Acute myeloid leukemia with a complex aberrant karyotype is a distinct biological entity characterized by genomic imbalances and a specific gene expression profile

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Acute myeloid leukemia with a complex aberrant karyotype is a distinct biological entity characterized by genomic imbalances and a specific gene expression profile is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/GCC.20193
P698PubMed publication ID15846790

P50authorTorsten HaferlachQ66370751
Claudia SchochQ66370757
Susanne SchnittgerQ66370791
P2093author name stringAlexander Kohlmann
Wolfgang Kern
Wolfgang Hiddemann
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De novo erythroleukemia chromosome features include multiple rearrangements, with special involvement of chromosomes 11 and 19.Q38485176
Loss of genetic material is more common than gain in acute myeloid leukemia with complex aberrant karyotype: a detailed analysis of 125 cases using conventional chromosome analysis and fluorescence in situ hybridization including 24-color FISH.Q38487721
Spectral karyotyping in patients with acute myeloid leukemia and a complex karyotype shows hidden aberrations, including recurrent overrepresentation of 21q, 11q, and 22q.Q38489443
Cross-species color banding in ten cases of myeloid malignancies with complex karyotypesQ38495027
Karyotyping human chromosomes by combinatorial multi-fluor FISH.Q38507389
Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignanciesQ40639306
The coloring of cytogeneticsQ40929860
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AML with 11q23/MLL abnormalities as defined by the WHO classification: incidence, partner chromosomes, FAB subtype, age distribution, and prognostic impact in an unselected series of 1897 cytogenetically analyzed AML casesQ44885054
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Karyotype is an independent prognostic parameter in therapy-related acute myeloid leukemia (t-AML): an analysis of 93 patients with t-AML in comparison to 1091 patients with de novo AMLQ47414654
Identification of cytogenetic subclasses and recurring chromosomal aberrations in AML and MDS with complex karyotypes using m‐FISHQ49054744
Further characterization of complex chromosomal rearrangements in myeloid malignancies: spectral karyotyping adds precision in defining abnormalities associated with poor prognosis.Q49279882
Dependence of age-specific incidence of acute myeloid leukemia on karyotypeQ59529896
Cytogenetics and their prognostic value in de novo acute myeloid leukaemia: a report on 283 casesQ69774388
Fourth International Workshop on Chromosomes in Leukemia 1982: Clinical significance of chromosomal abnormalities in acute nonlymphoblastic leukemiaQ71293257
Long-term survival in acute myelogenous leukemia: a second follow-up of the Fourth International Workshop on Chromosomes in LeukemiaQ72399666
Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognoQ73567637
Screening for MLL tandem duplication in 387 unselected patients with AML identify a prognostically unfavorable subset of AMLQ73769144
Balanced chromosome aberrations in leukemias following chemotherapy with DNA-topoisomerase II inhibitorsQ74546041
Allelotyping of acute myelogenous leukemia: loss of heterozygosity at 7q31.1 (D7S486) and q33-34 (D7S498, D7S505)Q74593023
P433issue3
P921main subjectacute myeloid leukemiaQ264118
leukemiaQ29496
karyotypeQ189967
P304page(s)227-238
P577publication date2005-07-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inGenes, Chromosomes and CancerQ5532697
P1476titleAcute myeloid leukemia with a complex aberrant karyotype is a distinct biological entity characterized by genomic imbalances and a specific gene expression profile
P478volume43

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