| scholarly article | Q13442814 |
| P50 | author | Christopher K Glass | Q55458945 |
| Xingqun Liang | Q64682783 | ||
| Paola Cattaneo | Q43014746 | ||
| P2093 | author name string | Jie Yan | |
| Yunfu Sun | |||
| Sylvia M Evans | |||
| Xiaoli Zhang | |||
| Ju Chen | |||
| Cizhong Jiang | |||
| Xinkai Cao | |||
| Lei Bu | |||
| Peng Geng | |||
| Qingquan Zhang | |||
| Shaowei Zhuang | |||
| Gang Wang | |||
| Yihan Chen | |||
| Xiaodong Zhao | |||
| Tao Zhuang | |||
| Alexander C Zambon | |||
| Indroneal Banerjee | |||
| Nathanael J Spann | |||
| Lina Luo | |||
| Xiaohui Gong | |||
| H S Vincent Chen | |||
| P2860 | cites work | TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions | Q21999527 |
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| Epidemiology of sudden cardiac death: clinical and research implications | Q24650947 | ||
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| Identification and functional characterization of cardiac pacemaker cells in zebrafish | Q27313717 | ||
| Fast gapped-read alignment with Bowtie 2 | Q27860699 | ||
| Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart | Q28190508 | ||
| Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification | Q28275356 | ||
| Molecular pathway for the localized formation of the sinoatrial node | Q28284039 | ||
| Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development | Q28506813 | ||
| Neuregulin-1 promotes formation of the murine cardiac conduction system | Q28507021 | ||
| Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity | Q28508769 | ||
| Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2. | Q28584945 | ||
| The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart | Q28585488 | ||
| Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis | Q28586231 | ||
| An essential role of Bmp4 in the atrioventricular septation of the mouse heart | Q28586261 | ||
| PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes | Q28586847 | ||
| The ryanodine receptor modulates the spontaneous beating rate of cardiomyocytes during development | Q28587739 | ||
| Notch signaling regulates murine atrioventricular conduction and the formation of accessory pathways | Q28591561 | ||
| Expression of the hyperpolarization-activated cyclic nucleotide-gated cation channel HCN4 during mouse heart development | Q28591825 | ||
| Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene | Q28592688 | ||
| Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3 | Q28594589 | ||
| Distinct phases of cardiomyocyte differentiation regulate growth of the zebrafish heart | Q30487250 | ||
| Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18. | Q30544927 | ||
| Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia | Q33151337 | ||
| HCN4 dynamically marks the first heart field and conduction system precursors | Q33598169 | ||
| A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker. | Q33722486 | ||
| Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation | Q33935135 | ||
| NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids | Q34040157 | ||
| A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews. | Q34128155 | ||
| cAMP Sensitivity of HCN Pacemaker Channels Determines Basal Heart Rate But Is Not Critical for Autonomic Rate Control | Q34130292 | ||
| A high-resolution map of the three-dimensional chromatin interactome in human cells | Q34378943 | ||
| Environment drives selection and function of enhancers controlling tissue-specific macrophage identities | Q34452301 | ||
| Localization of pacemaking activity in early embryonic heart monitored using voltage-sensitive dye. | Q52293882 | ||
| Optical Monitoring of Spontaneous Electrical Activity of 8-somite Embryonic Chick Heart | Q52303015 | ||
| Formation of the Venous Pole of the Heart From an Nkx2-5-Negative Precursor Population Requires Tbx18 | Q56000972 | ||
| New recessive syndrome of microcephaly, cerebellar hypoplasia, and congenital heart conduction defect | Q56770946 | ||
| Direct Nkx2-5 Transcriptional Repression of Isl1 Controls Cardiomyocyte Subtype Identity | Q63364317 | ||
| The development of the conduction system in the mouse embryo heart | Q71398007 | ||
| Location of pacemaker in chick embryo heart at the time of initiation of heartbeat | Q72203787 | ||
| Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization | Q73853279 | ||
