purinergic receptors and tumor growth.
Q37279466Heightened NTPDase-1/CD39 expression and angiogenesis in radiation proctitis
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Q30504090Improved vascular organization enhances functional integration of engineered skeletal muscle grafts.
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Q46026307Multifaceted Effects of Extracellular Adenosine Triphosphate and Adenosine in the Tumor-Host Interaction and Therapeutic Perspectives.
Q34123241NTPDase3 and ecto-5'-nucleotidase/CD73 are differentially expressed during mouse bladder cancer progression
Q92637629Navigating metabolic pathways to enhance antitumour immunity and immunotherapy
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Q34542781Overexpression of CD39 in hepatocellular carcinoma is an independent indicator of poor outcome after radical resection
Q34658181P2X7 Integrates PI3K/AKT and AMPK-PRAS40-mTOR Signaling Pathways to Mediate Tumor Cell Death
Q35121379Physiologic and molecular consequences of endothelial Bmpr2 mutation
Q38058320Production of adenosine by ectonucleotidases: a key factor in tumor immunoescape
Q33770947Purinergic mechanisms in breast cancer support intravasation, extravasation and angiogenesis
Q37222633Purinergic regulation of vascular endothelial growth factor signaling in angiogenesis
Q30435545Regulated catalysis of extracellular nucleotides by vascular CD39/ENTPD1 is required for liver regeneration
Q47233864Significant Down-Regulation of "Biological Adhesion" Genes in Porcine Oocytes after IVM.
Q27650543Structural insight into signal conversion and inactivation by NTPDase2 in purinergic signaling
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Q64071654Targeting the Immunomodulatory CD73/Adenosine System to Improve the Therapeutic Gain of Radiotherapy
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Q49787788The influence of chemotherapy on adenosine-producing B cells in patients with head and neck squamous cell carcinoma
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Q97435733Using Cytometry for Investigation of Purinergic Signaling in Tumor-Associated Macrophages
Q34633667Vascular CD39/ENTPD1 Directly Promotes Tumor Cell Growth by Scavenging Extracellular Adenosine Triphosphate

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