| Ventricular pacing or dual-chamber pacing for sinus-node dysfunction | Q74294883 | ||
| Impaired cardiac performance in heterozygous mice with a null mutation in the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 (SERCA2) gene | Q77801158 | ||
| Endothelin-1 and Neuregulin-1 convert embryonic cardiomyocytes into cells of the conduction system in the mouse | Q81505289 | ||
| A family of hyperpolarization-activated mammalian cation channels | Q34472604 | ||
| New insights into pacemaker activity: promoting understanding of sick sinus syndrome | Q34617500 | ||
| Point mutation in the HCN4 cardiac ion channel pore affecting synthesis, trafficking, and functional expression is associated with familial asymptomatic sinus bradycardia | Q34655363 | ||
| Functional redundancy between human SHOX and mouse Shox2 genes in the regulation of sinoatrial node formation and pacemaking function. | Q34947910 | ||
| RNA sequencing of mouse sinoatrial node reveals an upstream regulatory role for Islet-1 in cardiac pacemaker cells | Q35132359 | ||
| Isl1 is required for multiple aspects of motor neuron development | Q35432551 | ||
| HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice | Q36116647 | ||
| GO-Elite: a flexible solution for pathway and ontology over-representation | Q36145842 | ||
| Voltage-dependent calcium channels and cardiac pacemaker activity: from ionic currents to genes | Q36175118 | ||
| Stem cells as biological heart pacemakers | Q36327036 | ||
| Endothelin-induced conversion of embryonic heart muscle cells into impulse-conducting Purkinje fibers | Q36490548 | ||
| The integration of spontaneous intracellular Ca2+ cycling and surface membrane ion channel activation entrains normal automaticity in cells of the heart's pacemaker. | Q36667321 | ||
| Induction of Purkinje fiber differentiation by coronary arterialization | Q36668306 | ||
| Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders | Q36968428 | ||
| Dynamic interactions of an intracellular Ca2+ clock and membrane ion channel clock underlie robust initiation and regulation of cardiac pacemaker function | Q37002243 | ||
| Biological pacemaker created by minimally invasive somatic reprogramming in pigs with complete heart block. | Q37105417 | ||
| Genesis and regulation of the heart automaticity. | Q37216067 | ||
| Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5. | Q37222054 | ||
| Development of the pacemaker tissues of the heart. | Q37687712 | ||
| Effect of natural genetic variation on enhancer selection and function. | Q38866012 | ||
| A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells | Q39483876 | ||
| A large permissive regulatory domain exclusively controls Tbx3 expression in the cardiac conduction system. | Q39552302 | ||
| The transcriptional repressor Tbx3 delineates the developing central conduction system of the heart. | Q40553027 | ||
| Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia | Q41136701 | ||
| Phosphorylation and regulation of the Ca(2+)-pumping ATPase in cardiac sarcoplasmic reticulum by calcium/calmodulin-dependent protein kinase | Q41514087 | ||
| Intracellular Ca2+ oscillations, a potential pacemaking mechanism in early embryonic heart cells | Q41863784 | ||
| Tamoxifen-inducible gene deletion in the cardiac conduction system | Q42437141 | ||
| Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells | Q43243916 | ||
| Replacement of the muscle-specific sarcoplasmic reticulum Ca(2+)-ATPase isoform SERCA2a by the nonmuscle SERCA2b homologue causes mild concentric hypertrophy and impairs contraction-relaxation of the heart | Q43778748 | ||
| The sinus venosus progenitors separate and diversify from the first and second heart fields early in development | Q44464144 | ||
| Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression | Q44810019 | ||
| Role of HCN4 channel in preventing ventricular arrhythmia | Q45804174 | ||
| Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation | Q45823928 | ||
| Pinch1 is required for normal development of cranial and cardiac neural crest-derived structures. | Q45957952 | ||
| Sarcoplasmic reticulum Ca(2+)-ATPase overexpression by adenovirus mediated gene transfer and in transgenic mice | Q46112930 | ||
| Mesenchymal stem cells as a gene delivery system to create biological pacemaker cells in vitro | Q47315174 | ||
| T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells. | Q51803470 | ||
| Molecular analysis of patterning of conduction tissues in the developing human heart. | Q51867176 | ||
| Notch1b and neuregulin are required for specification of central cardiac conduction tissue. | Q52025862 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | RNA sequencing | Q2542347 |
| P304 | page(s) | 3256-3268 | |
| P577 | publication date | 2015-07-20 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Transcription factor ISL1 is essential for pacemaker development and function | |
| P478 | volume | 125 |
| Q89068535 | Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development |
| Q64238176 | Collaborative ISL1/GATA3 interaction in controlling neuroblastoma oncogenic pathways overlapping with but distinct from MYCN |
| Q49923297 | Comparative developmental biology of the cardiac inflow tract. |
| Q39347586 | Concise Review: Criteria for Chamber-Specific Categorization of Human Cardiac Myocytes Derived from Pluripotent Stem Cells |
| Q92495861 | Correlations between ISL1 rs1017 polymorphism and congenital heart disease risk: A PRISMA-compliant meta-analysis |
| Q45262771 | Development and Function of the Cardiac Conduction System in Health and Disease |
| Q38987999 | Development of the cardiac pacemaker |
| Q36372470 | Genetic Regulation of Sinoatrial Node Development and Pacemaker Program in the Venous Pole |
| Q92732166 | HIF-1α is required for development of the sympathetic nervous system |
| Q92217593 | Hand2 Selectively Reorganizes Chromatin Accessibility to Induce Pacemaker-like Transcriptional Reprogramming |
| Q67471784 | High-resolution transcriptional dissection of in vivo Atoh1-mediated hair cell conversion in mature cochleae identifies Isl1 as a co-reprogramming factor. |
| Q37210954 | ISL1 and JMJD3 synergistically control cardiac differentiation of embryonic stem cells |
| Q90397440 | Identification and Functional Characterization of an ISL1 Mutation Predisposing to Dilated Cardiomyopathy |
| Q93357355 | Insulin gene enhancer binding protein 1 induces adipose tissue‑derived stem cells to differentiate into pacemaker‑like cells |
| Q92835974 | Iran's Contribution to Human Proteomic Research |
| Q46520695 | Isl1 mediates mesenchymal expansion in the developing external genitalia via regulation of Bmp4, Fgf10, and Wnt5a. |
| Q46744561 | Mammalian γ2 AMPK regulates intrinsic heart rate |
| Q47841255 | Mutations in Hnrnpa1 cause congenital heart defects |
| Q38649331 | New Approaches to Biological Pacemakers: Links to Sinoatrial Node Development |
| Q55019102 | No effect of thymosin beta-4 on the expression of the transcription factor Islet-1 in the adult murine heart. |
| Q48172096 | On the Evolution of the Cardiac Pacemaker |
| Q50420940 | Prospective Isolation of ISL1+ Cardiac Progenitors from Human ESCs for Myocardial Infarction Therapy. |
| Q50048221 | Protein Kinase 2β Is Expressed in Neural Crest-Derived Urinary Pacemaker Cells and Required for Pyeloureteric Contraction |
| Q46425614 | Same-Single-Cell Analysis of Pacemaker-Specific Markers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Subtypes Classified by Electrophysiology. |
| Q97537622 | Silencing miR-370-3p rescues funny current and sinus node function in heart failure |
| Q48106167 | Spatially resolved RNA-sequencing of the embryonic heart identifies a role for Wnt/β-catenin signaling in autonomic control of heart rate. |
| Q38920721 | Spatiotemporal regulation of enhancers during cardiogenesis |
| Q42379949 | Tbx18 and the generation of a biological pacemaker. Are we there yet? |
| Q51419661 | Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification. |
| Q26770904 | The formation and function of the cardiac conduction system |
| Q90213929 | Transcription Factor prrx1 Promotes Brown Adipose-Derived Stem Cells Differentiation to Sinus Node-Like Cells |
| Q89014504 | Transcriptional regulation of the cardiac conduction system |
| Q38695345 | Transient Notch Activation Induces Long-Term Gene Expression Changes Leading to Sick Sinus Syndrome in Mice |
| Q48183264 | nkx genes establish SHF cardiomyocyte progenitors at the arterial pole and pattern the venous pole through Isl1 repression. |
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